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2019
1 Gjestad, Caroline; Hole, Kristine; Haslemo, Tore; Diczfalusy, Ulf; Molden, Espen.
Effect of Grapefruit Juice Intake on Serum Level of the Endogenous CYP3A4 Metabolite 4β-Hydroxycholesterol—an Interaction Study in Healthy Volunteers. AAPS Journal 2019 ;Volum 21.(58) s. -
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2 Jukic, Marin M.; Smith, Robert Løvsletten; Haslemo, Tore; Molden, Espen; Ingelman-Sundberg, Magnus.
Effect of CYP2D6 genotype on exposure and efficacy of risperidone and aripiprazole: a retrospective, cohort study. Lancet psychiatry 2019 ;Volum 6.(5) s. 418-426
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3 Lea, Marianne; Mowe, Morten; Mathiesen, Liv; Kvernrød, Kristin; Skovlund, Eva; Molden, Espen.
Prevalence and risk factors of drug-related hospitalizations in multimorbid patients admitted to an internal medicine ward. PLOS ONE 2019 ;Volum 14.(7) s. -
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4 Olsen, Thomasch R. Risom; Rasmussen, Anders R.; Kringen, Marianne K.; Molden, Espen.
En jente i tidlig skolealder uten effekt av opioider ved generell anestesi. Tidsskrift for Den norske legeforening 2019 ;Volum 139.(7) s. -
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5 Romskaug, Rita; Skovlund, Eva; Straand, Jørund; Molden, Espen; Kersten, Hege; Pitkala, Kaisu H; Lundqvist, Christofer; Wyller, Torgeir Bruun.
Effect of clinical geriatric assessments and collaborative medication reviews by geriatrician and family physician for improving health-related quality of life in home-dwelling older patients receiving polypharmacy: a cluster randomized clinical trial. JAMA Internal Medicine 2019 s. -
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6 Smith, Robert Løvsletten; Kyllesø, Lennart; Haslemo, Tore; Andreassen, Ole Andreas; Molden, Espen.
Reduction in N-desmethylclozapine level is determined by daily dose but not serum concentration of valproic acid-indications of a presystemic interaction mechanism. Therapeutic Drug Monitoring 2019 ;Volum 41.(4) s. 503-508
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7 Tveito, Marit; Smith, Robert Løvsletten; Høiseth, Gudrun; Molden, Espen.
The Effect of Valproic Acid on Olanzapine Serum Concentration: A Study Including 2791 Patients Treated With Olanzapine Tablets or Long-Acting Injections. Journal of Clinical Psychopharmacology 2019 ;Volum 39.(6) s. 561-566
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8 Vedal, Trude Seselie Jahr; Steen, Nils Eiel; Birkeland, Kåre I.; Dieset, Ingrid; Reponen, Elina Johanna; Anderssen, Jannicke Fjæra; Rødevand, Linn; Melle, Ingrid; Andreassen, Ole Andreas; Molden, Espen; Jönsson, Erik Gunnar.
Adipokine levels are associated with insulin resistance in antipsychotics users independently of BMI. Psychoneuroendocrinology 2019 ;Volum 103. s. 87-95
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9 Wollmann, Birgit Malene Tovik; Lunde, Hilde; Støten, Lene; Lunder, Niclas; Molden, Espen.
Substantial Differences in Serum Concentrations of Psychoactive Drugs Measured in Samples Stored for 2 Days or More on Standard Serum Tubes Versus Serum Tubes Containing Gel Separators. Therapeutic Drug Monitoring 2019 ;Volum 41.(3) s. 396-400
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2018
10 Baftiu, Arton; Feet, Silje Andrea; Larsson, Pål Gunnar; Burns, Margrete Larsen; Henning, Oliver Johannes; Sætre, Erik; Molden, Espen; Granås, Anne Gerd; Johannessen, Svein Ivar; Landmark, Cecilie Johannessen.
Utilisation and polypharmacy aspects of antiepileptic drugs in elderly versus younger patients with epilepsy: A pharmacoepidemiological study of CNS-active drugs in Norway, 2004-2015. Epilepsy Research 2018 ;Volum 139. s. 35-42
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11 Dyrkorn, Roar; Lundgaard, Halvor; Stokes, Charlotte Lorentze; Molden, Espen; Spigset, Olav.
Serumkonsentrasjonsmålinger av DOAK-legemidler. Tidsskrift for Den norske legeforening 2018 ;Volum 138.(7) s. 620-621
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12 Gjestad, Caroline; Haslemo, Tore; Andreassen, Ole Andreas; Molden, Espen.
Gjestad et al. reply to 'Was 4β-hydroxycholesterol ever going to be a useful marker of CYP3A4 activity?' by Neuhoff and Tucker. British Journal of Clinical Pharmacology 2018 ;Volum 84.(7) s. 1624-1625
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13 Haslemo, Tore; Eliasson, Erik; Jukic, Marin M.; Ingelman-Sundberg, Magnus; Molden, Espen.
Significantly lower CYP2D6 metabolism measured as the O/N-desmethylvenlafaxine metabolic ratio in carriers of CYP2D6*41 versus CYP2D6*9 or CYP2D6*10: a study on therapeutic drug monitoring data from 1003 genotyped Scandinavian patients. British Journal of Clinical Pharmacology 2018 s. -
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14 Hole, Kristine; Heiberg, Petra Lybæk; Gjestad, Caroline; Mehus, Lise Larsen; Rø, Øyvind; Molden, Espen.
Elevated 4β‐hydroxycholesterol/cholesterol ratio in anorexianervosa patients. Pharmacology Research & Perspectives 2018 ;Volum 6.(5) s. 1-5
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15 Hole, Kristine; Wollmann, Birgit Malene Tovik; Nguyen, Camilla; Haslemo, Tore; Molden, Espen.
Comparison of CYP3A4-Inducing Capacity of Enzyme-Inducing Antiepileptic Drugs Using 4β-Hydroxycholesterol as Biomarker. Therapeutic Drug Monitoring 2018 ;Volum 40.(4) s. 463-468
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16 Ihle-Hansen, Håkon; Hagberg, Guri; Molden, Espen; Myrstad, Marius.
Hvem bør få klopidogrel etter hjerneslag?. Tidsskrift for Den norske legeforening 2018 ;Volum 138.(9) s. -
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17 Iversen, Trude Seselie Jahr; Steen, Nils Eiel; Dieset, Ingrid; Hope, Sigrun; Mørch, Ragni Helene; Gardsjord, Erlend Strand; Jørgensen, Kjetil Nordbø; Melle, Ingrid; Andreassen, Ole Andreas; Molden, Espen; Jönsson, Erik Gunnar.
Side effect burden of antipsychotic drugs in real life - Impact of gender and polypharmacy. Progress in Neuro-psychopharmacology and Biological Psychiatry 2018 ;Volum 82. s. 263-271
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18 Jukic, Marin M.; Haslemo, Tore; Molden, Espen; Ingelman-Sundberg, Magnus.
Impact of CYP2C19 Genotype on Escitalopram Exposure and Therapeutic Failure: A Retrospective Study Based on 2,087 Patients. American Journal of Psychiatry 2018 ;Volum 175.(5) s. 463-470
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19 Pardiñas, Antonio F.; Holmans, Peter; Pocklington, Andrew J.; Escott-Price, Valentina; Ripke, Stephan; Carrera, Noa; Legge, Sophie E.; Bishop, Sophie; Cameron, Darren; Hamshere, Marian L.; Han, Jun; Hubbard, Leon; Lynham, Amy; Mantripragada, Kiran; Rees, Elliott; MacCabe, James H.; McCarroll, Steven A.; Baune, Bernhard T.; Breen, Gerome; Byrne, Enda M.; Dannlowski, Udo; Eley, Thalia C.; Hayward, Caroline; Martin, Nicholas G.; McIntosh, Andrew M.; Plomin, Robert; Porteous, David J.; Wray, Naomi R.; Caballero, Armando; Geschwind, Daniel H.; Huckins, Laura M.; Ruderfer, Douglas M.; Santiago, Enrique; Sklar, Pamela; Stahl, Eli A.; Won, Hyejung; Agerbo, Esben; Als, Thomas D.; Andreassen, Ole Andreas; Bækvad-Hansen, Marie; Mortensen, Preben Bo; Pedersen, Carsten Bøcker; Børglum, Anders D.; Bybjerg-Grauholm, Jonas; Djurovic, Srdjan; Durmishi, Naser; Pedersen, Marianne Giørtz; Golimbet, Vera; Grove, Jakob; Hougaard, David M.; Mattheisen, Manuel; Molden, Espen; Mors, Ole; Nordentoft, Merete; Pejovic-Milovancevic, Milica; Sigurdsson, Engilbert; Silagadze, Teimuraz; Hansen, Christine Søholm; Stefansson, Kari; Stefansson, Hreinn; Steinberg, Stacy; Tosato, Sarah; Werge, Thomas; Collier, David A; Owen, Michael J; O'Donovan, Michael C; Walters, James T R; Collier, David A.; Rujescu, Dan; Kirov, George; Owen, Michael J.; O'Donovan, Michael C.; Walters, James T.R..
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. Nature Genetics 2018 ;Volum 50.(3) s. 381-389
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20 Smith, Robert Løvsletten; Haslemo, Tore; Chan, Hilde Fauskrud; Refsum, Helge; Molden, Espen.
Clinically Relevant Effect of UGT1A4*3 on Lamotrigine Serum Concentration Is Restricted to Postmenopausal Women—A Study Matching Therapeutic Drug Monitoring and Genotype Data From 534 Patients. Therapeutic Drug Monitoring 2018 ;Volum 40.(5) s. 567-571
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21 Tveito, Marit; Smith, Robert Løvsletten; Molden, Espen; Haslemo, Tore; Refsum, Helge; Hartberg, Cecilie Bhandari; Correll, Christoph U.; Høiseth, Gudrun.
Age Impacts Olanzapine Exposure Differently During Use of Oral Versus Long-Acting Injectable Formulations: An Observational Study Including 8,288 Patients. Journal of Clinical Psychopharmacology 2018 ;Volum 38.(6) s. 570-576
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22 Vedal, Trude Seselie Jahr; Steen, Nils Eiel; Birkeland, Kåre I.; Dieset, Ingrid; Reponen, Elina Johanna; Anderssen, Jannicke Fjæra; Rødevand, Linn; Melle, Ingrid; Andreassen, Ole Andreas; Molden, Espen; Jönsson, Erik Gunnar.
Free thyroxine and thyroid-stimulating hormone in severe mental disorders: A naturalistic study with focus on antipsychotic medication. Journal of Psychiatric Research 2018 ;Volum 106. s. 74-81
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23 Vedal, Trude Seselie Jahr; Steen, Nils Eiel; Birkeland, Kåre I.; Dieset, Ingrid; Reponen, Elina Johanna; Laskemoen, Jannicke F.; Rødevand, Linn; Melle, Ingrid; Andreassen, Ole Andreas; Molden, Espen; Jönsson, Erik Gunnar.
Response: Are thyroid abnormalities only related to antipsychotic treatment in patients with severe mental disorders?. Journal of Psychiatric Research 2018 s. -
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24 Viktil, Kirsten Kilvik; Lehre, Ina; Ranhoff, Anette Hylen; Molden, Espen.
Serum concentrations and elimination rates of direct-acting oral anticoagulants (DOACs) in older hip fracture patients hospitalized for surgery: a pilot study. Drugs & Aging 2018 ;Volum 36.(1) s. 65-71
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25 Wollmann, Birgit Malene Tovik; Syversen, Silje Watterdal; Vistnes, Maria; Lie, Elisabeth; Mehus, Lise Larsen; Molden, Espen.
Associations between cytokine levels and CYP3A4 phenotype in patients with rheumatoid arthritis. Drug Metabolism And Disposition 2018 ;Volum 46.(10) s. 1384-1389
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2017
26 Wollmann, Birgit Malene Tovik; Syversen, Silje Watterdal; Lie, Elisabeth; Gjestad, Caroline; Mehus, Lise Larsen; Olsen, Inge Christoffer; Molden, Espen.
4β-hydroxycholesterol level in patients with rheumatoid arthritis before vs. after initiation of bDMARDs and correlation with inflammatory state. Clinical and Translational Science 2017 ;Volum 10.(1) s. 42-49
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27 Gjestad, Caroline; Haslemo, Tore; Andreassen, Ole Andreas; Molden, Espen.
4β-Hydroxycholesterol level significantly correlates with steady-state serum concentration of the CYP3A4 substrate quetiapine in psychiatric patients. British Journal of Clinical Pharmacology 2017 ;Volum 83.(11) s. 2398-2405
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28 Hole, Kristine; Gjestad, Caroline; Heitmann, Kristine; Haslemo, Tore; Molden, Espen; Bremer, Sara.
Impact of genetic and nongenetic factors on interindividual variability in 4β-hydroxycholesterol concentration. European Journal of Clinical Pharmacology 2017 ;Volum 73.(3) s. 317-324
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29 Hole, Kristine; Størset, Elisabet; Olastuen, Ane; Haslemo, Tore; Kro, Grete Birkeland; Midtvedt, Karsten; Åsberg, Anders; Molden, Espen.
Recovery of CYP3A Phenotype after Kidney Transplantation. Drug Metabolism And Disposition 2017 ;Volum 45.(12) s. 1260-1265
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30 Kringen, Marianne K.; Chalabianloo, Fatemeh; Bernard, Jean-Paul Anthony; Bramness, Jørgen Gustav; Molden, Espen; Høiseth, Gudrun.
Combined Effect of CYP2B6 Genotype and Other Candidate Genes on a Steady-State Serum Concentration of Methadone in Opioid Maintenance Treatment. Therapeutic Drug Monitoring 2017 ;Volum 39.(5) s. 550-555
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31 Lea, Marianne; Mathiesen, Liv; Mowe, Morten; Molden, Espen.
Baseline characteristics of multimorbid patients included in an RCT. 46th ESCP Symposium on Clinical Pharmacy; 2017-10-09 - 2017-10-11
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32 Romskaug, Rita; Molden, Espen; Straand, Jørund; Kersten, Hege; Skovlund, Eva; Pitkala, Kaisu H; Wyller, Torgeir Bruun.
Cooperation between geriatricians and general practitioners for improved pharmacotherapy in home-dwelling elderly people receiving polypharmacy - the COOP Study: Study protocol for a cluster randomised controlled trial. Trials 2017 ;Volum 18.(1)
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33 Smith, Robert Løvsletten; Haslemo, Tore; Andreassen, Ole Andreas; Eliasson, Erik; Dahl, Marja-Liisa; Spigset, Olav; Molden, Espen.
Correlation between serum concentrations of N-desmethylclozapine and granulocyte levels in patients with schizophrenia: a retrospective observational study. CNS Drugs 2017 ;Volum 31.(11) s. 991-997
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34 Solberg, Dag; Refsum, Helge; Molden, Espen.
Hvis du skal gjøre det, gjør det riktig!. Tidsskrift for Den norske legeforening 2017 ;Volum 137.(12/13) s. 854-854
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35 Solhaug, Vigdis; Molden, Espen.
Individual variability in clinical effect and tolerability of opioid analgesics ? Importance of drug interactions and pharmacogenetics. Scandinavian Journal of Pain 2017 ;Volum 17. s. 193-200
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36 Størset, Elisabet; Hole, Kristine; Midtvedt, Karsten; Bergan, Stein; Molden, Espen; Åsberg, Anders.
Bodyweight-adjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance. British Journal of Clinical Pharmacology 2017 ;Volum 83.(6) s. 1350-1352
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37 Størset, Elisabet; Hole, Kristine; Midtvedt, Karsten; Bergan, Stein; Molden, Espen; Åsberg, Anders.
Response to: ‘Response to: Bodyweightadjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance’. British Journal of Clinical Pharmacology 2017 ;Volum 83.(6) s. 1357-1358
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38 Størset, Elisabet; Hole, Kristine; Midtvedt, Karsten; Bergan, Stein; Molden, Espen; Åsberg, Anders.
The CYP3A biomarker 4β-hydroxycholesterol does not improve tacrolimus dose predictions early after kidney transplantation. British Journal of Clinical Pharmacology 2017 ;Volum 83.(7) s. 1457-1465
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39 Svendsen, Torleiv; Brodtkorb, Eylert; Reimers, Arne; Molden, Espen; Sætre, Erik; Johannessen, Svein Ivar; Landmark, Cecilie Johannessen.
Pharmacokinetic variability, efficacy and tolerability of eslicarbazepine acetate – A national approach to the evaluation of therapeutic drug monitoring data and clinical outcome. Epilepsy Research 2017 ;Volum 129. s. 125-131
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40 Waade, Ragnhild Birkeland; Molden, Espen; Martinsen, Mette; Hermann, Monica; Ranhoff, Anette Hylen.
Psychotropics and weak opioid analgesics in plasma samples of older hip fracture patients - detection frequencies and consistency with drug records. British Journal of Clinical Pharmacology 2017 ;Volum 83.(7) s. 1397-1404
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41 Westin, Andreas; Brekke, Malin; Molden, Espen; Skogvoll, Eirik; Aadal, Marianne; Spigset, Olav.
Changes in drug disposition of lithium during pregnancy: A retrospective observational study of patient data from two routine therapeutic drug monitoring services in Norway. BMJ Open 2017 ;Volum 7.(3)
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42 Westin, Andreas; Brekke, Malin; Molden, Espen; Skogvoll, Eirik; Castberg, Ingrid Mehli; Spigset, Olav.
Treatment with antipsychotics in pregnancy: changes in drug disposition. Clinical Pharmacology and Therapeutics 2017 ;Volum 103.(3) s. 477-484
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43 Westin, Andreas; Brekke, Malin; Molden, Espen; Skogvoll, Eirik; Spigset, Olav.
Selective serotonin reuptake inhibitors and venlafaxine in pregnancy: Changes in drug disposition. PLOS ONE 2017 ;Volum 12.(7) s. -
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2016
44 Gjestad, Caroline; Huynh, Duy Khanh; Haslemo, Tore; Molden, Espen.
4β-Hydroxycholesterol correlates with dose but not steady-state concentration of carbamazepine: indication of intestinal CYP3A in biomarker formation?. British Journal of Clinical Pharmacology 2016 ;Volum 81.(2) s. 269-276
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45 Lea, Marianne; Barstad, Ingeborg; Mathiesen, Liv; Mowe, Morten; Molden, Espen.
Effect of teaching and checklist implementation on accuracy of medication history recording at hospital admission. International Journal of Clinical Pharmacy 2016 ;Volum 38.(1) s. 20-24
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46 Lea, Marianne; Engnes, Anette; Mathiesen, Liv; Mowe, Morten; Molden, Espen.
Drug-related problems at hospital admission in multimorbid internal medical patients. 45th ESCP Symposium on Clinical Pharmacy; 2016-10-05 - 2016-10-07
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47 Lundgaard, Halvor; Dyrkorn, Roar; Stokes, Charlotte Lorentze; Molden, Espen; Spigset, Olav.
Tryggere behandling med serumkonsentrasjonsmåling av de nye antikoagulasjonsmidlene?. Tidsskrift for Den norske legeforening 2016 ;Volum 136.(18) s. 1556-1560
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48 Mannheimer, Buster; Haslemo, Tore; Lindh, Jonatan D.; Eliasson, Erik; Molden, Espen.
Risperidone and Venlafaxine Metabolic Ratios Strongly Predict a CYP2D6 Poor Metabolizing Genotype. Therapeutic Drug Monitoring 2016 ;Volum 38.(1) s. 127-134
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49 Molden, Espen; Waade, Ragnhild Birkeland; Hoff, Maren; Haslemo, Tore.
Impact of Ageing on Serum Concentrations of Risperidone and Its Active Metabolite in Patients with Known CYP2D6 Genotype. Basic & Clinical Pharmacology & Toxicology 2016 ;Volum 119.(5) s. 470-475
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50 Smith, Robert Løvsletten; Haslemo, Tore; Refsum, Helge; Molden, Espen.
Impact of age, gender and CYP2C9/2C19 genotypes on dose-adjusted steady-state serum concentrations of valproic acid—a large-scale study based on naturalistic therapeutic drug monitoring data. European Journal of Clinical Pharmacology 2016 ;Volum 72.(9) s. 1099-1104
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