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2020
1 Perdreau-Dahl, Harmonie; Progida, Cinzia; Barfeld, Stefan Jörg; Guldsten, Hanne; Thiede, Bernd; Arntzen, Magnus Øverlie; Bakke, Oddmund; Mills, Ian Geoffrey; Krauss, Stefan; Morth, Jens Preben.
Sjögren syndrome/scleroderma autoantigen 1 is a direct Tankyrase binding partner in cancer cells. Communications Biology 2020 ;Volum 3.(1) s. -
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2 Waaler, Jo; Leenders, Ruben G G; Sowa, Sven T.; Brinch, Shoshy Alam; Lycke, Eric Maximilian; Nieczypor, Piotr; Aertssen, Sjoerd; Murthy, Sudarshan; Galera-Prat, Albert; Damen, Eddy; Wegert, Anita; Nazaré, Marc; Lehtiö, Lari; Krauss, Stefan.
Preclinical lead optimization of a 1,2,4-triazole based tankyrase inhibitor. Journal of Medicinal Chemistry 2020 ;Volum 63.(13) s. 6834-6846
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3 Waaler, Jo; Mygland, Line; Tveita, Anders Aune; Strand, Martin Frank; Solberg, Nina; Olsen, Petter Angell; Aizenshtadt, Aleksandra; Fauskanger, Marte; Lund, Kaja; Brinch, Shoshy Alam; Lycke, Max; Dybing, Elisabeth; Nygaard, Vegard; Bøe, Sigurd; Heintz, Karen Marie; Hovig, Eivind; Hammarström, Clara Louise; Corthay, Alexandre; Krauss, Stefan.
Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models. Communications Biology 2020 ;Volum 3.(196) s. -
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2019
4 Brennecke, Philip; Rasina, Dace; Aubi Catevilla, Oscar; Herzog, Katja; Landskron, Johannes; Cautain, Bastien; Vicente, Francisca; Quintana, Jordi; Mestres, Jordi; Stechmann, Bahne; Ellinger, Bernhard; Brea, Jose; Kolanowski, Jacek L.; Pilarski, Radosław; Orzáez, Mar; Pineda-Lucena, Antonio; Laraia, Luca; Nami, Faranak; Zielenkiewicz, Piotr; Paruch, Kamil; Hansen, Espen; von Kries, Jens P.; Neuenschwander, Martin; Specker, Edgar; Bartunek, Petr; Šímová, Šárka; Leśnikowski, Zbigniew; Krauss, Stefan; Lehtiö, Lari; Bilitewski, Ursula; Brönstrup, Mark; Tasken, Kjetil; Jirgensons, Aigars; Lickert, Heiko; Clausen, Mads H.; Andersen, Jeanette hammer; Vicent, Maria J.; Genilloud, Olga; Martinez, Aurora; Nazaré, Marc; Fecke, Wolfgang; Gribbon, Philip.
EU-OPENSCREEN: A novel collaborative approach to facilitate chemical biology. SLAS Discovery 2019 ;Volum 24.(3) s. 398-413
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5 Lin, Ann; Skottvoll, Frøydis Sved; Rayner, Simon; Pedersen-Bjergaard, Stig; Sullivan, Gareth; Krauss, Stefan; Wilson, Steven Ray Haakon; Harrison, Sean.
3D cell culture models and organ-on-a-chip: Meet separation science and mass spectrometry. Electrophoresis 2019 ;Volum 41. s. 56-64
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6 Solberg, Nina; Melheim, Maria; Strand, Martin Frank; Olsen, Petter Angell; Krauss, Stefan.
MEK Inhibition Induces Canonical WNT Signaling through YAP in KRAS Mutated HCT-15 Cells, and a Cancer Preventive FOXO3/FOXM1 Ratio in Combination with TNKS Inhibition. Cancers 2019 ;Volum 11.(2) s. 1-19
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2018
7 Brandtzaeg, Ole Kristian.
Online sample Preparation Platforms for Targeted Nano Liquid Chromatography Mass Spectrometry Bioanalysis. Oslo: Universitetet i Oslo 2018 ;Volum 2018.Series of dissertations submitted to the Faculty of Mathematics and Natural Sciences, University of Oslo.(1968)
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8 Norum, Jens Henrik; Skarpen, Ellen; Brech, Andreas; Kuiper, Raoul; Waaler, Jo; Krauss, Stefan; Sørlie, Therese.
The tankyrase inhibitor G007-LK inhibits small intestine LGR5+ stem cell proliferation without altering tissue morphology. Biological Research (Print) 2018 ;Volum 51.(1) s. -
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9 Skottvoll, Frøydis Sved; Nilsen, Ola; Krauss, Stefan; Sullivan, Gareth; Wilson, Steven Ray Haakon.
Integrating highly miniaturized LC-MS systems with “Organ on a Chip”; the future of preclinical modelling. 23. Norske Symposium i Kromatografi; 2018-01-07 - 2018-01-09
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10 Solberg, Nina Therese; Waaler, Jo; Iversen, Kaja Lund; Mygland, Line; Olsen, Peter Angell; Krauss, Stefan.
TANKYRASE Inhibition Enhances the Antiproliferative Effect of PI3K and EGFR Inhibition, Mutually Affecting β-CATENIN and AKT Signaling in Colorectal Cancer. Molecular Cancer Research 2018 ;Volum 16.(3) s. 1541-
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11 Vehus, Tore.
Nano Liquid Chromatography-Tandem Mass Spectrometry Platforms for Determination of Low Abundant Wnt/Beta-Catenin Proteins in Cancer Research. Oslo: Universitetet i Oslo 2018 ;Volum 2018.Series of dissertations submitted to the Faculty of Mathematics and Natural Sciences, University of Oslo.(1962)
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2017
12 Anumala, Upendra Rao; Waaler, Jo; Nkizinkiko, Yves; Ignatev, Alexander; Lazarow, Katina; Lindemann, Peter; Olsen, Petter Angell; Murthy, Sudarshan; Obaji, Ezeogo; Majouga, Alexander G; Leonov, Sergey; von Kries, Jens Peter; Lehtiö, Lari; Krauss, Stefan; Nazare, Marc.
Discovery of a Novel Series of Tankyrase Inhibitors by a Hybridization Approach. Journal of Medicinal Chemistry 2017 ;Volum 60.(24) s. 10013-10025
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13 Lund, Kaja; Olsen, Cathrine Elisabeth; Wong, Judith Jing Wen; Olsen, Petter Angell; Solberg, Nina Therese; Høgset, Anders; Krauss, Stefan; Selbo, Pål Kristian.
5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin. Journal of Experimental & Clinical Cancer Research 2017 ;Volum 36. s. 1-18
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14 Røberg-Larsen, Hanne; Lund, Kaja; Sæterdal, Kristina Erikstad; Solheim, Stian; Vehus, Tore; Solberg, Nina; Krauss, Stefan; Lundanes, Elsa; Wilson, Steven Ray Haakon.
Mass spectrometric detection of 27-hydroxycholesterol in breast cancer exosomes. Journal of Steroid Biochemistry and Molecular Biology 2017 ;Volum 169. s. 22-28
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15 Solberg, Nina T.; Waaler, Jo; Lund, Kaja; Mygland, Line; Olsen, Petter A.; Krauss, Stefan.
TANKYRASE inhibition enhances the antiproliferative effect of PI3K and EGFR inhibition, mutually affecting β-CATENIN and AKT signaling in colorectal cancer. Molecular Cancer Research 2017 ;Volum 16.(3) s. 543-553
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16 Vehus, Tore; Waaler, Jo; Krauss, Stefan; Lundanes, Elsa; Wilson, Steven Ray Haakon.
Combining HIC, SEC, and IEX with Fluorescence Polarization for Drug Target Discovery. LC GC North America 2017 ;Volum 30.(5) s. 232-239
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2016
17 Haikarainen, Teemu; Waaler, Jo; Ignatev, Alexander; Nkizinkiko, Yves; Venkannagaria, Harikanth; Obaji, Ezeogo; Krauss, Stefan; Lehtiö, Lari.
Development and structural analysis of adenosine site binding tankyrase inhibitors. Bioorganic & Medicinal Chemistry Letters 2016 ;Volum 26.(2) s. 328-333
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18 Røberg-Larsen, Hanne; Lund, Kaja; Sæterdal, Kristina Erikstad; Solheim, Stian; Vehus, Tore; Solberg, Nina; Krauss, Stefan; Lundanes, Elsa; Wilson, Steven Ray Haakon.
Capillary LC mass spectrometric detection of 27-hydroxycholesterol in breast cancer exosomes. 22 norske kromatografi symposium; 2016-01-10 - 2016-01-12
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19 Røberg-Larsen, Hanne.
High sensitivity measurements of side-chain oxysterols using liquid chromatography mass spectrometry. : Universitetet i Oslo 2016 Series of dissertations submitted to the Faculty of Mathematics and Natural Sciences, University of Oslo.(?)
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20 Sæterdal, Kristina E.; Vehus, Tore; Røberg-Larsen, Hanne; Krauss, Stefan; Lundanes, Elsa; Wilson, Steven Ray Haakon.
CYP27A1 – its relation to oxysterols and cancer, and analytical challenges. 22. Norske symposium i kromatografi; 2016-01-10 - 2016-01-12
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21 Sæterdal, Kristina Erikstad.
Determination of CYP27a1 in biological samples using nano liquid chromatography mass spectrometry. : Universitetet i Oslo 2016 107 s.
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22 Vehus, Tore; Røberg-Larsen, Hanne; Waaler, Jo; Aslaksen, Sigrid; Krauss, Stefan; Wilson, Steven Ray Haakon; Lundanes, Elsa.
Versatile, sensitive liquid chromatography mass spectrometry–Implementation of 10 μm OT columns suitable for small molecules, peptides and proteins. Scientific Reports 2016 ;Volum 6. s. -
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23 Vehus, Tore; Sæterdal, Kristina Erikstad; Krauss, Stefan; Lundanes, Elsa; Wilson, Steven Ray Haakon.
Comparison of commercial nanoliquid chromatography columns for fast, targeted mass spectrometry-based proteomics. Future science OA 2016 ;Volum 2.(2)
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2015
24 Brandtzæg, Ole Kristian Merkesvik; Hustoft, Hanne Kolsrud; Vehus, Tore; Greibrokk, Tyge; Krauss, Stefan; Reubsaet, Leon; Lundanes, Elsa; Wilson, Steven Ray Haakon.
On-line protein digestion and peptide separation using “ultra-nano” LC-MS. 15th Nordic Conference in Mass Spectrometry; 2015-01-20 - 2015-01-23
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25 Lund, Kaja; Dembinski, Jennifer Lynn; Solberg, Nina; Urbanucci, Alfonso; Mills, Ian Geoffrey; Krauss, Stefan.
Slug-dependent upregulation of L1CAM is responsible for the increased invasion potential of pancreatic cancer cells following long-term 5-FU treatment. PLOS ONE 2015 ;Volum 10.(4)
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26 Machon, Ondrej; Masek, Jan; Machonova, Olga; Krauss, Stefan; Kozmik, Zbynek.
Meis2 is essential for cranial and cardiac neural crest development. BMC Developmental Biology 2015 ;Volum 15.
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27 Olsen, Peter Angell; Lund, Kaja; Krauss, Stefan.
Expression profiling of wild type and β-catenin gene disrupted human BxPC-3 pancreatic adenocarcinoma cells. Genomics Data 2015 ;Volum 4. s. 150-152
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28 Røberg-Larsen, Hanne; Lund, Kaja; skottvoll, Frøydis S; Krauss, Stefan; Lundanes, Elsa; Wilson, Steven Ray Haakon.
Oxysterols in exosomes. 5th ENOR meeting; 2015-09-24 - 2015-09-25
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29 Thorvaldsen, Tor Espen; Pedersen, Nina Marie; Wenzel, Eva; Schultz, Sebastian; Brech, Andreas; Liestøl, Knut; Waaler, Jo; Krauss, Stefan; Stenmark, Harald Alfred.
Structure, dynamics, and functionality of tankyrase inhibitor-induced degradasomes. Molecular Cancer Research 2015 ;Volum 13.(11) s. 1487-1501
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30 Zhong, Linlin; Ding, Yun; Bandyopadhyay, Gautam; Waaler, Jo; Börgeson, Emma; Smith, Susan; Zhang, Mingchen; Phillips, Susan A.; Mahooti, Sepi; Mahata, Sushil K.; Shao, Jianhua; Krauss, Stefan; Chi, Nai-Wen.
The PARsylation activity of tankyrase in adipose tissue modulates systemic glucose metabolism in mice. Diabetologia 2015 ;Volum 59.(3) s. 582-591
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2014
31 Haikarainen, Teemu; Krauss, Stefan; Lehtiö, Lari.
Tankyrases: Structure, function and therapeutic implications in cancer. Current pharmaceutical design 2014 ;Volum 20.(41) s. 6472-6488
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32 Hustoft, Hanne Kolsrud; Vehus, Tore; Brandtzæg, Ole Kristian Merkesvik; Krauss, Stefan; Greibrokk, Tyge; Wilson, Steven Ray Haakon; Lundanes, Elsa.
Open tubular lab-on-column/mass spectrometry for targeted proteomics of nanogram sample amounts. PLOS ONE 2014 ;Volum 9.(9)
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33 Lund, Kaja; Bostad, Monica; Skarpen, Ellen; Braunagel, Michael; Kiprijanov, Sergej M.; Krauss, Stefan; Duncan, Alex; Høgset, Anders; Selbo, Pål Kristian.
The novel EpCAM-targeting monoclonal antibody 3-17I linked to saporin is highly cytotoxic after photochemical internalization in breast, pancreas and colon cancer cell lines. mAbs 2014 ;Volum 6.(4) s. 1038-1050
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34 Olsen, Peter Angell; Solberg, Nina; Lund, Kaja; Vehus, Tore; Gelazauskaite, Monika; Wilson, Steven Ray Haakon; Krauss, Stefan.
Implications of targeted genomic disruption of β-catenin in B×PC-3 pancreatic adenocarcinoma cells. PLOS ONE 2014 ;Volum 9.(12)
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35 Røberg-Larsen, Hanne; Krauss, Stefan; Greibrokk, Tyge; Lundanes, Elsa; Wilson, Steven Ray Haakon.
Investigating the Role of Endogenous Small Molecules on the Hedgehog Signal Pathway: Very Sensitive, Highly Automated Nano-LC Based Determination of Oxysterols in Cancer Cells. HPLC 2014, New Orleans,; 2014-05-11 - 2014-05-15
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36 Røberg-Larsen, Hanne; Lund, Kaja; Vehus, Tore; Solberg, Nina; Vesterdal, Caroline; Misaghian, Dorna; Olsen, Peter Angell; Krauss, Stefan; Wilson, Steven Ray Haakon; Lundanes, Elsa.
Highly automated nano-LC/MS-based approach for thousand cell-scale quantification of side chain-hydroxylated oxysterols. Journal of Lipid Research 2014 ;Volum 55.(7) s. 1531-1536
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37 Røberg-Larsen, Hanne; Solberg, Nina; Olsen, Petter Angell; Lund, Kaja; Vesterdal, Caroline; Krauss, Stefan; Lundanes, Elsa; Wilson, Steven Ray Haakon.
High sensitive, automated quantification of hedgehog active oxysterols in 10 000- 80 000 pancreatic cancer cells using nanoLC-MS. 21. Norske symposium i kromatografi i Sandefjord; 2014-01-12 - 2014-01-14
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38 Røberg-Larsen, Hanne; Strand, Martin Frank; Krauss, Stefan; Wilson, Steven Ray Haakon.
Metabolites in vertebrate Hedgehog signaling. Biochemical and Biophysical Research Communications - BBRC 2014 ;Volum 446.(3) s. 669-674
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39 Stratford, Eva Wessel; Daffinrud, Jeanette L.; Munthe, Else; Castro, Russell; Waaler, Jo; Krauss, Stefan; Myklebost, Ola.
The tankyrase-specific inhibitor JW74 affects cell cycle progression and induces apoptosis and differentiation in osteosarcoma cell lines. Cancer Medicine 2014 ;Volum 3.(1) s. 36-46
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2013
40 Lau, Ted; Chan, Emily; Callow, Marinella; Waaler, Jo; Boggs, Jason; Blake, Robert A.; Magnuson, Steven; Sambrone, Amy; Schutten, Melissa; Firestein, Ron; Machon, Ondrej; Korinek, Vladimir; Choo, Edna; Diaz, Dolores; Merchant, Mark; Polakis, Paul; Holsworth, Daniel D.; Krauss, Stefan; Costa, Mike.
A Novel Tankyrase Small-Molecule Inhibitor Suppresses APC Mutation-Driven Colorectal Tumor Growth. Cancer Research 2013 ;Volum 73.(10) s. 3132-3144
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41 Lehtiö, Lari; Chi, Nai-Wen; Krauss, Stefan.
Tankyrases as drug targets. The FEBS Journal 2013 ;Volum 280.(15) s. 3576-3593
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42 Solberg, Nina; Krauss, Stefan.
Luciferase Assay to Study the Activity of a Cloned Promoter DNA Fragment. Methods in molecular biology 2013 ;Volum 977. s. 65-78
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43 Strand, Martin Frank.
Modulating the Hedgehog pathway. Oslo: Universitetet i Oslo 2013 124 s.
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44 Voronkov, Andrey; Holsworth, Daniel D.; Waaler, Jo; Wilson, Steven Ray Haakon; Ekblad, Bie; Perdreau, Harmonie; Dinh, Huyen Mong Thi; Drewes, Gerard; Hopf, Carsten; Morth, Jens Preben; Krauss, Stefan.
Structural Basis and SAR for G007-LK, a Lead Stage 1,2,4-Triazole Based Specific Tankyrase 1/2 Inhibitor. Journal of Medicinal Chemistry 2013 ;Volum 56.(7) s. 3012-3023
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45 Voronkov, Andrey; Krauss, Stefan.
Wnt/beta-Catenin Signaling and Small Molecule Inhibitors. Current pharmaceutical design 2013 ;Volum 19.(4) s. 634-664
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2012
46 Holsworth, Daniel D.; Krauss, Stefan.
Recent Advances in Wnt/beta-Catenin Pathway Small-Molecule Inhibitors. Annual Reports in Medicinal Chemistry 2012 ;Volum 47. s. 393-409
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47 Røberg-Larsen, Hanne; Strand, Martin Frank; Grimsmo, Anders; Olsen, Peter Angell; Dembinski, Jennifer; Rise, Frode; Lundanes, Elsa; Greibrokk, Tyge; Krauss, Stefan; Wilson, Steven Ray Haakon.
High sensitivity measurements of active oxysterols with automated filtration/filter backflush-solid phase extraction-liquid chromatography-mass spectrometry. Journal of Chromatography A 2012 ;Volum 1255. s. 291-297
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48 Solberg, Nina; Machon, Ondrej; Krauss, Stefan.
Characterization and functional analysis of the 5'-flanking promoter region of the mouse Tcf3 gene. Molecular and Cellular Biochemistry 2012 ;Volum 360.(1-2) s. 289-299
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49 Solberg, Nina; Machon, Ondrej; Machonova, Olga; Krauss, Stefan.
Mouse Tcf3 represses canonical Wnt signaling by either competing for beta-catenin binding or through occupation of DNA-binding sites. Molecular and Cellular Biochemistry 2012 ;Volum 365.(1-2) s. 53-63
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50 Waaler, Jo; Machon, Ondrej; Tumova, Lucie; Dinh, Huyen Mong Thi; Korinek, Vladimir; Wilson, Steven Ray Haakon; Paulsen, Jan Erik; Pedersen, Nina Marie; Eide, Tor Jacob; Machonova, Olga; Gradl, Dietmar; Voronkov, Andrey; von Kries, Jens Peter; Krauss, Stefan.
A novel tankyrase Inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice. Cancer Research 2012 ;Volum 72.(11) s. 2822-2832
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