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2020
1 Kashgari, Farzane Kuresh; Ravna, Aina Westrheim; Sager, Georg; Lyså, Roy Andre; Enyedy, Istvan; Dietrichs, Erik Sveberg.
Identification and experimental confirmation of novel cGMP efflux inhibitors by virtual ligand screening of vardenafil-analogues. Biomedicine and Pharmacotherapy 2020 ;Volum 126:110109. s. 1-8
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2018
2 Sager, Georg; Smaglyukova, Natalia; Fuskevåg, Ole-Martin.
The role of OAT2 (SLC22A7) in the cyclic nucleotide biokinetics of human erythrocytes. Journal of Cellular Physiology 2018 ;Volum 233.(8) s. 5972-5980
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2017
3 Ravna, Aina Westrheim; Sager, Georg.
Lørdagsuniversitetet: Drug design på data’n. Lørdagsuniversitetet; 2017-10-22 - 2017-10-22
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4 Ravna, Aina Westrheim; Sager, Georg; Fuskevåg, Ole-Martin.
Når kjemien stemmer. NRK [TV] 2017-09-26
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5 Subbotina, Anna; Ravna, Aina Westrheim; Lyså, Roy Andre; Abagyan, Ruben; Bugno, Ryszard; Sager, Georg.
Inhibition of PDE5A1 guanosine cyclic monophosphate (cGMP) hydrolysing activity by sildenafil analogues that inhibit cellular cGMP efflux. Journal of Pharmacy and Pharmacology (JPP) 2017 ;Volum 69.(6) s. 675-683
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2016
6 Chen, Xiaoyan; Lysaa, Roy; Jaeger, Ragnhild; Boadu, Emmanuel; Sager, Georg.
The effect of MRP5-expression on human erythroleukemia (HEL) cell growth and cGMP levels. Pharmacology and Pharmacy 2016 ;Volum 7. s. 64-70
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7 Dietrichs, Erik Sveberg; Sager, Georg; Tveita, Torkjel.
Altered pharmacological effects of adrenergic agonists during hypothermia. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2016 ;Volum 24:143. s. 1-9
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2015
8 Dietrichs, Erik Sveberg; Schanche, Torstein; Kondratyev, Timofey; Gaustad, Svein Erik; Sager, Georg; Tveita, Torkjel.
Negative inotropic effects of epinephrine in the presence of increased β-adrenoceptor sensitivity during hypothermia in a rat model. Cryobiology 2015 ;Volum 70.(1) s. 9-16
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2014
9 Aronsen, Lena; Ørvoll, Elin Peggy Hanne Øien; Lyså, Roy Andre; Ravna, Aina Westrheim; Sager, Georg.
Modulation of high affinity ATP-dependent cyclic nucleotide transporters by specific and non-specific cyclic nucleotide phosphodiesterase inhibitors. European Journal of Pharmacology 2014 ;Volum 745. s. 249-253
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10 Sager, Georg; Sundkvist, Elisabeth; Jæger, Ragnhild; Lyså, Roy Andre; Fuskevåg, Ole-Martin; Fuskevåg, Ole-Martin.
Sodium nitroprusside inhibits HEK293 cell growth by cGMP-dependent and independent mechanisms. Pharmacology and Pharmacy 2014 ;Volum 5.(3) s. 262-271
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2013
11 Sylte, Ingebrigt; Sager, Georg.
En pionerforsker. Ottar 2013 (297) s. 27-31
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12 Ørvoll, elin peggy hanne Øien; Lyså, Roy Andre; Ravna, aina westrheim; Sager, Georg.
Misoprostol and the sildenafil analog (PHAR- 0099048) modulate cellular efflux of cAMP and cGMP differently. Pharmacology and Pharmacy 2013 ;Volum 4.(1) s. 104-109
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2012
13 Dietrichs, Erik Sveberg; Gaustad, Svein Erik; Kondratiev, T; Sager, Georg; Tveita, Torkjel.
Hypothermia-induced dysfunction of the myocardial B1-adrenoceptor signal system. Accidental Hypothermia In The High North, The 3rd International Symposium On Accidental Hypothermia; 2012-10-22 - 2012-10-23
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14 Eggen, Tormod; Sager, Georg; Berg, Thomas; Nergaard, Birgitte; Moe, Bjørn Torvald Greve; Ørbo, Anne.
Increased Gene Expression of the ABCC5 Transporter without Distinct Changes in the Expression of PDE5 in Human Cervical Cancer Cells during Growth. Anticancer Research 2012 ;Volum 32.(8) s. 3055-3061
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15 Filseth, Ole Magnus; How, Ole-Jakob; Kondratyev, Timofey; Gamst, Tor Magne; Sager, Georg; Tveita, Torkjel.
Changes in cardiovascular effects of dopamine in response to graded hypothermia in vivo. Critical Care Medicine 2012 ;Volum 40.(1) s. 178-186
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16 Sager, Georg; Ørvoll, elin peggy hanne Øien; Lyså, Roy Andre; Kufareva, Irina; Abagyan, Ruben; Ravna, aina westrheim.
Novel cGMP Efflux Inhibitors Identified by Virtual Ligand Screening (VLS) and Confirmed by Experimental Studies. Journal of Medicinal Chemistry 2012 ;Volum 55.(7) s. 3049-3057
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2011
17 Eggen, Tormod; Sager, Georg; Arnes, Marit; Pettersen, Inger; Ørbo, Anne.
Expression of iNOS - A Favourable Prognostic Marker for Early-stage Carcinoma of the Uterine Cervix. Anticancer Research 2011 ;Volum 31.(6) s. 2319-2325
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18 Moe, Bjørn Thorvald Greve; Ørbo, Anne; Sager, Georg; Vereide, Anne Beate.
Extranuclear steroid-initiated signaling by progestin and mifepristone: concentration-dependent inhibition of Ishikawa cell proliferation and induction of apoptosis. Virchows Archiv 2011 ;Volum 459. s. S242-S242
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19 Slåtsve, Arne Martin; Ravna, aina westrheim; Lyså, Roy Andre; Sager, Georg.
ABC-transportørenes betydning for effekt og omsetning av legemidler. Tidsskrift for Den norske legeforening 2011 ;Volum 131.(11) s. 1084-1087
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2010
20 Filseth, OM; How, Ole-Jakob; Kondratiev, Timofei; Gamst, Tor Magne; Sager, Georg; Tveita, Torkjel.
DOPAMINE INFUSIONS IN NORMOTHERMIA, SEVERE HYPOTHERMIA AND DURING REWARMING: PHARMACOKINETICS AND CARDIOVASCULAR FUNCTION IN A PIG MODEL OF SURFACE COOLING AND REWARMING. Intensive Care Medicine 2010 ;Volum 36. s. S121-S121
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21 Fjelldal, Renathe; Moe, Bjørn Torvald Greve; Ørbo, Anne; Sager, Georg.
MCF-7 Cell Apoptosis and Cell Cycle Arrest: Non-genomic Effects of Progesterone and Mifepristone (RU-486). Anticancer Research 2010 ;Volum 30.(12) s. 4835-4840
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22 Sager, Georg; Livik, Marit; Hellevik, Turid; Spanne, Oddvar; Moe, Bjørn Thorvald Greve.
Radiation sensitivity of cancer cervicis cells (C4-1) and extracellular cyclic GMP as a biomarker of radiation effect.. 13th Biennial meeting of the international gynecological cancer society - IGCS 2010; 2010-10-23 - 2010-10-26
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2009
23 Moe, Bjørn Torvald Greve; Vereide, Anne Beate; Ørbo, Anne; JÆger, ragnhild; Sager, Georg.
Levonorgestrel, Medroxyprogesterone and Progesterone Cause a Concentration-dependent Reduction in Endometrial Cancer (Ishikawa) Cell Density, and High Concentrations of Progesterone and Mifepristone Act in Synergy. Anticancer Research 2009 ;Volum 29.(4) s. 1047-1052
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24 Moe, Bjørn Torvald Greve; Vereide, Anne Beate; Ørbo, Anne; Sager, Georg.
High Concentrations of Progesterone and Mifepristone Mutually Reinforce Cell Cycle Retardation and Induction of Apoptosis. Anticancer Research 2009 ;Volum 29.(4) s. 1053-1058
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25 Ravna, aina westrheim; Sager, Georg.
Molecular Modeling Studies of ABC Transporters Involved in Multidrug Resistance. Mini-Reviews in Medical Chemistry 2009 ;Volum 9.(2) s. 186-193
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26 Ravna, aina westrheim; Sager, Georg; Dahl, Svein G.; Sylte, Ingebrigt.
Membrane transporters: Structure, function and targets for drug design. I: Transporters as targets for drugs. Springer Publishing Company 2009 ISBN 978-3-540-87911-4. s. 15-51
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27 Ravna, aina westrheim; Sylte, Ingebrigt; Sager, Georg.
Binding site of ABC transporter homology models confirmed by ABCB1 crystal structure. Theoretical Biology Medical Modelling 2009 ;Volum 6.(20)
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28 Sager, Georg; Ravna, aina westrheim.
Cellular Efflux of cAMP and cGMP - A Question about Selectivity. Mini-Reviews in Medical Chemistry 2009 ;Volum 9.(8) s. 1009-1013
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2008
29 Müller, Stig; How, Ole-Jakob; Hermansen, Stig eggen; Stenberg, Thor Allan; Sager, Georg; Myrmel, truls.
Vasopressin impairs brain, heart and kidney perfusion: an experimental study in pigs after transient myocardial ischemia. Critical Care 2008 ;Volum 12.
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30 Ravna, aina westrheim; Sager, Georg.
Molecular model of the outward facing state of the human multidrug resistance protein 4 (MRP4/ABCC4). Bioorganic & Medicinal Chemistry Letters 2008 ;Volum 18.(12) s. 3481-3483
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31 Ravna, aina westrheim; Sylte, Ingebrigt; Sager, Georg.
A molecular model of a putative substrate releasing conformation of multidrug resistance protein 5 (MRP5). European Journal of Medicinal Chemistry 2008 ;Volum 43.(11) s. 2557-2567
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2007
32 Ørbo, Anne; Moe, Bjørn greve; Sager, Georg; Vereide, Anne Beate.
Extranuclear steroid-initiated signaling by progestin and mifepristone. European congress of Pathology; 2007-09-08
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33 Moe, Bjørn greve; Vereide, Anne Beate; Ørbo, Anne; Sager, Georg.
Extranuclear steroid-initiated signaling by progestin and mifepristone: Concentration dependent inhibition of Ishikawa cell proliferation and induction of apoptosis. Virchows Archiv 2007 ;Volum 451. s. 164-164
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34 Ravna, aina westrheim; Sylte, Ingebrigt; Sager, Georg.
Molecular model of the outward facing state of the human P-glycoprotein (ABCB1), and comparison to a model of the human MRP5 (ABCC5). Theoretical Biology Medical Modelling 2007 ;Volum 4. s. 33-
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35 Ørbo, Anne; Hanevik, Målfrid; JÆger, ragnhild; Van Heusden, Saskia; Sager, Georg.
Urinary cyclic GMP after treatment of gynecological cancer. A prognostic marker of clinical outcome. Anticancer Research 2007 ;Volum 27. s. 2591-2596
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36 Ørbo, Anne; Kaino, Turid; Sager, Georg; Arnes, Marit.
Bcl-2, BAX and apoptosis in endometrial hyperplasia after high dose gestagen therapy A comparison of responses in patients treated with intrauterine levonorgestrel and systemic medroxyprogesterone. European Congress of Pathology; 2007-09-08
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2006
37 Vereide, Anne Beate; Kaino, Turid; Sager, Georg; Arnes, Marit; Ørbo, Anne.
Effect of levonorgestrel IUD and oral medroxyprogesterone acetate on glandular and stromal progesterone receptors (PRA and PRB), and estrogen receptors (ER-alpha and ER-beta) in human endometrial hyperplasia. Gynecologic Oncology 2006 ;Volum 101.(3) s. 214-223
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2005
38 Sager, Georg.
Effects of progesterone on cGMP biokinetics. Farmakologisk selskaps vintermøte; 2005-01-27 - 2005-01-29
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39 Sager, Georg.
Non-genomic mechanisms beyond the antiproliferative effect of progesterone. Farmakologisk selskaps vintermøte; 2005-01-27 - 2005-01-29
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40 Sager, Georg.
Organic anion transporters, primary and tertiary transport. Farmakologisk selskaps vintermøte; 2005-01-27 - 2005-01-29
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41 Kamycheva, Elena; Jorde, Rolf; Haug, E; Sager, Georg B; Sundsfjord, Johan A.
Effects of acute hypercalcaemia on blood pressure in subjects with and without parathyroid hormone secretion. Acta Physiologica Scandinavica 2005 ;Volum 184.(2) s. 113-119
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42 Kamycheva, Elena; Jorde, Rolf; Haug, E; Sager, Georg B; Sundsfjord, Johan A.
Effects of acute hypercalcemia on blood pressure in subjects with and without parathyroid hormone secretion. Journal of Hypertension 2005 ;Volum 23. s. S94-S94
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43 Ulvestad, Line; Sager, Georg.
Syklisk GMP som biomarkør ved hjerte- og karsykdommer og kreft. Tidsskrift for Den norske legeforening 2005 ;Volum 125.(1) s. 27-28
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44 Vereide, Anne Beate; Kaino, Turid; Sager, Georg B; Ørbo, Anne.
Bcl-2, BAX, and apoptosis in endometrial hyperplasia after high dose gestagen therapy: A comparison of responses in patients treated with intrauterine levonorgestrel and systemic medroxyprogesterone. Gynecologic Oncology 2005 ;Volum 97. s. 740-750
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2004
45 Aghajani, Ebrahim; Korvald, Christian; Nordhaug, Dag Ole; Sager, Georg B; Revhaug, Arthur; Myrmel, Truls.
E. Coli sepsis induces profound mechanoenergetic inefficiency in the porcine left ventricle. Shock 2004 ;Volum 21.(2) s. 103-9
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46 Berthelsen, Eirin Listau; Endresen, Petter Cappelen; Ørbo, Anne; Sager, Georg B.
Non-genomic cell growth inhibition by progesterone. Cell cycle retardation and induction of cell death. Anticancer Research 2004 ;Volum 24.(6) s. 3749-3756
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47 Flaten, Magne Arve; Simonsen, Terje; Sager, Georg B.
Stimulant and relaxant drugs combined with stimulant and relaxant information: a study of active placebo. Psychopharmacology 2004 ;Volum 176. s. 426-434
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48 Boadu, Emmanuel; Sager, Georg B.
Reconstitution of ATP-dependent cGMP transport into proteoliposomes by membrane proteins from human erythrocytes. Scandinavian Journal of Clinical and Laboratory Investigation 2004 ;Volum 64. s. 41-48
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49 Sager, Georg B.
Cyclic GMP transporters. Neurochemistry International 2004 ;Volum 45.(6) s. 865-873
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2003
50 Sager, Georg B; Ørbo, Anne; JÆger, ragnhild; Engström, Catharina.
Non-genomic effects of progestins - Inhibition of cell growth and increased intracellular levels of cyclic nucleotides. Journal of Steroid Biochemistry and Molecular Biology 2003 ;Volum 84.(1) s. 1-8
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