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2019
1 Svendsen, John Sigurd Mjøen; Grant, Thomas M; Rennison, David; Brimble, Margaret A.; Svenson, Johan.
Very Short and Stable Lactoferricin-Derived Antimicrobial Peptides: Design Principles and Potential Uses. Accounts of Chemical Research 2019 ;Volum 52.(3) s. 749-759
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2018
2 Johansen, Finn-Eirik; Brautaset, Trygve; Aune, Marie Hjelmseth; Patriksson, Alexandra; Falkenberg, Liv Eggset; Kleppe, Rune; Dick, Gunnar; Strand, Berit Løkensgard; Eijsink, Vincent; Røyne, Anja; Goksøyr, Anders; Svendsen, John Sigurd Mjøen; Fyhn, Marianne; Vik, Jon Olav; Wentzel, Alexander; Aksnes, Astrid; Bruheim, Per; Carlsen, Sven Magnus; Åm, Heidrun.
Centre for Digital Life Norway - Annual report 2017. : Senter for Digialt Liv Norge 2018 35 s.
NTNU SINTEF UiB UiO UiT NMBU Untitled
 
3 Svendsen, John Sigurd Mjøen.
Hva betyr antibiotikakrisen for kreftpasienter. Mye Kreftforeningens distriktskontor i Tromsø og Hamar; 2018-04-03 - 2018-04-03
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4 Svendsen, John Sigurd Mjøen.
Panel: Are new antibiotics the solution to the AMR threat?. 37 degree conference; 2018-06-19 - 2018-06-20
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5 Svendsen, John Sigurd Mjøen.
Paneldebatt: Antibiotikaresistens og kreft. Paneldebatt; 2018-04-25
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6 Thakkar, Balmukund; Svendsen, John Sigurd Mjøen; Engh, Richard Alan.
Density Functional Studies on Secondary Amides: Role of Steric Factors in Cis/Trans Isomerization. Molecules 2018 ;Volum 23. s. -
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2017
7 Thakkar, Balmukund; Albrigtsen, Marte; Svendsen, John Sigurd Mjøen; Andersen, Jeanette hammer; Engh, Richard Alan.
Biofocussed chemoprospecting: An efficient approach for drug discovery. Chemical Biology and Drug Design 2017 ;Volum 90.(1) s. 128-140
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8 Thakkar, Balmukund; Svendsen, John Sigurd Mjøen; Engh, Richard Alan.
Cis/Trans Isomerization in Secondary Amides: Reaction Paths, Nitrogen Inversion and Relevance to Peptidic Systems. Journal of Physical Chemistry A 2017 ;Volum 121.(36) s. 6830-6837
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2016
9 Eksteen, Jacobus Johannes; Ausbacher, Dominik; Simon-Santamaria, Jaione; Stiberg, Trine; Cavalcanti Jacobsen, Cristiane de Albuquerque; Wushur, Imin; Svendsen, John Sigurd Mjøen; Rekdal, Øystein.
Iterative design and in vivo evaluation of an oncolytic antilymphoma peptide. Journal of Medicinal Chemistry 2016 ;Volum 60.(1) s. 146-156
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10 Haug, Bengt Erik; Camilio, Ketil Andre; Eliassen, liv tone; Stensen, Wenche; Svendsen, John Sigurd Mjøen; Berg, Kristel; Mortensen, Bjarte; Serin, Guillaume; Mirjolet, Jean-Francois; Bichat, Francis; Rekdal, Øystein.
Discovery of a 9-mer cationic peptide (LTX-315) as a potential first in class oncolytic peptide. Journal of Medicinal Chemistry 2016 ;Volum 59.(7) s. 2918-2927
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11 Rothweiler, Ulli; Stensen, Wenche; Brandsdal, Bjørn Olav; Isaksson, Johan; Leeson, Frederick Alan; Engh, Richard Alan; Svendsen, John Sigurd Mjøen.
Probing the ATP-Binding Pocket of Protein Kinase DYRK1A with Benzothiazole Fragment Molecules. Journal of Medicinal Chemistry 2016 ;Volum 59.(21) s. 9814-9824
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12 Stensen, Wenche; Turner, Rob; Brown, Marc; Kondori, Nahid; Svendsen, John Sigurd Mjøen; Svenson, Johan.
Short Cationic Antimicrobial Peptides Display Superior Antifungal Activities toward Candidiasis and Onychomycosis in Comparison with Terbinafine and Amorolfine. Molecular Pharmaceutics 2016 ;Volum 13.(10) s. 3595-3600
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2015
13 Rothweiler, Ulli; Eriksson, Jonas; Stensen, Wenche; Leeson, Frederick Alan; Engh, Richard Alan; Svendsen, John Sigurd.
Luciferin and derivatives as a DYRK selective scaffold for the design of protein kinase inhibitors. European Journal of Medicinal Chemistry 2015 ;Volum 94. s. 140-148
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2014
14 Alsos, Inger Greve; Ekrem, Torbjørn; Svendsen, John Sigurd.
- Kan bidra til utviklingen av nye medisiner. NRK Troms og Finnmark [Internett] 2014-03-13
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15 Alsos, Inger Greve; Ekrem, Torbjørn; Svendsen, John Sigurd.
DNA fra planter og dyr kan gi kunnskap om sykdommer. NRK Nordnytt og NRK Morgennytt [TV] 2014-03-13
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16 Alsos, Inger Greve; Ekrem, Torbjørn; Svendsen, John Sigurd.
Lager digitalt oppslagsverk over alt liv på jorda. NRK Her og nå, P1 [Radio] 2014-03-13
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17 Gozhina, Olga Vladimirovna; Svendsen, John Sigurd; Lejon, Tore.
Synthesis and antimicrobial activity of α-aminoboronic-containing peptidomimetics. Journal of Peptide Science 2014 ;Volum 20.(1) s. 20-24
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18 Hellio, Claire; Pavia, Henrik; Haug, Tor; Stensen, Wenche; Stensvåg, Klara; Svendsen, John Sigurd; Svenson, Johan.
Antifouling compounds from the sub-Arctic ascidian Synoicum pulmonaria. 17th International Congress on Marine Corrosion and Fouling (ICMCF); 2014-07-06 - 2014-07-10
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19 Sivertsen, Annfrid; Isaksson, Johan; Leiros, Hanna-Kirsti S.; Svenson, Johan; Svendsen, John Sigurd; Brandsdal, Bjørn Olav.
Synthetic cationic antimicrobial peptides bind with their hydrophobic parts to drug site II of human serum albumin. BMC Structural Biology 2014 ;Volum 14:4.
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20 Trepos, Rozenn; Cervin, Gunnar; Hellio, Claire; Pavia Henrik, Henrik; Stensen, Wenche; Stensvåg, Klara; Svendsen, John Sigurd; Haug, Tor; Svenson, Johan.
Antifouling compounds from the sub-arctic ascidian synoicum pulmonaria: Synoxazolidinones A and C, pulmonarins A and B, and synthetic analogues. Journal of natural products 2014 ;Volum 77.(9) s. 2105-2113
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2013
21 Demissie, Taye B.; Repisky, Michal; Komorovsky, Stanislav; Isaksson, Johan; Svendsen, John Sigurd; Dodziuk, H; Ruud, Kenneth.
Four-component relativistic chemical shift calculations of halogenated organic compounds. Journal of Physical Organic Chemistry 2013 ;Volum 26.(8) s. 679-687
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22 Hanssen, Kine Ø.; Schuler, Bruno; Williams, Antony J.; Demissie, Taye B.; Hansen, Espen; Andersen, Jeanette hammer; Svenson, Johan; Svendsen, John Sigurd; Gross, Leo; Jaspars, Marcel; Isaksson, Johan.
Introducing Atomic Force Microscopy in Structure Elucidation. SMASH 2013; 2013-09-22 - 2013-09-25
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23 Gorovoy, Alexey Sergeevich; Gozhina, Olga Vladimirovna; Svendsen, John Sigurd; Domorad, Anna A.; Tetz, Victor V.; Tetz, George V.; Lejon, Tore.
Boron containing peptidomimetics – a novel class of selective anti-tubercular drugs. Chemical Biology and Drug Design 2013 ;Volum 81.(3) s. 408-413
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24 Gorovoy, Alexey Sergeevich; Gozhina, Olga Vladimirovna; Svendsen, John Sigurd; Tetz, George V.; Domorad, Anna A.; Tetz, Victor V.; Lejon, Tore.
Syntheses and anti-tubercular activity of β-substituted and α,β-disubstituted peptidyl β-aminoboronates and boronic acids. Journal of Peptide Science 2013 ;Volum 19.(10) s. 613-618
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25 Li, Xiaojun; Hopmann, Kathrin Helen; Hudecova, Jana; Isaksson, Johan; Novotná, Jana; Stensen, Wenche; Andrushchenko, Valery; Urbanová, Marie; Svendsen, John Sigurd; Bour, Petr; Ruud, Kenneth.
Determination of Absolute Configuration and Conformation of a Cyclic Dipeptide by NMR and Chiral Spectroscopic Methods. Journal of Physical Chemistry A 2013 ;Volum 117.(8) s. 1721-1736
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26 Sivertsen, Annfrid; Brandsdal, Bjørn Olav; Svendsen, John Sigurd; Andersen, Jeanette hammer; Svenson, Johan.
Short cationic antimicrobial peptides bind to human alpha-1 acid glycoprotein with no implications for the in vitro bioactivity. Journal of Molecular Recognition 2013 ;Volum 26.(10) s. 461-469
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27 Thakkar, Balmukund; Svendsen, John Sigurd Mjøen; Engh, Richard Alan.
Design and Synthesis of diverse Piperazine-2,5-diones and their uncyclized analogues as potential kinase inhibitors. BioStruct open day seminar; 2013-05-08 - 2013-05-08
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2012
28 Østnes Hanssen, Kine; Schuler, Bruno; Williams, Antony J.; Demissie, Taye B.; Hansen, Espen; Andersen, Jeanette hammer; Svenson, Johan; Blinov, Kirill; Repisky, Michal; Mohn, Fabian; Meyer, Gerhard; Svendsen, John Sigurd; Ruud, Kenneth; Elyashberg, Mikhail; Gross, Leo; Jaspars, Marcel; Isaksson, Johan.
A Combined Atomic Force Microscopy and Computational Approach for the Structural Elucidation of Breitfussin A and B: Highly Modified Halogenated Dipeptides from Thuiaria breitfussi. Angewandte Chemie International Edition 2012 ;Volum 51.(49) s. 12238-12241
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29 Hopmann, Kathrin Helen; Šebestík, Jaroslav; Novotná, Jana; Stensen, Wenche; Urbanová, Marie; Svenson, Johan; Svendsen, John Sigurd; Bour, Petr; Ruud, Kenneth.
Determining the Absolute Configuration of Two Marine Compounds Using Vibrational Chiroptical Spectroscopy. Journal of Organic Chemistry 2012 ;Volum 77.(2) s. 858-869
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30 Karstad, Rasmus Tørnes; Isaksen, Geir Villy; Wynendaele, Evelien; Guttormsen, Yngve; De Spiegeleer, Bart; Brandsdal, Bjørn Olav; Svendsen, John Sigurd; Svenson, Johan.
Targeting the S1 and S3 Subsite of Trypsin with Unnatural Cationic Amino Acids Generates Antimicrobial Peptides with Potential for Oral Administration. Journal of Medicinal Chemistry 2012 ;Volum 55.(14) s. 6294-6305
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31 Li, Xiaojun; Hopmann, Kathrin Helen; Hudecova, Jana; Stensen, Wenche; Novotná, Jana; Urbanová, Marie; Svendsen, John Sigurd; Bour, Petr; Ruud, Kenneth.
Absolute Configuration of a Cyclic Dipeptide Reflected in Vibrational Optical Activity: Ab Initio and Experimental Investigation. Journal of Physical Chemistry A 2012 ;Volum 116.(10) s. 2554-2563
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2011
32 Avenarius, Derk; Svendsen, John Sigurd; Malm, Dag.
Proton nuclear magnetic resonance spectroscopic detection of oligomannosidic n glycans in alpha-mannosidosis: a method of monitoring treatment. Journal of Inherited Metabolic Disease 2011 ;Volum 34.(5) s. 1023-1027
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33 Flaten, Gøril Eide; Kottra, Gabor; Stensen, Wenche; Isaksen, Geir Villy; Karstad, Rasmus Tørnes; Svendsen, John Sigurd; Daniel, Hannelore; Svenson, Johan.
In Vitro Characterization of Human Peptide Transporter hPEPT1 Interactions and Passive Permeation Studies of Short Cationic Antimicrobial Peptides. Journal of Medicinal Chemistry 2011 ;Volum 54.(7) s. 2422-2432
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34 Isaksen, Geir Villy; Isaksson, Johan; Svendsen, John Sigurd; Brandsdal, Bjørn Olav.
Structural studies of small cationic antimicrobial peptides by NMR and computer simulations have facilitated a refined pharmacophore model able to predict activity versus Staphylococcus aureus. SMASH 2011; 2011-09-18 - 2011-09-21
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35 Isaksson, Johan; Brandsdal, Bjørn Olav; Engqvist, Stig Olov Magnus; Flaten, Gøril Eide; Svendsen, John Sigurd; Stensen, Wenche.
A Synthetic Antimicrobial Peptidomimetic (LTX 109): Stereochemical Impact on Membrane Disruption. Journal of Medicinal Chemistry 2011 ;Volum 54.(16) s. 5786-5795
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2010
36 Isaksen, Geir Villy; Karstad, Rasmus Tørnes; Isaksson, Johan Mattias; Svenson, Johan; Svendsen, John Sigurd; Brandsdal, Bjørn Olav.
Structure of short cationic antimicrobial peptides and their interactions with membranes as revealed by MD simulations. ISB Winter School 2010; 2010-12-07 - 2010-12-10
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37 Isaksson, Johan; Flaten, Gøril Eide; Brandsdal, Bjørn Olav; Svendsen, John Sigurd.
Studies of Small Synthetic Anti-microbial Peptides by NMR and Molecular Modeling. Joint EUROMAR 2010 + ISMAR 2010; 2010-07-05 - 2010-07-09
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38 Karstad, Rasmus Tørnes; Isaksen, Geir; Brandsdal, Bjørn Olav; Svendsen, John Sigurd; Svenson, Johan.
Unnatural Amino Acid Side Chains as S1, S1 ', and S2 ' Probes Yield Cationic Antimicrobial Peptides with Stability toward Chymotryptic Degradation. Journal of Medicinal Chemistry 2010 ;Volum 53.(15) s. 5558-5566
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39 Svenson, Johan; Vergote, V; Karstad, Rasmus Tørnes; Burvenich, C; Svendsen, John Sigurd; De Spiegeleer, B.
Metabolic Fate of Lactoferricin-Based Antimicrobial Peptides: Effect of Truncation and Incorporation of Amino Acid Analogs on the In Vitro Metabolic Stability. Journal of Pharmacology and Experimental Therapeutics 2010 ;Volum 332.(3) s. 1032-1039
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2009
40 Flemming, Kristina; Klingenberg, Claus; Cavanagh, Jorunn Pauline; Sletteng, Merethe vibeke; Stensen, Wenche; Svendsen, John Sigurd; Flaegstad, Trond.
High in vitro antimicrobial activity of synthetic antimicrobial peptidomimetics against staphylococcal biofilms. Journal of Antimicrobial Chemotherapy 2009 ;Volum 63.(1) s. 136-145
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41 Svenson, Johan; Karstad, Rasmus Tørnes; Flaten, Gøril Eide; Brandsdal, Bjørn Olav; Brandl, Martin; Svendsen, John Sigurd.
Altered Activity and Physicochemical Properties of Short Cationic Antimicrobial Peptides by Incorporation of Arginine Analogues. Molecular Pharmaceutics 2009 ;Volum 6.(3) s. 996-1005
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2008
42 Haug, Bengt Erik; Stensen, Wenche; Kalaaji, manar; Rekdal, Øystein; Svendsen, John Sigurd.
Synthetic antimicrobial peptidomimetics with therapeutic potential. Journal of Medicinal Chemistry 2008 ;Volum 51. s. 4306-4314
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43 Svenson, Johan Karl; Stensen, Wenche; Brandsdal, Bjørn Olav; Haug, Bengt Erik; Monrad, Johnny; Svendsen, John Sigurd.
Antimicrobial Peptides with Stability toward Tryptic Degradation. Biochemistry 2008 ;Volum 47.(12) s. 3777-3788
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2007
44 Haug, Bengt Erik; Stensen, Wenche; Svendsen, John Sigurd.
Application of the Suzuki-Miyaura cross-coupling to increase antimicrobial potency generates promising novel antibacterials. Bioorganic & Medicinal Chemistry Letters 2007 ;Volum 17.
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45 Haug, Bengt Erik; Strøm, Morten B.; Svendsen, John Sigurd.
The medicinal chemistry of short lactoferricin-based antibacterial peptides. Current Medicinal Chemistry 2007 ;Volum 14.(1) s. 1-18
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46 Svendsen, John Sigurd.
Diversity from the high arctic. Pacific Rim Summit on Biotechnology and Biofuels; 2007-11-14 - 2007-11-16
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47 Svenson, Johan Karl; Brandsdal, Bjørn Olav; Stensen, Wenche; Svendsen, John Sigurd.
Albumin binding of short cationic antimicrobial micropeptides and its influence on the in vitro bactericidal effect. Journal of Medicinal Chemistry 2007 ;Volum 50. s. -
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2006
48 Jing, WG; Svendsen, John Sigurd; Vogel, HJ.
Comparison of NMR structures and model-membrane interactions of 15-residue antimicrobial peptides derived from bovine lactoferricin. Biochemistry and Cell Biology 2006 ;Volum 84. s. 312-326
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2005
49 Avenarius, JS; Svendsen, John Sigurd; Malm, Dag.
Proton nuclear magnetic resonance spectroscopic detection of oligomannosidic N glycans in alpha-mannosidosis: A method of monitoring treatment?. Book of abstract 2005
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50 Benach, J; Winberg, Jan-Olof; Svendsen, John sigurd; Atrian, S; Gonzalez-Duarte, R; Ladenstein, R.
Drosophila alcohol dehydrogenase: Acetate-enzyme interactions and novel insights into the effects of electrostatics on catalysis. Journal of Molecular Biology 2005 ;Volum 345. s. 579-598
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