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2019
1 Sofias, Alexandros Marios; Pérez-Medina, Carlos; Mulder, Willem J.M.; Hak, Sjoerd.
Unraveling the intricate in vivo fate of active-targeting nanomedicines. NanoSymposium 2019; 2019-10-16 - 2019-10-17
NTNU Untitled
 
2018
2 Hak, Sjoerd; Hagen, Nils; Sofias, Alexandros Marios; Åslund, Andreas; Davies, Catharina de Lange.
Simple and robust intravital microscopy procedures in TIE2GFP mice. ESCDD 2018; 2018-04-11 - 2018-04-13
NTNU Untitled
 
3 Sofias, Alexandros Marios; Andreassen, Trygve; Hak, Sjoerd.
Nanoparticle Ligand-Decoration Procedures Affect in Vivo Interactions with Immune Cells. Molecular Pharmaceutics 2018 ;Volum 15.(12) s. 5754-5761
NTNU Untitled
 
4 Sofias, Alexandros Marios; Hak, Sjoerd.
Embracing the Stealth Mode: Composing cRGD-modified lipid based nanoparticles able to escape extensive phagocytosis. CRS 2018; 2018-07-22 - 2018-07-24
NTNU Untitled
 
5 Sofias, Alexandros Marios; Ochando, Jordi; Flobak, Åsmund; Mulder, Willem J. M.; Hak, Sjoerd.
Tumor targeting by cRGD-modified nanoparticles is dominated by immune cell hitchhiking. WMIC 2018; 2018-09-12 - 2018-09-15
NTNU Untitled
 
6 Sofias, Alexandros Marios; Ochando, Jordi; Grendstad, Kristin; Flobak, Åsmund; Mulder, Willem J. M.; Hak, Sjoerd.
Tumor angiogenesis targeting by cRGD-modified nanoparticles is dominated by neutrophil hitchhiking. ESCDD 2018; 2018-04-11 - 2018-04-13
NTNU Untitled
 
7 Sofias, Alexandros Marios; Ochando, Jordi; Mulder, Willem J. M.; Hak, Sjoerd.
Circulating phagocytes contribute to angiogenesis targeting by cRGD-conjugated nanoparticles. NanoDDS 2018; 2018-09-21 - 2018-09-23
NTNU Untitled
 
8 Sofias, Alexandros Marios; Ochando, Jordi; Mulder, Willem J. M.; Hak, Sjoerd.
Hitchhiking with immune cells: Dominant tumor targeting mechanism for cRGD-modified nanoparticles. TMII 2018; 2018-04-26
NTNU Untitled
 
9 Witzigmann, Dominik; Hak, Sjoerd; van der Meel, Roy.
Translating nanomedicines: Thinking beyond materials? A young investigator's reply to `The Novelty Bubble’. Journal of Controlled Release 2018 ;Volum 290. s. 138-140
NTNU Untitled
 
2017
10 Molska, Alicja; Sofias, Alexandros Marios; Nyman, Axel Karl Gottfrid; Hak, Sjoerd; Widerøe, Marius.
Melatonin treatment for hypoxic-ischemic brain injury. Lipid-based nanoparticles as a platform for drug delivery.. The 5th National PhD Conference in Neuroscience; 2017-09-20 - 2017-09-22
NTNU Untitled
 
11 Perez-Medina, Carlos; Hak, Sjoerd; Reiner, Thomas; Fayad, Zahi A; Nahrendorf, Matthias; Mulder, Willem J. M..
Integrating nanomedicine and imaging. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 2017 ;Volum 375.(2107)
NTNU Untitled
 
12 Sanchez-Gaytan, Brenda L; Fay, Francois; Hak, Sjoerd; Alaarg, Amr; Fayad, Zahi A; Perez-Medina, Carlos; Mulder, Willem J M; Zhao, Yiming.
Real-Time Monitoring of Nanoparticle Formation by FRET Imaging. Angewandte Chemie International Edition 2017 ;Volum 56.(11) s. 2923-2926
NTNU Untitled
 
13 Singh, Gurvinder; McDonagh, Birgitte Hjelmeland; Hak, Sjoerd; Peddis, Davide; Bandyopadhyay, Sulalit; Sandvig, Ioanna; Sandvig, Axel; Glomm, Wilhelm.
Synthesis of gadolinium oxide nanodisks and gadolinium doped iron oxide nanoparticles for MR contrast agents. Journal of materials chemistry. B 2017 ;Volum 5.(3) s. 418-422
NTNU SINTEF Untitled
 
2016
14 Hak, Sjoerd; Zhao, Yiming; Mulder, Willem J.M.; de Lange Davies, Catharina; Haraldseth, Olav.
A fluorescence Resonance energy transfer method to study payload release kinetics from lipid-based nanoparticles. European Symposium on Controlled Drug Delivery; 2016-04-13 - 2016-04-15
NTNU Untitled
 
15 McDonagh, Birgitte Hjelmeland; Singh, Gurvinder; Hak, Sjoerd; Bandyopadhyay, Sulalit; Augestad, Ingrid Lovise; Peddis, Davide; Sandvig, Ioanna; Sandvig, Axel; Glomm, Wilhelm.
L-DOPA-Coated Manganese Oxide Nanoparticles as Dual MRI Contrast Agents and Drug-Delivery Vehicles. Small 2016 ;Volum 12.(3) s. 301-306
NTNU SINTEF Untitled
 
16 Molska, Alicja; Hak, Sjoerd; Widerøe, Marius.
Lipid-based nanoparticles as a platform for drug delivery - melatonin treatment of hypoxic-ischemic brain injury.. The 8th National PhD Conference in Medical Imaging; 2016-11-21 - 2016-11-22
NTNU Untitled
 
17 Snipstad, Sofie; Hak, Sjoerd; Baghirov, Habib; Sulheim, Einar; Mørch, Ýrr Asbjørg; Lelu, Sylvie; von Haartman, Eva; Bäck, Marcus; Nilsson, Peter R; Klymchenko, Andrey S; Davies, Ruth Catharina de Lange; Åslund, Andreas.
Labeling nanoparticles: Dye leakage and altered cellular uptake. Cytometry Part A 2016 ;Volum 91.(8) s. 760-766
NTNU SINTEF Untitled
 
18 Sofias, Alexandros Marios; Widerøe, Marius; Davies, Catharina De Lange; Haraldseth, Olav; Hak, Sjoerd.
Elucidating targeting kinetics towards integrins: A quantitative study. The 8th National PhD Conference in Medical Imaging - MedIm 2016; 2016-11-21 - 2016-11-22
NTNU Untitled
 
19 Zhao, Yiming; Fay, Francois; Hak, Sjoerd; Manuel Perez-Aguilar, Jose; Sanchez-Gaytan, Brenda L; Goode, Brandon; Duivenvoorden, Raphael; Davies, Ruth Catharina de Lange; Bjørkøy, Astrid; Weinstein, Harel; Fayad, Zahi A; Perez-Medina, Carlos; Mulder, Willem J M.
Augmenting drug-carrier compatibility improves tumour nanotherapy efficacy. Nature Communications 2016 ;Volum 7.
NTNU Untitled
 
2015
20 Hak, Sjoerd; Garaiova, Zuzana; Olsen, Linda Therese; Nilsen, Asbjørn Magne; Davies, Catharina De Lange.
The effects of oil-in-water nanoemulsion polyethylene glycol surface density on intracellular stability, pharmacokinetics, and biodistribution in tumor bearing mice. Pharmaceutical Research 2015 ;Volum 32.(4) s. 1475-1485
NTNU Untitled
 
21 Hak, Sjoerd; Goa, Pål Erik; Stenmark, Sebastian Tegnér; Bjerkholt, Frøydis F; Haraldseth, Olav.
Transverse relaxivity of iron oxide nanocrystals clustered in nanoemulsions: Experiment and theory. Magnetic Resonance in Medicine 2015 ;Volum 74.(3) s. 858-867
NTNU STO Untitled
 
22 Hak, Sjoerd; Åslund, Andreas K. O.; Zhao, Yiming; Mulder, Willem J.M.; Haraldseth, Olav; Davies, Catharina De Lange.
A fluorescence resonance energy transfer labeling method to study dissociation kinetics of lipid-based nanoparticles. World Molecular Imaging Conference; 2015-09-02 - 2015-09-05
NTNU Untitled
 
23 McDonagh, Birgitte Hjelmeland; Singh, Gurvinder; Hak, Sjoerd; Bandyopadhyay, Sulalit; Augestad, Ingrid Lovise; Sandvig, Ioanna; Sandvig, Axel; Glomm, Wilhelm.
L-DOPA-coated manganese oxide nanoparticles as dual MRI contrast agents and potential drug delivery vehicles. Nordic Neuroscience 2015; 2015-06-10 - 2015-06-12
NTNU Untitled
 
24 Mørch, Ýrr Asbjørg; Hansen, Rune; Berg, Sigrid; Åslund, Andreas; Glomm, Wilhelm; Eggen, Siv; Schmid, Ruth; Johnsen, Heidi; Kubowicz, Stephan; Snipstad, Sofie; Sulheim, Einar; Hak, Sjoerd; Singh, Gurvinder; McDonagh, Birgitte Hjelmeland; Blom, Hans; Davies, Ruth Catharina de Lange; Stenstad, Per Martin.
Nanoparticle-stabilized microbubbles for multimodal imaging and drug delivery. Contrast Media & Molecular Imaging 2015 ;Volum 10.(5) s. 356-366
NTNU SINTEF Untitled
 
25 Åslund, Andreas; Berg, Sigrid; Hak, Sjoerd; Mørch, Ýrr Asbjørg; Torp, Sverre Helge; Sandvig, Axel; Widerøe, Marius; Hansen, Rune; Davies, Ruth Catharina de Lange.
Nanoparticle delivery to the brain - By focused ultrasound and self-assembled nanoparticle-stabilized microbubbles. Journal of Controlled Release 2015 ;Volum 220. s. 287-294
NTNU SINTEF STO Untitled
 
2014
26 Hak, Sjoerd; Cebulla, Jana; Huuse, Else Marie; Davies, Catharina de Lange; Mulder, Willem J. M.; Larsson, Henrik; Haraldseth, Olav.
Periodicity in tumor vasculature targeting kinetics of ligand-functionalized nanoparticles studied by dynamic contrast enhanced magnetic resonance imaging and intravital microscopy. Angiogenesis 2014 ;Volum 17.(1) s. 93-107
NTNU STO Untitled
 
27 Hak, Sjoerd; Zuzana, Garaiova; Olsen, Linda Therese; Nilsen, Asbjørn Magne; Davies, Catharina De Lange.
The Effects of Oil-in-water Nanoemulsion Polyethylene Glycol Surface Density on Intracellular Stability, Pharmacokinetics, and Biodistribution in Tumor Bearing Mice. World Molecular Imaging Conference; 2014-09-17 - 2014-09-20
NTNU Untitled
 
28 Åslund, Andreas; Berg, Sigrid; Hak, Sjoerd; Mørch, Ýrr Asbjørg; Sandvig, Axel; Torp, Sverre Helge; Stenstad, Per Martin; Hansen, Rune; Glomm, Wilhelm; Davies, Catharina De Lange.
Delivery of multifunctional nanoparticles across the blood-brain barrier. The 2014 Joint National PhD Conference in Medical Imaging and MedViz Conference; 2014-06-17 - 2014-06-18
NTNU SINTEF Untitled
 
29 Åslund, Andreas; Berg, Sigrid; Hak, Sjoerd; Mørch, Ýrr Asbjørg; Torp, Sverre Helge; Sandvig, Axel; Widerøe, Marius; Stenstad, Per Martin; Hansen, Rune; Davies, Catharina De Lange.
Multifunctional nanoparticles for drug delivery across the blood-brain barrier. Biofysikkmøtet 2014; 2014-03-06 - 2014-03-07
NTNU SINTEF Untitled
 
30 Åslund, Andreas; Berg, Sigrid; Hak, Sjoerd; Mørch, Ýrr Asbjørg; Torp, Sverre Helge; Widerøe, Marius; Sandvig, Axel; Stenstad, Per Martin; Hansen, Rune; Davies, Catharina De Lange.
Nanoparticle-microbubbles and focused ultrasound to penetrate the blood-brain barrier. COST TD1004 Action: Theranostics Imaging and Therapy: An Action to Develop Novel Nanosized Systems for Imaging-Guided Drug Delivery; 2014-10-03 - 2014-10-04
NTNU SINTEF Untitled
 
2013
31 Garaiova, Zuzana; Hak, Sjoerd; Davies, Catharina De Lange; Hianik, Tibor.
Interaction of nanoparticles with biomembranes and lipid vesicles modified by artificial receptors. European Biophysics Journal 2013 ;Volum 42. s. S111-S111
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32 Hak, Sjoerd.
Improving nanoparticles for battling cancer.
NTNU Untitled
 
33 Hak, Sjoerd.
Targeted particles and polymers. World Molecular Imaging Conference; 2013-09-18 - 2013-09-21
NTNU Untitled
 
34 Hak, Sjoerd; Cebulla, Jana; Huuse, Else Marie; Davies, Catharina De Lange; Mulder, Willem J.M.; Larsson, Henrik BW; Haraldseth, Olav.
Tumor Targeting Kinetics of Ligand-Functionalized Nanoparticles Studied with Dynamic Contrast Enhanced Magnetic Resonance Imaging and Intravital Microscopy. World Molecular Imaging Conference; 2013-09-18 - 2013-09-21
NTNU Untitled
 
35 Zhao, Yiming; van Rooy, Inge; Hak, Sjoerd; Fay, Francois; Tang, Jun; Davies, Catharina De Lange; Skobe, Mihaela; Fisher, Edward Allen; Radu, Aurelian; Fayad, Zahi A; Donega, Celso de Mello; Meijerink, Andries; Mulder, Willem J.M..
Near-infrared fluorescence energy transfer imaging of nanoparticle accumulation and dissociation kinetics in tumor-bearing mice. ACS Nano 2013 ;Volum 7.(11) s. 10362-10370
NTNU Untitled
 
2012
36 Hak, Sjoerd; Helgesen, Emily; Hektoen, Helga; Huuse, Else Marie; Jarzyna, Peter A.; Mulder, Willem J.M.; Haraldseth, Olav; Davies, Catharina De Lange.
The Effect of Nanoparticle Polyethylene Glycol Surface Density on Ligand-Directed Tumor Targeting Studied in Vivo by Dual Modality Imaging. ACS Nano 2012 ;Volum 6.(6) s. 5648-5658
NTNU STO Untitled
 
2011
37 Hak, Sjoerd; Thuen, Marte; Jarzyna, Peter A.; Mulder, Willem J.M.; Syversen, Tore; Haraldseth, Olav; Davies, Catharina De Lange.
Combined in vivo confocal laser scanning microscopy and magnetic resonance imaging to study an αvβ3-integrin targeted nanoemulsion. International Society for Magnetic Resonance in Medicine; 2011-05-07
NTNU Untitled
 
38 Hak, Sjoerd; Emily, Helgesen; Hektoen, Helga H; Sæterbø, Kristin Grenstad; Marte, Thuen; Mulder, Willem J. M.; Haraldseth, Olav; Davies, Catharina De Lange.
Combined in vivo confocal laser scanning microscopy and magnetic resonance imaging to study an avb3-integrin targeted nanoemulsion. World Molecular Imaging Conference; 2011-09-10
NTNU Untitled
 
39 Hak, Sjoerd; Helgesen, Emily; Hektoen, Helga H; Sæterbø, Kristin Grendstad; Thuen, Marte; Mulder, Willem J. M.; Haraldseth, Olav; Davies, Catharina De Lange.
The effect of polyethylene glycol surface density on the targeting efficiency of αvβ3-integrin specific nanoparticles. PhD conference Norwegian Research School in Medical Imaging; 2011-11-20
NTNU UiO Untitled
 
2010
40 Hak, Sjoerd; Jarzyna, Peter A.; Mulder, Willem J.M.; Thuen, Marte; Reitan, Nina Kristine; Haraldseth, Olav; Davies, Catharina De Lange.
Combined in vivo MRI and in vivo CLSM to study the behavior of multifunctional nanoemulsions. World Molecular Imaging Conference; 2010-09-07 - 2010-09-10
NTNU Untitled
 
41 Hak, Sjoerd; Reitan, Nina Kristine; Haraldseth, Olav; Davies, Catharina De Lange.
Intravital microscopy in window chambers: a unique tool to study tumor angiogenesis and delivery of nanoparticles. Angiogenesis 2010 ;Volum 13.(2) s. 113-130
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2009
42 Hak, Sjoerd; Sanders, Erik H.M.; Agrawal, Prashant; Langereis, Sander; Grull, Holger; Keizer, Henk M.; Arena, Francesca; Terreno, Enzo; Strijkers, Gustav J.; Nicolay, Klaas.
A high relaxivity Gd(III)DOTA-DSPE-based liposomal contrast agent for magnetic resonance imaging. European journal of pharmaceutics and biopharmaceutics 2009 ;Volum 72. s. 397-404
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43 Kok, Maarten B.; Hak, Sjoerd; Mulder, Willem J.M.; van der Schaft, Daisy W.; Strijkers, Gustav J.; Nicolay, Klaas.
Cellular compartmentalization of internalized paramagnetic liposomes strongly influences both T1 and T2 relaxivity. Magnetic Resonance in Medicine 2009 ;Volum 61.(1022) Suppl. 1032
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44 Strijkers, Gustav J.; Hak, Sjoerd; Kok, Maarten B.; Springer, Charles; Nicolay, Klaas.
Three-compartment T1 relaxation model for intracellular paramagnetic contrast agents. Magnetic Resonance in Medicine 2009 ;Volum 61. s. 1049-1058
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2008
45 Mulder, Willem J.M.; Cormode, David P.; Hak, Sjoerd; Lobatto, Mark E.; Silvera, Stefano; Fayad, Zahi A.
Multimodality nanotracers for cardiovascular applications. Nature Clinical Practice Cardiovascular Medicine 2008 ;Volum 5. Suppl. 2 s. 103-111
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