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2024
1 Vogt, Elinor Margrethe; Bratland, Eirik; Berland, Siren; Berentsen, Ragnhild Drage; Lund, Agnethe; Björnsdottir, Sigridur; Husebye, Eystein Sverre; Øksnes, Marianne.
Improving diagnostic precision in primary ovarian insufficiency using comprehensive genetic and autoantibody testing. Human Reproduction 2024 ;Volum 39.(1) s. 177-189
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2023
2 Oftedal, Bergithe Eikeland; Berger, Amund Holte; Bruserud, Øyvind; Goldfarb, Yael; Sulen, André; Breivik, Lars Ertesvåg; Hellesen, Richard Alexander Svortevik; Haffner-Krausz, Rebecca; Knappskog, Per Morten; Johansson, Stefan; Wolff, Anette Susanne Bøe; Bratland, Eirik; Abramson, Jakub; Husebye, Eystein Sverre.
A partial form of AIRE deficiency underlies a mild form of autoimmune polyendocrine syndrome type 1. Journal of Clinical Investigation 2023 ;Volum 133.(21) s. -
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3 Tkemaladze, Tinatin; Bratland, Eirik; Bregvadze, Kakha; Shatirishvili, Teona; Tatishvili, Nino; Abzianidze, Elene; Houge, Gunnar Douzgos; Houge, Sofia Douzgou.
MSMO1 deficiency: a potentially partially treatable, ultrarare neurodevelopmental disorder with psoriasiform dermatitis, alopecia and polydactyly. Clinical Dysmorphology 2023 ;Volum 32.(3) s. 97-105
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2022
4 Sjøgren, Thea; Bratland, Eirik; Røyrvik, Ellen Christine; Grytaas, Marianne; Benneche, Andreas; Knappskog, Per Morten; Kämpe, Olle; Oftedal, Bergithe Eikeland; Husebye, Eystein Sverre; Wolff, Anette Susanne Bøe.
Screening patients with autoimmune endocrine disorders for cytokine autoantibodies reveals monogenic immune deficiencies. Journal of Autoimmunity 2022 ;Volum 133:102917. s. 1-?
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2021
5 Berger, Amund Holte; Bratland, Eirik; Sjøgren, Thea; Heimli, Marte; Tyssedal, Torgeir; Bruserud, Øyvind; Johansson, Stefan; Husebye, Eystein Sverre; Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe.
Transcriptional changes in regulatory T cells from patients with autoimmune polyendocrine syndrome type 1 suggest functional impairment of lipid metabolism and gut homing. Frontiers in Immunology 2021 ;Volum 12:722860. s. 1-12
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6 Cappuccio, Gerarda; Ceccatelli Berti, Camilla; Baruffini, Enrico; Sullivan, Jennifer; Shashi, Vandana; Jewett, Tamison; Stamper, Tara; Maitz, Silvia; Canonico, Francesco; Revah-Politi, Anya; Kupchik, Gabriel S.; Anyane-Yeboa, Kwame; Aggarwal, Vimla S.; Benneche, Andreas; Bratland, Eirik; Berland, Siren; D'Arco, Felice; Alves, Cesar A.; Vanderver, Adeline; Longo, Daniela; Bertini, Enrico; Torella, Annalaura; Nigro, Vincenzo; D'Amico, Alessandra; van der Knaap, Marjo S.; Goffrini, Paola; Brunetti-Pierri, N.
Bi-allelic KARS1 pathogenic variants affecting functions of cytosolic and mitochondrial isoforms are associated with a progressive and multisystem disease. Human Mutation 2021 ;Volum 42.(6) s. 745-761
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7 Corder, Megan L.; Berland, Siren; Førsvoll, Jostein Andersen; Banerjee, Indraneel; Murray, Phil; Bratland, Eirik; Gokhale, David; Houge, Gunnar Douzgos; Houge, Sofia Douzgou.
Truncating and zinc-finger variants in GLI2 are associated with hypopituitarism. American Journal of Medical Genetics. Part A 2021 s. 1-10
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8 Eriksson, Daniel; Røyrvik, Ellen Christine; Aranda-Guillen, Maribel; Berger, Amund Holte; Landegren, Nils; Alvarez, Haydee Maribel Artaza; Hallgren, Åsa; Grytaas, Marianne; Strøm, Sara; Bratland, Eirik; Botusan, Ileana; Oftedal, Bergithe Eikeland; Breivik, Lars Ertesvåg; Vaudel, Marc; Helgeland, Øyvind; Falorni, Alberto; Jørgensen, Anders Palmstrøm; Hulting, Anna-Lena; Svartberg, Johan; Ekwall, Olov; Fougner, Kristian J; Wahlberg, Jeanette; Nedrebø, Bjørn Gunnar; Dahlqvist, Per; Knappskog, Per Morten; Wolff, Anette Susanne Bøe; Bensing, Sophie; Johansson, Stefan; Kämpe, Olof; Husebye, Eystein Sverre.
GWAS for autoimmune Addison's disease identifies multiple risk loci and highlights AIRE in disease susceptibility. Nature Communications 2021 ;Volum 12:959. s. 1-14
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9 Goldfarb, Yael; Givony, Tal; Kadouri, Noam; Dobeš, Jan; Peligero-Cruz, Cristina; Zalayat, Itay; Damari, Golda; Dassa, Bareket; Ben-Dor, Shifra; Gruper, Yael; Oftedal, Bergithe Eikeland; Bratland, Eirik; Erichsen, Martina Moter; Berger, Amund Holte; Avin, Ayelet; Nevo, Shir; Haljasorg, Uku; Kuperman, Yael; Ulman, Adi; Haffner-Krausz, Rebecca; Porat, Ziv; Atasoy, Ulus; Leshkowitz, Dena; Husebye, Eystein Sverre; Abramson, Jakub.
Mechanistic dissection of dominant AIRE mutations in mouse models reveals AIRE autoregulation. Journal of Experimental Medicine (JEM) 2021 ;Volum 218.(11) s. -
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10 Hellesen, Alexander; Aslaksen, Sigrid; Breivik, Lars Ertesvåg; Røyrvik, Ellen Christine; Bruserud, Øyvind; Edvardsen, Kine Susann Waade; Brokstad, Karl Albert; Wolff, Anette Susanne Bøe; Husebye, Eystein Sverre; Bratland, Eirik.
21-Hydroxylase-Specific CD8+ T Cells in Autoimmune Addison’s Disease Are Restricted by HLA-A2 and HLA-C7 Molecules. Frontiers in Immunology 2021 ;Volum 12. s. -
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11 Sævik, Åse Bjorvatn; Wolff, Anette Susanne Bøe; Björnsdottir, Sigridur; Simunkova, Katerina; Hynne, Martha Schei; Dolan, David William Peter; Bratland, Eirik; Knappskog, Per M; Methlie, Paal; Carlsen, Siri; Isaksson, Magnus; Bensing, Sophie; Kämpe, Olle; Husebye, Eystein S; Løvås, Kristian; Øksnes, Marianne.
Potential Transcriptional Biomarkers to Guide Glucocorticoid Replacement in Autoimmune Addison's Disease. Journal of the Endocrine Society (JES) 2021 ;Volum 5.(3) s. 1-10
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12 Taule-Sivertsen, Peter; Bruland, Ove; Håvik, Aril Løge; Bratland, Eirik; Lund-Johansen, Morten; Knappskog, Per Morten.
The SH3PXD2A-HTRA1 fusion transcript is extremely rare in Norwegian sporadic vestibular schwannoma patients. Journal of Neuro-Oncology 2021 ;Volum 154. s. 35-40
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13 Wolff, Anette Susanne Bøe; Breivik, Lars Ertesvåg; Hufthammer, Karl Ove; Grytaas, Marianne; Bratland, Eirik; Husebye, Eystein Sverre; Oftedal, Bergithe Eikeland.
The natural history of 21-hydroxylase autoantibodies in autoimmune Addison’s disease. European Journal of Endocrinology (EJE) 2021 ;Volum 184.(4) s. 607-615
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2020
14 Rahman, Mohummad Aminur; Brekke, Jorunn; Arnesen, Victoria Smith; Hannisdal, Marianne Hjellvik; Gras Navarro, Andrea; Waha, Andreas; Herfindal, Lars; Rygh, Cecilie Brekke; Bratland, Eirik; Brandal, Petter; Haász, Judit; Oltedal, Leif; Miletic, Hrvoje; Lundervold, Arvid; Lie, Stein Atle; Goplen, Dorota; Enger, Martha Chekenya.
Sequential bortezomib and temozolomide treatment promotes immunological responses in glioblastoma patients with positive clinical outcomes: A phase 1B study. Immunity,Inflammation and Disease 2020 ;Volum 8.(3) s. 342-359
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2019
15 Aslaksen, Sigrid; Methlie, Paal; Vigeland, Magnus Dehli; Jøssang, Dag Eirik; Wolff, Anette Susanne Bøe; Sheng, Ying; Oftedal, Bergithe Eikeland; Skinningsrud, Beate; Undlien, Dag Erik; Selmer, Kaja Kristine; Husebye, Eystein Sverre; Bratland, Eirik.
Coexistence of congenital adrenal hyperplasia and autoimmune Addison's disease. Frontiers in Endocrinology 2019 ;Volum 10:648. s. 1-5
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16 Aslaksen, Sigrid; Wolff, Anette Susanne Bøe; Vigeland, Magnus Dehli; Breivik, Lars Ertesvåg; Sheng, Ying; Oftedal, Bergithe Eikeland; Skinningsrud, Beate; Undlien, Dag Erik; Selmer, Kaja Kristine; Husebye, Eystein Sverre; Bratland, Eirik.
Identification and characterization of rare Toll-like receptor 3 variants in patients with autoimmune Addison’s disease. Journal of translational autoimmunity 2019 ;Volum 1.
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2018
17 Hellesen, Alexander; Bratland, Eirik.
The potential role for infections in the pathogenesis of autoimmune Addison?s disease. Clinical and Experimental Immunology 2018 s. 1-12
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18 Hellesen, Alexander; Bratland, Eirik; Husebye, Eystein Sverre.
Autoimmune Addison's disease – An update on pathogenesis. Annales d'Endocrinologie 2018 ;Volum 79.(3) s. 157-163
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19 Hjøllo, Torunn; Bratland, Eirik; Steinsland, Hans; Radunovic, Matej; Langeland, Nina; Hanevik, Kurt.
Longitudinal cohort study of serum antibody responses towards Giardia lamblia variant-specific surface proteins in a non-endemic area. Experimental parasitology 2018 ;Volum 191. s. 66-72
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2017
20 Bahador, Marzieh; Gras Navarro, Andrea; Rahman, Mohummad Aminur; Dominguez Valentin, Mev; Sarowar, Shahin; Ulvestad, Elling; Njølstad, Gro; Lie, Stein Atle; Kristoffersen, Einar Klæboe; Bratland, Eirik; Enger, Martha Chekenya.
Increased infiltration and tolerised antigen-specific CD8+ TEM cells in tumor but not peripheral blood have no impact on survival of HCMV+ glioblastoma patients. Oncoimmunology 2017 ;Volum 6.(8:e1336272) s. 1-15
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21 Bruserud, Øyvind; Bratland, Eirik; Hellesen, Alexander; Delaleu, Nicolas; Reikvam, Håkon; Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe.
Altered immune activation and IL-23 signaling in response to Candida albicans in autoimmune polyendocrine syndrome type 1. Frontiers in Immunology 2017 ;Volum 8:1074. s. 1-10
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2016
22 Bruserud, Øyvind; Oftedal, Bergithe Eikeland; Landegren, Nils; Erichsen, Martina Moter; Bratland, Eirik; Lima, Kari; Jørgensen, Anders Palmstrøm; Myhre, Anne Grethe; Svartberg, Johan; Fougner, Kristian J; Bakke, Åsne; Nedrebø, Bjørn Gunnar; Mella, Bjarne; Breivik, Lars Ertesvåg; Viken, Marte K; Knappskog, Per; Cuida Marthinussen, Ileana Mihaela; Løvås, Kristian; Kämpe, Olle; Wolff, Anette Susanne Bøe; Husebye, Eystein Sverre.
A longitudinal follow-up of autoimmune polyendocrine syndrome type 1. Journal of Clinical Endocrinology and Metabolism (JCEM) 2016 ;Volum 101.(8) s. 2975-2983
UiO AHUS UiB HAUKELAND OUS UiT STO SUS OSTFSYK UNN HELSEFONNA Untitled
 
23 Edvardsen, Kine Susann Waade; Hellesen, Alexander; Husebye, Eystein Sverre; Bratland, Eirik.
Analysis of cellular and humoral immune responses against cytomegalovirus in patients with autoimmune Addison's disease. Journal of Translational Medicine 2016 ;Volum 14:68.
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24 Hellesen, Alexander.
Immuno-endocrine interactions in autoimmune Addison's disease. : University of Bergen 2016 (ISBN 978-82-308-3368-1)
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25 Hetemäki, Iivo; Jarva, Hanna; Kluger, Nicolas; Baldauf, Hanna-Mari; Laakso, Sini; Bratland, Eirik; Husebye, Eystein Sverre; Kisand, Kai; Ranki, Annamari; Peterson, Pärt; Arstila, T.Petteri.
Anticommensal responses are associated with regulatory T cell defect in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients. Journal of Immunology 2016 ;Volum 196.(7) s. 2955-2964
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2015
26 Astor, Marianne; Løvås, Kristian; Wolff, Anette Susanne Bøe; Nedrebø, Bjørn Gunnar; Bratland, Eirik; Steen-Johnsen, Jon; Husebye, Eystein Sverre.
Hypomagnesemia and functional hypoparathyroidism due to novel mutations in the Mg-channel TRPM6. Endocrine Connections 2015 ;Volum 4. s. 215-222
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27 Edvardsen, Kine Susann Waade; Bjånesøy, Trine Elholm; Hellesen, Alexander; Breivik, Lars Ertesvåg; Bakke, Marit; Husebye, Eystein Sverre; Bratland, Eirik.
Peripheral blood cells from patients with autoimmune Addison's disease poorly respond to interferons in vitro, despite elevated serum levels of interferon-inducible chemokines. Journal of Interferon and Cytokine Research 2015 ;Volum 35.(10) s. 759-770
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28 Edvardsen, Kine Susann Waade.
Autoimmunity and viral immunity in Addison’s disease. : University of Bergen 2015 (ISBN 978-82-308-3441-1)
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29 Fichna, Marta; Zurawek, Magdalena; Bratland, Eirik; Husebye, Eystein Sverre; Kasperlik-Zaluska, Anna; Czarnocka, Barbara; Januszkiewicz-Lewandowska, Danuta; Nowak, Jerzy.
Interleukin-2 and subunit alpha of its soluble receptor in autoimmune Addison's disease - An association study and expression analysis. Autoimmunity 2015 ;Volum 48.(2) s. 100-107
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30 Oftedal, Bergithe Eikeland; Hellesen, Alexander; Erichsen, Martina Moter; Bratland, Eirik; Vardi, Ayelet; Perheentupa, Jaakko; Kemp, E. Helen; Fiskerstrand, Torunn; Viken, Marte K; Weetman, Anthony P.; Fleishman, Sarel J.; Banka, Siddharth; Newman, William G.; Sewell, William A. Carrock; Sozaeva, Leila S.; Zayats, Tetyana; Haugarvoll, Kristoffer; Orlova, Elizaveta M.; Haavik, Jan; Johansson, Stefan; Knappskog, Per; Løvås, Kristian; Wolff, Anette Susanne Bøe; Abramson, Jakub; Husebye, Eystein Sverre.
Dominant mutations in the autoimmune regulator AIRE are associated with common organ-specific autoimmune diseases. Immunity 2015 ;Volum 42.(6) s. 1185-1196
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2014
31 Bjånesøy, Trine Elholm; Kulle, Bettina; Bratland, Eirik; Reiner, Andrew Henry; Islam, Shahinul; Husebye, Eystein Sverre; Bakke, Marit.
Altered DNA methylation profile in Norwegian patients with Autoimmune Addison's Disease. Molecular Immunology 2014 ;Volum 59.(2) s. 208-216
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32 Breivik, Lars Ertesvåg; Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe; Bratland, Eirik; Orlova, Elizaveta M.; Husebye, Eystein Sverre.
A novel cell-based assay for measuring neutralizing autoantibodies against type I interferons in patients with autoimmune polyendocrine syndrome type 1. Clinical Immunology 2014 ;Volum 153.(1) s. 220-227
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33 Brønstad, Ingeborg; Breivik, Lars Ertesvåg; Methlie, Paal; Wolff, Anette Susanne Bøe; Bratland, Eirik; Nermoen, Ingrid; Løvås, Kristian; Husebye, Eystein Sverre.
Functional studies of novel CYP21A2 mutations detected in Norwegian patients with congenital adrenal hyperplasia. Endocrine Connections 2014 ;Volum 15.(3) Suppl. 2 s. 67-74
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34 Brønstad, Ingeborg; Skinningsrud, Beate; Bratland, Eirik; Løvås, Kristian; Undlien, Dag Erik; Husebye, Eystein Sverre; Wolff, Anette Susanne Bøe.
CYP21A2 polymorphisms in patients with autoimmune Addison's disease, and linkage disequilibrium to HLA risk alleles. European Journal of Endocrinology (EJE) 2014 ;Volum 171.(6) s. 743-750
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35 Dawoodji, Amina; Chen, Ji-Li; Shepherd, Dawn; Dalin, Frida; Tarlton, Andrea; Alimohammadi, Mohammad; Penna-Martinez, Marissa; Meyer, Gesine; Mitchell, Anna L.; Gan, Earn H.; Bratland, Eirik; Bensing, Sophie; Husebye, Eystein Sverre; Pearce, Simon H.; Badenhoop, Klaus; Kämpe, Olle; Cerundolo, Vincenzo.
High frequency of cytolytic 21-hydroxylase-specific CD8+ T cells in autoimmune Addison's disease patients. Journal of Immunology 2014 ;Volum 193.(5) s. 2118-2126
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36 Hellesen, Richard Alexander; Edvardsen, Kine Susann Waade; Breivik, Lars Ertesvåg; Husebye, Eystein Sverre; Bratland, Eirik.
The effect of types I and III interferons on adrenocortical cells and its possible implications for autoimmune Addison's disease. Clinical and Experimental Immunology 2014 ;Volum 176.(3) s. 351-362
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2013
37 Bratland, Eirik; Hellesen, Alexander; Husebye, Eystein Sverre.
Induction of CXCL10 chemokine in adrenocortical cells by stimulation through toll-like receptor 3. Molecular and Cellular Endocrinology 2013 ;Volum 365.(1) s. 75-83
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38 Bratland, Eirik; Magitta, Ng'weina Francis; Wolff, Anette Susanne Bøe; Ekern, Trude; Knappskog, Per; Kämpe, Olle; Haavik, Jan; Husebye, Eystein Sverre.
Autoantibodies against aromatic amino acid hydroxylases in patients with autoimmune polyendocrine syndrome type 1 target multiple antigenic determinants and reveal regulatory regions crucial for enzymatic activity. Immunobiology 2013 ;Volum 218.(6) s. 899-909
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39 Breivik, Lars Ertesvåg; Oftedal, Bergithe Eikeland; Bratland, Eirik; Wolff, Anette Susanne Bøe; Orlova, Elizaveta; Husebye, Eystein Sverre.
A novel cell-based assay for measuring neutralizing autoantibodies against type I interferons in patients with APS-1. 15th International Congress of Immunology; 2013-08-22 - 2013-08-27
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40 Brønstad, Ingeborg; Skinningsrud, Beate; Wolff, Anette Susanne Bøe; Bratland, Eirik; Løvås, Kristian; Knappskog, Per; Undlien, Dag Erik; Husebye, Eystein Sverre.
Characterisation of the CYP21A2 Gene in Patients with Autoimmune Addison's Disease. Scandinavian Journal of Immunology 2013 ;Volum 77.(4) s. 310-310
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2012
41 Bratland, Eirik; Hellesen, Richard Alexander; Husebye, Eystein Sverre.
Mice deficient for the autoimmune regulator, Aire, display altered T cell responses against 21-hydroxylase, the major autoantigen in autoimmune Addison's disease. Immunology 2012 ;Volum 137. Suppl. 1 s. 542-542
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42 Hellesen, A; Bratland, Eirik; Husebye, Eystein Sverre.
Poly (I:C)-induced CXCL10 production in adrenocortical cells - implications for autoimmune Addison's disease?. Immunology 2012 ;Volum 137. s. 300-301
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43 Hetemaki, I; Jarva, H; Tervo, H.; Bratland, Eirik; Kisand, K; Peterson, P; Arstila, TP.
Increased antibody levels against gut commensals are associated with regulatory T cell defect in patients with APECED. Immunology 2012 ;Volum 137. s. 421-421
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2011
44 Bratland, Eirik; Husebye, Eystein Sverre.
Cellular immunity and immunopathology in autoimmune Addison’s disease. Molecular and Cellular Endocrinology 2011 ;Volum 336.(1-2) s. 180-190
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45 Hellesen, Richard Alexander; Bratland, Eirik; Husebye, Eystein Sverre.
Endogenous Production of CXC Chemokine Ligand 10 (CXCL10) by Adrenocortical Cells and its Implications for Autoimmune Addison's Disease. Scandinavian Journal of Immunology 2011 ;Volum 73.(4) s. 371-371
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2010
46 Bratland, Eirik; Husebye, Eystein Sverre.
The Possible Roles of Interferon-Gamma, CXC Chemokine Ligand 10 (CXCL10) and the CXCR3 Circuit in the Pathogenesis of Autoimmune Addison's Disease. Scandinavian Journal of Immunology 2010 ;Volum 71.(6) s. 479-480
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2009
47 Bratland, Eirik.
Cellular immunity in autoimmune Addison's disease : T cell responses to steroid cytochrome P450 21-hydroxylase. Universitetet i Bergen 2009 (ISBN 978-82-308-0866-5)
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48 Bratland, Eirik; Bredholt, Geir; Mellgren, Gunnar; Knappskog, Per; Mozes, Edna; Husebye, Eystein Sverre.
The purification and application of biologically active recombinant steroid cytochrome P450 21-hydroxylase: The major autoantigen in autoimmune Addison's disease. Journal of Autoimmunity 2009 ;Volum 33.(1) s. 58-67
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49 Bratland, Eirik; Skinningsrud, B; Undlien, Dag Erik; Mozes, Edna; Husebye, Eystein Sverre.
T Cell Responses to Steroid Cytochrome P450 21-Hydroxylase in Patients with Autoimmune Primary Adrenal Insufficiency. Journal of Clinical Endocrinology and Metabolism (JCEM) 2009 ;Volum 94.(12) s. 5117-5124
UiB UiO HAUKELAND OUS Untitled
 
2008
50 Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe; Bratland, Eirik; Kämpe, Olle; Perheentupa, Jaakko; Myhre, Anne Grethe; Meager, Anthony; Purushothaman, Radhika; Ten, Svetlana; Husebye, Eystein Sverre.
Radioimmunoassay for autoantibodies against interferon omega; its use in the diagnosis of autoimmune polyendocrine syndrome type I. Clinical Immunology 2008 ;Volum 129.(1) s. 163-169
UiB HAUKELAND OUS Untitled
 
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