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Showing results 1-15 of 15

2017
1 Han, Sangdon; Thoresen, Lars; Jung, Jae-Kyu; Zhu, Xiuwen; Thatte, Jayant; Solomon, Michelle; Gaidarov, Ibragim; Unett, David J.; Yoon, Woo Hyun; Barden, Jeremy; Sadeque, Abu; Usmani, Amin; Chen, Chuan; Semple, Graeme; Grottick, Andrew J.; Al-Shamma, Hussien; Christopher, Ronald J.; Jones, Robert M..
Discovery of APD371: Identification of a Highly Potent and Selective CB2 Agonist for the Treatment of Chronic Pain. ACS Medicinal Chemistry Letters 2017 ;Volume 8.(12) p. 1309-1313
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2015
2 Han, Sangdon; Thoresen, Lars; Zhu, Xiuwen; Narayanan, Sanju; Jung, Jae-Kyu; Strah-Pleynet, Sonja; Decaire, Marc; Choi, Karoline; Xiong, Yifeng; Yue, Dawei; Semple, Graeme; Thatte, Jayant; Solomon, Michelle; Fu, Lixia; Whelan, Kevin; Al-Shamma, Hussien; Gatlin, Joel; Chen, Ruoping; Dang, Huong; Pride, Cameron; Gaidarov, Ibragim; Unett, David J.; Behan, Dominic P.; Sadeque, Abu; Usmani, Khawja A.; Chen, Chuan; Edwards, Jeffrey; Morgan, Michael; Jones, Robert M..
Discovery of 1a,2,5,5a-tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalen-4-carboxamides as potent and selective CB2 receptor agonists. Bioorganic & Medicinal Chemistry Letters 2015 ;Volume 25.(2) p. 322-326
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2014
3 Buzard, Daniel J.; Kim, Sun Hee; Lopez, Luis; Kawasaki, Andrew; Zhu, Xiuwen; Moody, Jeanne; Thoresen, Lars; Calderon, Imelda; Ullman, Brett; Han, Sangdon; Lehmann, Juerg; Gharbaoui, Tawfik; Sengupta, Dipanjan; Calvano, Lorene; Montalban, Antonio Garrido; Ma, You-An; Sage, Carleton; Gao, Yinghong; Semple, Graeme; Edwards, Jeff; Barden, Jeremy; Morgan, Michael; Chen, Weichao; Usmani, Khawja A.; Chen, Chuan; Sadeque, Abu; Christopher, Ronald J.; Thatte, Jayant; Fu, Lixia; Solomon, Michelle; Mills, David; Whelan, Kevin; Al-Shamma, Hussien.
Discovery of APD334: Design of a Clinical Stage Functional Antagonist of the Sphingosine-1-phosphate-1 Receptor. ACS Medicinal Chemistry Letters 2014 ;Volume 5.(12) p. 1313-1317
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4 Buzard, Daniel J.; Lopez, Luis; Kawasaki, Andrew; Schrader, Thomas O.; Kasem, Michelle; Johnson, Ben; Zhu, Xiuwen; Thoresen, Lars; Kim, Sun Hee; Gharbaoui, Tawfik; Sengupta, Dipanjan; Calvano, Lorene; Krishnan, Ashwin; Gao, Yinghong; Semple, Graeme; Edwards, Jeff; Barden, Jeremy; Morgan, Michael; Usmani, Khawja; Chen, Chuan; Sadeque, Abu; Chen, Weichao; Christopher, Ronald J.; Thatte, Jayant; Fu, Lixia; Solomon, Michelle; Whelan, Kevin; Al-Shamma, Hussien; Gatlin, Joel; Gaidarov, Ibragim; Anthony, Todd; Le, Minh; Unett, David J.; Blackburn, Anthony; Stirn, Scott; Jones, Robert M.; Behan, Dominic P..
(7-Benzyloxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetic Acids as S1P1Functional Antagonists. ACS Medicinal Chemistry Letters 2014 ;Volume 5.(12) p. 1334-1339
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2012
5 Buzard, Daniel J.; Han, Sangdon; Lopez, Luis; Kawasaki, Andrew; Moody, Jeanne; Thoresen, Lars; Ullman, Brett; Lehmann, Juerg; Calderon, Imelda; Zhu, Xiuwen; Tawfik, Gharbaoui; Sengupta, Dipanjan; Krishnan, Ashwin; Gao, Yinghong; Edwards, Jeff; Barden, Jeremy; Morgan, Michael; Usmani, Khawja; Chen, Chuan; Sadeque, Abu; Thatte, Jayant; Solomon, Michelle; Fu, Lixia; Al-Shamma, Hussien; Gatlin, Joel; Le, Minh; Xing, Charles; Espinola, Sheryll; Jones, Robert M..
Fused tricyclic indoles as S1P1 agonists with robust efficacy in animal models of autoimmune disease. Bioorganic & Medicinal Chemistry Letters 2012 ;Volume 22.(13) p. 4404-4409
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2011
6 Buzard, Daniel; Han, Sangdon; Thoresen, Lars; Moody, Jeanne; Lopez, Luis; Kawasaki, Andrew; Schräder, Thomas; Sage, Carleton; Gao, Yinghong; Edwards, Jeff; Barden, Jeremy; Thatte, Jayant; Fu, Lixia; Solomon, Michelle; Liu, Ling; Al-Shamma, Hussien; Gatlin, Joel; Le, Minh; Xing, Charles; Espinola, Sheryll; Jones, Robert M..
Discovery and characterization of potent and selective 4-oxo-4-(5-(5-phenyl-1,2,4-oxadiazol-3-yl)indolin-1-yl)butanoic acids as S1P1 agonists. Bioorganic & Medicinal Chemistry Letters 2011 ;Volume 21.(19) p. 6013-6018
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2006
7 Guan-Sheng, Jiao; Thoresen, Lars; Kim, Taeg Gyum; Haaland, Wade C.; Gao, Feng; Topp, Michael R.; Hochstrasser, Robin M.; Metzker, Michael L.; Burgess, Kevin.
Syntheses, Photophysical Properties, and Application of Through‐Bond Energy‐Transfer Cassettes for Biotechnology. Chemistry - A European Journal 2006 ;Volume 12.(30) p. 7816-7826
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2003
8 Guan-Sheng, Jiao; Castro, Juan C.; Thoresen, Lars; Burgess, Kevin.
Microwave-Assisted Syntheses of Regioisomerically Pure Bromorhodamine Derivatives. Organic Letters 2003 ;Volume 5.(20) p. 3675-3677
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9 Guan-Sheng, Jiao; Thoresen, Lars; Burgess, Kevin.
Fluorescent, Through-Bond Energy Transfer Cassettes for Labeling Multiple Biological Molecules in One Experiment. Journal of the American Chemical Society 2003 ;Volume 125.(48) p. 14668-14669
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10 Thoresen, Lars; Guan-Sheng, Jiao; Haaland, Wade C.; Metzker, Michael L.; Burgess, Kevin.
Rigid, Conjugated, Fluoresceinated Thymidine Triphosphates: Syntheses and Polymerase Mediated Incorporation into DNA Analogues. Chemistry - A European Journal 2003 ;Volume 9.(19) p. 4603-4610
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2002
11 Koch, Stacie S. Canan; Thoresen, Lars; et al, (25 authors totally).
Novel Tricyclic Poly(ADP-ribose) Polymerase-1 Inhibitors with Potent Anticancer Chemopotentiating Activity:  Design, Synthesis, and X-ray Cocrystal Structure. Journal of Medicinal Chemistry 2002 ;Volume 45.(23) p. 4961-4974
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2000
12 Burghart, Armin; Thoresen, Lars; Chen, Jiong; Burgess, Kevin; Bergström, Fredrik; Johansson, Lennart B.-Å..
Energy transfer cassettes based on BODIPY® dyes. Chemical Communications 2000 (22) p. 2203-2204
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1999
13 Burghart, Armin; Kim, Heejin; Welch, Mike B.; Thoresen, Lars; Reibenspies, Joe; Burgess, Kevin; Bergström, Fredrik; Johansson, Lennart B.-Å..
3,5-Diaryl-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene(BODIPY) Dyes:  Synthesis, Spectroscopic, Electrochemical, and Structural Properties. Journal of Organic Chemistry 1999 ;Volume 64.(21) p. 7813-7819
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14 Martinez, Carlos I.; Thoresen, Lars; Burgess, Kevin; Gibbs, Richard A..
An allylic/acyclic adenosine nucleoside triphosphate for termination of DNA synthesis by DNA template-dependent polymerases. Nucleic Acids Research 1999 ;Volume 27.(5) p. 1271-1274
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1998
15 Thoresen, Lars; Kim, Heejin; Welch, Mike B.; Burghart, Armin; Burgess, Kevin.
Synthesis of 3,5-Diaryl-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY®) Dyes. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry 1998 ;Volume 11. p. 1276-1278
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