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2020
1 Chaban, Viktoriia; Clarke, Gerard; Skandsen, Toril; Islam, Rakibul; Einarsen, Cathrine Elisabeth; Vik, Anne; Damås, Jan Kristian; Mollnes, Tom Eirik; Håberg, Asta; Pischke, Soeren.
Systemic inflammation persists the first year after mild traumatic brain injury: Results from the Prospective Trondheim Mild Traumatic Brain Injury Study. Journal of Neurotrauma 2020 ;Volum 37.(19) s. 2120-2130
NLSH NTNU OUS STO UiO UiT Untitled
 
2 Holter, Jan Cato; Pischke, Soeren; de Boer, Eline; Lind, Andreas; Jenum, Synne; Holten, Aleksander Rygh; Tonby, Kristian; Barratt-Due, Andreas; Sokolova, Marina; Schjalm, Camilla; Chaban, Viktoriia; Kolderup, Heidi Anette; Tran, Trung; Tollefsrud Gjølberg, Torleif; Skeie, Linda Gail; Hesstvedt, Liv; Ormaasen, Vidar; Fevang, Børre; Austad, Cathrine; Muller, Karl Erik; Fladeby, Cathrine; Holberg-Petersen, Mona; Halvorsen, Bente; Müller, Fredrik; Aukrust, Pål; Dudman, Susanne Gjeruldsen; Ueland, Thor; Andersen, Jan Terje; Lund-Johansen, Fridtjof; Heggelund, Lars; Dyrhol-Riise, Anne Ma; Mollnes, Tom Eirik.
Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients. Proceedings of the National Academy of Sciences of the United States of America 2020 ;Volum 117.(40) s. 25018-25025
NLSH NTNU OUS UiB UiO UiT VV Untitled
 
3 Jørgensen, Marthe Jøntvedt; Holter, Jan Cato; Christensen, Erik; Schjalm, Camilla; Tonby, Kristian; Pischke, Soeren; Jenum, Synne; Skeie, Linda Gail; Nur, Sarah; Lind, Andreas; Opsand, Hanne; Enersen, Tone Burvald; Grøndahl, Ragnhild; Hermann, Anne; Dudman, Susanne Gjeruldsen; Müller, Fredrik; Ueland, Thor; Mollnes, Tom Eirik; Aukrust, Pål; Heggelund, Lars; Holten, Aleksander Rygh; Dyrhol-Riise, Anne Ma.
Increased interleukin-6 and macrophage chemoattractant protein-1 are associated with respiratory failure in COVID-19. Scientific Reports 2020 ;Volum 10. s. -
NLSH NTNU OUS UiB UiO UiT VV Untitled
 
4 Laake, Jon Henrik; Aasmundstad, Tor Aksel; Kåsine, Trine; Pischke, Soeren; Barratt-Due, Andreas.
Covid-19: Evidens-, eminens-, eller erfaringsbasert behandling?. Tidsskrift for Den norske legeforening 2020 ;Volum 140.(12) s. 1-2
OUS UiO Untitled
 
5 Lipcsey, Miklos; Tenhunen, Jyrki; Pischke, Soeren; Kuitunen, Anne; Flaatten, Hans; De Geer, Lina; Sjölin, Jan; Frithiof, Robert; Chew, Michelle S.; Bendel, Stepani; Kawati, Rafael; Larsson, Anders; Mollnes, Tom Eirik; Tønnessen, Tor Inge; Rubertsson, Sten.
Endotoxin removal in septic shock with the Alteco LPS Adsorber was safe but showed no benefit compared to placebo in the double-blind randomized controlled trial - the Asset Study. Shock 2020 ;Volum 54.(2) s. 224-231
HAUKELAND NLSH NTNU OUS UiO UiT Untitled
 
6 Nieuwenhuijs-Moeke, Gertrude J.; Pischke, Soeren E.; Berger, Stefan; Sanders, Jan Stephan F; Pol, Robert A; Struys, Michel M. R. F.; Ploeg, Rutger J; Leuvenink, Henri G. D..
Ischemia and Reperfusion Injury in Kidney Transplantation: Relevant Mechanisms in Injury and Repair. Journal of Clinical Medicine 2020 ;Volum 9:253.(1) s. 1-33
OUS Untitled
 
7 Pischke, Soeren; Hødnebø, Stina; Wester, Torjus; Haugaa, Håkon; Kvernebo, Knut; Barratt-Due, Andreas; Tønnessen, Tor Inge.
Intraperitoneal microdialysis detects intestinal leakage earlier than hemodynamic surveillance and systemic inflammation in a pig model. Scandinavian Journal of Gastroenterology 2020 ;Volum 56.(2) s. 219-227
OUS UiO Untitled
 
8 Ueland, Thor; Heggelund, Lars; Lind, Andreas; Holten, Aleksander Rygh; Tonby, Kristian; Michelsen, Annika; Jenum, Synne; Jørgensen, Marthe Jøntvedt; Barratt-Due, Andreas; Skeie, Linda Gail; Nordøy, Ingvild; Fraz, Mai Sasaki Aanensen; Paulsen, Else Quist; Pischke, Soeren; Johal, Simreen Kaur; Hesstvedt, Liv; Bogen, Mette; Fevang, Børre; Halvorsen, Bente; Müller, Fredrik; Bekken, Gry Kloumann; Mollnes, Tom Eirik; Dudman, Susanne Gjeruldsen; Aukrust, Pål; Dyrhol-Riise, Anne Ma; Holter, Jan Cato.
Elevated plasma sTIM-3 levels in patients with severe COVID-19. Journal of Allergy and Clinical Immunology 2020 ;Volum 147.(1) s. 92-98
NLSH NTNU OUS UiB UiO UiT VV Untitled
 
2019
9 Ottestad, William Arne; Rognes, Ingrid Nygren; Pischke, Søren; Mollnes, Tom Eirik; Andersson, Ulf; Eken, Torsten.
Biphasic release of the alarmin high mobility group box 1 protein early after trauma predicts poor clinical outcome. Critical Care Medicine 2019 ;Volum 47.(8) s. e614-e622
NLSH NTNU OUS UiO UiT Untitled
 
10 Pischke, Søren; Hestenes, Siv Merete; Johansen, Harald Thidemann; Fure, Hilde; Bugge, Jan F; Espinoza, Andreas Westenvik; Skulstad, Helge; Edvardsen, Thor; Fosse, Erik; Mollnes, Tom Eirik; Halvorsen, Per Steinar; Nielsen, Erik Waage.
Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model. PLOS ONE 2019 ;Volum 14:e0218624.(6) s. -
NLSH NTNU OUS UiO UiT VV Untitled
 
11 Sokolova, Marina; Ekholt, Karin; Mollnes, Tom Eirik; Pischke, Søren.
HYPOXIA FOLLOWED BY WHOLE BLOOD REOXYGENATIONINDUCED ENDOTHELIAL CELL ACTIVATION IN A COMPLEMENTC5 AND TOLL-LIKE RECEPTOR CD14 DEPENDENT MANNER. 17th European Meeting on Complement in Human Disease; 2019-09-15 - 2019-09-17
UiO Untitled
 
12 Thorgersen, Ebbe Billmann; Barratt-Due, Andreas; Haugaa, Håkon; Harboe, Morten; Pischke, Søren; Nilsson, Per; Mollnes, Tom Eirik.
The role of complement in liver injury, regeneration, and transplantation.. Hepatology 2019 ;Volum 70.(2) s. 725-736
LDH NLSH NTNU OUS UiO UiT Untitled
 
2018
13 Orrem, Hilde Lang; Nilsson, Per; Pischke, Søren Erik; Grindheim, Guro; Garred, Peter; Seljeflot, Ingebjørg; Husebye, Trygve Guttorm; Aukrust, Pål; Yndestad, Arne; Andersen, Geir Øystein; Barratt-Due, Andreas; Mollnes, Tom Eirik.
Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock. ESC Heart Failure 2018 ;Volum 5.(3) s. 292-301
NLSH NTNU OUS UiO UiT Untitled
 
14 Orrem, Hilde Lang; Nilsson, Per; Pischke, Søren Erik; Kleveland, Ola; Yndestad, Arne; Ekholt, Karin; Damås, Jan Kristian; Espevik, Terje; Bendz, Bjørn; Halvorsen, Bente; Gregersen, Ida; Wiseth, Rune; Andersen, Geir Øystein; Ueland, Thor; Gullestad, Lars; Aukrust, Pål; Barratt-Due, Andreas; Mollnes, Tom Eirik.
IL-6 receptor inhibition by tocilizumab attenuated expression of C5a receptor 1 and 2 in non-ST-elevation myocardial infarction. Frontiers in Immunology 2018 ;Volum 9. s. -
NLSH NTNU OUS STO UiO UiT Untitled
 
15 Yang, Runkuan; Zhu, Shengtao; Pischke, Søren Erik; Haugaa, Håkon; Zou, Xiaoping; Tønnessen, Tor Inge.
Bile and circulating HMGB1 contributes to systemic inflammation in obstructive jaundice. Journal of Surgical Research 2018 ;Volum 228. s. 14-19
LDH OUS UiO Untitled
 
2017
16 Barratt-Due, Andreas; Pischke, Søren Erik; Nilsson, Per; Espevik, Terje; Mollnes, Tom Eirik.
Dual inhibition of complement and Toll-like receptors as a novel approach to treat inflammatory diseases-C3 or C5 emerge together with CD14 as promising targets.. Journal of Leukocyte Biology 2017 ;Volum 101.(1) s. 193-204
NLSH NTNU OUS UiO UiT Untitled
 
17 Hellerud, Bernt C; Orrem, Hilde Lang; Dybwik, Knut Gustav; Pischke, Søren Erik; Barratt-Due, Andreas; Castellheim, Albert; Fure, Hilde; Bergseth, Grete; Christiansen, Dorte; Nunn, Miles A.; Espevik, Terje; Lau, Corinna; Brandtzæg, Petter; Nielsen, Erik Waage; Mollnes, Tom Eirik.
Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis. Journal of Intensive Care 2017 ;Volum 5:21. s. 1-9
NORD NLSH NTNU OUS UiO UiT Untitled
 
18 Pischke, Søren Erik; Gustavsen, Alice; Orrem, Hilde Lang; Egge, Kjetil Hagene; Courivaud, Fredric A A; Fontenelle, Hugues; Despont, Alain; Bongoni, Anjan K.; Rieben, Robert; Tønnessen, Tor Inge; Nunn, Miles A.; Scott, Helge; Skulstad, Helge; Barratt-Due, Andreas; Mollnes, Tom Eirik.
Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function. Basic Research in Cardiology 2017 ;Volum 112:20.(3) s. -
NLSH NTNU OUS UiO UiT Untitled
 
19 Pischke, Søren Erik; Haugaa, Håkon; Haney, Michael.
A neglected organ in multiple organ failure - 'skin in the game'?. Acta Anaesthesiologica Scandinavica 2017 ;Volum 61.(1) s. 5-7
OUS UiO Untitled
 
2016
20 Gustavsen, Alice; Nymo, Stig Haugset; Landsem, Anne; Christiansen, Dorte; Ryan, Liv; Husebye, Harald; Lau, Corinna; Pischke, Søren Erik; Lambris, John D.; Espevik, Terje; Mollnes, Tom Eirik.
Combined inhibition of complement and CD14 attenuates bacteria-induced inflammation in human whole blood more efficiently than antagonizing the toll-like receptor 4-MD2 complex. Journal of Infectious Diseases 2016 ;Volum 214.(1) s. 140-150
NLSH NTNU OUS UiO UiT Untitled
 
2015
21 Egge, Kjetil Hagene; Thorgersen, Ebbe Billmann; Pischke, Søren Erik; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Bongoni, Anjan K.; Rieben, Robert; Nunn, Miles A.; Barratt-Due, Andreas; Mollnes, Tom Eirik.
Organ inflammation in porcine Escherichia coli sepsis is markedly attenuated by combined inhibition of C5 and CD14. Immunobiology 2015 ;Volum 220.(8) s. 999-1005
NLSH NTNU OUS UiO UiT Untitled
 
22 Fretland, Åsmund Avdem; Sokolov, Andrey; Postriganova, Nadezda; Kazaryan, Airazat M.; Pischke, Søren Erik; Nilsson, Per; Rognes, Ingrid Nygren; Bjørnbeth, Bjørn Atle; Fagerland, Morten; Mollnes, Tom Eirik; Edwin, Bjørn.
Inflammatory response after laparoscopic versus open resection of colorectal liver metastases: Data from the oslo-comet trial. Medicine 2015 ;Volum 94:e1786.(42) s. -
HFI NLSH NTNU OUS UiT Untitled
 
23 Hyler, Stefan; Pischke, Søren Erik; Halvorsen, Per Steinar; Espinoza, Andreas Westenvik; Bergsland, Jacob; Tønnessen, Tor Inge; Fosse, Erik; Skulstad, Helge.
Continuous monitoring of regional function by a miniaturized ultrasound transducer allows early quantification of low-grade myocardial ischemia. Journal of the American Society of Echocardiography 2015 ;Volum 28.(4) s. 486-494
OUS UiO Untitled
 
24 Khan, Faraz Hameed; Pharo, Anne Margrethe; Lindstad, Julie Katrine; Mollnes, Tom Eirik; Tønnessen, Tor Inge; Pischke, Søren Erik.
Effect of Perfusion Fluids on Recovery of Inflammatory Mediators in Microdialysis. Scandinavian Journal of Immunology 2015 ;Volum 82.(5) s. 467-475
NLSH NTNU OUS UiO UiT Untitled
 
25 Pischke, Søren Erik; Hyler, Stefan; Tronstad, Christian; Bergsland, Jacob; Fosse, Erik; Halvorsen, Per Steinar; Skulstad, Helge; Tønnessen, Tor Inge.
Myocardial tissue CO2 tension detects coronary blood flow reduction after coronary artery bypass in real-time. British Journal of Anaesthesia 2015 ;Volum 114.(3) s. 414-422
OUS UiO Untitled
 
2014
26 Huber-Lang, Markus; Barratt-Due, Andreas; Pischke, Søren Erik; Sandanger, Øystein; Nilsson, Per; Nunn, Miles A.; Denk, Stephanie; Gaus, Wilhelm; Espevik, Terje; Mollnes, Tom Eirik.
Double blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice. Journal of Immunology 2014 ;Volum 192.(11) s. 5324-5331
NLSH NTNU OUS UiO UiT Untitled
 
2013
27 Barratt-Due, Andreas; Sokolov, Andrey; Gustavsen, Alice; Hellerud, Bernt C; Egge, Kjetil Hagene; Pischke, Søren Erik; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Castellheim, Albert; Thorgersen, Ebbe Billmann; Mollnes, Tom Eirik.
Polyvalent immunoglobulin significantly attenuated the formation of IL-1 beta in Escherichia coli-induced sepsis in pigs. Immunobiology 2013 ;Volum 218.(5) s. 683-689
DIAKON OUS UiO Untitled
 
28 Barratt-Due, Andreas; Thorgersen, Ebbe Billmann; Egge, Kjetil Hagene; Pischke, Søren Erik; Sokolov, Andrey; Hellerud, Bernt C; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Bongoni, Anjan K.; Rieben, Robert; Nunn, Miles; Scott, Helge; Mollnes, Tom Eirik.
Combined Inhibition of Complement (C5) and CD14 Markedly Attenuates Inflammation, Thrombogenicity, and Hemodynamic Changes in Porcine Sepsis. Journal of Immunology 2013 ;Volum 191.(2) s. 819-827
OUS UiO Untitled
 
29 Haugaa, Håkon; Almaas, Runar; Thorgersen, Ebbe Billmann; Foss, Aksel; Line, Pål Dag; Sanengen, Truls; Bergmann, Gisli Bjørn; Olin, Per Bertil Mårten; Wælgaard, Lars Torbjørn; Grindheim, Guro; Pischke, Søren Erik; Mollnes, Tom Eirik; Tønnessen, Tor Inge.
Clinical experience with microdialysis catheters in pediatric liver transplants. Liver transplantation 2013 ;Volum 19.(3) s. 305-314
OUS UiO Untitled
 
30 Mollnes, Tom Eirik; Barratt-Due, Andreas; Pischke, Søren Erik; Sandanger, Inger; Nilsson, Per; Lambris, J; Nunn, Miles A.; Denk, Stephanie; Espevik, Terje; Huber-Lang, Markus.
Double-blockade of CD14 and complement component C5 abolish the inflammatory storm and improve survival in mouse polymicrobial sepsis. Molecular Immunology 2013 ;Volum 56.(3) s. 294-294
NTNU OUS UiO Untitled
 
31 Thorgersen, Ebbe Billmann; Pischke, Søren Erik; Barratt-Due, Andreas; Fure, Hilde; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Hellerud, Bernt C; Mollnes, Tom Eirik.
Systemic CD14 inhibition attenuates organ inflammation in porcine escherichia coli sepsis. Infection and Immunity 2013 ;Volum 81.(9) s. 3173-3181
NLSH OUS UiO VV Untitled
 
2012
32 Barratt-Due, Andreas; Pischke, Søren Erik; Brekke, Ole Lars; Thorgersen, Ebbe Billmann; Nielsen, Erik Waage; Espevik, Terje; Huber-Lang, Markus; Mollnes, Tom Eirik.
Bride and groom in systemic inflammation - The bells ring for complement and Toll in cooperation. Immunobiology 2012 ;Volum 217.(11) s. 1047-1056
NORD NLSH NTNU OUS UiO UiT Untitled
 
33 Barratt-Duel, Andreas; Thorgersen, Ebbe Billmann; Egge, Kjetil Hagene; Pischke, Søren Erik; Sokolov, Andrey; Hellerud, Bernt C; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Nunn, Miles A.; Scott, Helge; Mollnes, Tom Eirik.
Combined inhibition of complement (C5) and CD14 markedly attenuates blood thrombogenicity, inflammation and hemodynamic changes in porcine sepsis. Immunobiology 2012 ;Volum 217.(11) s. 1152-1152
OUS UiO Untitled
 
34 Haugaa, Håkon; Thorgersen, Ebbe Billmann; Pharo, Anne Margrethe; Boberg, Kirsten Muri; Foss, Aksel; Line, Pål Dag; Sanengen, Truls; Almaas, Runar; Grindheim, Guro; Wælgaard, Lars Torbjørn; Pischke, Søren Erik; Mollnes, Tom Eirik; Tønnessen, Tor Inge.
Inflammatory markers sampled by microdialysis catheters distinguish rejection from ischemia in liver grafts. Liver transplantation 2012 ;Volum 18.(12) s. 1421-1429
OUS UiO Untitled
 
35 Haugaa, Håkon; Thorgersen, Ebbe Billmann; Pharo, Anne Margrethe; Boberg, Kirsten Muri; Foss, Aksel; Line, Pål Dag; Sanengen, Truls; Almaas, Runar; Grindheim, Guro; Pischke, Søren Erik; Mollnes, Tom Eirik; Tønnessen, Tor Inge.
Early bedside detection of ischemia and rejection in liver transplants by microdialysis. Liver transplantation 2012 ;Volum 18.(7) s. 839-849
OUS UiO Untitled
 
36 Mollnes, Tom Eirik; Barratt-Due, Andreas; Pischke, Søren Erik; Sandanger, Øystein; Nunn, Miles A.; Espevik, Terje; Denk, Stephanie; Huber-Lang, Markus.
The systemic inflammatory reaction in polymicrobial sepsis induced by murine cecal ligation and puncture is equally dependent on C5 and CD14. Immunobiology 2012 ;Volum 217.(11) s. 1129-1129
NTNU OUS UiO Untitled
 
37 Pischke, Søren Erik; Tronstad, Christian; Holhjem, Lars; Halvorsen, Per Steinar; Tønnessen, Tor Inge.
Perioperative detection of myocardial ischaemia/reperfusion with a novel tissue CO2 monitoring technology. European Journal of Cardio-Thoracic Surgery 2012 ;Volum 42.(1) s. 157-163
OUS UiO Untitled
 
38 Pischke, Søren Erik; Tronstad, Christian; Holhjem, Lars; Line, Pål Dag; Haugaa, Håkon; Tønnessen, Tor Inge.
Hepatic and Abdominal Carbon Dioxide Measurements Detect and Distinguish Hepatic Artery Occlusion and Portal Vein Occlusion in Pigs. Liver transplantation 2012 ;Volum 18.(12) s. 1485-1494
OUS UiO Untitled
 
39 Thorgersen, Ebbe Billmann; Pischke, Søren Erik; Barratt-Due, Andreas; Fure, Hilde; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Hellerud, Bernt C; Mollnes, Tom Eirik.
Systemic CD14-inhibition attenuates local inflammatory responses organ-dependently in porcine Escherichia coli-sepsis. Immunobiology 2012 ;Volum 217.(11) s. 1206-1206
NLSH OUS UiO VV Untitled
 
2010
40 Hyler, Stefan; Pischke, Søren Erik; Halvorsen, Per Steinar; Espinoza, Andreas Westenvik; Hestenes, Siv Merete; Bergsland, Jacob; Fosse, Erik; Skulstad, Helge.
Systolic and postsystolic velocities quantify low grade myocardial ischaemia by a miniaturized epicardial ultrasonic sensor. European Heart Journal 2010 ;Volum 31. s. 45-45
OUS Untitled
 
41 Tronstad, Christian; Pischke, Søren Erik; Holhjem, L; Tønnessen, Tor Inge; Martinsen, Ørjan Grøttem; Grimnes, Sverre.
Early detection of cardiac ischemia using a conductometric pCO(2) sensor: real-time drift correction and parameterization. Physiological Measurement 2010 ;Volum 31.(9) s. 1241-1255
OUS UiO Untitled