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Showing results 1-40 of 40

2024
1 Unger, Lucas; Ghila, Luiza Mihaela; Chera, Simona.
Targeted Gene Silencing by Using GapmeRs in Differentiating Human-Induced Pluripotent Stem Cells (hiPSC) Toward Pancreatic Progenitors. Methods in molecular biology 2024 ;Volume 2736. p. 23-38
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2 Wang, Chencheng; Abadpour, Shadab; Olsen, Petter Angell; Wang, Daxin; Stokowiec, Justyna; Chera, Simona; Ghila, Luiza Mihaela; Ræder, Helge; Krauss, Stefan Johannes Karl; Aizenshtadt, Aleksandra; Scholz, Hanne.
Glucose Concentration in Regulating Induced Pluripotent Stem Cells Differentiation Toward Insulin-Producing Cells. Transplant International 2024 ;Volume 37. p. -
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2023
3 Daian, Laura Maria; Tanko, Gabriela; Vacaru, Andrei Mircea; Ghila, Luiza Mihaela; Chera, Simona; Vacaru, Ana-Maria.
Modulation of Unfolded Protein Response Restores Survival and Function of β-Cells Exposed to the Endocrine Disruptor Bisphenol A. International Journal of Molecular Sciences 2023 ;Volume 24.(3) p. -
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4 Hossain, Md Kaykobad; Altankhuyag, Altanchimeg; Legøy, Thomas Aga; Chera, Simona; Ghila, Luiza Mihaela.
Mapping predictive bladder cancer signatures in a mouse model. CCBIO’s 11th Annual Symposium; 2023-05-08 - 2023-05-10
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5 Unger, Lucas; Legøy, Thomas Aga; Chera, Simona; Ghila, Luiza Mihaela.
Exploring the role of transcription factors HNF1A, HNF1B, and HNF4A in human pancreatic islet cell differentiation. 57th Annual Meeting of the Scandinavian Society for the Study of Diabetes (SSSD2023); 2023-05-24 - 2023-05-26
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6 Legøy, Thomas Aga; Mathisen, Andreas Frøslev; Paulo, Joao; Unger, Lucas; Ghila, Luiza Mihaela; Chera, Simona.
Human induced pluripotent stem cells as a model for environmental impact on diabetes. Pancreatic Diseases GRS Mechanisms and Therapeutics in Pancreatic Diseases; 2023-04-29 - 2023-04-30
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7 Mathisen, Andreas Frøslev; Abadpour, Shadab; Legøy, Thomas Aga; Paulo, Joao A.; Ghila, Luiza Mihaela; Scholz, Hanne; Chera, Simona.
Global proteomics reveals insulin abundance as a marker of human islet homeostasis alterations. Acta Physiologica 2023 ;Volume 239.(2) p. -
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8 Mathisen, Andreas Frøslev; Legøy, Thomas Aga; Larsen, Ulrik; Ghila, Luiza Mihaela; Chera, Simona.
Hnf1a Is An Important Regulator in Ageing And Maturation Of Pancreatic Islets. 57th Annual Meeting of the Scandinavian Society for the Study of Diabetes (SSSD2023); 2023-05-24 - 2023-05-26
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9 Mathisen, Andreas Frøslev; Legøy, Thomas Aga; Larsen, Ulrik; Ghila, Luiza Mihaela; Chera, Simona.
Islet maturation and ageing is governed by the Hnf1a transcription factor. EASD2023; 2023-10-02 - 2023-10-06
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10 Sharmine, Shayla; Legøy, Thomas Aga; Mathisen, Andreas Frøslev; Ghila, Luiza Mihaela; Chera, Simona.
Mapping islet architecture changes upon high fat diet challenge in a HNF1A-MODY mouse model. Diabetesforum 2023; 2023-04-25 - 2023-04-27
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11 Unger, Lucas; Legøy, Thomas Aga; Ghila, Luiza Mihaela; Chera, Simona.
Exploring the role of transcription factors HNF1A, HNF1B, and HNF4A in human induced pluripotent stem cell-derived pancreatic islet cell differentiation. European Association for the Study of Diabetes Annual meeting; 2023-10-02 - 2023-10-06
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12 Unger, Lucas; Legøy, Thomas Aga; Mathisen, Andreas Frøslev; Ghila, Luiza Mihaela; Chera, Simona.
Investigating the developmental role of HNF1A, HNF1B and HNF4A in human pancreatic islet cell differentiation. 17th Annual Research Presentation Conference; 2023-01-25 - 2023-01-27
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2022
13 Bhagchandani, Preksha; Chang, Charles A.; Zhao, Weichen; Ghila, Luiza Mihaela; Herrera, Pedro L.; Chera, Simona; Kim, Seung K..
Islet cell replacement and transplantation immunology in a mouse strain with inducible diabetes. Scientific Reports 2022 ;Volume 12.(1) p. -
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14 Fernandez, Manuel Carrasco; Wang, Chencheng; Søviknes, Anne Mette; Bjørlykke, Yngvild; Abadpour, Shadab; Paulo, Joao A.; Tjora, Erling; Njølstad, Pål Rasmus; Ghabayen, Jonas; Nermoen, Ingrid; Lyssenko, Valeriya; Chera, Simona; Ghila, Luiza Mihaela; Vaudel, Marc; Scholz, Hanne; Ræder, Helge.
Spatial Environment Affects HNF4A Mutation-Specific Proteome Signatures and Cellular Morphology in hiPSC-Derived β-Like Cells. Diabetes 2022 ;Volume 71.(4) p. 862-869
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15 Ghila, Luiza Mihaela.
Chronically Elevated Exogenous Glucose Elicits Antipodal Effects on the Proteome Signature of Differentiating Human iPSC-Derived Pancreatic Progenitors. 8th International Caparica Conference on Analytical Proteomics; 2022-07-18 - 2022-07-21
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16 Ghila, Luiza Mihaela.
Mapping tumour heterogeneity and predictive cancer signatures in vivo. Cellular plasticity in homeostasis and disease Workshop; 2022-11-07 - 2022-11-09
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17 Ghila, Luiza Mihaela; Furuyama, Kenichiro; Grey, Shane T.; Scholz, Hanne; Chera, Simona.
Editorial: Beta-Cell Fate: From Gene Circuits to Disease Mechanisms. Frontiers in Genetics 2022 ;Volume 13. p. -
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18 Legøy, Thomas Aga; Mathisen, Andreas Frøslev; Scholz, Hanne; Paulo, Joao; Ræder, Helge; Ghila, Luiza Mihaela; Chera, Simona.
Molecular mechanisms affecting islet like cell fate acquisition in differentiating iPSC derived β-like cells”. European Islet Study Group Workshop; 2022-06-13 - 2022-06-15
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19 Mathisen, Andreas Frøslev; Legøy, Thomas Aga; Ghila, Luiza Mihaela; Chera, Simona.
Hnf1a is a key regulator of β-cell identity and function. Diabesity Nordic Meeting; 2022-03-09 - 2022-03-11
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20 Mathisen, Andreas Frøslev; Legøy, Thomas Aga; Ghila, Luiza Mihaela; Chera, Simona.
Know your background, know your data. 3rd Nordic Meeting on Development, Stem Cells and Regeneration; 2022-10-05 - 2022-10-07
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21 Mathisen, Andreas Frøslev; Legøy, Thomas Aga; Ghila, Luiza Mihaela; Chera, Simona.
Mind your background!. European Islet Study Group Workshop (EISG); 2022-06-13 - 2022-06-15
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22 Unger, Lucas; Ghila, Luiza Mihaela; Chera, Simona.
Investigating the developmental role of HNF1A, HNF1B and HNF4A in human pancreatic islet cell differentiation. 3rd Nordic Meeting on Development, Stem Cells and Regeneration; 2022-10-05 - 2022-10-07
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23 Unger, Lucas; Legøy, Thomas Aga; Ghila, Luiza Mihaela; Chera, Simona.
Investigating the developmental role of HNF1A in human pancreatic islet cell differentiation. Summer School in Transcriptomics; 2022-06-27 - 2022-06-30
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2021
24 Bhagchandani, Preksha; Chang, Charles; Zhao, Weichen; Ghila, Luiza Mihaela; Herrera, Pedro L.; Chera, Simona; Kim, Seung.
Islet transplantation tolerance in animals with defined histocompatibility and diabetes. bioRxiv 2021
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25 Ghila, Luiza; Legøy, Thomas Aga; Chera, Simona.
A Method for Encapsulation and Transplantation into Diabetic Mice of Human Induced Pluripotent Stem Cells (hiPSC)-Derived Pancreatic Progenitors. Methods in molecular biology 2021
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26 Ghila, Luiza; Legøy, Thomas Aga; Mathisen, Andreas Frøslev; Abadpour, Shadab; Paulo, Joao A.; Scholz, Hanne Bjørnson; Ræder, Helge; Chera, Simona.
Chronically elevated exogenous glucose elicits antipodal effects on the proteome signature of differentiating human ipsc-derived pancreatic progenitors. International Journal of Molecular Sciences 2021 ;Volume 22.(7)
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27 Wang, Chencheng; Abadpour, Shadab; Aizenshtadt, Alexandra; Chera, Simona; Ghila, Luiza Mihaela; Ræder, Helge; Scholz, Hanne.
Glucose during in vitro pancreatic beta cells regeneration: friends or for?. International Society for Stem Cell Research, 2021 annual meeting; 2021-06-23 - 2021-06-26
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28 Wang, Chencheng; Abadpour, Shadab; Aizenshtadt, Alexandra; Chera, Simona; Ghila, Luiza Mihaela; Ræder, Helge; Scholz, Hanne.
402.2: High Glucose Concentration Increases KATP Channel Activity but Suppresses Mitochondrial Respiration Ability in Insulin-producing Cells Regenerated From Stem Cells. Transplantation 2021 (12) p. S27-S27
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2020
29 Ghila, Luiza; Bjørlykke, Yngvild; Legøy, Thomas Aga; Vethe, Heidrun; Furuyama, Kenichiro; Chera, Simona; Ræder, Helge.
Bioinformatic analyses of miRNA-mRNA signature during hiPSC differentiation towards insulin-producing cells upon HNF4α mutation. Biomedicines 2020 ;Volume 8.(7) p. 1-20
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30 Legøy, Thomas Aga; Mathisen, Andreas Frøslev; Salim, Zaidon; Vethe, Heidrun; Bjørlykke, Yngvild; Abadpour, Shadab; Paulo, Joao; Scholz, Hanne; Ræder, Helge; Ghila, Luiza; Chera, Simona.
In vivo environment swiftly restricts human pancreatic progenitors toward mono-hormonal identity via a HNF1A/HNF4A mechanism. Frontiers in Cell and Developmental Biology 2020 ;Volume 8:109. p. 1-14
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31 Legøy, Thomas Aga; Vethe, Heidrun; Abadpour, Shadab; Strand, Berit Løkensgard; Scholz, Hanne; Paulo, Joao A.; Ræder, Helge; Ghila, Luiza; Chera, Simona.
Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling. Scientific Reports 2020 ;Volume 10. p. 1-16
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2019
32 Bjørlykke, Yngvild; Søviknes, Anne Mette; Hoareau, Laurence; Vethe, Heidrun; Mathisen, Andreas; Chera, Simona; Vaudel, Marc; Ghila, Luiza; Ræder, Helge.
Reprogrammed cells display distinct proteomic signaturesAssociated with colony morphology variability. Stem Cells International 2019 ;Volume 2019. p. 1-16
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33 Cigliola, Valentina; Ghila, Luiza; Chera, Simona; Herrera, Pedro L..
Tissue repair brakes: A common paradigm in the biology of regeneration: Concise review. Stem Cells 2019 ;Volume 38.(3) p. 330-339
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34 Furuyama, Kenichiro; Chera, Simona; van Gurp, Leon; Oropeza, Daniel; Ghila, Luiza; Damond, Nicolas; Vethe, Heidrun; Paulo, Joao A.; Joosten, Antoinette M.; Berney, Thierry; Bosco, Domenico; Dorrell, Craig; Grompe, Markus; Ræder, Helge; Roep, Bart O.; Thorel, Fabrizio; Herrera, Pedro L..
Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells. Nature 2019 ;Volume 567.(7746) p. 43-48
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35 Legøy, Thomas Aga; Ghila, Luiza; Vethe, Heidrun; Abadpour, Shadab; Mathisen, Andreas Frøslev; Paulo, Joao A.; Scholz, Hanne; Ræder, Helge; Chera, Simona.
In vivo hyperglycemia exposure elicits distinct period-dependent effects on human pancreatic progenitor differentiation, conveyed by oxidative stress. Acta Physiologica 2019 ;Volume 23:247577. p. 1-16
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36 Vethe, Heidrun; Ghila, Luiza; Berle, Magnus; Hoareau, Laurence; Haaland, Øystein Ariansen; Scholz, Hanne; Paulo, Joao A.; Chera, Simona; Ræder, Helge.
The effect of WnT pathway modulators on human iPSC-derived pancreatic beta cell maturation. Frontiers in Endocrinology 2019 ;Volume 10:293.(MAY) p. 1-13
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37 Vethe, Heidrun; Legøy, Thomas Aga; Abadpour, Shadab; Strand, Berit Løkensgard; Scholz, Hanne; Paulo, Joao A.; Ræder, Helge; Ghila, Luiza; Chera, Simona.
Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling. bioRxiv 2019
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2018
38 Berle, Magnus; Ghila, Luiza; Vethe, Heidrun; Chaudhry, Beenish Adeel; Garberg, Hilde Kristin; Beisland, Christian; Haaland, Øystein Ariansen; Oveland, Eystein; Halvorsen, Ole Johan; Davidsson, Thomas; Chera, Simona.
Novel protein signatures suggest progression to muscular invasiveness in bladder cancer. PLOS ONE 2018 ;Volume 13:e0206475.(11) p. 1-15
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39 Cigliola, Valentina; Ghila, Luiza; Thorel, Fabrizio; van Gurp, Leon; Baronnier, Delphine; Oropeza, Daniel; Gupta, Simone; Miyatsuka, Takeshi; Kaneto, Hideaki; Magnuson, Mark A; Osipovich, Anna B; Sander, Maike; Wright, Christopher EV; Thomas, Melissa K; Furuyama, Kenichiro; Chera, Simona; Herrera, Pedro L..
Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon+ α-cells. Nature Cell Biology 2018 ;Volume 20.(11) p. 1267-1277
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2017
40 Vethne, Heidrun; Bjørlykke, Yngvild; Ghila, Luiza; Paulo, Joao A.; Scholz, Hanne; Gygi, Steven P.; Chera, Simona; Ræder, Helge.
Probing the missing mature β-cell proteomic landscape in differentiating patient iPSC-derived cells. Scientific Reports 2017 ;Volume 7:4780. p. 1-14
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