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2019
1 Aareskjold, Elin; Grindheim, Ann Kari; Hollås, Hanne; Goris, Marianne; Lillehaug, Johan R.; Vedeler, Anni.
Two tales of Annexin A2 knock-down: One of compensatory effects by antisense RNA and another of a highly active hairpin ribozyme. Biochemical Pharmacology 2019 ;Volum 166. s. 253-263
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2 Turcu, Diana Cornelia; Lillehaug, Johan R.; Seo, Hee-Chan.
SIX3 and SIX6 interact with GEMININ via C-terminal regions. Biochemistry and Biophysics Reports 2019 ;Volum 20.
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2014
3 Johnson, Kenneth; Ve, Thomas; Larsen, Øivind; Pedersen, Rolf B.; Lillehaug, Johan R.; Jensen, Harald B; Helland, Ronny; Karlsen, Odd Andre.
CorA is a copper repressible surface-associated copper(I)-binding protein produced in Methylomicrobium album BG8. PLOS ONE 2014 ;Volum 9.(2:e87750)
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2013
4 Astori, Audrey; Fredly, Hanne Kristin; Aloysius, Thomas Aquinas; Bullinger, Lars; Mansat-De Mas, Véronique; de la Grange, Pierre; Delhommeau, François; Hagen, Karen Marie; Récher, Christian; Dusanter-Fourt, Isabelle; Knappskog, Stian; Lillehaug, Johan R.; Pendino, Frederic; Bruserud, Øystein.
CXXC5 (retinoid-inducible nuclear factor, RINF) is a potential therapeutic target in high-risk human acute myeloid leukemia. OncoTarget 2013 ;Volum 4.(9) s. 1438-1448
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5 Berge, Elisabet Ognedal; Huun, Johanna; Lillehaug, Johan R.; Lønning, Per Eystein; Knappskog, Stian.
Functional characterisation of p53 mutants identified in breast cancers with suboptimal responses to anthracyclines or mitomycin. Biochimica et Biophysica Acta - General Subjects 2013 ;Volum 1830.(3) s. 2790-2797
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6 Birkeland, Einar Elvbakken; Busch, Christian; Berge, Elisabet Ognedal; Geisler, Jürgen; Jonsson, Göran; Lillehaug, Johan R.; Knappskog, Stian; Lønning, Per Eystein.
Low BRAF and NRAS expression levels are associated with clinical benefit from DTIC therapy and prognosis in metastatic melanoma. Clinical and Experimental Metastasis 2013 ;Volum 30.(7) s. 867-876
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2012
7 Dalva, Monica; Hole, Kristine; Van Damme, Petra; Aksnes, Henriette; Nina, Glomnes; Varhaug, Jan Erik; Lillehaug, Johan R.; Kris, gevaert; Arnesen, Thomas.
The Human N-Alpha-Acetyltransferase 40 (hNaa40p/hNatD) Is Conserved from Yeast and N-Terminally Acetylates Histones H2A and H4. NBS contact meeting 2012; 2012-01-19 - 2012-01-22
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8 Evjenth, Rune Henrik; Brenner, Annette; Thompson, Paul R.; Arnesen, Thomas; Frøystein, Nils Åge; Lillehaug, Johan R..
Human Protein N-terminal Acetyltransferase hNaa50p (hNAT5/hSAN) Follows Ordered Sequential Catalytic Mechanism (combined kinetic and NMR study). Journal of Biological Chemistry 2012 ;Volum 287.(13) s. 10081-10088
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9 Ve, Thomas; Mathisen, Karina; Helland, Ronny; Karlsen, Odd Andre; Fjellbirkeland, Anne; Røhr, Åsmund Kjendseth; Andersson, K. Kristoffer; Pedersen, Rolf B.; Lillehaug, Johan R.; Jensen, Harald B.
The Methylococcus capsulatus (Bath) Secreted Protein, MopE*, Binds Both Reduced and Oxidized Copper. PLOS ONE 2012 ;Volum 7.(8) s. -
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2011
10 Hole, Kristine; Van Damme, Petra; Dalva, Monica; Aksnes, Henriette; Glomnes, Nina; Varhaug, Jan Erik; Lillehaug, Johan R.; Gevaert, Kris; Arnesen, Thomas.
The human N-Alpha-Acetyltransferase 40 (hNaa40p/hNatD) is conserved from yeast and N-terminally acetylates histones H2A and H4. PLOS ONE 2011 ;Volum 6.(9) s. -
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11 Berge, Elisabet Ognedal; Knappskog, Stian; Lillehaug, Johan R.; Lønning, Per Eystein.
Alterations of the retinoblastoma gene in metastatic breast cancer. Clinical and Experimental Metastasis 2011 ;Volum 28.(3) s. 319-326
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12 Chrisanthar, Ranjan; Knappskog, Stian; Løkkevik, Erik; Anker, Gun Birgitta; Østenstad, Bjørn; Lundgren, Steinar; Risberg, Terje; Mjaaland, Ingvil; Skjønsberg, Gudbrand; Aas, Turid; Schlichting, Ellen; Fjøsne, Hans Erikssønn; Nysted, Arne; Lillehaug, Johan R.; Lønning, Per Eystein.
Predictive and Prognostic Impact of TP53 Mutations and MDM2 Promoter Genotype in Primary Breast Cancer Patients Treated with Epirubicin or Paclitaxel. PLOS ONE 2011 ;Volum 6.(4) s. -
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13 Knappskog, Stian; Bjørnslett, Merete Pauline; Myklebust, Line Merethe; Huijts, Petra E.A.; Vreeswijk, Maaike P.; Edvardsen, Hege; Guo, Yongli; Zhang, Xuemei; Yang, Ming; Ylisaukko-oja, Sanna K.; Alhopuro, Pia; Arola, Johanna; Tollenaar, Rob A.E.M.; van Asperen, Christi J; Seynaeve, Caroline; Staalesen, Vidar; Chrisanthar, Ranjan; Løkkevik, Erik; Salvesen, Helga Birgitte; Evans, D. Gareth; Newman, William G.; Lin, Dongxin; Aaltonen, Lauri; Børresen-Dale, Anne-Lise; Tell, Grethe S; Stoltenberg, Camilla; Romundstad, Pål Richard; Hveem, Kristian; Lillehaug, Johan R.; Vatten, Lars Johan; Devilee, Peter; Dørum, Anne; Lønning, Per Eystein.
The MDM2 Promoter SNP285C/309G Haplotype Diminishes Sp1 Transcription Factor Binding and Reduces Risk for Breast and Ovarian Cancer in Caucasians. Cancer Cell 2011 ;Volum 19.(2) s. 273-282
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14 Knappskog, Stian; Myklebust, Line Merethe; Busch, Christian; Aloysius, Thomas Aquinas; Varhaug, Jan Erik; Lønning, Per Eystein; Lillehaug, Johan R.; Pendino, Frederic.
RINF (CXXC5) is overexpressed in solid tumors and is an unfavorable prognostic factor in breast cancer(dagger). Annals of Oncology 2011 ;Volum 22.(10) s. 2208-2215
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15 Myklebust, Line Merethe; Akslen, Lars A.; Varhaug, Jan Erik; Lillehaug, Johan R..
Receptor for Activated Protein C Kinase 1 (RACK1) Is Overexpressed in Papillary Thyroid Carcinoma. Thyroid 2011 ;Volum 21.(11) s. 1217-1225
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16 Rope, AF; Wang, K; Evjenth, R; Xing, JC; Johnston, JJ; Swensen, JJ; Johnson, WE; Moore, B; Huff, CD; Bird, LM; Carey, JC; Opitz, JM; Stevens, CA; Schank, C; Fain, HD; Robison, R; Dalley, B; Chin, S; South, ST; Pysher, TJ; Jorde, LB; Hakonarson, H; Lillehaug, Johan R.; Biesecker, LG; Yandell, M; Arnesen, Thomas; Lyon, GJ.
Massively parallel sequencing identifies a previously unrecognized X-linked disorder resulting in lethality in male infants owing to amino-terminal acetyltransferase deficiency. Genome Biology 2011 ;Volum 12. s. 11-11
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17 Rope, AF; Wang, K; Evjenth, Rune Henrik; Xing, JC; Johnston, JJ; Swensen, JJ; Johnson, WE; Moore, B; Huff, CD; Bird, LM; Carey, JC; Opitz, JM; Stevens, CA; Jiang, T; Schank, C; Fain, HD; Robison, R; Dalley, B; Chin, S; South, ST; Pysher, TJ; Jorde, LB; Hakonarson, H; Lillehaug, Johan R.; Biesecker, LG; Yandell, M; Arnesen, Thomas; Lyon, GJ.
Using VAAST to Identify an X-Linked Disorder Resulting in Lethality in Male Infants Due to N-Terminal Acetyltransferase Deficiency. American Journal of Human Genetics 2011 ;Volum 89.(1) s. 28-43
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18 Rope, Alan; Wang, Kai; Evjenth, Rune Henrik; Xing, Jinchuan; Johnston, Jennifer; Swensen, Jeffrey; Johnson, W. Evan; Moore, Barry; Huff, Chad D.; Bird, Lynne M.; Carey, John C.; Opitz, John M.; Stevens, Cathy A.; Schank, Crista; Fain, Heidi Deborah; Robison, Reid; Dalley, Brian; Chin, Steven; South, Sarah T.; Pysher, Theodore; Jorde, Lynn B.; Hakonarson, Hakon; Lillehaug, Johan R.; Biesecker, Leslie B.; Yandell, Mark; Arnesen, Thomas; Lyon, Gholson J.
Massively parallel sequencing and clinical characterization of a novel disorder caused by protein N-terminal acetyltransferase deficiency. CSHL 2011 -The Biology of Genomes; 2011-05-10 - 2011-05-14
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19 Van Damme, P; Evjenth, Rune Henrik; Foyn, Håvard; Demeyer, K; De Bock, PJ; Lillehaug, Johan R.; Vandekerckhove, J; Arnesen, Thomas; Gevaert, K.
Proteome-derived Peptide Libraries Allow Detailed Analysis of the Substrate Specificities of N-alpha-acetyltransferases and Point to hNaa10p as the Post-translational Actin N-alpha-acetyltransferase. Molecular & Cellular Proteomics 2011 ;Volum 10.(5) s. -
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2010
20 Arnesen, Thomas; Gromyko, Darina; Evjenth, Rune Henrik; Hole, Kristine; Thompson, Paul R.; Varhaug, Jan Erik; Lillehaug, Johan R..
The protein N-terminal acetyltransferase NatA: A novel target for cancer chemotherapy?. 35th FEBS Congress 2010; 2010-06-26 - 2010-07-01
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21 Arnesen, Thomas; Gromyko, Darina; Evjenth, Rune Henrik; Hole, Kristine; Thompson, Paul R.; Varhaug, Jan Erik; Lillehaug, Johan R..
The protein N-terminal acetyltransferase NatA: A novel target for thyroid cancer chemotherapy?. ESES 4th Biennial Congress 2010; 2010-05-13 - 2010-05-15
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22 Arnesen, Thomas; Gromyko, Darina; Evjenth, Rune Henrik; Jones, Justin; Hole, Kristine; Flick, Heather; Thompson, Paul R.; Varhaug, Jan Erik; Lillehaug, Johan R..
The protein N-terminal acetyltransferase NatA: A novel target for thyroid cancer chemotherapy?. 14th International Thyroid Congress; 2010-09-11 - 2010-09-16
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23 Arnesen, Thomas; Gromyko, Darina; Varhaug, Jan Erik; Lillehaug, Johan R..
The protein N-terminal acetyltransferase NatA: A novel target for cancer chemotherapy?. The FEBS Journal 2010 ;Volum 277. s. 175-175
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24 Berge, Elisabet Ognedal; Knappskog, Stian; Geisler, Stephanie; Staalesen, Vidar; Pacal, Marec; Børresen-Dale, Anne-Lise; Puntervoll, Pål; Lillehaug, Johan R.; Lønning, Per Eystein.
Identification and characterization of retinoblastoma gene mutations disturbing apoptosis in human breast cancers. Molecular Cancer 2010 ;Volum 9. s. -
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25 Berge, Elisabet Ognedal; Staalesen, Vidar; Straume, Anne Hege; Lillehaug, Johan R.; Lønning, Per Eystein.
Chk2 splice variants express a dominant-negative effect on the wild-type Chk2 kinase activity. BBA - Molecular Cell Research 2010 ;Volum 1803.(3) s. 386-395
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26 Busch, Christian; Geisler, Jürgen; Knappskog, Stian; Lillehaug, Johan R.; Lønning, Per Eystein.
Alterations in the p53 Pathway and p16INK4a Expression Predict Overall Survival in Metastatic Melanoma Patients Treated with Dacarbazine. Journal of Investigative Dermatology 2010 ;Volum 130.(10) s. 2514-2516
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27 Busch, Christian; Geisler, Jürgen; Lillehaug, Johan R.; Lønning, Per Eystein.
MGMT expression levels predict disease stabilisation, progression-free and overall survival in patients with advanced melanomas treated with DTIC. European Journal of Cancer 2010 ;Volum 46.(11) s. 2127-2133
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28 Evjenth, Rune Henrik; Hole, Kristine; Karlsen, Odd Andre; Ziegler, Mathias; Arnesen, Thomas; Lillehaug, Johan R..
Human Naa50p (Nat5/San) displays both protein N-alpha- and N-epsilon-Acetyltransferase activity. The FEBS Journal 2010 ;Volum 277. s. 182-182
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29 Evjenth, Rune Henrik; Hole, Kristine; Ziegler, Mathias; Lillehaug, Johan R..
Application of reverse-phase HPLC to quantify oligopeptide acetylation eliminates interference from unspecific acetyl CoA hydrolysis. The FEBS Journal 2010 ;Volum 277. s. 265-266
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30 Gromyko, Darina; Arnesen, Thomas; Ryningen, Anita; Varhaug, Jan Erik; Lillehaug, Johan R..
Depletion of the human N-alpha-terminal acetyltransferase A induces p53-dependent apoptosis and p53-independent growth inhibition. International Journal of Cancer 2010 ;Volum 127.(12) s. 2777-2789
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31 Hole, Kristine; Evjenth, Rune Henrik; Karlsen, Odd Andre; Ziegler, Mathias; Arnesen, Thomas; Lillehaug, Johan R..
Human Naa50p (Nat5/San) Displays Both Protein Na-and Ne-Acetyltransferase activity. FEBS Congress; 2010-06-26 - 2010-07-01
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32 Hole, Kristine; Karlsen, Odd Andre; Ziegler, Mathias; Arnesen, Thomas; Lillehaug, Johan R.; Ryningen, Anita; Vandekerckhove, Joel; Gevaert, Kris; Anderson, D.
The chaperone-like protein HYPK acts together with NatA in cotranslational N-terminal acetylation and prevention of Huntingtin aggregation. The FEBS Journal 2010 ;Volum 277. s. 185-185
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33 Jönsson, Göran; Busch, Christian; Knappskog, Stian; Geisler, Jürgen; Miletic, Hrvoje; Ringnér, Markus; Lillehaug, Johan R.; Borg, Åke; Lønning, Per Eystein.
Gene Expression Profiling-Based Identification of Molecular Subtypes in Stage IV Melanomas with Different Clinical Outcome. Clinical Cancer Research 2010 ;Volum 16.(13) s. 3356-3367
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2009
34 Arnesen, Thomas; Gromyko, Darina; Kagabo, Diane; Betts, Matthew James; Starheim, Kristian Kobbenes; Varhaug, Jan Erik; Anderson, Dave; Lillehaug, Johan.
A novel human NatA N-alpha-terminal acetyltransferase complex: hNaa16p-hNaa10p (hNat2-hArd1). BMC Biochemistry 2009 ;Volum 10. s. -
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35 Arnesen, Thomas; Van Damme, Petra; Polevoda, Bogdan; Helsens, Kenny; Evjenth, Rune Henrik; Colaert, Niklaas; Varhaug, Jan Erik; Vandekerckhove, Joel; Lillehaug, Johan; Sherman, Fred; Gevaert, Kris.
Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans. Proceedings of the National Academy of Sciences of the United States of America 2009 ;Volum 106.(20) s. 8157-8162
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36 Bruland, Ove; Fluge, Øystein; Akslen, Lars A.; Eiken, Hans Geir; Lillehaug, Johan R.; Varhaug, Jan Erik; Knappskog, Per Morten.
Inverse correlation between PDGFC expression and lymphocyte infiltration in human papillary thyroid carcinomas. BMC Cancer 2009 ;Volum 9. s. 425-
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37 Evjenth, Rune Henrik; Hole, Kristine; Karlsen, Odd Andre; Ziegler, Mathias; Arnesen, Thomas; Lillehaug, Johan R..
Human Naa50p (Nat5/San) Displays Both Protein N-alpha- and N-epsilon-Acetyltransferase Activity. Journal of Biological Chemistry 2009 ;Volum 284.(45) s. 31122-31129
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38 Målen, Hiwa; Lillehaug, Johan R.; Arnesen, Thomas.
The protein Nα-terminal acetyltransferase hNaa10p (hArd1) is phosphorylated in HEK293 cells. BMC Research Notes 2009 ;Volum 2.
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39 Pendino, Frederic; Nguyen, Eric; Jonassen, Inge; Dysvik, Bjarte; Azouz, Abdulkader; Lanotte, Michel; Ségal-Bendirdjian, Evelyne; Lillehaug, Johan.
Functional involvement of RINF, retinoid-inducible nuclear factor (CXXC5), in normal and tumoral human myelopoiesis. Blood 2009 ;Volum 113.(14) s. 3172-3181
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40 Starheim, Kristian Kobbenes; Arnesen, Thomas; Gromyko, Darina; Ryningen, Anita; Evjenth, Rune Henrik; Varhaug, Jan Erik; Lillehaug, Johan.
Identification and characterization of the human N-acetyltransferase complexes hNatB and hNatC. Experimental Biology 2009 Annual Conference; 2009-04-18
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41 Starheim, Kristian Kobbenes; Arnesen, Thomas; Gromyko, Darina; Ryningen, Anita; Evjenth, Rune Henrik; Varhaug, Jan Erik; Lillehaug, Johan.
N-terminal protein acetylation in humans. Kontaktmøte; 2009-01-29 - 2009-02-01
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42 Starheim, Kristian Kobbenes; Gromyko, Darina; Evjenth, Rune Henrik; Ryningen, Anita; Varhaug, Jan Erik; Lillehaug, Johan; Arnesen, Thomas.
Knockdown of the human N-alpha-acetyltransferace complex C (hNatC) leads to p53-dependent apoptosis and aberrant hArl8b localization. Molecular and Cellular Biology 2009 ;Volum 29.(13) s. 3569-3581
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43 Starheim, Kristian Kobbenes; Gromyko, Darina; Evjenth, Rune Henrik; Ryningen, Anita; Varhaug, Jan Erik; Lillehaug, Johan; Arnesen, Thomas.
The human N-acetyltransferase complex C (hNatC). Young scientists retreat; 2009-09-04
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44 Svensen, Øyvind; Raae, Arnt Johan; Lillehaug, Johan; Frette, Øyvind.
Investigations of RACK1 by use of FLIM measurements of transfected fluorescent proteins. 6th Annual Advanced Imaging Methods Workshop; 2009-01-21 - 2009-01-23
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2008
45 Arnesen, Thomas; Thompson, Paul R.; Varhaug, Jan Erik; Lillehaug, Johan.
The Protein Acetyltransferase ARD1: A Novel Cancer Drug Target?. Current Cancer Drug Targets 2008 ;Volum 8.(7) s. 545-553
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46 Arnesen, Thomas; Van Damme, Petra; Polevoda, Bogdan; Helsens, Kenny; Evjenth, Rune Henrik; Varhaug, Jan Erik; Vandekerckhove, Joel; Lillehaug, Johan; Sherman, Fred; Gevaert, Kris.
Protein N-α-acetylation analyzed by N-terminal COFRADIC. HUPO 2008 - 7th Annual World Congress of the Human Proteome Organization; 2008-08-18 - 2008-08-20
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47 Chrisanthar, Ranjan; Knappskog, Stian; Løkkevik, Erik; Anker, Gun Birgitta; Østenstad, Bjørn; Lundgren, Steinar; Berge, Elisabet Ognedal; Risberg, Terje; Mjaaland, Ingvil; Mæhle, Lovise Olaug; Engebretsen, Lars Fredri; Lillehaug, Johan; Lønning, Per Eystein.
CHEK2 mutations affecting kinase activity together with mutations in TP53 indicate a functional pathway associated with resistance to epirubicin in primary breast cancer. PLOS ONE 2008 ;Volum 3:e0003062.(8) s. -
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48 Helland, Ronny; Fjellbirkeland, Anne; Karlsen, Odd-Arne; Lillehaug, Johan Richard; Jensen, Harald; Ve, Thomas.
An oxidized tryptophan facilitates copper binding in Methylococcus capsulatus-secreted protein MopE. Journal of Biological Chemistry 2008 ;Volum 283.(20) s. 13897-13904
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49 Karlsen, Odd Andre; Lillehaug, Johan; Jensen, Harald B.
The presence of multiple c-type cytochromes at the surface of the methanotrophic bacterium Methylococcus capsulatus (Bath) is regulated by copper. Molecular Microbiology 2008 ;Volum 70.(1) s. 15-26
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50 Myklebust, Line Merethe; Bjørndal, Bodil; Rosendal, Ken Roger; Myromslien, Frøydis Deinboll; Lorens, James; Nolan, Gary; Bruland, Ove; Lillehaug, Johan.
The scaffold protein RACK1 regulates Ki-Ras-mediated signaling and morphological transformation of NIH 3T3 cells. The FEBS Journal 2008 ;Volum 275. Suppl. 1 s. 315-315
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