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2017
1 Haghdani, Shokouh; Hoff, Bård Helge; Koch, Henrik; Åstrand, Per-Olof.
Solvent Effects on Optical Rotation: On the Balance between Hydrogen Bonding and Shifts in Dihedral Angles. Journal of Physical Chemistry A 2017 ;Volum 121.(5) s. 4765-4777
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2 Hoff, Bård Helge; Sundby, Eirik.
Is literature data useful for identifying enzyme catalysts for new substrates? A case study on reduction of 1-aryl-2-alkanoates. Bioorganic chemistry (Print) 2017 ;Volum 74. Suppl. 38 pages s. 260-271
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3 Mihiretu, Gezahegn T.; Brodin, Malin; Chimphango, Annie F.; Øyaas, Karin; Hoff, Bård Helge; Görgens, Johann F..
Single-step microwave-assisted hot water extraction of hemicelluloses from selected lignocellulosic materials – A biorefinery approach. Bioresource Technology 2017 ;Volum 242. s. 669-680
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4 Petrovic, Voin; Olaisen, Camilla; Sharma, Animesh; Nepal, Anala; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge; Slupphaug, Geir; Otterlei, Marit.
Changes in cellular signaling proteins in extracts from A549, H460, and U2OS cells treated with cisplatin or docetaxel. Data in Brief 2017 ;Volum 12. s. 18-21
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5 Petrovic, Voin; Olaisen, Camilla; Sharma, Animesh; Nepal, Anala; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge; Slupphaug, Geir; Otterlei, Marit.
On-column trypsinization allows for re-use of matrix in modified multiplexed inhibitor beads assay. Analytical Biochemistry 2017 ;Volum 523. s. 10-16
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6 Willumsen, Fredrik Bysting; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge.
Investigation of Heck coupling on 6-bromo[2,3-d]thienopyrimidines for construction of new EGFR inhibitor lead structures. RSC Advances 2017 ;Volum 7.(30) s. 18569-18577
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2016
7 Birkeland, Benedicte; Kringhaug, Henrik Holthe; Aae, Bjørn Erik Sylthe; Buene, Audun Formo; Hoff, Bård Helge; Gautun, Odd Reidar.
Synthesis of phenothiazine dyes for dye-sensitized solar cells (DSSC). 31st Organic Chemistry Winter Meeting OKV2016; 2016-01-07 - 2016-01-10
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8 Buene, Audun Formo; Hoff, Bård Helge; Gautun, Odd Reidar.
Synthesis of Phenothiazine-based Dyes for Dye-Sensitized Solar Cells. COREM Workshop; 2016-12-07 - 2016-12-08
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9 Bugge, Steffen; Buene, Audun Formo; Jurisch-Yaksi, Nathalie; Moen, Ingri Ullestad; Skjønsfjell, Ellen Martine; Sundby, Eirik; Hoff, Bård Helge.
Extended structure-activity study of thienopyrimidine-based EGFR inhibitors with evaluation of drug-like properties. European Journal of Medicinal Chemistry 2016 ;Volum 107. s. 255-274
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10 Haghdani, Shokouh; Hoff, Bård Helge; Koch, Henrik; Åstrand, Per-Olof.
Implicit and Explicit Solvent Effects on Optical Rotation for Molecules with Internal Hydrogen Bonds. 6th EuCheMs Chemistry Congress; 2016-09-11 - 2016-09-15
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11 Haghdani, Shokouh; Hoff, Bård Helge; Koch, Henrik; Åstrand, Per-Olof.
Optical Rotation Calculations for a Group of Fluorinated Alcohols and Amines. 17th Tetrahedron Symposium; 2016-06-28 - 2017-07-01
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12 Haghdani, Shokouh; Hoff, Bård Helge; Koch, Henrik; Åstrand, Per-Olof.
Optical Rotation Calculations for Fluorinated Alcohols, Amines, Amides, and Esters. Journal of Physical Chemistry A 2016 ;Volum 120.(40) s. 7973-7986
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13 Han, Jin; Henriksen, Silje; Nørsett, Kristin Gabestad; Sundby, Eirik; Hoff, Bård Helge.
Balancing potency, metabolic stability and permeability in pyrrolopyrimidine-based EGFR inhibitors. European Journal of Medicinal Chemistry 2016 ;Volum 124. s. 583-607
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14 Han, Jin; Kaspersen, Svein Jacob; Nervik, Sondre; Nørsett, Kristin; Sundby, Eirik; Hoff, Bård Helge.
Chiral 6-aryl-furo[2,3-d]pyrimidin-4-amines as EGFR inhibitors. European Journal of Medicinal Chemistry 2016 ;Volum 119. s. 278-299
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15 Han, Jin; Sundby, Eirik; Hoff, Bård Helge.
Balancing potency, metabolic stability and permeability in pyrrolopyrimidine based EGFR-TK inhibitors. Organisk kjemisk vintermøte OKV31; 2016-01-07 - 2016-01-10
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16 Larsen, Kristin Uhlving; Han, Jin; Aarhus, Thomas Ihle; Sundby, Eirik; Hoff, Bård Helge.
Synthesis of pyrrolopyrimidines for use in SAR study of CSF-1R kinase. Organisk Kjemisk vintermøte OKV31; 2016-01-07 - 2016-01-10
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17 Larsen, Kristin Uhlving.
Synthesis of Pyrrolopyrimidines as CSF-1R Kinase Inhibitors. : NTNU-IKJ 2016 304 s.
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18 Reiersølmoen, Ann Christin; Han, Jin; Sundby, Eirik; Hoff, Bård Helge.
Synthesis of pyrrolopyrimidines with acrylate warehead for irreversible inhibition. Organisk Kjemisk vintermøte OKV31; 2016-01-07 - 2016-01-10
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19 Reiersølmoen, Ann Christin.
Synthesis of 5-Aryl-Pyrrolo[2,3-d]pyrimidines and Their Bioactivity. : NTNU-IKJ 2016 394 s.
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20 Uggerud, Nora; Buene, Audun Formo; Gautun, Odd Reidar; Hoff, Bård Helge.
Route selection in preaparation of phenothiazine dye. Organisk Kjemisk vintermøte OKV31; 2016-01-07 - 2016-01-10
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21 Uggerud, Nora.
Synthesis of 10H-Phenothiazines for Investigation of Π-linker Effect in Dye-Sensitized Solar Cells. : NTNU-IKJ 2016 264 s.
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2015
22 Bekkevard, Pål Unnerud; Han, Jin; Sundby, Eirik; Hoff, Bård Helge.
Instability of 7N-protected pyrrolo[2,3-d]pyrimidines. Organisk kjemisk vintermøte; 2015-01-08 - 2015-01-11
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23 Bekkevard, Pål Unnerud.
Synthesis of Pyrrolopyrimidines for Investigation of JAK2 Inhibition. : NTNU, IKJ 2015 177 s.
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24 Berg, Håvard.
Syntese av nitrogenholdige heterosykler med kirale substituenter - Utforsking av JAK2 hemming. : NTNU, IKJ 2015 152 s.
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25 Buene, Audun Formo; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge.
Synthesis of amide containing thienopyrimidines. Organisk kjemisk vintermøte OKV 30; 2015-01-08 - 2015-01-11
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26 Buene, Audun Formo.
Synthesis of Thieno[2,3-d]pyrimidine-Based EGFR-TK Inhibitors with Improved Solubility and Metabolic Stability. : NTNU, IKJ 2015 300 s.
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27 Bugge, Steffen.
Development of Thienopyrimidines as Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors. Trondheim: NTNU 2015 (ISBN 978-82-326-1046-4) ;Volum 2015.296 s. Doktoravhandlinger ved NTNU(195)
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28 Bugge, Steffen; Moen, Ingri Ullestad; Sylte, Kent-Ove Kragseth; Sundby, Eirik; Hoff, Bård Helge.
Truncated structures used in search for new lead compounds and in a retrospective analysis of thienopyrimidine-based EGFR inhibitors. European Journal of Medicinal Chemistry 2015 ;Volum 94. s. 175-194
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29 Gulbrandsen, Tore Aarhus; Johnsen, Ingvild Andersen; Opedal, Mihaela Tanase; Toven, Kai; Øyaas, Karin; Pranovich, Andrey; Mikkola, Jyri-Pekka; Hoff, Bård Helge.
Extracting hemicelluloses from softwood and bagasse as oligosaccharides using pure water and microwave heating. Cellulose Chemistry and Technology 2015 ;Volum 49.(2) s. 117-126
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30 Haghdani, Shokouh; Hoff, Bård Helge; Koch, Henrik; Åstrand, Per-Olof.
Optical Rotation Calculations of Fluorinated Alcohols and Amines. Annual Meeting in Quantum and Computational Chemistry; 2015-06-29 - 2015-06-30
NTNU Untitled
 
31 Haghdani, Shokouh; Hoff, Bård Helge; Koch, Henrik; Åstrand, Per-Olof.
Optical Rotation Calculations of Fluorinated Alcohols and Amines: The Role of Basis Set Convergence. 10th European Conference on Computational Chemistry (EuCO-CC 2015); 2015-08-31 - 2015-09-03
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32 Han, Jin; Kaspersen, Svein Jacob; Sundby, Eirik; Hoff, Bård Helge.
Highly potent pyrrolo[2,3-d]pyrimidines as EGFR-TK inhibitors with interesting Src-familiy and CSF1R activity. Organisk kjemisk Vintermøte OKV 30; 2015-01-08 - 2015-01-11
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33 Henriksen, Silje; Han, Jin; Sundby, Eirik; Hoff, Bård Helge.
Chiral pyrrolopyrimidine based EGFR inhibitors. Organisk kjemisk vintermøte OKV 30; 2015-01-08 - 2015-01-11
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34 Henriksen, Silje.
Synthesis of 6-Aryl-pyrrolopyrimidines - Effect of ortho Substituents on EGFR Inhibitory Activity. : NTNU, IKJ 2015 194 s.
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35 Hoff, Bård Helge; Sundby, Eirik.
Thieno- and pyrrolopyrimidine based epidermal growth factor inhibitors: synthesis, SAR study, cellular profiling and ADME challenges. Lecture at Bar Ilan University; 2015-11-19 - 2015-11-19
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36 Hoff, Bård Helge; Sundby, Eirik; Han, Jin; Bugge, Steffen.
Thieno- and Pyrrolo[2,3-d]pyrimidine base EGFR inhibitors and their ADME profile. , International Symposium in Synthetic and Medicinal Chemistry; 2015-11-15 - 2015-11-18
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37 Karlsen, Morten; Liu, Huiling; Johansen, Jon Eigill; Hoff, Bård Helge.
Economical Synthesis of 13C-Labeled Opiates, Cocaine Derivatives and Selected Urinary Metabolites by Derivatization of the Natural Products. Molecules 2015 ;Volum 20.(4) s. 5329-5345
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38 Nervik, Sondre; Han, Jin; Sundby, Eirik; Hoff, Bård Helge.
Furopyrimidines as EGFR tyrosine kinase inhibitors. Organisk kjemisk vintermøte OKV 30; 2015-01-08 - 2015-01-11
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39 Nervik, Sondre.
Synthesis and Biological Evaluation of Furo[2,3-d]pyrimidines as EGFR Tyrosine Kinase Inhibitors. : NTNU, IKJ 2015 191 s.
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40 Sundby, Eirik; Han, Jin; Kaspersen, Svein Jacob; Hoff, Bård Helge.
In vitro baselining of new pyrrolopyrimidine EGFR-TK inhibitors with Erlotinib. European Journal of Pharmaceutical Sciences 2015 ;Volum 80. s. 56-65
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41 Sundby, Eirik; Hoff, Bård Helge; Han, Jin; Bugge, Steffen; Kaspersen, Jacob.
Preparation of aminoarylpyrimidine derivatives for use as EGFR tyrosine kinase inhibitors. [Patent] Patentnr./Lisensnr.: WO 2015000959 Registrert 2015-01-08
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42 Willumsen, Fredrik Bysting; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge.
Optimization of Heck reaction on the thienopyrimidine scaffold. Organisk kjemisk vintermøte OKV 30; 2015-01-08 - 2015-01-11
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43 Willumsen, Fredrik Bysting.
The Heck reaction for synthesis of novel kinase inhibitors.. : NTNU, IKJ 2015 195 s.
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2014
44 Bugge, Steffen; Kaspersen, Svein Jacob; Larsen, Synne; Nonstad, Unni; Bjørkøy, Geir; Sundby, Eirik; Hoff, Bård Helge.
Structure-activity study leading to identification of a highly active thienopyrimidine based EGFR inhibitor. European Journal of Medicinal Chemistry 2014 ;Volum 75. Suppl. ja s. 354-374
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45 Bugge, Steffen; Kaspersen, Svein Jacob; Sundby, Eirik; Hoff, Bård Helge.
Structure-activity study leading to the identification of a highly active thienopyrimidine based EGFR inhibitor. Organisk kjemisk vintermøte 2014; 2014-01-09 - 2014-01-12
NTNU Untitled
 
46 Bugge, Steffen; Kaspersen, Svein Jacob; Sundby, Eirik; Hoff, Bård Helge.
Use of the thienopyrimidine scaffold for development of new EGFR-TK inhibitors. Kinase 2014: Past, Present and Beyond. 19-20 May 2014; 2014-05-19 - 2014-05-20
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47 Bugge, Steffen; Skjønsfjell, Ellen Martine; Willumsen, Fredrik Bysting; Sundby, Eirik; Hoff, Bård Helge.
Improved and Scalable Preparation of 6-Bromo-4-Chlorothieno[2,3-d]Pyrimidine. Chemistry of Heterocyclic Compounds 2014 ;Volum 50.(8) s. 1177-1187
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48 Han, Jin; Bartling, Christian; Sundby, Eirik; Hoff, Bård Helge.
Challanges in synthesis of electron rich furopyrimidines. Organisk kjemisk vintermøte 2014; 2014-01-09 - 2014-01-12
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49 Han, Jin; Kaspersen, Svein Jacob; Sundby, Eirik; Hoff, Bård Helge.
Highly potent pyrrolo[2,3-d]pyrimidines as EGFR-TK inhibitors with interesting Src-family and CSF1R activity. Kinase 2014: Past, Present and Beyond. 19-20 May 2014; 2014-05-19 - 2014-05-20
NTNU Untitled
 
50 Karlsen, Morten.
Synthesis of 13C-labeled drugs of abuse as internal standards for reducing differences in ion suppressing/alteration effects in LC/MS-MS quantification. Trondheim: NTNU 2014 (ISBN 978-82-326-0614-6) ;Volum 2014.180 s. Doktoravhandlinger ved NTNU(351)
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