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2020
1 Egeland, Erlend Johannessen; Witczak, Bartlomiej J; Zare, Hasse Khiabani; Christensen, Hege Staaland; Åsberg, Anders; Robertsen, Ida.
Chronic Inhibition of CYP3A is Temporarily Reduced by Each Hemodialysis Session in Patients With End‐Stage Renal Disease. Clinical Pharmacology and Therapeutics 2020 ;Volum 108.(4) s. 866-873
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2 Krogstad, Veronica; Peric, Alexandra; Robertsen, Ida; Kringen, Marianne K.; Vistnes, Maria; Hjelmesæth, Jøran; Sandbu, Rune; Johnson, Line Kristin; Angeles, Philip Carlo Soriano; Jansson-Löfmark, Rasmus; Karlsson, Cecilia; Andersson, Shalini; Åsberg, Anders; Andersson, Tommy B.; Christensen, Hege Staaland.
Correlation of body weight and composition with hepatic activities of cytochrome P450 enzymes. Journal of Pharmaceutical Sciences 2020 ;Volum 110.(1) s. 432-437
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2019
3 Krogstad, Veronica; Peric, Alexandra; Robertsen, Ida; Kringen, Marianne K.; Wegler, Christine; Angeles, Philip Carlo Soriano; Hjelmesæth, Jøran; Karlsson, Cecilia; Andersson, Shalini; Artursson, Per; Åsberg, Anders; Andersson, Tommy B; Christensen, Hege Staaland.
A Comparative Analysis of Cytochrome P450 Activities in Paired Liver and Small Intestinal Samples from Patients with Obesity. Drug Metabolism And Disposition 2019 ;Volum 48.(1) s. 8-17
DIAKON OSLOMET OUS SIV UiO Untitled
 
2018
4 Hjelmesæth, Jøran; Åsberg, Anders; Andersson, Shalini; Sandbu, Rune; Robertsen, Ida; Johnson, Line Kristin; Angeles, Philip Carlo Soriano; Hertel, Jens Kristoffer; Skovlund, Eva; Heijer, Maria; Ek, Anna-Lena; Krogstad, Veronica; Karlsen, Tor-Ivar; Christensen, Hege Staaland; Andersson, Tommy B; Karlsson, Cecilia.
Impact of body weight, low energy diet and gastric bypass on drug bioavailability, cardiovascular risk factors and metabolic biomarkers: protocol for an open, non-randomised, three-armed single centre study (COCKTAIL). BMJ Open 2018 ;Volum 8:e021878.(5) s. 1-10
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5 Krogstad, Veronica; Vethe, Nils Tore; Robertsen, Ida; Hasvold, Grete; Ose, Anne-Marthe Due; Hermann, Monica; Andersen, Anders Mikal; Chan, Wai Joe; Skauby, Morten Heier; Svensson, My Hanna Sofia; Åsberg, Anders; Christensen, Hege Staaland.
Determination of Tacrolimus Concentration and Protein Expression of P-Glycoprotein in Single Human Renal Core Biopsies. Therapeutic Drug Monitoring 2018 ;Volum 40.(3) s. 292-300
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2017
6 Ose, Anne M; Krogstad, Veronica; Hasvold, Grete; Robertsen, Ida; Egeland, Erlend Johannessen; Hermann, Monica; Skauby, Morten Heier; Åsberg, Anders; Christensen, Hege Staaland.
Optimalisering av metode for kvantifisering av CYP3A5 og P_glykoprotein i små nyrebiopsier. Norsk Selskap for Farmakologi og Toksikologi, Vintermøte; 2017-01-26 - 2017-01-29
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7 Vu, Martin; Krogstad, Veronica; Johnson, Line Kristin; Angeles, Philip Carlo S; Hasvold, Grete; Hermann, Monica; Karlsson, Cecilia; Andersson, Shalini; Andersson, Tommy B; Hjelmesæth, Jøran; Åsberg, Anders; Christensen, Hege Staaland; Robertsen, Ida.
Effect of low calorie diet on the absolute bioavailability of midazolam in patients with severe obesity. Norsk Selskap for Farmakologi og Toksikologi, Vintermøte; 2017-01-26 - 2017-01-26
HVL OUS SIV UiO Untitled
 
2016
8 Le, Peter Huy Vo; Robertsen, Ida; Åsberg, Anders; Christensen, Hege Staaland; Hermann, Monica.
Utvikling av en sensitiv LC-MS/MS-metode for å kvantifisere midazolam og metabolitter i pasienter med sykelig overvekt før og etter gastrisk bypass-operasjon. Norsk Selskap for Farmakologi og Toksikologi, Vintermøte; 2016-01-25 - 2016-01-28
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2015
9 Hermann, Monica; Robertsen, Ida; Christensen, Hege Staaland.
Immunologisk aktivitet og biologiske legemidler påvirker legemiddelmetabolisme og -transport. Norsk Farmaceutisk Tidsskrift 2015 ;Volum 123.(6) s. 22-25
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10 Myhrer, Marthe; Krogstad, Veronica; Christensen, Hege Staaland; Reubsaet, Leon; Hermann, Monica.
Kvantifisering av P-glykoprotein i lymfocytter ved bruk av LC-MS/MS. Norsk Selskap for Farmakologi og Toksikologi, Vintermøte; 2015-01-26 - 2015-01-29
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11 Robertsen, Ida; Vethe, Nils Tore; Midtvedt, Karsten; Falck, Pål; Christensen, Hege Staaland; Åsberg, Anders.
Closer to the site of action: everolimus concentrations in peripheral blood mononuclear cells correlate well with whole blood concentrations. Therapeutic Drug Monitoring 2015 ;Volum 37.(5) s. 675-680
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12 Ulvmoen, Anders; Robertsen, Ida; Åsberg, Anders; Christensen, Hege Staaland; Hermann, Monica.
Utvikling av en sensitiv LC-MS/MS-metode for å kvantifisere midazolam og metabolitter in vitro og i sykelig overvektige pasienter. Norsk Selskap for Farmakologi og Toksikologi; 2015-01-26 - 2015-01-29
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2014
13 Ahlsen, Kathrine; Robertsen, Ida; Midtvedt, Karsten; Åsberg, Anders; Christensen, Hege Staaland.
Aktivitet av P-glykoprotein i mononukleære celler fra perifert blod. Vintermøte NSFT; 2014-01-23
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14 Ho, Giang Thanh Thi; Braünlich, Marie; Wangensteen, Helle; Malterud, Karl Egil; Økstad, Ole Andreas Løchen; Christensen, Hege Staaland; Johannesen, Siri; Slimestad, Rune; Barsett, Hilde.
Spennende helseeffekter av aroniabær. Farmasidagene 2014; 2014-11-06 - 2014-11-07
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15 Lilleengen, Anniken; Lunde, Ingrid; Sandbu, Rune; Åsberg, Anders; Christensen, Hege Staaland.
CYP3A4-aktivitet ex vivo i individuelle humane intestinale mikrosomer. Vintermøte NSFT; 2014-01-23
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16 Lunde, Ingrid; Bremer, Sara; Midtvedt, Karsten; Mohebi, Beata Urbanczyk; Husvegg, Miriam Dahl; Bergan, Stein; Åsberg, Anders; Christensen, Hege Staaland.
The influence of CYP3A, PPARA and POR genetic variants on the pharmacokinetics of tacrolimus and cyclosporine in renal transplant recipients. European Journal of Clinical Pharmacology 2014 ;Volum 70.(6) s. 685-693
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2013
17 Barsett, Hilde; Bräunlich, Paula Marie; Wangensteen, Helle; Malterud, Karl Egil; Christensen, Hege Staaland; Johannesen, Siri; Ho, Giang Thanh Thi; Vo, L.V.; Slimestad, Rune.
Bioactive compounds in Aronia melanocarpa berries. Nordic Natural Products Conference; 2013-06-03 - 2013-06-05
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18 Bjøringsøy, Stine Karen.
Ekstrakter av hageblåbær, skogsblåbær, tranebær og tyttebær hemmer CYP3A4 in vitro. Oslo: Universitetet i Oslo 2013 58 s.
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19 Bräunlich, Paula Marie; Christensen, Hege Staaland; Johannesen, Siri; Ho, Giang Thanh Thi; Wangensteen, Helle; Barsett, Hilde.
Complement fixing Activity and in vitro inhibition of cytochrome P450 3A4 by Aronia melanocarpa constituents. 61st International congress and annual meeting of the society for medicinal plant and natural product research; 2013-09-01 - 2013-09-05
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20 Bräunlich, Paula Marie; Christensen, Hege Staaland; Johannesen, Siri; Slimestad, Rune; Wangensteen, Helle; Malterud, Karl Egil; Barsett, Hilde.
In Vitro Inhibition of Cytochrome P450 3A4 by Aronia melanocarpa Constituents. Planta Medica 2013 ;Volum 79.(2) s. 137-141
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21 Dahl, Miriam; Lunde, Ingrid; Mohebi, Beata Urbanczyk; Bremer, Sara; Bergan, Stein; Midtvedt, Karsten; Skottheim, Ine Blankenberg; Sandbu, Rune; Åsberg, Anders; Christensen, Hege Staaland.
Farmakokinetisk betydning av sekvensvarianter i CYP3A4, POR og PPAR-alpha. Vintermøte NSFT; 2013-01-24 - 2013-01-27
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22 Darwich, AS; Pade, D; Rowland-Yeo, K; Jamei, M; Åsberg, Anders; Christensen, Hege Staaland; Ashcroft, DM; Rostami-Hodjegan, Amin.
Application of an in silico physiologically based pharmacokinetic model to simulate oral drug bioavailability of atorvastatin and cyclosporine post bariatric surgery. Clinical Pharmacology and Therapeutics 2013 ;Volum 2. s. E47-
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23 Jakobsen, Gunn Signe; Skottheim, Ine Blankenberg; Sandbu, Rune; Christensen, Hege Staaland; Røislien, Jo; Åsberg, Anders; Hjelmesæth, Jøran.
Long-term effects of gastric bypass and duodenal switch on systemic exposure of atorvastatin. Surgical Endoscopy 2013 ;Volum 27.(6) s. 2094-2101
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24 Jensen, Ben Andre.
Utvikling av kvantitativ proteomikkmetodefor P-glykoprotein i mononukleære celler fra perifert blod. Oslo: Universitetet i Oslo 2013 75 s.
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25 Jensen, Ben Andre; Reubsaet, Leon; Christensen, Hege Staaland; Åsberg, Anders; Hermann, Monica.
Utvikling av kvantitativ proteomikkmetode for måling av P-glykoprotein i lymfocytter isolert fra pasienter. Vintermøte NSFT; 2013-01-24 - 2013-01-27
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26 Robertsen, Ida; Falck, Pål; Andreassen, Arne K.; Næss, Nina Kaajal; Lunder, Niclas; Christensen, Hege Staaland; Gullestad, Lars; Åsberg, Anders.
Endomyocardial, intralymphocyte and whole blood concentrations of ciclosporin A in heart transplant recipients. Transplantation Research 2013 ;Volum 2.(5)
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27 Ulvestad, Maria; Skottheim, Ine Blankenberg; Jakobsen, Gunn Signe; Bremer, Sara; Molden, Espen; Åsberg, Anders; Hjelmesæth, Jøran; Andersson, Tommy B; Sandbu, Rune; Christensen, Hege Staaland.
Impact of OATP1B1, MDR1, and CYP3A4 expression in liver and intestine on interpatient pharmacokinetic variability of atorvastatin in obese subjects. Clinical Pharmacology and Therapeutics 2013 ;Volum 93.(3) s. 275-282
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2012
28 Amundsen, Rune; Åsberg, Anders; Ohm, Ingrid Kristine; Christensen, Hege Staaland.
Cyclosporine A- and tacrolimus-mediated inhibition of CYP3A4 and CYP3A5 in vitro. Drug Metabolism And Disposition 2012 ;Volum 40.(4) s. 655-661
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29 Christensen, Hege Staaland; Hermann, Monica.
Immunological response as a source to variability in drug metabolism and transport. Frontiers in Pharmacology 2012 ;Volum 3.(8) s. 1-10
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30 Hotvedt, Tor Arne; Fleischer, Phillip; Molden, Espen; Åsberg, Anders; Christensen, Hege Staaland.
Cytokiners effekt på CYP3A4-mediert metabolisme av midazolam i THLE-celler. Vintermøte NSFT; 2012-01-26
DIAKON UiO Untitled
 
31 Robertsen, Ida; Falck, Pål; Næss, Nina Kaajal; Andreassen, Arne K.; Gullestad, Lars; Christensen, Hege Staaland; Åsberg, Anders.
Endomyovardial, intralymphocyte and whole blood concentrations of cyclosporine A in heart transplant recipients. ASCPT 2012 Annual meeting; 2012-03-14
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2011
32 Amundsen, Rune; Åsberg, Anders; Ohm, IK; Christensen, Hege Staaland.
Ciklosporin og takrolimus som hemmere av CYP3A4 og CYP3A5. Vintermøte NSFT; 2011-01-27
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33 Christensen, Hege Staaland; Amundsen, Rune; Åsberg, Anders.
Mechanisms involved in the pharmacokinetic interaction between atorvastatin and cyclosporine A. 57. The 12th International Congress of Pharmacology, Therapeutics and Clinical Toxicology; 2011-06-07 - 2011-06-11
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34 Christensen, Hege Staaland; Hestad, Anette Leirvik; Molden, Espen; Mathiesen, Liv.
CYP3A5-mediated metabolism of midazolam in recombinant systems is highly sensitive to NADPH-cytochrome P450 reductase activity. Xenobiotica 2011 ;Volum 41.(1) s. 1-5
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35 Huynh, C; Nordeng, Marit; Skottheim, Ine Blankenberg; Sandbu, Rune; Åsberg, Anders; Christensen, Hege Staaland.
Individuell variasjon i P-glykoprotein uttrykk i ulike deler av mage- og tarmsystemet. Vintermøte NSFT; 2011-01-27
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36 Jensstuen, Ågot K; Robertsen, Ida; Amundsen, Rune; Christensen, Hege Staaland.
CYP3A4-mediert metabolisme av cyklosporin i insektsmikrosomer. Vintermøte NSFT; 2011-01-27
OSLOMET UiO Untitled
 
2010
37 Amundsen, Rune; Christensen, Hege Staaland; Zabihyan, B; Åsberg, Anders.
Cyclosporin A, men ikke takrolimus, hemmer OATP1B1-mediert opptak av atorvastatin. Norsk Selskap for Farmakologi og Toksikologi, Vintermøte; 2010-01-26
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38 Amundsen, Rune; Christensen, Hege Staaland; Zabihyan, Behnaz; Åsberg, Anders.
Cyclosporine A, but not tacrolimus, shows relevant inhibition of OATP1B1-mediated transport of atorvastatin. 16th IUPHAR WorldCongress of Basis and Clinical Pharmacology; 2010-07-17 - 2010-07-23
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39 Amundsen, Rune; Christensen, Hege Staaland; Zabihyan, Behnaz; Åsberg, Anders.
Cyclosporine A, but Not Tacrolimus, Shows Relevant Inhibition of Organic Anion-Transporting Protein 1B1-Mediated Transport of Atorvastatin. Drug Metabolism And Disposition 2010 ;Volum 38.(9) s. 1499-1504
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40 Lund, Cathrine; Christensen, Hege Staaland; Frøyshov, Sten; Jacobsen, Dag.
Toxicokinetics of Diltiazem and Three Metabolites During Acute Life-Threatening Poisoning. Clinical Toxicology 2010 ;Volum 48.(3) s. 281-281
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41 Nguyen, Maria.
Hemming av CYP3A4-metabolisme av ulike bærekstrakter. Oslo: Universitetet i Oslo 2010 77 s.
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42 Ohm, IK; Amundsen, Rune; Christensen, Hege Staaland.
Cyclosporin A som hemmer av CYP3A4 og CYP3A5. Norsk selskap for farmakologi og toksikologi, Vintermøte; 2010-01-26
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43 Skottheim, IB; Jakobsen, Gunn Signe; Stormark, Kjartan; Christensen, H; Hjelmesæth, Jøran; Jenssen, Trond Geir; Åsberg, Anders; Sandbu, Rune.
Significant Increase in Systemic Exposure of Atorvastatin After Biliopancreatic Diversion With Duodenal Switch. Clinical Pharmacology and Therapeutics 2010 ;Volum 87.(6) s. 699-705
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44 Vist, Solveig; Skottheim, Ine Blankenberg; Sandbu, Rune; Åsberg, Anders; Christensen, Hege Staaland.
Uttrykk av CYP3A4 og CYP3A5 i parrede prøver fra GI-traktus og lever fra overvektige personer. Norsk Selskap for Farmakologi og Toksikologi, Vintermøte; 2010-01-26
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2009
45 Christensen, Hege Staaland; Hestad, Anette L; Molden, Espen; Mathiesen, Liv.
Effect of NADPH-cytochrome P450 oxidoreductase on CYP3A5-mediated metabolism of midazolam. Vintermøte farmakologi og toksikologi; 2009-01-22
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46 Christensen, Hege Staaland; Mathiesen, Liv; Postvoll, Lillian Wåge; Winther, Bjørn; Molden, Espen.
Different Enzyme Kinetics of Midazolam in Recombinant CYP3A4 Microsomes from Human and Insect Sources. Drug Metabolism and Pharmacokinetics (DMPK) 2009 ;Volum 24.(3) s. 261-268
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47 Amundsen, Rune; Zabihyan, Behnaz; Christensen, Hege Staaland; Åsberg, Anders.
CYCLOSPORINE A, BUT NOT TACROLIMUS, INHIBITS OATP1B1 MEDIATED TRANSPORT OF ATORVASTATIN. American College of Clinical Pharmacology - Annual meeting; 2009-09-13 - 2009-09-15
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48 Amundsen, Rune; Zabihyan, Behnaz; Christensen, Hege Staaland; Åsberg, Anders.
CYCLOSPORINE A, BUT NOT TACROLIMUS, INHIBITS OATP1B1 MEDIATED TRANSPORT OF ATORVASTATIN. Journal of clinical pharmacology 2009 ;Volum 49.(9) s. 1112-1112
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49 Bakken, Gry Vibeke; Rudberg, Ida; Christensen, Hege Staaland; Molden, Espen; Refsum, Helge; Hermann, Monica.
Metabolism of quetiapine by CYP3A4 and CYP3A5 in presence or absence of cytochrome b5. Drug Metabolism And Disposition 2009 ;Volum 37.(2) s. 254-258
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50 Skottheim, IB; Stormark, KM; Stormark, Kjartan; Christensen, H; Jakobsen, GS; Hjelmesæth, Jøran; Hjelmesæth, Jøran; Jenssen, Trond Geir; Reubsaet, JLE; Sandbu, R; Åsberg, Anders.
Significantly Altered Systemic Exposure to Atorvastatin Acid Following Gastric Bypass Surgery in Morbidly Obese Patients. Clinical Pharmacology and Therapeutics 2009 ;Volum 86.(3) s. 311-318
SIV UiO UiT Untitled
 
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