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2021
1 Davidsen, Nichlas; Lauvås, Anna Jacobsen; Myhre, Oddvar; Ropstad, Erik; Carpi, Donatella; Mendoza-de Gyves, Emilio; Berntsen, Hanne Friis; Dirven, Hubert; Paulsen, Ragnhild Elisabeth; Bal-Price, Anna; Pistollato, Francesca.
Exposure to human relevant mixtures of halogenated persistent organic pollutants (POPs) alters neurodevelopmental processes in human neural stem cells undergoing differentiation. Reproductive Toxicology 2021 ;Volum 100. s. 17-34
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2 Lindeman, Birgitte; Johansson, Ylva; Andreassen, Mathilda; Husøy, Trine; Dirven, Hubert; Hofer, Tim; Knutsen, Helle Katrine; Caspersen, Ida Henriette; Vejrup, Kristine; Paulsen, Ragnhild Elisabeth; Alexander, Jan; Forsby, Anna; Myhre, Oddvar.
Does the food processing contaminant acrylamide cause developmental neurotoxicity? A review and identification of knowledge gaps. Reproductive Toxicology 2021 ;Volum 101. s. 93-114
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3 Yadav, Ajay; Verhaegen, Steven; Verbruggen, Evelien; Kerhoas, Marie; Huiberts, Eva Henriëtte Willemijn; Hadera, Mussie Ghezu; Berntsen, Hanne Friis; Zimmer, Karin Elisabeth; Ropstad, Erik; Paulsen, Ragnhild Elisabeth.
A human relevant mixture of persistent organic pollutants (POPs) and perfluorooctane sulfonic acid (PFOS) differentially affect glutamate induced excitotoxic responses in chicken cerebellum granule neurons (CGNs) in vitro. Reproductive Toxicology 2021
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2020
4 Berntsen, Hanne Friis; Duale, Nur; Bjørklund, Cesilie Granum; Rangel-Huerta, Oscar Daniel; Dyrberg, Kine; Hofer, Tim; Rakkestad, Kirsten Eline; Østby, Gunn Charlotte; Halsne, Ruth; Boge, Gudrun Seeberg; Paulsen, Ragnhild Elisabeth; Myhre, Oddvar; Ropstad, Erik.
Effects of a human-based mixture of persistent organic pollutants on the in vivo exposed cerebellum and cerebellar neuronal cultures exposed in vitro. Environment International 2020 ;Volum 146.
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5 Berntsen, Hanne Friis; Moldes-Anaya, Angel; Bjørklund, Cesilie Granum; Ragazzi, Lorenzo; Haug, Trude M; Strandabø, Rønnaug; Verhaegen, Steven; Paulsen, Ragnhild Elisabeth; Ropstad, Erik; Tasker, Andrew.
Perfluoroalkyl acids potentiate glutamate excitotoxicity in rat cerebellar granule neurons. Toxicology 2020 ;Volum 445. s. -
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6 Evjen, Sigvart; Åstrand, Ove Alexander Høgmoen; Gaarder, Mona; Paulsen, Ragnhild Elisabeth; Fiksdahl, Anne; Knuutila, Hanna K.
Degradative behavior and toxicity of alkylated imidazoles. Industrial & Engineering Chemistry Research 2020 ;Volum 59.(2) s. 587-595
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7 Yadav, Ajay; Amber, Mazia; Zosen, Denis; Labba, Nils Anders; Huiberts, Eva Henriette Willemijn; Samulin-Erdem, Johanna Maria; Haugen, Fred; Berntsen, Hanne Friis; Zienolddiny, Shanbeh; Paulsen, Ragnhild Elisabeth; Ropstad, Erik; Connolly, Lisa; Verhaegen, Steven.
A human relevant mixture of persistent organic pollutants (POPs) and perfluorooctane sulfonic acid (PFOS) enhance nerve growth factor (NGF)-induced neurite outgrowth in PC12 cells. Toxicology Letters 2020 ;Volum 338. s. 85-96
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2019
8 Fjelldal, Marthe Fredheim; Freyd, Thibaud; Evenseth, Linn; Sylte, Ingebrigt; Ring, Avi; Paulsen, Ragnhild Elisabeth.
Exploring the overlapping binding sites of ifenprodil and EVT‐101 in GluN2B‐containing NMDA receptors using novel chicken embryo forebrain cultures and molecular modeling. Pharmacology Research & Perspectives 2019 ;Volum 7.(3) s. 1-15
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9 Fjelldal, Marthe Fredheim; Hadera, Mussie Ghezu; Kongstorp, Mette; Austdal, Lars Peter Engeset; Sulovic, Ana; Andersen, Jannike Mørch; Paulsen, Ragnhild Elisabeth.
Opioid receptor-mediated changes in the NMDA receptor in developing rat and chicken. International Journal of Developmental Neuroscience 2019 ;Volum 78.(C) s. 19-27
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2018
10 Berntsen, Hanne Friis; Bjørklund, Cesilie Granum; Strandabø, Rønnaug; Haug, Trude; Moldes-Anaya, Angel; Fuentes-Lazaro, Judit; Verhaegen, Steven; Paulsen, Ragnhild Elisabeth; Tasker, R. Andrew; Ropstad, Erik.
PFOS-induced excitotoxicity is dependent on Ca2+ influx via NMDA receptors in rat cerebellar granule neurons. Toxicology and Applied Pharmacology 2018 ;Volum 357. s. 19-32
STAMI UiO UiT NMBU UNN Untitled
 
11 Myhre, Oddvar; Låg, Marit; Villanger, Gro Dehli; Oftedal, Bente Margaret; Øvrevik, Johan; Holme, Jørn Andreas; Aase, Heidi; Paulsen, Ragnhild Elisabeth; Bal-Price, Anna; Dirven, Hubert.
Early life exposure to air pollution particulate matter (PM) as risk factor for attention deficit/hyperactivity disorder (ADHD): Need for novel strategies for mechanisms and causalities. Toxicology and Applied Pharmacology 2018 ;Volum 354. s. 196-214
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12 Stahl, Katja; Rahmani, Soulmaz; Prydz, Agnete; Skauli, Nadia; MacAulay, Nanna; Mylonakou, Maria-Niki; Torp, Reidun; Skare, Øivind; Berg, Torill; Leergaard, Trygve Brauns; Paulsen, Ragnhild Elisabeth; Ottersen, Ole Petter; Amiry-Moghaddam, Mahmood.
Targeted deletion of the aquaglyceroporin AQP9 is protective in a mouse model of Parkinson's disease. PLOS ONE 2018 ;Volum 13.(3)
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13 Sørvik, Irene Beate; Solum, Eirik Johansson; Labba, Nils Anders; Hansen, Trond Vidar; Paulsen, Ragnhild Elisabeth.
Differential effects of some novel synthetic oestrogen analogs on oxidative PC12 cell death caused by serum deprivation. Free radical research 2018 ;Volum 52.(2) s. 273-287
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2017
14 Gervin, Kristina; Nordeng, Hedvig Marie Egeland; Eskeland, Ragnhild; Paulsen, Ragnhild Elisabeth; Lyle, Robert.
Farmakoepigenetikk: Samspillet mellom legemidler og epigenetikk. Norsk Farmaceutisk Tidsskrift 2017 ;Volum 125.(8) s. 30-34
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15 Hadera, Mussie Ghezu; Andersen, Jannike Mørch; Paulsen, Ragnhild Elisabeth.
Effects of methadone in the developing chicken embryo as a model of neurodevelopmental toxicity. Reproductive Toxicology 2017 ;Volum 72. s. 216-217
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16 Rakkestad, Kirsten Eline; Dahl, Jon Einar; Paulsen, Ragnhild Elisabeth; Låg, Marit; Samuelsen, Jan Tore.
Do silica nanoparticles induce oxidative stress by different mechanisms in different mammalian cell lines?. Vintermøte for Norsk Selskap for Farmakologi og Toksikologi; 2017-01-26 - 2017-01-29
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17 Sørvik, Irene Beate; Paulsen, Ragnhild Elisabeth.
High and low concentration of 17?-estradiol protect cerebellar granule neurons in different time windows. Biochemical and Biophysical Research Communications - BBRC 2017 ;Volum 490.(3) s. 676-681
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18 Treimo, Alexandra Isabel Sveinsen; Borgå, Katrine; Samuelsen, Jan Tore; Paulsen, Ragnhild Elisabeth; Rakkestad, Kirsten Eline.
Are nanoparticles used in dental materials neurotoxic?. Vintermøte for Norsk Selskap for Farmakologi og Toksikologi; 2017-01-26 - 2017-01-29
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2016
19 Austdal, Lars Peter Engeset; Bjørnstad, Sigrid; Mathisen, Gro Haarklou; Aden, Petra; Mikkola, Ingvild; Paulsen, Ragnhild Elisabeth; Rakkestad, Kirsten Eline.
Glucocorticoid effects on cerebellar development in a chicken embryo model: exploring changes in PAX6 and Metalloproteinase-9 after exposure to dexamethasone. Journal of neuroendocrinology 2016 ;Volum 28.(12) s. -
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20 Austdal, Lars Peter Engeset; Mathisen, Gro Haarklou; Løberg, Else Marit; Paulsen, Ragnhild Elisabeth.
Calcium-induced apoptosis of developing cerebellar granule neurons depends causally on NGFI-B. International Journal of Developmental Neuroscience 2016 ;Volum 55. s. 82-90
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21 Bjørnstad, Sigrid; Samara, Athina; Erichsen, Aage; Paulsen, Ragnhild Elisabeth; Glover, Joel; Roald, Borghild.
Hampered lung maturation in methimazole-induced hypothyroidism in fetal chicken: morphological and molecular correlates to human fetal development. Neonatology 2016 ;Volum 110.(2) s. 83-92
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2015
22 Bjørnstad, Sigrid; Austdal, Lars Peter Engeset; Roald, Borghild; Glover, Joel; Paulsen, Ragnhild Elisabeth.
Cracking the egg: potential of the developing chicken as a model system for nonclinical safety studies of pharmaceuticals. Journal of Pharmacology and Experimental Therapeutics 2015 ;Volum 355. s. 386-396
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23 Yazdani, Mazyar; Paulsen, Ragnhild Elisabeth; Gjøen, Tor; Hylland, Ketil.
Reactive Oxygen Species and Cytotoxicity in Rainbow Trout Hepatocytes: Effects of Medium and Incubation Time. Bulletin of Environmental Contamination and Toxicology 2015 ;Volum 94. s. 193-198
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2014
24 Bjørnstad, Sigrid; Paulsen, Ragnhild Elisabeth; Erichsen, Aage; Glover, Joel; Roald, Borghild.
Type I and II pneumocyte differentiation in the developing fetal chicken lung: Conservation of pivotal proteins from birds to human in the struggle for life at birth. Neonatology 2014 ;Volum 105.(2) s. 112-120
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25 Rakkestad, Kirsten Eline; Sørvik, Irene Beate; Øverby, Gunn Rebecca; Debernard, Karen A. Boldingh; Mathisen, Gro Haarklou; Paulsen, Ragnhild Elisabeth.
17a-estradiol down-regulates glutathione synthesis in serum deprived PC-12 cells. Free radical research 2014 ;Volum 48.(10) s. 1170-1178
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26 Solum, Eirik Johansson; Cheng, Jing-Jy; Sørvik, Irene Beate; Paulsen, Ragnhild Elisabeth; Vik, Anders; Hansen, Trond Vidar.
Synthesis and biological evaluations of new analogs of 2-methoxyestradiol: Inhibitors of tubulin and angiogenesis. European Journal of Medicinal Chemistry 2014 ;Volum 85. s. 391-398
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2013
27 Aziz, Gulzeb; Odlo, Kristin; Hansen, Trond Vidar; Paulsen, Ragnhild Elisabeth; Mathisen, Gro Haarklou.
Combretastatin A-4 and structurally related triazole analogues induce caspase-3 and reactive oxygen species-dependent cell death in PC12 cells. European Journal of Pharmacology 2013 ;Volum 703.(1-3) s. 25-32
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28 Mathisen, Gro Haarklou; Yazdani, Mazyar; Rakkestad, Kirsten Eline; Aden, Petra; Bodin, Johanna; Samuelsen, Mari; Nygaard, Unni Cecilie; Goverud, Ingeborg Løstegaard; Gaarder, Mona; Løberg, Else Marit; Bølling, Anette Kocbach; Becher, Rune; Paulsen, Ragnhild Elisabeth.
Prenatal exposure to bisphenol A interferes with the development of cerebellar granule neurons in mice and chicken. International Journal of Developmental Neuroscience 2013 ;Volum 31.(8) s. 762-769
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29 Yazdani, Mazyar; Paulsen, Ragnhild Elisabeth; Gjøen, Tor; Hylland, Ketil.
Reactive oxygen species and cytotoxicity in rainbow trout hepatocytes: effects of medium and incubation time. 23rd SETAC Europe annual meeting; 2013-05-12 - 2013-05-16
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30 Åstrand, Ove Alexander; Aziz, Gul zeb; Ali, Sidra Farzand; Paulsen, Ragnhild Elisabeth; Hansen, Trond Vidar; Rongved, Pål.
Synthesis and initial in vitro biological evaluation of two new zinc-chelating compounds: Comparison with TPEN and PAC-1. Bioorganic & Medicinal Chemistry 2013 ;Volum 21.(17) s. 5175-5181
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31 Åstrand, Ove Alexander Høgmoen; Austdal, Lars Peter Engeset; Paulsen, Ragnhild Elisabeth; Hansen, Trond Vidar; Rongved, Pål.
Synthesis and characterization of new selective Zn2+ fluorescent probes for functionalization: in vitro Cell imaging applications. Tetrahedron 2013 ;Volum 49.(40) s. 8645-8654
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2012
32 Bølling, Anette Kocbach; Øvrevik, Johan; Samuelsen, Jan Tore; Holme, Jørn Andreas; Rakkestad, Kirsten Eline; Mathisen, Gro Haarklou; Paulsen, Ragnhild Elisabeth; Korsnes, Monica Suarez; Becher, Rune.
Mono-2-ethylhexylphthalate (MEHP) induces TNF-alpha release and macrophage differentiation through different signalling pathways in RAW264.7 cells. Toxicology Letters 2012 ;Volum 209.(1) s. 43-50
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33 Debernard, Karen A. Boldingh; Mathisen, Gro Haarklou; Paulsen, Ragnhild Elisabeth.
Differences in NGFI-B, Nurr1, and NOR-1 expression and nucleocytoplasmic translocation in glutamate-treated neurons. Neurochemistry International 2012 ;Volum 61.(1) s. 79-88
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34 Strøm, Bjørn Oddvar; Paulsen, Ragnhild Elisabeth.
Apoptosis inducer NGFI-B is degraded by the proteasome and stabilized by treatment with EGF. Biochemical and Biophysical Research Communications - BBRC 2012 ;Volum 417.(4) s. 1292-1297
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2011
35 Aden, Petra; Paulsen, Ragnhild Elisabeth; Mæhlen, Jan; Løberg, Else Marit; Goverud, Ingeborg Løstegaard; Liestøl, Knut; Lømo, Jon.
Glucocorticoids dexamethasone and hydrocortisone inhibit proliferation and accelerate maturation of chicken cerebellar granule neurons. Brain Research 2011 ;Volum 1418. s. 32-41
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36 Debernard, Karen A. Boldingh; Aziz, Gul zeb; Gjesvik, Annine Thomassen; Paulsen, Ragnhild Elisabeth.
Cell death induced by novel procaspase-3 activators can be reduced by growth factors. Biochemical and Biophysical Research Communications - BBRC 2011 ;Volum 413.(2) s. 364-369
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37 Mathisen, Gro Haarklou; Fallgren, Åsa Birgitta; Strøm, Bjørn Oddvar; Debernard, Karen A. Boldingh; Mohebi, Beata Urbanczyk; Paulsen, Ragnhild Elisabeth.
Delayed translocation of NGFI-B/RXR in glutamate stimulated neurons allows late protection by 9-cis retinoic acid. Biochemical and Biophysical Research Communications - BBRC 2011 ;Volum 414.(1) s. 90-95
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38 Yazdani, Mazyar; Paulsen, Ragnhild Elisabeth; Gjøen, Tor; Hylland, Ketil.
Comparison of three fluorescence probes for ROS detection in primary cultures of rainbow trout hepatocytes. Norwegian Society of Pharmacology and Toxicology meeting; 2011-01-12 - 2011-01-15
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2010
39 Aziz, Gulzeb; Akselsen, Øyvind Wilhelm; Hansen, Trond Vidar; Paulsen, Ragnhild Elisabeth.
Procaspase-activating compound 1 induces a caspase-3-dependent cell death in cerebellar granule neurons. Toxicology and Applied Pharmacology 2010 ;Volum 247. s. 238-242
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40 Rakkestad, Kirsten Eline; Holme, Jørn Andreas; Paulsen, Ragnhild E; Schwarze, Per E; Becher, Rune.
Mono(2-ethylhexyl) phthalate induces both pro- and anti-inflammatory responses in rat alveolar macrophages through crosstalk between p38, the lipoxygenase pathway and PPAR alpha. Inhalation Toxicology 2010 ;Volum 22.(2) s. 140-150
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41 Strøm, Bjørn Oddvar; Aden, Petra; Mathisen, Gro Haarklou; Lømo, Jon; Davanger, Svend; Paulsen, Ragnhild Elisabeth.
Transfection of chicken cerebellar granule neurons used to study glucocorticoid receptor regulation by nuclear receptor 4A (NR4A). Journal of Neuroscience Methods 2010 ;Volum 193.(1) s. 39-46
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42 Yazdani, Mazyar; Ellesat, Kathrin; Paulsen, Ragnhild Elisabeth; Hylland, Ketil.
Developing a fish hepatocyte model for oxidative stress studies. SFRR Annual Conference; 2010-09-12 - 2010-09-15
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2008
43 Aden, Petra; Goverud, Ingeborg Løstegaard; Liestøl, Knut; Løberg, Else Marit; Paulsen, Ragnhild Elisabeth; Maehlen, Jan; Lømo, Jon.
Low-potency glucocorticoid hydrocortisone has similar neurotoxic effects as high-potency glucocorticoid dexamethasone on neurons in the immature chicken cerebellum. Brain Research 2008 ;Volum 1236. s. 39-48
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2007
44 Debernard, Karen A. Boldingh; Strøm, Bjørn Oddvar; Jacobs, Chris; Paulsen, Ragnhild Elisabeth.
EGF protects neurons from cell death by ERK2-mediated nuclear targeting of apoptosis-inducer NGFI-B/TR3. Farmakologisk og toksikologis vintermøte; 2007-01-25 - 2007-01-27
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45 Debernard, Karen A. Boldingh; Strøm, Bjørn Oddvar; Jacobs, Chris; Paulsen, Ragnhild Elisabeth.
EGF Protects Neurons From Glutamate-Induced Cell Death by Erk2-Mediated Nuclear Targeting of Apoptosis-Inducer NGFI-B/TR3. Conference on Imaging in Neuroscience; 2007-04-26 - 2007-04-27
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46 Debernard, Karen A. Boldingh; Strøm, Bjørn Oddvar; Jacobs, Chris; Paulsen, Ragnhild Elisabeth.
Vekstfaktoren EGF beskytter nerveceller mot død ved Erk2-mediert kjernelokalisering av apoptose-inducer NGFI-B. Life Science møte; 2007-01-04 - 2007-01-05
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47 Fallgren, Åsa Birgitta; Mathisen, Gro Anita; Mæhlen, Jan; Blomhoff, Rune; Paulsen, Ragnhild Elisabeth.
Preconditioning with estradiol abolishes its neuroprotection in cerebellar neurons. Biochemical and Biophysical Research Communications - BBRC 2007 ;Volum 352. s. 966-972
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48 Maiga, Ababacar Ibrahim; Malterud, Karl Egil; Mathisen, Gro Haarklou; Paulsen, Ragnhild Elisabeth; Thomas-Oates, Jane; Bergström, Ed; Reubsaet, Jan Leo; Diallo, Drissa; Paulsen, Berit Smestad.
Cell protective antioxidants from the root bark of Lannea velutina A. Rich., a Malian medicinal plant. Journal of Medicinal Plants Research 2007 ;Volum 1.(4) s. 66-79
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49 Mathisen, Gro Anita; Fallgren, Åsa Birgitta; Gaarder, Mona; Mæhlen, Jan; Blomhoff, Rune; Paulsen, Ragnhild Elisabeth.
Preconditioning with estradiol abolishes its neuroprotection in cerebellar granule neurons. Farmakologisk og Toksikologisk Vintermøte; 2007-01-25 - 2007-01-28
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50 Mathisen, Gro Anita; Thorkildsen, Inger Helene; Paulsen, Ragnhild Elisabeth.
Secretory PLA(2)-IIA and ROS generation in peripheral mitochondria are critical for neuronal death. Brain Research 2007 ;Volum 1153. s. 43-51
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