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2019
1 Heggeset, Tonje Marita Bjerkan; Velasco-Rodríguez, Óscar; Degnes, Kristin Fløgstad; Fil, Mariana; Josefsen, Kjell Domaas; Jønsson, Malene; Kraushaar, Konstantin; Haugen, Tone; Barreiro, Carlos; Kroke, Edwin; Sletta, Håvard.
Microbiomes of decaying wood. Functional Metagenomics 2019; 2019-06-16 - 2019-06-19
SINTEF Untitled
 
2 Heggeset, Tonje Marita Bjerkan; Velasco‐Rodriguez, Óscar; Degnes, Kristin Fløgstad; Fil, Mariana; Josefsen, Kjell Domaas; Jønsson, Malene; Kraushaar, Konstantin; Haugen, Tone; Barreiro, Carlos; Kroke, Edwin; Sletta, Håvard.
Microbiomes of decaying wood. Functional Metagenomics 2019; 2019-06-16 - 2019-06-19
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3 Nguyen, Giang-Son; Lewin, Anna; Degnes, Kristin Fløgstad; Klinkenberg, Geir; Sletta, Håvard; Ellingsen, Trond Erling; Liles, Mark R.; Sandoval, Megan; Waits, Damien; Medema, Marnix H.; Navarro Munoz, Jorge; Fernandez‐Guerra, Antonio; Eijsink, Vincent; Wentzel, Alexander.
Exploring the great potential of an Actinobacteria strain collection from Trondheim fjord for the discovery of novel antibiotics and enzyme systems for biomass degradation. BIOPROSP_19; 2019-02-25 - 2019-02-27
SINTEF NMBU NTNU Untitled
 
4 Wentzel, Alexander; Lewin, Anna; Nordborg, Anna; Nguyen, Giang-Son; Degnes, Kristin Fløgstad; Sulheim, Snorre; Borgos, Sven Even F.; Kumelj, Tjasa; Kumar, Kanhaiya; Bruheim, Per; Almaas, Eivind; Liles, Mark R.; Sandoval, Megan; Waits, Damien S.; Mead, David A.; Medema, Marnix H.; Navarro Munoz, Jorge; Fernandez-Guerra, Antonio; van Dissel, Dino; Hulst, Mandy; Chao, Du; Van Wezel, Gilles P.; Wang, Hao; Kerkhoven, Eduard; Salehzadeh-Yazdi, Ali; Wolkenhauer, Olaf; Nieselt, Kay; Iftime, Dumitrita; Bera, Agnieszka; Hinder, Markus; Stegmann, Evi; Wohlleben, Wolfgang; Ellingsen, Trond Erling; Sletta, Håvard.
Expanding the (meta)genomics toolbox for the discovery and production of novel natural products from microbial resources. 2nd Synthetic Biology for Natural Products Conference; 2019-06-02 - 2019-06-05
NTNU SINTEF Untitled
 
5 Wentzel, Alexander; Lewin, Anna; Nordborg, Anna; Nguyen, Giang-Son; Degnes, Kristin Fløgstad; Sulheim, Snorre; Borgos, Sven Even F.; Kumelj, Tjasa; Kumar, Kanhaiya; Bruheim, Per; Almaas, Eivind; Liles, Mark R.; Sandoval, Megan; Waits, Damien S.; Mead, David A.; Medema, Marnix H.; Navarro Munoz, Jorge; Fernandez-Guerra, Antonio; van Dissel, Dino; Hulst, Mandy; Du, Chao; Van Wezel, Gilles P.; Wang, Hao; Kerkhoven, Eduard; Salehzadeh-Yazdi, Ali; Wolkenhauer, Olaf; Nieselt, Kay; Iftime, Dumitrita; Bera, Agnieszka; Hinder, Markus; Stegmann, Evi; Wohlleben, Wolfgang; Ellingsen, Trond Erling; Sletta, Håvard.
Expanding the (meta)genomics toolbox for the discovery and production of novel natural products from microbial resources. Functional Metageomics 2019; 2019-06-16 - 2019-09-19
NTNU SINTEF Untitled
 
2018
6 Degnes, Kristin Fløgstad; Nguyen, Giang-Son; Klinkenberg, Geir; Sletta, Håvard; Lewin, Anna; Nordborg, Anna; Ellingsen, Trond Erling; Sandoval, Megan; Waits, Damien; Mederna, Marnix; Munoz, Jorge Navarro; Fernandez-Guerra, Antonio; Wentzel, Alexander.
Heterologous expression of actinobacterial biosynthetic gene clusters and identification of novel bioactive compounds by multi-omics networking. DLN annual meeting 2018; 2018-03-20 - 2018-03-21
NTNU SINTEF Untitled
 
7 Degnes, Kristin Fløgstad; Nguyen, Giang-Son; Sulheim, Snorre; Klinkenberg, Geir; Sletta, Håvard; Lewin, Anna; Nordborg, Anna; Ellingsen, Trond E; Liles, Mark R.; Sandoval, Megan; Waits, Damien; Medema, Marnix H.; Navarro Munoz, Jorge; Fernandez-Guerra, Antonio; Wentzel, Alexander.
Novel insights into the natural product potential of a marine Actinobacteria strain collection by combining classical and genomics-based bioprospecting. DigitalLife 2018; 2018-03-20 - 2018-03-21
NTNU SINTEF Untitled
 
8 Mead, David A.; Pereira, Alinne; Sandoval, Megan; Zhou, Jinglie; Monsma, Scott; Degnes, Kristin Fløgstad; Nguyen, Giang-Son; Wentzel, Alexander; Liles, Mark R..
Mining and Expressing Biosynthetic Gene Clusters from Soil Metagenomes. SIM Natural Products discovery and development in the genomic era; 2018-04-21 - 2018-04-24
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9 Mead, David A.; Pereira, Alinne; Sandoval-Powers, Megan; Zhou, Jinglie; Scott, Monsma; Degnes, Kristin Fløgstad; Wentzel, Alexander; Liles, Mark R..
Mining and expressing biosynthetic gene clusters from soil metagenomes. SIM2018; 2018-08-12 - 2018-08-16
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10 Nguyen, Giang-Son; Lewin, Anna; Degnes, Kristin Fløgstad; Klinkenberg, Geir; Sletta, Håvard; Ellingsen, Trond E; Liles, Mark R.; Sandoval, Megan; Waits, Damien; Medema, Marnix H.; Navarro Munoz, Jorge; Fernándes-Guerra, Antonio; Eijsink, Vincent.
Actinobacteria from the Trondheim fjord: a promising source of novel bioactive compounds and redox enzyme systems for the biocatalytic conversion of lignocellulose. DigitalLife 2018; 2018-03-20 - 2018-03-21
SINTEF NMBU Untitled
 
11 Sandoval, Megan; Pereira, Alinne; Degnes, Kristin Fløgstad; Wentzel, Alexander; Mead, David A.; Liles, Mark R..
Streptomyces coelicolor Expression of Soil Metagenome-Derived Biosynthetic Gene Clusters. ASM microbe; 2018-06-07 - 2018-06-11
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12 Sulheim, Snorre; Degnes, Kristin Fløgstad; Nguyen, Giang-Son; Wentzel, Alexander; Almaas, Eivind.
A network approach to efficient drug discovery. International School and Conference on Network Science; 2018-06-11 - 2018-06-15
NTNU SINTEF Untitled
 
2017
13 Degnes, Kristin Fløgstad; Kvitvang, Hans Fredrik Nyvold; Haslene-Hox, Hanne; Aasen, Inga Marie.
Changes in the Profiles of Metabolites Originating from Protein Degradation During Ripening of Dry Cured Ham. Food and Bioprocess Technology 2017 ;Volum 10.(6) s. 1122-1130
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14 Nguyen, Giang-Son; Lewin, Anna; Heggeset, Tonje Marita Bjerkan; Degnes, Kristin Fløgstad; Klinkenberg, Geir; Sletta, Håvard; Ellingsen, Trond Erling; Liles, Mark R.; Sandoval, Megan; Waits, Damien; Medema, Marnix H.; Navarro Munoz, Jorge; Fernandez-Guerra, Antonio; Wentzel, Alexander.
Genome sequencing and taxonomic and functional evaluation of 1000 marine Actinobacteria isolates from the Trondheim fjord. Prokagenomics 2017; 2017-09-20 - 2017-09-22
NTNU SINTEF Untitled
 
15 Wentzel, Alexander; Lewin, Anna; Nordborg, Anna; Nguyen, Giang-Son; Degnes, Kristin Fløgstad; Sulheim, Snorre; Kumelj, Tjasa; Bruheim, Per; Almaas, Eivind; Liles, Mark R.; Sandoval, Megan; Waits, Damien; ERASysAPP SYSTERACT cons., The; Ellingsen, Trond Erling; Sletta, Håvard.
New bioactive compounds from environmental microbial resources by an integrated functional (meta)genomics approach. Meeting with the ReDig project; 2017-09-19 - 2017-09-19
NTNU SINTEF UiO Untitled
 
16 Wentzel, Alexander; Lewin, Anna; Nordborg, Anna; Nguyen, Giang-Son; Degnes, Kristin Fløgstad; Sulheim, Snorre; Kumelj, Tjasa; Bruheim, Per; Almaas, Eivind; Liles, Mark R.; Sandoval, Megan; Waits, Damien; ERASysAPP SYSTERACT cons., The; Ellingsen, Trond Erling; Sletta, Håvard.
New bioactive compounds from environmental microbial resources by an integrated functional (meta)genomics approach. Synthetic Biology of Natural Products; 2017-03-05 - 2017-03-08
NTNU SINTEF UiO Untitled
 
17 Wentzel, Alexander; Lewin, Anna; Nordborg, Anna; Nguyen, Giang-Son; Degnes, Kristin Fløgstad; Sulheim, Snorre; Kumelj, Tjasa; Bruheim, Per; Almaas, Eivind; Liles, Mark R.; Sandoval, Megan; Waits, Damien; ERASysAPP SYSTERACT cons., The; Ellingsen, Trond Erling; Sletta, Håvard.
New bioactive compounds from environmental microbial resources by an integrated functional (meta)genomics approach. BioProsp 2017, the 8th International Conference on Marine Biotechnology; 2017-03-08 - 2017-03-10
NTNU SINTEF UiO Untitled
 
18 Wentzel, Alexander; Lewin, Anna; Nordborg, Anna; Nguyen, Giang-Son; Degnes, Kristin Fløgstad; Sulheim, Snorre; Kumelj, Tjasa; Bruheim, Per; Almaas, Eivind; Liles, Mark R.; Sandoval, Megan; Waits, Damien; ERASysAPP SYSTERACT cons., The; Ellingsen, Trond Erling; Sletta, Håvard.
New bioactive compounds from environmental microbial resources by an integrated functional (meta)genomics approach. Centre for Digital Life Norway - Annual conference; 2017-03-20 - 2017-03-21
NTNU SINTEF UiO Untitled
 
2016
19 Heggeset, Tonje Marita Bjerkan; Lewin, Anna; Nguyen, Giang-Son; Nordborg, Anna; Degnes, Kristin Fløgstad; Sletta, Håvard; Zahlsen, Kolbjørn; Ellingsen, Trond Erling; Bruheim, Per; Almaas, Eivind; Wentzel, Alexander.
INBioPharm - Integrated Novel Natural Product Discovery and Production Platform for Accelerated Biopharmaceutical Innovation from Microbial Biodiversity. Functional Metagenomics 2016; 2016-09-25 - 2016-09-28
NTNU SINTEF Untitled
 
20 Sekurova, Olga; Pérez-Victoria, Ignacio; Martin, Jesús; Degnes, Kristin Fløgstad; Sletta, Håvard; Reyes, Fernando; Zotchev, Sergey.
New Deferoxamine Glycoconjugates Produced upon Overexpression of Pathway-Specific Regulatory Gene in the Marine Sponge-Derived Streptomyces albus PVA94-07. Molecules 2016 ;Volum 21.(9:1131)
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2014
21 Aakvik, Trine; Lale, Rahmi; Degnes, Kristin Fløgstad; Lando, Malin; Valla, Svein.
A new and improved host-independent plasmid system for RK2-based conjugal transfer. PLOS ONE 2014 ;Volum 9.(3:e90372) s. -
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22 Aasen, Inga Marie; Degnes, Kristin Fløgstad; Reine, Kristin; Haslene-Hox, Hanne.
Characterization of ripening processes by mass-spectrometric analyses.. 2nd International Symposium on Fermented Meats; 2014-10-19 - 2014-10-23
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23 Gatesoupe, F-J; Huelvan, Christine; Le Bayon, Nicolas; Sever, Armelle; Aasen, Inga Marie; Degnes, Kristin Fløgstad; Mazurais, David; Panserat, Stephane; Zambonino, Jose-Luis; Kaushik, Sadasivam.
The effects of dietary carbohydrate sources and forms on metabolic response and intestinal microbiota in sea bass juveniles, dicentrarchus labrax. Aquaculture 2014 ;Volum 422-423. s. 47-53
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24 Sletta, Håvard; Degnes, Kristin Fløgstad; Herfindal, Lars; Klinkenberg, Geir; Fjærvik, Espen; Zahlsen, Kolbjørn; Brunsvik, Anders; Nygaard, Gyrid; Aachmann, Finn Lillelund; Ellingsen, Trond Erling; Doskeland, Stein Ove; Zotchev, Sergey.
Anti-microbial and cytotoxic 1,6-dihydroxyphenazine-5,10-dioxide (iodinin) produced by Streptosporangium sp. DSM 45942 isolated from the fjord sediment. Applied Microbiology and Biotechnology 2014 ;Volum 98.(2) s. 603-610
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2013
25 Hansen, Bjørn Henrik; Degnes, Kristin Fløgstad; Øverjordet, Ida Beathe; Altin, Dag; Størseth, Trond Røvik.
Metabolic fingerprinting of arctic copepods Calanus finmarchicus, Calanus glacialis and Calanus hyperboreus. Polar Biology 2013 ;Volum 36.(11) s. 1577-1586
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26 Myhren, Lene Elisabeth; Nygaard, Gyrid; Gausdal, Gro; Sletta, Håvard; Teigen, Knut; Degnes, Kristin Fløgstad; Zahlsen, Kolbjørn; Brunsvik, Anders; Bruserud, Øystein; Doskeland, Stein Ove; Selheim, Frode; Herfindal, Lars.
Iodinin (1,6-dihydroxyphenazine 5,10-dioxide) from streptosporangium sp. induces apoptosis selectively in myeloid leukemia cell lines and patient cells. Marine Drugs 2013 ;Volum 11.(2) s. 332-349
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2012
27 Hansen, Bjørn Henrik; Altin, Dag; Olsen, Anders Johny; Degnes, Kristin Fløgstad; Størseth, Trond Røvik; Sletta, Håvard; Tollefsen, Knut-Erik; Nordtug, Trond.
Effects of chemically and mechanically dispersed oil on fitness-related and molecular endpoints in the North Atlantic copepod Calanus finmarchicus. 6th SETAC World Congress; 2012-05-20 - 2012-05-24
OCEAN NTNU SINTEF NMBU Untitled
 
2011
28 Brautaset, Trygve; Sletta, Håvard; Degnes, Kristin Fløgstad; Sekurova, Olga; Bakke, Ingrid; Volokhan, Olga; Andreassen, Trygve; Ellingsen, Trond Erling; Zotchev, Sergey.
New nystatin-related antifungal polyene macrolides with altered polyol region generated via biosynthetic engineering of Streptomyces noursei. Applied and Environmental Microbiology 2011 ;Volum 77.(18) s. 6636-6643
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29 Degnes, Kristin Fløgstad; Størseth, Trond Røvik; Altin, Dag; Sletta, Håvard; Zahlsen, Kolbjørn; Borgos, Sven Even F.; Hansen, Bjørn Henrik.
Metabolic profiling of Calanus finmarchicus to evaluate the impact of waterborne diethanolamine exposure.. SETAC North America 32nd Annual Meeting; 2011-11-14 - 2011-11-17
OCEAN NTNU SINTEF Untitled
 
30 Hansen, Bjørn Henrik; Altin, Dag; Nordtug, Trond; Degnes, Kristin Fløgstad; Sletta, Håvard; Tollefsen, Knut Erik; Olsen, Anders Johny; Breitholtz, M; Størseth, Trond Røvik.
Effects of dispersed oil on the copepod Calanus finmarchicus.. Forskningsseminar Havet og Kysten; 2011-10-25 - 2011-10-25
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31 Hansen, Bjørn Henrik; Altin, Dag; Olsen, Anders Johny; Faksness, Liv Guri; Degnes, Kristin Fløgstad; Størseth, Trond Røvik; Sletta, Håvard; Nordtug, Trond; Tollefsen, Knut Erik.
The copepod Calanus finmarchicus: A promising cold-water model species for ecotoxicity and environmental genomics related to oil exposure.. SETAC North America 32nd Annual Meeting; 2011-11-14 - 2011-11-17
OCEAN NTNU SINTEF NMBU Untitled
 
32 Størseth, Trond Røvik; Hansen, Bjørn Henrik; Degnes, Kristin Fløgstad; Olsen, Anders Johny; Altin, Dag; Nordtug, Trond.
Effects of dispersed oil on key species in the Atlantic Ocean, cod Gadus morhua L., and copepod Calanus finmarchicus, studied by NMR metabolomics.. SETAC North America 32nd Annual Meeting; 2011-11-14 - 2011-11-17
OCEAN NTNU SINTEF Untitled
 
2010
33 Brautaset, Trygve; Jakobsen, Øyvind Mejdell; Degnes, Kristin F.; Netzer, Roman; Nærdal, Ingemar; Krog, Anne; Dillingham, Rick; Flickinger, Michael C.; Ellingsen, Trond Erling.
Bacillus methanolicus pyruvate carboxylase and homoserine dehydrogenase I and II and their roles for L-lysine production from methanol at 50°C. Applied Microbiology and Biotechnology 2010 ;Volum 87.(3) s. 951-964
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34 Engelhardt, Kerstin; Degnes, Kristin F.; Kemmler, M.; Bredholt, Harald; Fjærvik, Espen; Klinkenberg, Geir; Sletta, Håvard; Ellingsen, Trond Erling; Zotchev, Sergey.
Production of a new thiopeptide antibiotic, TP-1161, by a marine Nocardiopsis species. Applied and Environmental Microbiology 2010 ;Volum 76.(15) s. 4969-4976
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35 Engelhardt, Kerstin; Degnes, Kristin F.; Zotchev, Sergey.
Isolation and Characterization of the Biosynthetic Gene Cluster for Thiopeptide Antibiotic TP-1161. Applied and Environmental Microbiology 2010 ;Volum 76.(21) s. 7093-7101
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36 Jørgensen, Hanne; Degnes, Kristin F.; Dikiy, Alexander; Fjærvik, Espen; Klinkenberg, Geir; Zotchev, Sergey.
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449. Applied and Environmental Microbiology 2010 ;Volum 76.(1) s. 283-293
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2009
37 Aakvik, Trine; Degnes, Kristin F.; Dahlsrud, Rannveig; Schmidt, Frank; Dam, Ragnar; Yu, Lihua; Völker, Uwe; Ellingsen, Trond Erling; Valla, Svein.
A plasmid RK2-based broad-host-range cloning vector useful for transfer of metagenomic libraries to a variety of bacterial species. FEMS Microbiology Letters 2009 ;Volum 296.(2) s. 149-158
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38 Engelhardt, Kerstin; Sletta, Håvard; Degnes, Kristin F.; Klinkenberg, Geir; Kemmler, M.; Bredholt, Harald; Ian, Elena; Fjærvik, Espen; Ellingsen, Trond Erling; Zotchev, Sergey.
Isolation of the biosynthetic gene cluster for TP1161, a novel thiazolyl peptide from a marine-derived Nocardiopsis sp. Symposium on the Biology of Streptomyces; 2009-10-07 - 2009-10-11
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39 Jørgensen, Hanne; Degnes, Kristin F.; Sletta, Håvard; Fjærvik, Espen; Dikiy, Alexander; Herfindal, Lars; Bruheim, Per; Klinkenberg, Geir; Bredholt, Harald; Nygård, Gyrid; Døskeland, Stein O.; Ellingsen, Trond Erling; Zotchev, Sergey.
The biosynthesis of macrolactam BE-14106: a new way of generating an aminoacyl starter unit. The Fifteenth International Symposium on the Biology of Actinomycetes 2009 (ISBA15); 2009-08-20 - 2009-08-25
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40 Jørgensen, Hanne; Degnes, Kristin; Sletta, Håvard; Fjærvik, Espen; Dikiy, Alexander; Dikiy, Alexander; Herfindal, Lars; Bruheim, Per; Klinkenberg, Geir; Bredholt, Harald; Nygård, Gyrid; Doskeland, Stein Ove; Ellingsen, Trond E.; Zotchev, Sergey B..
Biosynthesis of Macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit. Chemistry and Biology 2009 ;Volum 16.(10) s. 1109-1121
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41 Jørgensen, Hanne; Engelhardt, Kerstin; Sletta, Håvard; Fjærvik, Espen; Klinkenberg, Geir; Degnes, Kristin F.; Ian, Elena; Bredholt, Harald; Kemmler, M.; Terekhova, Larissa P.; Galatenko, Olga A.; Dikiy, Alexander; Bruheim, Per; Ellingsen, Trond Erling; Zotchev, Sergey.
Streptomycetes and other actinobacteria from the Trondheim fjord (Norway): diversity, secondary metabolites, and genes for their biosynthesis. Symposium on the Biology of Streptomyces; 2009-10-07 - 2009-10-11
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42 Zotchev, Sergey; Jørgensen, Hanne; Degnes, Kristin F.; Sletta, Håvard; Fjærvik, Espen; Dikiy, Alexander; Herfindal, L.; Bruheim, Per; Klinkenberg, Geir; Bredholt, Harald; Nygård, G.; Døskeland, Stein O.; Ellingsen, Trond Erling.
SMALL-RING MACROLACTAMS WITH ACYL SIDE CHAIN: NEW INSIGHTS INTO THE BIOSYNTHESIS AND ITS EVOLUTION. 15th International Symposium on the Biology of Actinomycetes; 2009-08-20 - 2009-08-25
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43 Degnes, Kristin Fløgstad.
A plasmid RK2-based broad-host-range cloning vector useful for transfer of metagenomic libraries to a variety of bacterial species.. FEMS Microbiology Letters 2009 ;Volum 296. s. 149-158
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44 Degnes, Kristin Fløgstad.
THE BIOSYNTHESIS OF MACROLACTAM BE-14106: A NEW WAY OF GENERATING AN AMINOACYL STARTER UNIT. International Symposium on the Biology of Actinomycetes; 2009-08-20 - 2009-08-25
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45 Jakobsen, Øyvind Mejdell; Brautaset, Trygve; Degnes, Kristin F.; Heggeset, Tonje M.B.; Balzer, Simone; Flickinger, Michael C.; Valla, Svein; Ellingsen, Trond Erling.
Overexpression of Wild-Type Aspartokinase Increases L-Lysine Production in the Thermotolerant Methylotrophic Bacterium Bacillus methanolicus. Applied and Environmental Microbiology 2009 ;Volum 75.(3) s. 652-661
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46 Sletta, Håvard; Degnes, Kristin Fløgstad; Klinkenberg, Geir; Ellingsen, Trond Erling.
Isolation of the biosynthetic gene cluster for TP1161, a novel thiazolyl peptide. Biology of Streptomycetes; 2009-10-07 - 2009-10-11
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47 Sletta, Håvard; Klinkenberg, Geir; Degnes, Kristin Fløgstad; Ellingsen, Trond Erling.
Actinobacteria from the Trondheim fjord (Norway): diversity, secondary metabolites, and genes for their biosynthesis. Biology of Streptomycetes; 2009-10-07 - 2009-10-11
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2008
48 Brautaset, Trygve; Sletta, Håvard; Nedal, Aina; Borgos, Sven Even F.; Degnes, Kristin F.; Bakke, Ingrid; Volokhan, Olga; Sekurova, Olga N.; Treshalin, Ivan D.; Mirchink, Elena P.; Dikiy, Alexander; Ellingsen, Trond Erling; Zotchev, Sergey.
Improved Antifungal Polyene Macrolides via Engineering of the Nystatin Biosynthetic Genes in Streptomyces noursei. Chemistry and Biology 2008 ;Volum 15.(11) s. 1198-1206
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