Cristin

2024
1.	Selheim, Frode; Aasebø, Elise; Bruserud, Øystein; Valladares, Maria del Carmen Hernandez. High Mitochondrial Protein Expression as a Potential Predictor of Relapse Risk in Acute Myeloid Leukemia Patients with the Monocytic FAB Subtypes M4 and M5. Cancers 2024 ;Volum 16.(1) s. - UiB HAUKELAND Untitled
2023
2.	Bartaula-Brevik, Sushma; Leitch, Calum; Valladares, Maria del Carmen Hernandez; Aasebø, Elise; Berven, Frode Steingrimsen; Selheim, Frode; Brenner, Annette; Rye, Kristin Paulsen; Hagen, Karen Marie; Reikvam, Håkon; Mc Cormack, Emmet; Bruserud, Øystein; Tvedt, Tor Henrik Anderson. Vacuolar ATPase Is a Possible Therapeutic Target in Acute Myeloid Leukemia: Focus on Patient Heterogeneity and Treatment Toxicity. Journal of Clinical Medicine 2023 ;Volum 12.(17) s. - UiB HAUKELAND Untitled

3.	Carrillo Rodriguez, Paula; Selheim, Frode; Valladares, Maria del Carmen Hernandez. Mass Spectrometry-Based Proteomics Workflows in Cancer Research: The Relevance of Choosing the Right Steps. Cancers 2023 ;Volum 15.(2) s. - UiB Untitled
2022
4.	Sarowar, Shahin; Cirillo, Davide; Játiva, Pablo; Nilsen, Mette Hartmark; Otragane, Sarah-Muheha Anni; Heggdal, Jan Ingemann; Selheim, Frode; Ceña, Valentín; Bjørsvik, Hans-René; Enger, Per Øyvind. The styryl benzoic acid derivative DC10 potentiates radiotherapy by targeting the xCT-glutathione axis. Frontiers in Oncology 2022 ;Volum 12:786739. s. 1-11 UiB HAUKELAND Untitled
2021
5.	Aasebø, Elise; Brenner, Annette; Birkeland, Even; Tvedt, Tor Henrik Anderson; Selheim, Frode; Berven, Frode Steingrimsen; Bruserud, Øystein. The constitutive extracellular protein release by acute myeloid leukemia cells—A proteomic study of patient heterogeneity and its modulation by mesenchymal stromal cells. Cancers 2021 ;Volum 13.(7) s. - UiB HAUKELAND Untitled

6.	Aasebø, Elise; Brenner, Annette; Hernandez-Valladares, Maria; Birkeland, Even; Berven, Frode Steingrimsen; Selheim, Frode; Bruserud, Øystein. Proteomic comparison of bone marrow derived osteoblasts and mesenchymal stem cells. International Journal of Molecular Sciences 2021 ;Volum 22.(11) UiB HAUKELAND Untitled

7.	Aasebø, Elise; Brenner, Annette; Hernandez-Valladares, Maria; Birkeland, Even; Mjaavatten, Olav; Reikvam, Håkon; Selheim, Frode; Berven, Frode Steingrimsen; Bruserud, Øystein. Patient Heterogeneity in Acute Myeloid Leukemia: Leukemic Cell Communication by Release of Soluble Mediators and Its Effects on Mesenchymal Stem Cells. Diseases 2021 ;Volum 9.(74) UiB HAUKELAND Untitled

8.	Aasebø, Elise; Brenner, Annette; Hernandez-Valladares, Maria; Birkeland, Even; Reikvam, Håkon; Selheim, Frode; Berven, Frode Steingrimsen; Bruserud, Øystein. Proteomic Characterization of Spontaneous Stress-Induced In Vitro Apoptosis of Human Acute Myeloid Leukemia Cells; Focus on Patient Heterogeneity and Endoplasmic Reticulum Stress. Hemato 2021 ;Volum 2.(3) s. 607-627 HAUKELAND UiB Untitled

9.	Grønningsæter, Ida Sofie; Reikvam, Håkon; Aasebø, Elise; Bartaula-Brevik, Sushma; Hernandez‐valladares, Maria; Selheim, Frode; Berven, Frode Steingrimsen; Tvedt, Tor Henrik; Bruserud, Øystein; Hatfield, Kimberley Joanne. Effects of the autophagy‐inhibiting agent chloroquine on acute myeloid leukemia cells; characterization of patient heterogeneity. Journal of Personalized Medicine 2021 ;Volum 11.(8) s. 1-23 AHUS UiB HAUKELAND OUS Untitled

10.	Hernandez-Valladares, Maria; Wangen, Rebecca; Aasebø, Elise; Reikvam, Håkon; Berven, Frode Steingrimsen; Selheim, Frode; Bruserud, Øystein. Proteomic studies of primary acute myeloid leukemia cells derived from patients before and during disease-stabilizing treatment based on all-trans retinoic acid and valproic acid. Cancers 2021 ;Volum 13.(9) s. - HAUKELAND UiB Untitled
2020
11.	Aasebø, Elise; Berven, Frode; Bartaula-Brevik, Sushma; Stokowy, Tomasz; Hovland, Randi; Vaudel, Marc; Døskeland, Stein Ove; Mc Cormack, Emmet; Batth, Tanveer S; Olsen, Jesper V; Bruserud, Øystein; Selheim, Frode; Hernandez-Valladares, Maria. Proteome and Phosphoproteome Changes Associated with Prognosis in Acute Myeloid Leukemia. Cancers 2020 ;Volum 12.(3) HAUKELAND UiB Untitled

12.	Aasebø, Elise; Berven, Frode; Hovland, Randi; Doskeland, Stein Ove; Bruserud, Øystein; Selheim, Frode; Hernandez-Valladares, Maria. The progression of acute myeloid leukemia from first diagnosis to chemoresistant relapse: A comparison of proteomic and phosphoproteomic profiles. Cancers 2020 ;Volum 12.(6) s. 1-13 UiB HAUKELAND Untitled

13.	Aasebø, Elise; Birkeland, Even; Selheim, Frode; Berven, Frode; Brenner, Annette; Bruserud, Øystein. The extracellular bone marrow microenvironment — a proteomic comparison of constitutive protein release by in vitro cultured osteoblasts and mesenchymal stem cells. Cancers 2020 ;Volum 13.(1) UiB HAUKELAND Untitled

14.	Hernandez-Valladares, Maria; Aasebø, Elise; Berven, Frode; Selheim, Frode; Bruserud, Øystein. Biological characteristics of aging in human acute myeloid leukemia cells: the possible importance of aldehyde dehydrogenase, the cytoskeleton and altered transcriptional regulation. Aging 2020 ;Volum 12.(24) s. 24734-24777 UiB Untitled

15.	Hernandez-Valladares, Maria; Bruserud, Øystein; Selheim, Frode. The implementation of mass spectrometry-based proteomics workflows in clinical routines of acute myeloid leukemia: Applicability and perspectives. International Journal of Molecular Sciences 2020 ;Volum 21.(18) s. 1-23 UiB Untitled
2019
16.	Aasebø, Elise; Berven, Frode; Bartaula-Brevik, Sushma; Stokowy, Tomasz; Hovland, Randi; Vaudel, Marc; Døskeland, Stein Ove; Mc Cormack, Emmet; Batth, Tanveer S; Olsen, Jesper V; Bruserud, Øystein; Selheim, Frode; Hernandez-Valladares, Maria. Proteome and phosphoproteome changes associated with prognosis in acute myeloid leukemia. bioRxiv 2019 HAUKELAND UiB Untitled

17.	Aasebø, Elise; Hernandez-Valladares, Maria; Selheim, Frode; Berven, Frode; Brenner, Annette; Bruserud, Øystein. Proteomic profiling of primary human acute myeloid leukemia cells does not reflect their constitutive release of soluble mediators. Proteomes 2019 ;Volum 7.(1) s. 1-10 HAUKELAND UiB Untitled

18.	Brenner, Annette; Aasebø, Elise; Hernandez-Valladares, Maria; Selheim, Frode; Berven, Frode; Grønningsæter, Ida Sofie; Bartaula-Brevik, Sushma; Bruserud, Øystein. The capacity of long-term in vitro proliferation of acute myeloid leukemia cells supported only by exogenous cytokines is associated with a patient subset with adverse outcome. Cancers 2019 ;Volum 11:73. s. 1-22 HAUKELAND UiB Untitled

19.	Nepstad, Ina; Hatfield, Kimberley Joanne; Grønningsæter, Ida Sofie; Aasebø, Elise; Hernandez-Valladares, Maria; Hagen, Karen Marie; Rye, Kristin Paulsen; Berven, Frode; Selheim, Frode; Reikvam, Håkon; Bruserud, Øystein. Effects of insulin and pathway inhibitors on the PI3K-Akt-mTOR phosphorylation profile in acute myeloid leukemia cells.. Signal Transduction and Targeted Therapy 2019 HAUKELAND UiB Untitled

20.	Rahman, Mohummad Aminur; Gras Navarro, Andrea; Brekke, Jorunn; Engelsen, Agnete; Bindesbøll, Christian; Sarowar, Shahin; Bahador, Marzieh; Bifulco, Ersilia; Goplen, Dorota; Waha, Andreas; Lie, Stein Atle; Gjertsen, Bjørn Tore; Selheim, Frode; Enger, Per Øyvind; Simonsen, Anne; Enger, Martha Chekenya. Bortezomib administered prior to temozolomide depletes MGMT, chemosensitizes glioblastoma with unmethylated MGMT promoter and prolongs animal survival. British Journal of Cancer 2019 ;Volum 121. s. 545-555 HAUKELAND UiO UiB Untitled

21.	Selheim, Frode. Targeted and Immune-Based Therapies for Acute Myeloid Leukemia: Inflammatory Signaling and Multiple Post-Translational Modifications. Current Medicinal Chemistry 2019 ;Volum 26.(28) s. 5242-5243 UiB Untitled

22.	Selheim, Frode; Aasebø, Elise; Ribas, Catalina; Aragay, Anna M.. An overview on G protein-coupled receptor-induced signal transduction in acute myeloid leukemia. Current Medicinal Chemistry 2019 ;Volum 26.(28) s. 5293-5316 UiB Untitled

23.	Tveitarås, Maria Kathrine; Selheim, Frode; Sortland, Kristina; Salvesen, Gerd Signe; Reed, Rolf K.; Stuhr, Linda Elin Birkhaug. Protein expression profiling of plasma and lungs at different stages of metastatic development in a human triple negative breast cancer xenograft model.. PLOS ONE 2019 ;Volum 14.(5) UiB Untitled

24.	Åsrud, Kathrine Sivertsen; Pedersen, Line; Aesoy, Reidun; Muwonge, Haruna; Aasebø, Elise; Pettersen, Ina Katrine Nitschke; Herfindal, Lars; Dobie, Ross; Jenkins, Stephen; Berge, Rolf Kristian; Henderson, Neil Cowan; Selheim, Frode; Doskeland, Stein Ove; Bakke, Marit. Mice depleted for Exchange Proteins Directly Activated by cAMP (Epac) exhibit irregular liver regeneration in response to partial hepatectomy. Scientific Reports 2019 ;Volum 9:13789. s. 1-17 UiB HAUKELAND Untitled
2018
25.	Wangen, Rebecca; Aasebø, Elise; Trentani, Andrea; Doskeland, Stein Ove; Bruserud, Øystein; Selheim, Frode; Hernandez-Valladares, Maria. Preservation Method and Phosphate Buffered Saline Washing Affect the Acute Myeloid Leukemia Proteome. International Journal of Molecular Sciences 2018 ;Volum 19.(1) s. 1-11 UiB Untitled

26.	Kleppe, Rune; Jonassen, Inge; Doskeland, Stein Ove; Selheim, Frode. Mathematical modelling of nitric oxide/cyclic GMP/cyclic AMP signalling in platelets. International Journal of Molecular Sciences 2018 ;Volum 19.(2) s. 1-21 UiB Untitled

27.	Nepstad, Ina; Hatfield, Kimberley Joanne; Aasebø, Elise; Hernandez-Valladares, Maria; Brenner, Annette; Bartaula-Brevik, Sushma; Berven, Frode; Selheim, Frode; Skavland, Jørn; Gjertsen, Bjørn Tore; Reikvam, Håkon; Bruserud, Øystein. Two acute myeloid leukemia patient subsets are identified based on the constitutive PI3K-Akt-mTOR signaling of their leukemic cells; a functional, proteomic and transcriptomic comparison. Expert opinion on therapeutic targets 2018 ;Volum 22.(7) s. 639-653 UiB HAUKELAND Untitled

28.	Reis, Luiza C.; Ramos-Sanchez, Eduardo Milton; Petitto-Assis, Fabricio; Nerland, Audun Helge; Hernandez-Valladares, Maria; Selheim, Frode; Floeter-Winter, Lucile Maria; Goto, Hiro. Insulin-Like Growth Factor-I as an Effector Element of the Cytokine IL-4 in the Development of a Leishmania major Infection. Mediators of Inflammation 2018 UiB Untitled
2017
29.	Brenner, Annette; Aasebø, Elise; Hernandez-Valladares, Maria; Selheim, Frode; Berven, Frode; Bruserud, Øystein. Rethinking the role of osteopontin in human acute myeloid leukemia. Leukemia and Lymphoma 2017 ;Volum 58.(6) s. 1494-1497 HAUKELAND UiB Untitled

30.	Hernandez-Valladares, Maria; Vaudel, Marc; Selheim, Frode; Berven, Frode; Bruserud, Øystein. Proteogenomics approaches for studying cancer biology and their potential in the identification of acute myeloid leukemia biomarkers. Expert Review of Proteomics 2017 ;Volum 14.(8) s. 649-663 UiB HAUKELAND Untitled

31.	Forthun, Rakel Brendsdal; Aasebø, Elise; Rasinger, Josef Daiel; Bedringaas, Siv Lise; Berven, Frode; Selheim, Frode; Bruserud, Øystein; Gjertsen, Bjørn Tore. Phosphoprotein DIGE profiles reflect blast differentiation, cytogenetic risk stratification, FLT3/NPM1 mutations and therapy response in acute myeloid leukaemia. Journal of Proteomics 2017 ;Volum 173. s. 32-41 UiB HAUKELAND HAVFORSK Untitled

32.	Kopperud, Reidun Kristin; Rygh, Cecilie Brekke; Karlsen, Tine Veronica; Krakstad, Camilla; Kleppe, Rune; Høivik, Erling Andre; Bakke, Marit; Tenstad, Olav; Selheim, Frode; Liden, Åsa; Madsen, Lise; Pavlin, Tina; Taxt, Torfinn; kristiansen, k; Curry, FE; Reed, Rolf K.; Doskeland, Stein Ove. Increased microvascular permeability in mice lacking Epac1 (Rapgef3). Acta Physiologica 2017 ;Volum 219.(2) s. 441-452 UiB Untitled

33.	Nygaard, Gyrid; Herfindal, Lars; Sivertsen Åsrud, Kathrine; Bjørnstad, Ronja; Kopperud, Reidun Kristin; Oveland, Eystein; Berven, Frode; Myhren, Lene Elisabeth; Høivik, Erling Andre; Lunde, Turid Helen Felli; Bakke, Marit; Doskeland, Stein Ove; Selheim, Frode. Epac1-deficient mice have bleeding phenotype and thrombocytes with decreased GPIbβ expression. Scientific Reports 2017 ;Volum 7:8725. s. 1-15 HAUKELAND UiB SAV Untitled

34.	Wangen, Rebecca. Optimization of Sample Preparation for Mass Spectrometry-Based Quantitative Analysis of All-Trans Retinoic Acid and Valproic Acid Treated Acute Myeloid Leukemia Patients. : Institutt for biomedisin, Universitetet i Bergen 2017 UiB Untitled
2016
35.	Aasebø, Elise; Forthun, Rakel Brendsdal; Berven, Frode; Selheim, Frode; Hernandez-Valladares, Maria. Global cell proteome profiling, phospho-signaling and quantitative proteomics for identification of new biomarkers in acute myeloid leukemia patients. Current Pharmaceutical Biotechnology 2016 ;Volum 17.(1) s. 52-70 UiB Untitled

36.	Aasebø, Elise; Mjaavatten, Olav; Vaudel, Marc; Farag, Yehia Mohamed Mokhtar; Selheim, Frode; Berven, Frode; Bruserud, Øystein; Hernandez-Valladares, Maria. Freezing effects on the acute myeloid leukemia cell proteome and phosphoproteome revealed using optimal quantitative workflows. Journal of Proteomics 2016 ;Volum 145. s. 214-225 UiB Untitled

37.	Hernandez-Valladares, Maria; Aasebø, Elise; Mjaavatten, Olav; Vaudel, Marc; Bruserud, Øystein; Berven, Frode; Selheim, Frode. Reliable FASP-based procedures for optimal quantitative proteomic and phosphoproteomic analysis on samples from acute myeloid leukemia patients. Biological Procedures Online 2016 ;Volum 18:13. s. 1-10 UiB Untitled

38.	Aasebø, Elise; Berven, Frode; Selheim, Frode; Barsnes, Harald; Vaudel, Marc. Interpretation of Quantitative Shotgun Proteomic Data. I: Proteomics in Systems Biology. Springer 2016 ISBN 978-1-4939-3339-6. s. 261-274 HAUKELAND UiB Untitled

39.	Forthun, Rakel Brendsdal; Hinrichs, Carina; Dowling, Tara Helen; Bruserud, Øystein; Selheim, Frode. The past, present and future subclassification of patients with acute Myeloid Leukemia. Current Pharmaceutical Biotechnology 2016 ;Volum 17. s. 6-19 HAUKELAND UiB Untitled

40.	Hernandez Sanchez, Luis Francisco; Aasebø, Elise; Selheim, Frode; Berven, Frode; Ræder, Helge; Barsnes, Harald; Vaudel, Marc. Systemic Analysis of Regulated Functional Networks. Methods in molecular biology 2016 ;Volum 1394. s. 287-310 HAUKELAND UiB Untitled

41.	Hernandez-Valladares, Maria; Aasebø, Elise; Selheim, Frode; Berven, Frode Steingrimsen; Bruserud, Øystein. Selecting Sample Preparation Workflows for Mass Spectrometry-Based Proteomic and Phosphoproteomic Analysis of Patient Samples with Acute Myeloid Leukemia. Proteomes 2016 ;Volum 4.(3) s. - UiB Untitled

42.	Selheim, Frode; Herfindal, Lars. Editorial: Toward Personalized Treatment for Acute Myeloid Leukemia. Current Pharmaceutical Biotechnology 2016 ;Volum 17.(1) s. 4-5 UiB Untitled

43.	Selheim, Frode; Herfindal, Lars. Toward personalized treatment for acute myeloid leukemia. Current Pharmaceutical Biotechnology 2016 ;Volum 17.(1) s. 4-5 UiB Untitled

44.	Vaudel, Marc; Barsnes, Harald; Bjerkvig, Rolf; Bikfalvi, Andreas; Selheim, Frode; Berven, Frode; Daubon, Thomas. Practical considerations for omics experiments in biomedical sciences. Current Pharmaceutical Biotechnology 2016 ;Volum 17.(1) s. 105-114 UiB Untitled
2015
45.	Sleire, Linda; Skeie, Bente Sandvei; Netland, Inger Anne; Førde, Hilde Elise Sundøy; Dodoo, Ernest; Selheim, Frode; Leiss, Lina Wik; Heggdal, Jan Ingemann; Pedersen, Paal-Henning; Wang, Jian; Enger, Per Øyvind. Drug repurposing: Sulfasalazine sensitizes gliomas to gamma knife radiosurgery by blocking cystine uptake through system Xc<sup>-</sup>, leading to glutathione depletion. Oncogene 2015 ;Volum 34.(49) s. 5951-5959 UiB HAUKELAND Untitled
2014
46.	Aasebø, Elise; Vaudel, Marc; Mjaavatten, Olav; Gausdal, Gro; van der Burgh, Arthur Edward Emiel; Gjertsen, Bjørn Tore; Doskeland, Stein Ove; Bruserud, Øystein; Berven, Frode; Selheim, Frode. Performance of super-SILAC based quantitative proteomics for comparison of different acute myeloid leukemia (AML) cell lines. Proteomics 2014 ;Volum 14.(17-18) s. 1971-1976 UiB Untitled

47.	Nygaard, Gyrid; Herfindal, Lars; Kopperud, Reidun Kristin; Aragay, Anna M.; Holmsen, Holm A; Doskeland, Stein Ove; Kleppe, Rune; Selheim, Frode. Time-dependent inhibitory effects of cGMP-analogues on thrombin-induced platelet-derived microparticles formation, platelet aggregation, and P-selectin expression. Biochemical and Biophysical Research Communications - BBRC 2014 ;Volum 449.(3) s. 357-363 UiB Untitled
2013
48.	Herfindal, Lars; Nygaard, Gyrid; Kopperud, Reidun Kristin; Krakstad, Camilla; Doskeland, Stein Ove; Selheim, Frode. Off-target effect of the Epac agonist 8-pCPT-2'-O-Me-cAMP on P2Y12 receptors in blood platelets. Biochemical and Biophysical Research Communications - BBRC 2013 ;Volum 437.(4) s. 603-608 HAUKELAND UiB Untitled

49.	Myhren, Lene Elisabeth; Nygaard, Gyrid; Gausdal, Gro; Sletta, Håvard; Teigen, Knut; Degnes, Kristin Fløgstad; Zahlsen, Kolbjørn; Brunsvik, Anders; Bruserud, Øystein; Doskeland, Stein Ove; Selheim, Frode; Herfindal, Lars. Iodinin (1,6-dihydroxyphenazine 5,10-dioxide) from streptosporangium sp. induces apoptosis selectively in myeloid leukemia cell lines and patient cells. Marine Drugs 2013 ;Volum 11.(2) s. 332-349 HAUKELAND SINTEF UiB Untitled

50.	Nilsson, Carol L.; Berven, Frode; Selheim, Frode; Liu, Huiling; Moskal, Joseph R.; Kroes, Roger A.; Sulman, Erik P.; Conrad, Charles A.; Lang, Frederick F.; Andrén, Per E.; Nilsson, Anna; Carlsohn, Elisabet; Lilja, Hans; Malm, Johan; Fenyö, David; Subramaniyam, Devipriya; Wang, Xiangdong; Gonzales-Gonzales, Maria; Dasilva, Noelia; Diez, Paula; Fuentes, Manuel; Végvári, Ákos; Sjödin, Karin; Welinder, Charlotte; Laurell, Thomas; Fehniger, Thomas E.; Lindberg, Henrik; Rezeli, Melinda; Edula, Goutham; Hober, Sophia; Marko-Varga, Györgi. Chromosome 19 annotations with disease speciation: a first report from the Global Research Consortium. Journal of Proteome Research 2013 ;Volum 12.(1) s. 134-149 UiB Untitled

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