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2021
1 Ræder, Synnøve Brandt; Sandbakken, Erik Thorvaldsen; Nepal, Anala; Løseth, Kirsti; Bergh, Kåre; Witsø, Eivind; Otterlei, Marit.
Novel Peptides Targeting the β-Clamp Rapidly Kill Planktonic and Biofilm Staphylococcus epidermidis Both in vitro and in vivo. Frontiers in Microbiology 2021
STO NTNU Untitled
 
2 Sumabe, Balagra Kasim; Ræder, Synnøve Brandt; Røst, Lisa M.; Sharma, Animesh; Donkor, Eric S.; Mosi, Lydia; Duodu, Samuel; Bruheim, Per; Otterlei, Marit.
Nucleoside Analogues Are Potent Inducers of Pol V-mediated Mutagenesis. Biomolecules 2021 ;Volum 11.(6) s. -
NTNU STO Untitled
 
2020
3 Nedal, Aina; Ræder, Synnøve Brandt; Dalhus, Bjørn; Helgesen, Emily; Forstrøm, Rune Johansen; Lindland, Kim; Sumabe, Balagra Kasim; Martinsen, Jacob H.; Kragelund, Birthe B.; Skarstad, Kirsten Jane; Bjørås, Magnar; Otterlei, Marit.
Peptides containing the PCNA interacting motif APIM bind to the beta-clamp and inhibit bacterial growth and mutagenesis. Nucleic Acids Research (NAR) 2020 ;Volum 48.(10) s. 5540-5554
NTNU OUS UiO Untitled
 
4 Seelinger, Mareike; Søgaard, Caroline Krogh; Otterlei, Marit.
The human RAD5 homologs, HLTF and SHPRH, have separate functions in DNA damage tolerance dependent on the DNA lesion type. Biomolecules 2020 ;Volum 10.(3)
NTNU Untitled
 
5 Røst, Lisa Marie.
Targeted Mass Spectrometric Metabolite Profiling for Studies of Central Carbon Metabolism. Norges teknisk-naturvitenskapelige universitet 2020 (ISBN 978-82-326-4737-8) 180 s.
NTNU Untitled
 
6 Seelinger, Mareike; Otterlei, Marit.
Helicase-Like Transcription Factor HLTF and E3 Ubiquitin Ligase SHPRH Confer DNA Damage Tolerance through Direct Interactions with Proliferating Cell Nuclear Antigen (PCNA). International Journal of Molecular Sciences 2020 ;Volum 21.(693) s. -
NTNU Untitled
 
2019
7 Montaldo, Nicola Pietro; Bordin, Diana Lilian; Brambilla, Alessandro; Rösinger, Marcel; Martin, Sarah Fordyce; Bjørås, Karine Øian; Bradamante, Stefano; Aas, Per Arne; Furrer, Antonia; Olsen, Lene Christin; Kunath, Nicolas; Otterlei, Marit; Sætrom, Pål; Bjørås, Magnar; Samson, Leona D.; van Loon, Barbara.
Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression. Nature Communications 2019 ;Volum 10.(1) s. -
NTNU OUS UiO Untitled
 
8 Prestel, Andreas; Wichmann, Nanna; Martins, Joao M; Marabini, Riccardo; Kassem, Noah; Broendum, Sebastian S; Otterlei, Marit; Nielsen, Olaf; Willemoës, Martin; Ploug, Michael; Boomsma, Wouter; Kragelund, Birthe B.
The PCNA interaction motifs revisited: thinking outside the PIP-box. Cellular and Molecular Life Sciences (CMLS) 2019 ;Volum 76.(24) s. 4923-4943
NTNU Untitled
 
9 Prikrylova, Terezia; Robertson, Julia; Ferrucci, Francesca; Konorska, Dorota Joanna; Aanes, Håvard; Manaf, Adeel; Zhang, Beibei; Vågbø, Cathrine Broberg; Kusnierczyk, Anna; Gilljam, Karin Margaretha; Løvkvam-Køster, Maiken Caroline; Otterlei, Marit; Dahl, John Arne; Enserink, Jorrit; Klungland, Arne; Robertson, Adam Brian.
5-hydroxymethylcytosine marks mammalian origins acting as a barrier to replication. Scientific Reports 2019 ;Volum 9. s. -
NTNU OUS UiO Untitled
 
10 Røst, Lisa Marie; Løkken, Erle Gustavsen; Otterlei, Marit; Bruheim, Per.
Glioblastoma cells respond to hypoxia by increased cell growth and altered TCA-cycle progression. NBS Vintermøte; 2019-01-24 - 2019-01-27
NTNU Untitled
 
11 Søgaard, Caroline Krogh; Nepal, Anala; Petrovic, Voin; Sharma, Animesh; Liabakk, Nina-Beate; Steigedal, Tonje S.; Otterlei, Marit.
Targeting the non-canonical roles of PCNA modifies and increases the response to targeted anti-cancer therapy. OncoTarget 2019 ;Volum 10.(68) s. 7185-7197
NTNU STO Untitled
 
2018
12 Kim, Jana; Søgaard, Caroline Krogh; Kim, Eugene; Bathen, Tone Frost; Otterlei, Marit; Moestue, Siver Andreas; Hill, Deborah Katherine.
Diffusion weighted MRI simplifies therapy monitoring in TRAMP mice. Joint Annual Meeting ISMRM-ESMRMB; 2018-06-16 - 2018-06-21
NTNU Untitled
 
13 Olaisen, Camilla; Kvitvang, Hans Fredrik Nyvold; Lee, Sungmin; Almaas, Eivind; Bruheim, Per; Drabløs, Finn; Otterlei, Marit.
The role of PCNA as a scaffold protein in cellular signaling is functionally conserved between yeast and humans. FEBS Open Bio 2018 ;Volum 8.(7) s. 1135-1145
NTNU Untitled
 
14 Olaisen, Camilla; Røst, Lisa Marie; Nedal, Aina; Petrovic, Voin; Kvitvang, Hans Fredrik Nyvold; Bruheim, Per; Otterlei, Marit.
Proliferating Cell Nuclear Antigen (PCNA) has a Central Role in Regulation of the Glycolysis in Haematological Cancer Cells. Metabolism and Cancer; 2018-09-28 - 2018-10-01
NTNU Untitled
 
15 Petrovic, Voin; Nepal, Anala; Olaisen, Camilla; Bachke, Siri; Hira, Jonathan; Søgaard, Caroline Krogh; Røst, Lisa Marie; Misund, Kristine; Andreassen, Trygve; Melø, Torun Margareta; Bartosova, Zdenka; Bruheim, Per; Otterlei, Marit.
Anti-Cancer Potential of Homemade Fresh Garlic Extract Is Related to Increased Endoplasmic Reticulum Stress. Nutrients 2018 ;Volum 10.(4)
NTNU UiT Untitled
 
16 Ræder, Synnøve Brandt; Nepal, Anala; Bjørås, Karine; Seelinger, Mareike; Kolve, Rønnaug Steen; Nedal, Aina; Müller, Rebekka; Otterlei, Marit.
APIM-mediated REV3L?PCNA interaction important for error free TLS over UV-induced DNA lesions in human cells. International Journal of Molecular Sciences 2018 ;Volum 20.(1) s. -
NTNU STO Untitled
 
17 Søgaard, Caroline Danielsen; Moestue, Siver Andreas; Rye, Morten Beck; Kim, Jana; Nepal, Anala; Liabakk, Nina-Beate; Bachke, Siri; Bathen, Tone Frost; Otterlei, Marit; Hill, Deborah Katherine.
APIM-peptide targeting PCNA improves the efficacy of docetaxel treatment in the TRAMP mouse model of prostate cancer. OncoTarget 2018 ;Volum 9.(14) s. 11752-11766
NORD NTNU STO Untitled
 
18 Søgaard, Caroline Krogh; Blindheim, Augun; Røst, Lisa Marie; Petrovic, Voin; Nepal, Anala; Bachke, Siri; Liabakk, Nina-Beate; Gederaas, Odrun Arna; Viset, Trond; Arum, Carl-Jørgen; Bruheim, Per; Otterlei, Marit.
"Two hits - one stone" increased efficacy of cisplatin-based therapies by targeting PCNA's role in both DNA repair and cellular signaling. OncoTarget 2018 ;Volum 9.(65) s. 32448-32465
NTNU STO Untitled
 
2017
19 Bjørås, Karine; Sousa, Mirta; Sharma, Animesh; Fonseca, Davi de Miranda; Søgaard, Caroline Danielsen; Bjørås, Magnar; Otterlei, Marit.
Monitoring of the spatial and temporal dynamics of BER/SSBR pathway proteins, including MYH, UNG2, MPG, NTH1 and NEIL1-3, during DNA replication. Nucleic Acids Research (NAR) 2017 ;Volum 45.(14) s. 8291-8301
NTNU OUS UiO Untitled
 
20 Petrovic, Voin; Olaisen, Camilla; Sharma, Animesh; Nepal, Anala; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge; Slupphaug, Geir; Otterlei, Marit.
Changes in cellular signaling proteins in extracts from A549, H460, and U2OS cells treated with cisplatin or docetaxel. Data in Brief 2017 ;Volum 12. s. 18-21
NTNU Untitled
 
21 Petrovic, Voin; Olaisen, Camilla; Sharma, Animesh; Nepal, Anala; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge; Slupphaug, Geir; Otterlei, Marit.
On-column trypsinization allows for re-use of matrix in modified multiplexed inhibitor beads assay. Analytical Biochemistry 2017 ;Volum 523. s. 10-16
NTNU Untitled
 
22 Sousa, Mirta; Bjørås, Karine; Hanssen-Bauer, Audun; Solvang-Garten, Karin; Otterlei, Marit.
P38 MAPK signaling and phosphorylations in the BRCT1 domain regulate XRCC1 recruitment to sites of DNA damage. Scientific Reports 2017 ;Volum 7.(1)
NTNU Untitled
 
2016
23 Marstad, Anne; Landsverk, Ole J. B.; Strømme, Olaf; Otterlei, Marit; Collas, Philippe; Sundan, Anders; Brede, Gaute.
A-kinase anchoring protein AKAP95 is a novel regulator of ribosomal RNA synthesis. The FEBS Journal 2016 ;Volum 283.(4) s. 757-770
NTNU OUS UiO Untitled
 
24 Røst, Lisa Marie; Olaisen, Camilla; Petrovic, Voin; Otterlei, Marit; Bruheim, Per.
Blocking the Stress-specific APIM-PCNA Interaction in Multiple Myeloma Cells Cause Significant Changes in Central Carbon Metabolism. ISCaM 2016: Metabolic Networks in Cancer; 2016-10-26 - 2016-10-29
NTNU Untitled
 
25 Søgaard, Caroline Danielsen; Petrovic, Voin; Blindheim, Augun; Gederaas, Odrun Arna; Arum, Carl-Jørgen; Otterlei, Marit.
PCNA-targeting APIM-peptide alters response to DNA damage in human bladder cancer cells on a signaling level. 2nd EMBO Cellular Signalling & Cancer Therapy Conference; 2016-05-27 - 2016-05-31
NTNU Untitled
 
2015
26 Olaisen, Camilla; Müller, Rebekka; Nedal, Aina; Otterlei, Marit.
PCNA-interacting peptides reduce Akt phophorylation and TLR-mediated cytokine secretion suggesting a role of PCNA in cellular signaling. Cellular Signalling 2015 ;Volum 27.(7) s. 1478-1487
NTNU Untitled
 
2014
27 Baglo, Yan; Hagen, Lars; Høgset, Anders; Drabløs, Finn; Otterlei, Marit; Gederaas, Odrun Arna.
Enhanced efficacy of bleomycin in bladder cancer cells by photochemical internalization. BioMed Research International 2014 ;Volum 14.(74) s. -
NTNU Untitled
 
28 Gederaas, Odrun Arna; Søgaard, Caroline Danielsen; Viset, Trond; Bachke, Siri; Bruheim, Per; Arum, Carl-Jørgen; Otterlei, Marit.
Increased anticancer efficacy of intravesical mitomycin C therapy when combined with a PCNA targeting peptide. Translational Oncology 2014 ;Volum 7.(6) s. 812-823
NTNU STO Untitled
 
2013
29 Hegre, Siv Anita; Sætrom, Pål; Aas, Per Arne; Pettersen, Henrik P Sahlin; Otterlei, Marit; Krokan, Hans Einar.
Multiple microRNAs may regulate DNA repair enzyme uracil‐DNA glycosylase. DNA Repair 2013 ;Volum 12.(1) s. 80-86
NTNU Untitled
 
30 Müller, Rebekka; Misund, Kristine; Holien, Toril; Bachke, Siri; Gilljam, Karin Margaretha; Våtsveen, Thea Kristin; Rø, Torstein Baade; Bellacchio, E.; Sundan, Anders; Otterlei, Marit.
Targeting Proliferating Cell Nuclear Antigen and Its Protein Interactions Induces Apoptosis in Multiple Myeloma Cells. PLOS ONE 2013 ;Volum 8.(7) s. -
NTNU Untitled
 
2012
31 Arum, Carl-Jørgen; Gederaas, Odrun; Bachke, Siri; Viset, Trond; Otterlei, Marit.
Targeting DNA repair mechanisms increases efficiency of intravesical chemotherapy in an orthotopic rat bladder model. info kommer; 2012-11-30 - 2012-11-30
NTNU STO Untitled
 
32 Baglo, Yan; Müller, Rebekka; Otterlei, Marit; Gederaas, Odrun Arna.
Analysis of stress responses induced by hexylaminolevulinate-mediated photodynamic treatment. NBS winter meeting 2012; 2012-01-19 - 2012-01-22
NTNU Untitled
 
33 Bjørnstad, Linn; Meza, Trine Johansen; Otterlei, Marit; Olafsrud, Solveig Mjelstad; Meza-Zepeda, Leonardo Andrés; Falnes, Pål.
Human ALKBH4 Interacts with Proteins Associated with Transcription. PLOS ONE 2012 ;Volum 7.(11) s. -
NTNU OUS UiO Untitled
 
34 Gederaas, Odrun; Bachke, Siri; Sørgaard, Caroline Danielsen; Viset, Trond; Arum, Carl-Jørgen; Otterlei, Marit.
Increased efficacy of intravesical chemotherapy in an orthotopic rat bladder cancer model by targeting PCNA with the novel synthetic peptide drug ATX-101. Congress, USA. Urology (korrekt navn blir supplert); 2012-11-30 - 2012-11-30
NTNU STO UiT Untitled
 
35 Gilljam, Karin Margaretha; Müller, Rebekka; Liabakk, Nina-Beate; Otterlei, Marit.
Nucleotide excision repair is associated with the replisome and its efficiency depends on a direct interaction between XPA and PCNA. PLOS ONE 2012 ;Volum 7.(11) s. -
NTNU Untitled
 
36 Hanssen-Bauer, Audun; Solvang-Garten, Karin; Akbari, Mansour; Otterlei, Marit.
X-ray repair cross complementing protein 1 in base excision repair. International Journal of Molecular Sciences 2012 ;Volum 13.(12) s. 17210-17229
NTNU Untitled
 
37 Hanssen-Bauer, Audun; Solvang-Garten, Karin; Gilljam, Karin Margaretha; Torseth, Kathrin; Wilson, David M.; Akbari, Mansour; Otterlei, Marit.
The region of XRCC1 which harbours the three most common nonsynonymous polymorphic variants, is essential for the scaffolding function of XRCC1. DNA Repair 2012 ;Volum 11.(4) s. 357-366
NTNU Untitled
 
38 Otterlei, Marit.
APIM-peptides targeting PCNA induce apoptosis in cancer cells. The 3rd Erling Seeberg Symposium on DNA Repair; 2012-07-19 - 2012-07-23
NTNU Untitled
 
39 Otterlei, Marit; Müller, R.; Gilljam, Karin Margaretha; Holien, Toril; Midsund, K.; Vatsveen, TK; Ro, T.B.; Bellacchio, E.; Sundan, Anders.
PEPTIDES COMPRISING THE NOVEL PCNA INTERACTING SEQUENCE APIM, INCREASES THE CYTOTOXICITY OF CHEMOTHERAPEUTIC DRUGS BY IMPAIRING THE CELLS DEFENSE MECHANISMS. Annals of Oncology 2012 ;Volum 23. s. 37-37
NTNU Untitled
 
40 Torseth, Kathrin; Doseth, Berit; Hagen, Lars; Olaisen, Camilla; Liabakk, Nina-Beate; Græsmann, Heidi; Durandy, Anne; Otterlei, Marit; Krokan, Hans Einar; Kavli, Bodil Merete; Slupphaug, Geir.
The UNG2 Arg88Cys variant abrogates RPA-mediated recruitment of UNG2 to single-stranded DNA. DNA Repair 2012 ;Volum 11.(6) s. 559-569
NTNU Untitled
 
2011
41 Alevizopoulos, K; Otterlei, Marit.
ATX-101, a novel APIM-motif comprising peptide drug potentiates the action of several chemotherapeutic drugs by blocking the interaction between PCNA and key proteins involved in DNA repair and cell cycle control. Annals of Oncology 2011 ;Volum 22. s. 43-43
NTNU Untitled
 
42 Baglo, Yan; Müller, Rebekka; Otterlei, Marit; Gederaas, Odrun Arna.
Analysis of stress responses induced by hexylaminolevulinate-mediated photodynamic treatment. 14th Congress of the European Society for Photobiology; 2011-09-01 - 2011-09-06
NTNU Untitled
 
43 Hanssen-Bauer, Audun; Solvang-Garten, Karin; Sundheim, Ottar; Diaz, Javier Pena; Andersen, Sonja Benedikte; Slupphaug, Geir; Krokan, Hans Einar; Wilson, David M.; Akbari, Mansour; Otterlei, Marit.
XRCC1 Coordinates Disparate Responses and Multiprotein Repair Complexes Depending on the Nature and Context of the DNA Damage. Environmental and Molecular Mutagenesis 2011 ;Volum 52.(8) s. 623-635
NTNU Untitled
 
44 Müller, Rebekka; Giljam, Karin Margaretha; Liabakk, Nina-Beate; Otterlei, Marit.
Efficient repair of UV-induced DNA damage during replication depends on direct XPA-PCNA interaction. Eukaryotic DNA Replication & Genome Maintenance; 2011-09-06 - 2011-09-10
NTNU Untitled
 
45 Müller, Rebekka; Jacob, Havjin; Bachke, Siri; Giljam, Karin Margaretha; Otterlei, Marit.
Inhibition of the NF-kappaB pathway by the APIM-peptide. Responses to DNA damage: from molecular mechanism to human disease; 2011-04-03 - 2011-04-08
NTNU Untitled
 
46 Sletta, Håvard; Klinkenberg, Geir; Winnberg, Asgeir; Kvitvang, Hans Fredrik Nyvold; Nilsen, Marianne Bakke; Krokan, Hans Einar; Otterlei, Marit; Bruheim, Per.
A new high resolution screening method for study of phenotype stress responses of Saccharomyces cerevisae mutants. Journal of Microbiological Methods 2011 ;Volum 87.(3) s. 363-367
NTNU SINTEF Untitled
 
2010
47 Akbari, Mansour; Solvang-Garten, Karin; Hanssen-Bauer, Audun; Lieske, Nora V.; Pettersen, Henrik P Sahlin; Pettersen, Grete Klippenvåg; Wilson, DM; Krokan, Hans Einar; Otterlei, Marit.
Direct interaction between XRCC1 and UNG2 facilitates rapid repair of uracil in DNA by XRCC1 complexes. DNA Repair 2010 ;Volum 9.(7) s. 785-795
NTNU Untitled
 
48 Arum, Carl-Jørgen; Kodama, Yosuke; Rolim, Natale Pinheiro Lage; Widerøe, Marius; Anderssen, Endre; Viset, Trond; Otterlei, Marit; Lundgren, Steinar; Chen, Duan; Zhao, Chun-Mei.
A rat model of intravesical delivery of small interfering RNA for studying urinary carcinoma. World Journal of Urology 2010 ;Volum 28.(4) s. 479-485
NTNU STO Untitled
 
49 Gilljam, Karin Margaretha; Feyzi, Emadoldin; Aas, Per Arne; Vågbø, Cathrine Broberg; Müller, rebecca; Catterall, Tara C; Liabakk, Nina-Beate; Slupphaug, Geir; Drabløs, Finn; Krokan, Hans Einar; Otterlei, Marit.
Identification of a new and widespread and functionally important PCNA-binding motif. 6th Norwegian National Proteomics Meeting; 2010-12-09 - 2010-12-10
NTNU Untitled
 
50 Krokan, Hans Einar; Kavli, Bodil Merete; Otterlei, Marit; Akbari, M.; Slupphaug, Geir; Aas, Per Arne.
DNA repair and cancer. European Journal of Cancer 2010 ;Volum 8.(5) s. 7-7
NTNU Untitled
 
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