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2020
1 Aas, Vigdis; Thoresen, G. Hege; Rustan, Arild; Lund, Jenny.
Substrate oxidation in primary human skeletal muscle cells is influenced by donor age. Cell and Tissue Research 2020 ;Volum 382. s. 599-608
OSLOMET UiO Untitled
 
2 Lund, Jenny; Rustan, Arild.
Fatty Acids: Structures and Properties. Encyclopedia of Life Sciences 2020
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3 Løvsletten, Nils Gunnar; Vu, Helene Loang Ngo; Skagen, Christine; Lund, Jenny; Kase, Eili Tranheim; Thoresen, G. Hege; Zammit, Victor A.; Rustan, Arild.
Treatment of human skeletal muscle cells with inhibitors of diacylglycerol acyltransferases 1 and 2 to explore isozyme-specific roles on lipid metabolism. Scientific Reports 2020 ;Volum 10:238. s. 1-13
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4 Mars, Tomaz; Mis, Katarina; Meznaric, Marija; Mihevc, Sonja Prpar; Vid, Jan; Haugen, Fred; Rogelj, Boris; Rustan, Arild; Thoresen, G. Hege; Pirkmajer, Sergej; Nikolic, Natasa.
Innervation and electrical pulse stimulation – in vitro effects on human skeletal muscle cells. Applied Physiology, Nutrition and Metabolism 2020 s. -
STAMI UiO Untitled
 
2019
5 Lindquist, Carine; Bjørndal, Bodil; Bakke, Hege Gilbø; Slettom, Grete; Clason, Marie Karoliussen; Rustan, Arild; Thoresen, G. Hege; Skorve, Jon; Nygård, Ottar; Berge, Rolf Kristian.
A mitochondria-targeted fatty acid analogue influences hepatic glucose metabolism and reduces the plasma insulin/glucose ratio in male Wistar rats. PLOS ONE 2019 ;Volum 14:e0222558.(9) s. 1-17
HAUKELAND UiB UiO Untitled
 
6 Løvsletten, Nils Gunnar; Rustan, Arild; Laurens, Claire; Thoresen, G. Hege; Moro, Cedric; Nikolic, Natasa.
Primary defects in lipid handling and resistance to exercise in myotubes from obese donors with and without type 2 diabetes. Applied Physiology, Nutrition and Metabolism 2019
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7 Pettersen, Ina Katrine Nitschke; Tusubira, Deusdedit; Ashrafi, Hanan; Dyrstad, Sissel Elisabeth; Hansen, Lena; Liu, Xiaozheng; Hodneland, Linn I.; Løvsletten, Nils Gunnar; Berge, Kjetil; Wergedahl, Hege; Bjørndal, Bodil; Fluge, Øystein; Bruland, Ove; Rustan, Arild; Halberg, Nils; Røsland, Gro Vatne; Berge, Rolf Kristian; Tronstad, Karl Johan.
Upregulated PDK4 expression is a sensitive marker of increased fatty acid oxidation. Mitochondrion (Amsterdam. Print) 2019 ;Volum 49. s. 97-110
HAUKELAND HVL UiB UiO Untitled
 
2018
8 Lund, Jenny; Helle, Siw A; Li, Yuchuan; Løvsletten, Nils Gunnar; Stadheim, Hans Kristian; Jensen, Jørgen; Kase, Eili Tranheim; Thoresen, G. Hege; Rustan, Arild.
Higher lipid turnover and oxidation in cultured human myotubes from athletic versus sedentary young male subjects. Scientific Reports 2018 ;Volum 8.(1) s. -
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9 Løvsletten, Nils Gunnar; Bakke, Siril Skaret; Kase, Eili Tranheim; Ouwens, D. Margriet; Thoresen, G. Hege; Rustan, Arild.
Increased triacylglycerol - Fatty acid substrate cycling in human skeletal muscle cells exposed to eicosapentaenoic acid. PLOS ONE 2018 ;Volum 13:e0208048.(11) s. 1-15
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2017
10 Feng, Yuan Zeng; Lund, Jenny; Li, Yuchuan; Knabenes, Irlin; Bakke, Siril Skaret; Kase, Eili Tranheim; Lee, Yun K; Kimmel, Alan R; Thoresen, G. Hege; Rustan, Arild; Dalen, Knut Tomas.
Loss of perilipin 2 in cultured myotubes enhances lipolysis and redirects the metabolic energy balance from glucose oxidation towards fatty acid oxidation. Journal of Lipid Research 2017 ;Volum 58.(11) s. 2147-2161
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11 Lund, Jenny; Rustan, Arild; Løvsletten, Nils Gunnar; Mudry, Jonathan M.; Langleite, Torgrim Mikal; Feng, Yuan Zeng; Stensrud, Camilla; Brubak, Mari G; Drevon, Christian A; Birkeland, Kåre I.; Kolnes, Kristoffer Jensen; Johansen, Egil Ivar; Tangen, Daniel S.; Stadheim, Hans Kristian; Gulseth, Hanne Løvdal; Krook, Anna; Kase, Eili Tranheim; Jensen, Jørgen; Thoresen, G. Hege.
Exercise in vivo marks human myotubes in vitro: Training-induced increase in lipid metabolism. PLOS ONE 2017 ;Volum 12:e0175441.(4) s. 1-24
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12 Lund, Jenny; Tangen, Daniel S.; Wiig, Håvard; Stadheim, Hans Kristian; Siw, Anette Helle; Birk, Jesper B.; Ingemann-Hansen, Thorsten; Rustan, Arild; Thoresen, G. Hege; Wojtaszewski, Jørgen F.P.; Kase, Eili Tranheim; Jensen, Jørgen.
Glucose metabolism and metabolic flexibility in cultured skeletal muscle cells is related to exercise status in young male subjects. Archives of Physiology and Biochemistry 2017 ;Volum 124.(2) s. 119-130
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13 Malecki, Jedrzej Mieczyslaw; Jakobsson, Magnus; Ho, Angela Yeuan Yen; Moen, Anders; Rustan, Arild; Falnes, Pål.
Uncovering human METTL12 as a mitochondrial methyltransferase that modulates citrate synthase activity through metabolite-sensitive lysine methylation. Journal of Biological Chemistry 2017 ;Volum 292.(43) s. 17950-17962
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14 Åstrand, Ove Alexander Høgmoen; Viktorsson, Elvar Örn; Kristensen, Aleksander Lim; Ekeberg, Dag; Røberg-Larsen, Hanne; Wilson, Steven Ray Haakon; Gabrielsen, Mari; Sylte, Ingebrigt; Rustan, Arild; Thoresen, G. Hege; Rongved, Pål; Kase, Eili Tranheim.
Synthesis, in vitro and in vivo biological evaluation of new oxysterols as modulators of the liver X receptors. Journal of Steroid Biochemistry and Molecular Biology 2017 ;Volum 165. s. 323-330
OUS UiO UiT NMBU Untitled
 
2016
15 Kong, Xiang Yi; Feng, Yuan Zeng; Eftestøl, Einar; Kase, Eili Tranheim; Haugum, Hanne; Eskild, Winnie; Rustan, Arild; Thoresen, G. Hege.
Increased glucose utilization and decreased fatty acid metabolism in myotubes from Glmpgt/gt mice. Archives of Physiology and Biochemistry 2016 ;Volum 122.(1) s. 36-45
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16 Lund, Jenny; Stensrud, Camilla; Rajender, Melanie Müller; Bohov, Pavol; Thoresen, G. Hege; Berge, Rolf Kristian; Wright, Michael; Kamal, Ahmed; Rustan, Arild; Miller, Andrew D.; Skorve, Jon.
The molecular structure of thio-ether fatty acids influences PPAR-dependent regulation of lipid metabolism. Bioorganic & Medicinal Chemistry 2016 ;Volum 24.(6) s. 1191-1203
HAUKELAND OUS UiB UiO Untitled
 
2015
17 Aas, Vigdis; Lund, Jenny; Kase, Eili Tranheim; Feng, Yuan Zeng; Rustan, Arild; Thoresen, G. Hege.
Blodglukosesenkende legemidler ved type 2-diabetes. Norsk Farmaceutisk Tidsskrift 2015 ;Volum 123.(5) s. 20-24
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18 Bakke, Siril Skaret; Feng, Yuan Zeng; Nikolic, Natasa; Kase, Eili Tranheim; Moro, Cedric; Stensrud, Camilla; Damlien, Lisbeth; Ludahl, Marianne Odnakk; Sandbu, Rune; Solheim, Brita Marie; Rustan, Arild; Hjelmesæth, Jøran; Thoresen, G. Hege; Aas, Vigdis.
Myotubes from Severely Obese Type 2 Diabetic Subjects Accumulate Less Lipids and Show Higher Lipolytic Rate than Myotubes from Severely Obese Non-Diabetic Subjects. PLOS ONE 2015 ;Volum 10.(3)
OSLOMET OUS SIV UiO Untitled
 
19 Coué, Marine; Badin, Pierre-Marie; Vila, Isabelle K.; Laurens, Claire; Louche, Katie; Marquès, Marie-Adeline; Bourlier, Virginie; Mouisel, Etienne; Tavernier, Geneviève; Rustan, Arild; Galgani, Jose E.; Joanisse, Denis R.; Smith, Steven R.; Langin, Dominique; Moro, Cédric.
Defective natriuretic peptide receptor signaling in skeletal muscle links obesity to type 2 diabetes. Diabetes 2015 ;Volum 64.(12) s. 4033-4045
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20 Covington, Jeffrey D.; Myland, Cassandra K.; Rustan, Arild; Ravussin, Eric; Smith, Steven R.; Bajpeyi, Sudip.
Effect of serial cell passaging in the retention of fiber type and mitochondrial content in primary human myotubes. Obesity 2015 ;Volum 23.(12) s. 2414-2420
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21 Covington, Jeffrey D.; Noland, Robert C.; Hebert, R. Caitlin; Masinter, Blaine S.; Smith, Steven R.; Rustan, Arild; Ravussin, Eric; Bajpeyi, Sudip.
Perilipin 3 differentially regulates skeletal muscle lipid oxidation in active, sedentary, and type 2 diabetic males. Journal of Clinical Endocrinology and Metabolism 2015 ;Volum 100.(10) s. 3683-3692
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22 Feng, Yuan Zeng; knabenes, Irlin Knivsland; Bakke, Siril S.; Lund, Jenny; Lee, Y.K.; kimmel, Alan; Thoresen, G. Hege; Rustan, Arild; Dalen, Knut Tomas.
Increased lipid oxidation and decreased lipid storage in myotubes lacking the lipid droplet binding protein perilipin2. Norwegian Biochemical Society Contact Meeting 2015; 2015-02-09 - 2015-02-13
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23 Feng, Yuan Zeng; Nikolic, Natasa; Bakke, Siril Skaret; Kase, Eili Tranheim; Guderud, Kari; Hjelmesæth, Jøran; Aas, Vigdis; Rustan, Arild; Thoresen, G. Hege.
Myotubes from lean and severely obese subjects with and without type 2 diabetes respond differently to an in vitro model of exercise. American Journal of Physiology - Cell Physiology 2015 ;Volum 308.(7) s. C548-C556
OSLOMET OUS SIV UiO Untitled
 
24 Kase, Eili Tranheim; Feng, Yuan Zeng; Badin, Pierre-Marie; Bakke, Siril Skaret; Laurens, C; Coue, M; Langin, Dominique; Gaster, Michael; Thoresen, G. Hege; Rustan, Arild; Moro, Cédric.
Primary defects in lipolysis and insulin action in skeletal muscle cells from type 2 diabetic individuals. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 2015 ;Volum 1851.(9) s. 1194-1201
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25 Kong, Xiang Yi; Kase, Eili Tranheim; Herskedal, Anette; Schjalm, Camilla; Damme, Markus; Nesset, Cecilie Kåsi; Thoresen, G. Hege; Rustan, Arild; Eskild, Winnie.
Lack of the lysosomal membrane protein, GLMP, in mice results in metabolic dysregulation in liver. PLOS ONE 2015 ;Volum 10.(6) s. -
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26 Viktorsson, Elvar Örn; Åstrand, Ove Alexander Høgmoen; Rustan, Arild; Thoresen, G. Hege; Kase, Eili Tranheim; Rongved, Pål.
Analogs of 22-S-hydroxycholesterol as potential Liver X Receptor-modulators: Synthesis and biological evaluation. Organisk Kjemisk Vintermøte 2015; 2015-01-08 - 2015-01-11
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2014
27 Bajpeyi, Sudip; Myrland, Cassandra Kim; Covington, Jeffrey D.; Obanda, Diana; Cefalu, W.T.; Smith, Steven R.; Rustan, Arild; Ravussin, Eric.
Lipid in skeletal muscle myotubes is associated to the donors' insulin sensitivity and physical activity phenotypes. Obesity 2014 ;Volum 22.(2) s. 426-434
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28 Covington, Jeffrey D.; Galgani, Jose E.; Moro, Cedric; LaGrange, Jamie M; Zhang, Zhengyu; Rustan, Arild; Ravussin, Eric; Bajpeyi, Sudip.
Skeletal muscle perilipin 3 and coatomer proteins are increased following exercise and are associated with fat oxidation. PLOS ONE 2014 ;Volum 9.(3)
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29 Feng, Yuan Zeng; knabenes, Irlin Knivsland; Lund, Jenny; Lee, Y.K.; kimmel, Alan; Thoresen, G. Hege; Rustan, Arild; Dalen, Knut Tomas.
Increased lipid oxidation and decreased lipid storage in myotubes lacking perilipin2. The NBS Contact Meeting 2014; 2014-01-23 - 2014-01-26
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30 Feng, Yuan Zeng; Nikolic, Natasa; Bakke, Siril Skaret; Boekschoten, Mark V.; Kersten, Sander; Kase, Eili Tranheim; Rustan, Arild; Thoresen, G. Hege.
PPARδ activation in human myotubes increases mitochondrial fatty acid oxidative capacity and reduces glucose utilization by a switch in substrate preference. Archives of Physiology and Biochemistry 2014 ;Volum 120.(1) s. 12-21
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31 Kong, Xiang Yi; Nesset, Cecilie Kåsi; Damme, Markus; Løberg, Else Marit; Lübke, Torben; Mæhlen, Jan; Andersson, Kristin Brevik; Lorenzo, Petra Isabel O.; Roos, Norbert; Thoresen, G. Hege; Rustan, Arild; Kase, Eili Tranheim; Eskild, Winnie.
Loss of lysosomal membrane protein NCU-G1 in mice results in spontaneous liver fibrosis with accumulation of lipofuscin and iron in Kupffer cells. Disease Models and Mechanisms 2014 ;Volum 7.(3) s. 351-362
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32 Kong, Xiang Yi; Nesset, Cecilie Kåsi; Schjalm, Camilla; Løberg, Else Marit; Rustan, Arild; Thoresen, G. Hege; Kase, Eili Tranheim; Eskild, Winnie.
NCU-G1GT/GT MICE: A LONG-LIVED MODEL FOR LIVER FIBROSIS. The International Liver Congress 2014; 2014-04-09 - 2014-04-13
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33 Smith, Robert; Solberg, Rigmor; Jacobsen, Linn Løkken; Voreland, Anette Larsen; Rustan, Arild; Thoresen, G. Hege; Johansen, Harald Thidemann.
Simvastatin inhibits glucose metabolism and legumain activity in human myotubes. PLOS ONE 2014 ;Volum 9.(1:85721) s. -
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34 Åstrand, Ove Alexander Høgmoen; Gikling, Ingveig; Sylte, Ingebrigt; Rustan, Arild; Thoresen, G. Hege; Rongved, Pål; Kase, Eili Tranheim.
Development of new LXR modulators that regulate LXR target genes and reduce lipogenesis in human cell models. European Journal of Medicinal Chemistry 2014 ;Volum 74. s. 258-263
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2013
35 Aas, Vigdis; Bakke, Siril Skaret; Feng, Yuan Zeng; Kase, Eili Tranheim; Jensen, Jørgen; Bajpeyi, Sudip; Thoresen, G. Hege; Rustan, Arild.
Are cultured human myotubes far from home?. Cell and Tissue Research 2013 ;Volum 354.(3) s. 671-682
OSLOMET NIH OUS UiO Untitled
 
36 Covington, Jeffrey D.; Galgani, Jose E.; Rustan, Arild; Zhang, Zhengyu; Moro, Cedric; Smith, Steven R.; Ravussin, Eric; Bajpeyi, S.
Muscle perilipin 3 is reduced using in vitro and in vivo exercise models and negatively associated with exercise lipid oxidation. The FASEB Journal 2013 ;Volum 27. s. -
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37 Kase, Eili Tranheim; Lund, Jenny; Feng, Yuan Zeng; Langleite, Torgrim Mikal; Aas, Vigdis; Jensen, Jan S.; Birkeland, Kåre I.; Gulseth, Hanne Løvdal; Drevon, Christian A; Rustan, Arild; Thoresen, G. Hege.
Effect of exercise on fatty acid and glucose metabolism in cultured human myotubes. Diabetologia 2013 ;Volum 56. s. S250-S250
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38 Kase, Eili Tranheim; Nikolic, Natasa; Bakke, Siril Skaret; Bogen, Kaja Kamilla; Aas, Vigdis; Thoresen, G. Hege; Rustan, Arild.
Remodelling of oxidative energy metabolism by galactose improves glucose handling and metabolic switching in human skeletal muscle cells. PLOS ONE 2013 ;Volum 8.(4) s. -
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39 Smith, Robert; Johansen, Harald Thidemann; Jacobsen, Linn Løkken; Voreland, Anette Larsen; Rustan, Arild; Thoresen, G. Hege; Solberg, Rigmor.
Simvastatin inhibits legumain activity and processing in human myotubes. 8th General Meeting of the International Proteolysis Society; 2013-10-20 - 2013-10-24
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2012
40 Aas, Vigdis; Bakke, Siril Skaret; Nikolic, Natasa; Hjelmesæth, Jøran; Thoresen, G. Hege; Rustan, Arild.
Altered energy metabolism in skeletal muscle cells derived from morbidly obese subjects. EASD 48th Meeting; 2012-10-01 - 2012-10-05
OSLOMET SIV UiO Untitled
 
41 Badin, Pierre-Marie; Loubière, Camille; Coonen, Maarten; Louche, Katie; Tavernier, Geneviève; Bourlier, Virginie; Mairal, Aline; Rustan, Arild; Smith, Steven R.; Langin, Dominique; Moro, Cedric.
Regulation of skeletal muscle lipolysis and oxidative metabolism by the co-lipase CGI-58. Journal of Lipid Research 2012 ;Volum 53.(5) s. 839-848
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42 Bakke, Siril Skaret; Feng, Yuan Zeng; Rustan, Arild; Hjelmesæth, Jøran; Thoresen, G. Hege; Aas, Vigdis.
Lower lipolysis to counteract the development of type 2 diabetes mellitus - evidence from myotubes established from extremely obese subjects. Diabetesforskningskonferansen 2012; 2012-11-15 - 2012-11-16
OSLOMET SIV UiO Untitled
 
43 Bakke, Siril Skaret; Moro, Cedric; Nikolic, Natasa; Hessvik, Nina Pettersen; Badin, Pierre-Marie; Lauvhaug, Line; Fredriksson, Katarina; Hesselink, Matthijs K. C.; Boekschoten, Mark V.; Kersten, Sander; Gaster, Michael; Thoresen, G. Hege; Rustan, Arild.
Palmitic acid follows a different metabolic pathway than oleic acid in human skeletal muscle cells; lower lipolysis rate despite an increased level of adipose triglyceride lipase. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 2012 ;Volum 1821.(10) s. 1323-1333
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44 Bakke, Siril Skaret; Nikolic, Natasa; Rustan, Arild; Hjelmesæth, Jøran; Thoresen, G. Hege; Aas, Vigdis.
Altered energy metabolism in skeletal muscle cells derived from morbidly obese donors. Genetic and Molecular Basis of Obesity and Body Weight Regulation; 2012-01-29 - 2012-02-03
OSLOMET SIV UiO Untitled
 
45 Bakke, Siril Skaret; Nikolic, Natasa; Rustan, Arild; Hjelmesæth, Jøran; Thoresen, G. Hege; Aas, Vigdis.
ALTERED ENERGY METABOLISM IN SKELETAL MUSCLE CELLS DERIVED FROM MORBIDLY OBESE INDIVIDUALS. European Congress on Obesity (ECO); 2012-05-09 - 2012-05-12
OSLOMET SIV UiO Untitled
 
46 Fraser, David; Hessvik, Nina Pettersen; Nikolic, Natasa; Aas, Vigdis; Hanssen, Kristian Folkvord; Bøhn, Siv Kjølsrud; Thoresen, G. Hege; Rustan, Arild.
Benfotiamine increases glucose oxidation and downregulates NADPH oxidase 4 expression in cultured human myotubes exposed to both normal and high glucose concentrations. Genes & Nutrition 2012 s. -
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47 Hessvik, Nina Pettersen; Bakke, Siril Skaret; Smith, Robert; Ravna, aina westrheim; Sylte, Ingebrigt; Rustan, Arild; Thoresen, G. Hege; Kase, Eili Tranheim.
The liver X receptor modulator 22(S)-hydroxycholesterol exerts cell-type specific effects on lipid and glucose metabolism. Journal of Steroid Biochemistry and Molecular Biology 2012 ;Volum 128. s. 154-164
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48 Kase, Eili Tranheim; Nikolic, Natasa; Hessvik, Nina Pettersen; Fjeldheim, Åse-Karine; Jensen, Jørgen; Thoresen, G. Hege; Rustan, Arild.
Dietary supplementation with 22-S-hydroxycholesterol to rats reduces body weight gain and the accumulation of liver triacylglycerol. Lipids 2012 ;Volum 47.(5) s. 483-493
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49 Nikolic, Natasa; Bakke, Siril Skaret; Kase, Eili Tranheim; Rudberg, Ida; Halle, Ingeborg Flo; Rustan, Arild; Thoresen, G. Hege; Aas, Vigdis.
Electrical Pulse Stimulation of Cultured Human Skeletal Muscle Cells as an In Vitro Model of Exercise. PLOS ONE 2012 ;Volum 7.(3)
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50 Nikolic, Natasa; Rhedin, M; Rustan, Arild; Storlien, Len H.; Thoresen, G. Hege; Strømstedt, Maria.
Overexpression of PGC-1α Increases Fatty Acid Oxidative Capacity of Human Skeletal Muscle Cells. Biochemistry Research International 2012 ;Volum 2012. s. -
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