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2023
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1. |
Hauge, Ingvild Hals; Sandegren, Vilde; Winther, Anja Ruud; Bøe, Cathrine Arnason; Salehian, Zhian; Håvarstein, Leiv Sigve; Kjos, Morten; Straume, Daniel. A novel proteinaceous molecule produced by Lysinibacillus sp. OF-1 depends on the Ami oligopeptide transporter to kill Streptococcus pneumoniae. Microbiology (Reading) 2023 ;Volum 169.(3) NMBU VETINST
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2. |
Minhas, Vikrant; Domenech, Arnau; Synefiaridou, Dimitra; Straume, Daniel; Brendel, Max; Cebrero, Gonzalo; Liu, Xue; Costa, Charlotte; Baldry, Mara; Sirard, Jean-Claude; Perez, Camilo; Gisch, Nicolas; Hammerschmidt, Sven; Håvarstein, Leiv Sigve; Veening, Jan-Willem. Competence remodels the pneumococcal cell wall exposing key surface virulence factors that mediate increased host adherence. PLoS Biology 2023 ;Volum 21.(1) NMBU
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2021
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3. |
Bodin, Johanna Eva; Thorstensen, Tage; Alsheikh, Muath K; Basic, Dean; Edvardsen, Rolf Brudvik; Dalen, Knut Tomas; Duale, Nur; Eklo, Ole Martin; Ergon, Åshild Gunilla; Jevnaker, Anne-Marthe Ganes; Hindar, Kjetil; Håvarstein, Leiv Sigve; Malmstrøm, Martin; Nielsen, Kaare Magne; Olsen, Siri Lie; Rueness, Eli Knispel; Sanden, Monica; Sipinen, Ville Erling; von Krogh, Kristine; Våge, Dag Inge; Wargelius, Anna; Wendell, Per Hans Micael; Yazdankhah, Siamak Pour; Alexander, Jan; Bruzell, Ellen Merete; Hemre, Gro Ingunn; Vandvik, Vigdis; Agdestein, Angelika; Elvevoll, Edel O.; Hessen, Dag Olav; Hofshagen, Merete; Husøy, Trine; Knutsen, Helle Katrine; Krogdahl, Åshild; Nilsen, Asbjørn Magne; Rafoss, Trond; Skjerdal, Olaug Taran; Steffensen, Inger-Lise Karin; Strand, Tor Arne; Velle, Gaute; Wasteson, Yngvild. Genome editing in food and feed production – implications for risk assessment. Scientific Opinion of the Scientific Steering Committee of the Norwegian Scientific Committee for Food and Environment. VKM Report 2021 ;Volum 2021.(18) s. - NMBU FHI UiO NINA HAVFORSK OSLOMET VETINST SI UiT UiB NTNU NIOM NIBIO NORCE
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4. |
Myrbråten, Ine Storaker. Functional insights into novel factors affecting cell division in Gram-positive bacteria. : KBM/NMBU 2021 248 s. Philosophiae Doctor (PhD) Thesis(2021:91) NMBU
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5. |
Straume, Daniel; Piechowiak, Katarzyna Wiaroslawa; Kjos, Morten; Håvarstein, Leiv Sigve. Class A PBPs: it is time to rethink traditional paradigms. Molecular Microbiology 2021 ;Volum 116.(1) s. 41-52 NMBU
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6. |
Winther, Anja Ruud; Kjos, Morten; Herigstad, Marie Leangen; Håvarstein, Leiv Sigve; Straume, Daniel. EloR Interacts with the Lytic Transglycosylase MltG at Midcell in Streptococcus pneumoniae R6. Journal of Bacteriology 2021 ;Volum 203.(9) s. - NMBU
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2020
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7. |
Alcorlo, Martín; Straume, Daniel; Lutkenhaus, Joe; Håvarstein, Leiv Sigve; Hermoso, Juan A.. Structural characterization of the essential cell division protein ftse and its interaction with ftsx in streptococcus pneumoniae. mBio 2020 NMBU
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8. |
Stamsås, Gro Anita; Restelli, Marine; Ducret, A; Freton, Celine; Garcia, Pierre Simon; Håvarstein, Leiv Sigve; Straume, Daniel; Grangeasse, Christophe; Kjos, Morten. A CozE Homolog Contributes to Cell Size Homeostasis of Streptococcus pneumoniae. mBio 2020 ;Volum 11.(5) NMBU
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9. |
Straume, Daniel; Piechowiak, Katarzyna Wiaroslawa; Olsen, Silje Janette Bredholt; Stamsås, Gro Anita; Berg, Kari Helene; Kjos, Morten; Heggenhougen, Maria Victoria; Alcorlo, Martín; Hermoso, Juan A.; Håvarstein, Leiv Sigve. Class A PBPs have a distinct and unique role in the construction of the pneumococcal cell wall.. Proceedings of the National Academy of Sciences of the United States of America 2020 ;Volum 117.(11) s. 6129-6138 NMBU
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2019
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10. |
Kjos, Morten; Straume, Daniel; Håvarstein, Leiv Sigve. Derfor klarer vi ikke å utrydde pneumokokkinfeksjoner.. Aftenposten Viten 2019 s. 20-21 NMBU
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11. |
Myrbråten, Ine Storaker; Stamsås, Gro Anita; Chan, Helena; Håvarstein, Leiv Sigve; Kjos, Morten. A cell splitting control protein identified by a localization screen of essential staphylococcal genes. EMBO Workshop. Bacterial cell division: Closing the gap; 2019-06-09 - 2019-06-12 NMBU
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12. |
Myrbråten, Ine Storaker; Stamsås, Gro; Håvarstein, Leiv Sigve; Kjos, Morten. Identification of a novel cell splitting control protein in Staphylococcus aureus. EMBO/EMBL Symposium: New Approaches and Concepts in Microbiology; 2019-07-09 - 2019-09-13 NMBU
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13. |
Myrbråten, Ine Storaker; Wiull, Kamilla; Salehian, Zhian; Håvarstein, Leiv Sigve; Straume, Daniel; Mathiesen, Geir; Kjos, Morten. CRISPR Interference for Rapid Knockdown of Essential Cell Cycle Genes in Lactobacillus plantarum. mSphere 2019 ;Volum 4.(2) NMBU
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14. |
Rued, Britta E.; Alcorlo, Martín; Edmonds, Katherine A.; Martínez-Caballero, Siseth; Straume, Daniel; Fu, Yue; Bruce, Kevin E.; Wu, Hongwei; Håvarstein, Leiv Sigve; Hermoso, Juan A.; Winkler, Malcom E.; Giedroc, David P.. Structure of the Large Extracellular Loop of FtsX and Its Interaction with the Essential Peptidoglycan Hydrolase PcsB in Streptococcus pneumoniae. mBio 2019 ;Volum 10.(1) NMBU
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15. |
Schmidt, Frank; Kakar, Niamatullah; Meyer, Tanja; Depke, Maren; Masouris, Ilias; Burchhardt, Gerhard; Gómez-Mejia, Alejandro; Dhople, Vishnu; Håvarstein, Leiv Sigve; Sun, Zhi; Moritz, Robert L.; Völker, Uwe; Koedel, Uwe; Hammerschmidt, Sven. In vivo proteomics identifies the competence regulon and AliB oligopeptide transporter as pathogenic factors in pneumococcal meningitis. PLoS Pathogens 2019 ;Volum 15:e1007987.(7) s. 1-28 NMBU
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16. |
Stamsås, Gro Anita; Straume, Daniel; Håvarstein, Leiv Sigve; Kjos, Morten. Evidence for that the pneumococcal CozE-homolog CelP affects functionality of penicillin binding protein 1a. Europneumo 2019; 2019-06-11 - 2019-06-14 NMBU
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17. |
Winther, Anja Ruud; Kjos, Morten; Stamsås, Gro Anita; Håvarstein, Leiv Sigve; Straume, Daniel. Prevention of EloR/KhpA heterodimerization by introduction of site-specific amino acid substitutions renders the essential elongasome protein PBP2b redundant in Streptococcus pneumoniae. Scientific Reports 2019 ;Volum 9.(3681) s. 1-13 NMBU
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2018
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18. |
Bonnet, Julie; Mortier-Barrière, Isabelle; Campo, Nathalie; Jacq, Maxime; Moriscot, Christine; Straume, Daniel; Berg, Kari Helene; Håvarstein, Leiv Sigve; Wong, Yung-Sing; Vernet, Thierry; Di Guilmi, Anne Marie. Nascent teichoic acids insertion into the cell wall directs the localization and activity of the major pneumococcal autolysin LytA.. The Cell Surface 2018 ;Volum 2. s. 24-37 NMBU
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19. |
Morlot, Cécile; Straume, Daniel; Peters, Katharina; Hegnar, Olav Aaseth; Simon, Nolwenn; Villard, Anne-Maria; Contreras-Martel, Carlos; Leisico, Francisco; Breukink, Eefjan; Gravier-Pelletier, Christine; Le Corre, Laurent; Vollmer, Waldemar; Pietrancosta, Nicolas; Håvarstein, Leiv Sigve; Zapun, André. Structure of the essential peptidoglycan amidotransferase MurT/GatD complex from Streptococcus pneumoniae. Nature Communications 2018 ;Volum 9:3180. s. 1-12 NMBU
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20. |
Myrbråten, Ine; Stamsås, Gro; Salehian, Zhian; Håvarstein, Leiv Sigve; Kjos, Morten. Localization screening of unknown essential proteins in Staphylococcus aureus. International Symposium on Staphylococci and Staphylococcal Infections; 2018-08-23 - 2018-08-26 NMBU
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21. |
Stamsås, Gro; Myrbråten, Ine; Salehian, Zhian; Veening, Jan-Willem; Håvarstein, Leiv Sigve; Kjos, Morten. CRISPR interference (CRISPRi) system used for gene depletion in Staphylococcus aureus. International Symposium on Staphylococci and Staphylococcal Infections; 2018-08-23 - 2018-08-26 NMBU
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22. |
Stamsås, Gro; Myrbråten, Ine; Straume, Daniel; Salehian, Zhian; Veening, Jan-Willem; Håvarstein, Leiv Sigve; Kjos, Morten. Cell division coordination in Staphylococcus aureus by membrane proteins CozEa and CozEb. International Symposium on Staphylococci and Staphylococcal Infections; 2018-08-23 - 2018-08-26 NMBU
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23. |
Stamsås, Gro; Myrbråten, Ine; Straume, Daniel; Salehian, Zhian; Veening, Jan-Willem; Håvarstein, Leiv Sigve; Kjos, Morten. CozEa and CozEb play overlapping and essential roles in controlling cell division in Staphylococcus aureus. Molecular Microbiology 2018 ;Volum 12.(10) s. 2363-2375 NMBU
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2017
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24. |
Håvarstein, Leiv Sigve. Natural transformation in Streptococci: pheromones and fratricins.. 13th European meeting on the molecular biology of the pneumococcus.; 2017-06-27 - 2017-06-30 NMBU
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25. |
Salehian, Zhian; Myrbråten, Ine; Stamsås, Gro; Veening, Jan-Willem; Håvarstein, Leiv Sigve; Kjos, Morten. Gene depletion in Staphylococcus aureus by CRISPR depletion. New Approaches and Concepts in Microbiology; 2017-06-27 - 2017-06-30 NMBU
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26. |
Stamsås, Gro; Straume, Daniel; Salehian, Zhian; Håvarstein, Leiv Sigve. Evidence that pneumococcal WalK is regulated by StkP through protein-protein interaction.. Microbiology (Reading) 2017 ;Volum 163.(3) s. 383-399 NMBU
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27. |
Stamsås, Gro; Straume, Daniel; Winther, Anja Ruud; Kjos, Morten; Frantzen, Cyril Alexander; Håvarstein, Leiv Sigve. Identification of EloR (Spr1851) as a regulator of cell elongation in Streptococcus pneumoniae.. Molecular Microbiology 2017 ;Volum 105.(6) s. 954-967 NMBU
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28. |
Straume, Daniel; Stamsås, Gro Anita; Salehian, Zhian; Håvarstein, Leiv Sigve. Overexpression of the fratricide immunity protein ComM leads to growth inhibition and morphological abnormalities in Streptococcus pneumoniae. Microbiology (Reading) 2017 ;Volum 163.(1) s. 9-21 NMBU
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29. |
Straume, Daniel; Stamsås, Gro; Berg, Kari Helene; Salehian, Zhian; Håvarstein, Leiv Sigve. Identification of pneumococcal proteins that are functionally linked to penicillin-binding protein 2b (PBP2b).. Molecular Microbiology 2017 ;Volum 103.(1) s. 99-116 NMBU
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30. |
Straume, Daniel; Stamsås, Gro; Ruud Winther, Anja; Kjos, Morten; Frantzen, Cyril A; Håvarstein, Leiv Sigve. Identification of EloR (Spr1851) as a regulator of cell elongation in Streptococcus pneumoniae. 13th European Meeting on the Molecular Biology of the Pneumococcus; 2017-07-27 - 2017-07-30 NMBU
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31. |
Straume, Daniel; Stamsås, Gro; Winther, Anja Ruud; Kjos, Morten; Frantzen, Cyril A; Håvarstein, Leiv Sigve. Identification of EloR (Spr1851) as a regulator of cell elongation in Streptococcus pneumoniae. Federation of European Biochemical Societies Congress 2017; 2017-09-10 NMBU
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32. |
Winther, Anja Ruud; Straume, Daniel; Stamsås, Gro; Håvarstein, Leiv Sigve. Supressor mutations in mreC reduce the elongasome activity. 13th European Meeting on the Molecular Biology of the Pneumococcus; 2017-06-27 - 2017-06-30 NMBU
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2015
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33. |
Håvarstein, Leiv Sigve. Antibiotikaresistens hos Streptococcus pneumoniae. Bakterier og antibiotikaresistens; 2015-03-06 - 2015-03-06 NMBU
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34. |
Straume, Daniel; Berg, Kari Helene; Stamsås, Gro; Håvarstein, Leiv Sigve. PBP2b, MreD and DivIVA constitute a functional unit in the peripheral peptidoglycan synthesis machinery of Streptococcus pneumoniae. 12th European Meeting on the Molecular Biology of the Pneumococcus; 2015-07-07 - 2015-07-10 NMBU
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35. |
Straume, Daniel; Stamsås, Gro Anita; Håvarstein, Leiv Sigve. Natural transformation and genome evolution in Streptococcus pneumoniae. Infection, Genetics and Evolution 2015 ;Volum 33. s. 371-380 NMBU
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2014
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36. |
Bartual, Sergio Galan; Straume, Daniel; Stamsås, Gro Anita; Munoz, Ines G; Alfonso, Carlos; Martinez-Ripoll, Martin; Håvarstein, Leiv Sigve; Hermoso, Juan. Structural basis of PcsB-mediated cell separation in streptococcus pneumoniae. Nature Communications 2014 ;Volum 5. NMBU
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37. |
Berg, Kari Helene; Straume, Daniel; Håvarstein, Leiv Sigve. The function of the transmembrane and cytoplasmic domains of pneumococcal penicillin-binding proteins 2x and 2b extends beyond that of simple anchoring devices. Microbiology (Reading) 2014 ;Volum 160.(8) s. 1585-1598 NMBU
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38. |
Fagerlund, Annette; Granum, Per Einar; Håvarstein, Leiv Sigve. Staphylococcus aureus competence genes: Mapping of the SigH, ComK1 and ComK2 regulons by transcriptome sequencing. Molecular Microbiology 2014 ;Volum 94.(3) s. 557-579 NMBU
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2013
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39. |
Berg, Kari Helene; Stamsås, Gro Anita; Straume, Daniel; Håvarstein, Leiv Sigve. Effects of low Pbp2b levels on cell morphology and peptidoglycan composition in Streptococcus pneumoniae. TRAP-meeting (Competence, transformation and their biological consequences in the pneumococcus); 2013-08-19 - 2013-08-22 NMBU
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40. |
Berg, Kari Helene; Stamsås, Gro Anita; Straume, Daniel; Håvarstein, Leiv Sigve. Effects of Low PBP2b Levels on Cell Morphology and Peptidoglycan Composition in Streptococcus pneumoniae R6. Journal of Bacteriology 2013 ;Volum 195.(19) s. 4342-4354 NMBU
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41. |
Berg, Kari Helene; Stamsås, Gro Anita; Straume, Daniel; Håvarstein, Leiv Sigve. The effect of low Pbp2b levels on cell morphology and peptidoglycan composition in Streptococcus pneumoniae. EuroPneumo 2013, XI European Meeting on the Molecular Biology of the Pneumococcus.; 2013-05-28 - 2013-05-31 NMBU
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42. |
Fagerlund, Annette; Granum, Per Einar; Håvarstein, Leiv Sigve. A limited subset of late competence genes is controlled by Staphylococcus aureus SigH. The 3rd Norwegian Microbiology Meeting; 2013-11-14 - 2013-11-16 NMBU
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43. |
Håvarstein, Leiv Sigve. Fratricide - a mechanism used by naturally transformable streptococci to get access to homologous DNA during the competent state. Invitert foredrag; 2013-09-06 - 2013-09-06 NMBU
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44. |
Håvarstein, Leiv Sigve. Fratricide in the genus Streptococcus. GMM4, 4th microbial genome maintenance meeting : transformation and DNA repair.; 2013-04-26 - 2013-04-29 NMBU
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45. |
Stamsås, Gro Anita; Håvarstein, Leiv Sigve; Straume, Daniel. CHiC, a new tandem affinity tag for the protein purification toolbox. Journal of Microbiological Methods 2013 ;Volum 92.(1) s. 59-63 NMBU
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46. |
Stamsås, Gro Anita; Straume, Daniel; Berg, Kari Helene; Håvarstein, Leiv Sigve. Rapid intramembrane proteolysis prevents accumulation of toxic levels of the fratricide-immunity protein ComM. Europneumo 2013; 2013-05-28 - 2013-05-31 NMBU
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47. |
Straume, Daniel; Stamsås, Gro Anita; Berg, Kari Helene; Håvarstein, Leiv Sigve. Evidence that rapid intramembrane proteolysis prevents accumulation of toxic levels of the fratricide-immunity protein ComM. TRAP 2013, Competence, Transformation and Their Biological Consequences in the Pneumococcus.; 2013-08-19 - 2013-08-22 NMBU
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2012
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48. |
Berg, Kari Helene; Biørnstad, Truls Johan; Johnsborg, Ola; Håvarstein, Leiv Sigve. Properties and Biological Role of Streptococcal Fratricins. Applied and Environmental Microbiology 2012 ;Volum 78.(10) s. 3515-3522 NMBU
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49. |
Berg, Kari Helene; Ohnstad, Hilde Solheim; Håvarstein, Leiv Sigve. LytF, a Novel Competence-Regulated Murein Hydrolase in the Genus Streptococcus. Journal of Bacteriology 2012 ;Volum 194.(3) s. 627-635 NMBU
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50. |
Biørnstad, Truls Johan; Ohnstad, Hilde Solheim; Håvarstein, Leiv Sigve. Deletion of the murein hydrolase CbpD reduces transformation efficiency in Streptococcus thermophilus. Microbiology (Reading) 2012 ;Volum 158.(4) s. 877-885 NMBU
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