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2020
1 Ciyow, Nasra; Bosnjak, Tatjana; Nilsen, Hilde; Lunde, Ngoc Nguyen; Johansen, Harald Thidemann; Solberg, Rigmor.
Effekt av teriparatid på differensiering og regulering av cysteinproteaser i osteoblaster. NSFT-vintermøte; 2020-01-23 - 2020-01-26
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2 Mohanachandran, Arthii; Bosnjak, Tatjana; Nilsen, Hilde; Lunde, Ngoc Nguyen; Solberg, Rigmor; Johansen, Harald Thidemann.
Differensiering av RAW264.7 til osteoklaster og karakterisering av cysteinproteaser i osteoklaster. NSFT-vintermøte; 2020-01-23 - 2020-01-26
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3 Olsen, Kristine Løkke; Johansen, Harald Thidemann; Nilsen, Hilde; Solberg, Rigmor; Berg, Kristian.
Effekt av cysteinproteasen legumain på celleviabilitet etter fotodynamisk terapi. NSFT-vintermøte; 2020-01-23 - 2020-01-26
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2019
4 Awale, Mustafa; Bosnjak, Tatjana; Nilsen, Hilde; Solberg, Rigmor; Johansen, Harald Thidemann.
Effekten av kjønnshormoner på differensiering av stamceller til osteoblaster og regulering av cysteinproteasene legumain og cathepsin B. Vintermøte i Norsk selskap for farmakologi og toksikologi; 2019-01-24 - 2019-01-27
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5 Bosnjak, Tatjana; Solberg, Rigmor; Arnekleiv, Guro L.; Nilsen, Hilde; Jafari, Abbas; Bassatne, A.; Fuleihan, G.E.H.; Kassem, Moustapha; Johansen, Harald Thidemann.
Vitamin D3 upregulates legumain in the early phase of osteoblast differentiation. 11th General Meeting of the International Proteolysis Society; 2019-09-29 - 2019-10-04
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6 Bosnjak, Tatjana; Solberg, Rigmor; Hemati, Paya Diana; Jafari, Abbas; Kassem, Moustapha; Johansen, Harald Thidemann.
Lansoprazole inhibits the cysteine protease legumain by binding to the active site. Basic & Clinical Pharmacology & Toxicology 2019 ;Volum 125.(2) s. 89-99
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7 Lunde, Ngoc Dieu Nguyen; Bosnjak, Tatjana; Solberg, Rigmor; Johansen, Harald Thidemann.
Mammalian legumain - A lysosomal cysteine protease with extracellular functions?. Biochimie 2019 ;Volum 166. s. 77-83
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8 Lunde, Ngoc Dieu Nguyen; Gregersen, Ida; Ueland, Thor; Shetelig, Christian; Holm, Sverre; Kong, Xiang Yi; Michelsen, Annika; Otterdal, Kari; Yndestad, Arne; Broch, Kaspar; Gullestad, Lars; Nyman, Tuula Anneli; Bendz, Bjørn; Eritsland, Jan; Hoffmann, Pavel; Skagen, Karolina Ryeng; Gonçalves, Isabel; Nilsson, Jan; Grenegård, Magnus; Poreba, Marcin; Drag, Marcin; Seljeflot, Ingebjørg; Sporsheim, Bjørnar; Espevik, Terje; Skjelland, Mona; Johansen, Harald Thidemann; Solberg, Rigmor; Aukrust, Pål; Björbacka, Harry; Andersen, Geir Øystein; Halvorsen, Bente.
Legumain is upregulated in acute cardiovascular events and associated with improved outcome – potentially related to anti-inflammatory effects on macrophages. Atherosclerosis 2019 s. 1-9
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9 Solberg, Rigmor.
The proteolytic enzyme legumain: Structure and functions. Olav Thon Foundation Award Lecture; 2019-03-07
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2018
10 Abbas, Iram; Nilsen, Hilde; Johansen, Harald Thidemann; Solberg, Rigmor.
Deksametason hemmer differensiering av humane mesenkymale stamceller til osteoblaster og regulerer cysteinproteasene legumain og cathepsin B. NSFT vintermøte; 2018-01-25 - 2018-01-28
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11 Bosnjak, Tatjana; Hemati, Paya Diana; Solberg, Rigmor; Johansen, Harald Thidemann.
Cysteine proteases as Targets for Proton Pump Inhibitors (PPIs). Proteolytic Enzymes and Their Inhibitors Gordon Research Conference; 2018-06-03 - 2018-06-08
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12 Gjonbalaj, Nora; Nilsen, Hilde; Solberg, Rigmor; Johansen, Harald Thidemann.
Effekt av inflammasjon på regulering av cysteinproteasene legumain og cathepsin B under differensiering av humane mesenkymale stamceller til osteoblaster. NSFT vintermøte; 2018-01-25 - 2018-01-28
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13 Lunde, Ngoc Nguyen Dieu; Gregersen, Ida; Holm, Sverre; Michelsen, Annika; Sporsheim, Bjørnar; Espevik, Terje; Solberg, Rigmor; Johansen, Harald Thidemann; Halvorsen, Bente.
Platelet-derived legumain, a cysteine protease involved in atherosclerosis. Proteolytic Enzymes and Their Inhibitors Gordon Research Conference; 2018-06-03 - 2018-06-08
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14 Lunde, Ngoc Nguyen Dieu; Holm, Sverre; Dahl, Tuva Børresdatter; Elyouncha, Inass; Sporsheim, Bjørnar; Gregersen, Ida; Abbas, Azhar; Skjelland, Mona; Espevik, Terje; Solberg, Rigmor; Johansen, Harald Thidemann; Halvorsen, Bente.
Plasma and plaques from patients with carotid atherosclerosis have increased levels of legumain. 24th Annual Scandinavian Atherosclerosis Conference; 2018-04-11 - 2018-04-14
NTNU OSTFSYK UiO Untitled
 
15 Solberg, Rigmor.
Hvordan settes positive dopinganalyser i medisinsk/farmakologisk sammenheng, og hvordan omsettes dette til dom?. 23. Norske Symposium i Kromatografi; 2018-01-07 - 2018-01-07
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2017
16 Arnekleiv, Guro L.; Nilsen, Hilde; Lunde, Ngoc Nguyen Dieu; Solberg, Rigmor; Johansen, Harald Thidemann.
Effekt av vitamin D3 på uttrykk, aktivitet og sekresjon av cysteinproteasen legumain studert i ulike cellemodeller. Norsk selskap for farmakologi og toksikologi (NSFT) vintermøte; 2017-01-26 - 2017-01-29
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17 Bosnjak, Tatjana; Hemati, Paya Diana; Nilsen, Hilde; Solberg, Rigmor; Johansen, Harald Thidemann.
Legumain as a target for proton pump inhibitors (PPIs): Importance for off-target effects of PPIs?. 10th General Meeting of the International Proteolysis Society (IPS); 2017-10-28 - 2017-11-01
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18 Hemati, Paya Diana; Bosnjak, Tatjana; Nilsen, Hilde; Lunde, Ngoc Nguyen Dieu; Johansen, Harald Thidemann; Solberg, Rigmor.
The Proton Pump Inhibitor Lansoprazole Inhibits Protease Activity of Legumain. Norsk selskap for farmakologi og toksikologi (NSFT) vintermøte; 2017-01-26 - 2017-01-29
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19 Jafari, Abbas; Qanie, Diyako; Andersen, Thomas L.; Zhang, Yuxi; Chen, Li; Postert, Benno; Parsons, Stuart; Ditzel, Nicholas; Khosla, Sundeep; Johansen, Harald Thidemann; Kjærsgaard-Andersen, Per; Delaissé, Jean-Marie; Abdallah, Basem M.; Hesselson, Daniel; Solberg, Rigmor; Kassem, Moustapha.
Legumain regulates differentiation fate of human bone marrow stromal cells and is altered in postmenopausal osteoporosis. Stem Cell Reports 2017 ;Volum 8.(2) s. 373-386
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20 Lunde, Ngoc Nguyen Dieu; Haugen, Mads Haugland; Larsen, Kristina Broe Bodin; Damgaard, Ingrid; Pettersen, Solveig; Kasem, Roya; Rut, Wioletta; Drag, Marcin; Poreba, Marcin; Johansen, Harald Thidemann; Solberg, Rigmor.
Glycosylation is important for legumain localization and processing to active forms but not for cystatin E/M inhibitory functions. Biochimie 2017 ;Volum 139. s. 27-37
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21 Lunde, Ngoc Nguyen Dieu; Holm, Sverre; Dahl, Tuva B.; Elyoncha, Inass; Sporsheim, Bjørnar; Gregersen, Ida; Abbas, Azhar; Skjelland, Mona; Espevik, Terje; Solberg, Rigmor; Johansen, Harald Thidemann; Halvorsen, Bente.
Plasma and plaques from patients with carotid atherosclerosis have increased levels of legumain. 10th General Meeting of the International Proteolysis Society (IPS); 2017-10-28 - 2017-11-01
NTNU OSTFSYK UiO Untitled
 
22 Lunde, Ngoc Nguyen Dieu; Holm, Sverre; Dahl, Tuva Børresdatter; Inass, Elyouncha; Sporsheim, Bjørnar; Gregersen, Ida; Abbas, Azhar; Skjelland, Mona; Espevik, Terje; Solberg, Rigmor; Johansen, Harald Thidemann; Halvorsen, Bente.
Increased levels of legumain in plasma and plaques from patients with carotid atherosclerosis. Atherosclerosis 2017 ;Volum 257. s. 216-223
NTNU OSTFSYK OUS RS UiO Untitled
 
23 Solberg, Rigmor; Bosnjak, Tatjana; Nilsen, Hilde; Jafari, Abbas; Kassem, Moustapha; Johansen, Harald Thidemann.
Regulation of legumain and cysteine cathepsins during differentiation of human bone marrow stromal cells towards osteoblasts. 10th General Meeting of the International Proteolysis Society (IPS); 2017-10-28 - 2017-11-01
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2016
24 Abdukadir, Nuriddin; Lunde, Ngoc Nguyen Dieu; Nilsen, Hilde; Solberg, Rigmor; Johansen, Harald Thidemann.
Regulering av cysteinproteaser ved differensiering av monocytter til makrofager. Norsk selskap for farmakologi og toksikologi vintermøte; 2016-01-28 - 2016-07-01
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25 Larsen, Kristina Broe Bodin; Johansen, Harald Thidemann; Solberg, Rigmor; Lunde, Ngoc Nguyen Dieu.
Betydning av glykosylering for internalisering og aktivering av prolegumain i humane tykktarmskreftceller. Norsk selskap for farmakologi og toksikologi vintermøte; 2016-01-28 - 2016-01-31
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26 Lunde, Ngoc Nguyen Dieu; Dahl, Tuva Børresdatter; Abdukadir, Nuriddin; Halvorsen, Bente; Solberg, Rigmor; Johansen, Harald Thidemann.
Increased secretion of legumain from pro-inflammatory M1 compared to M2 macrophages. Gordon Research Conference on Proteolytic Enzymes & Their Inhibitors - Exploring and Exploiting Proteases in Development and Disease; 2016-06-25 - 2016-07-01
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27 Poreba, Marcin; Solberg, Rigmor; Rut, Wioletta; Lunde, Ngoc Nguyen Dieu; Kasperkiewicz, Paulina; Snipas, Scott J.; Mihelic, Marko; Turk, Dusan; Turk, Boris; Salvesen, Guy S.; Drag, Marcin.
Counter selection substrate library strategy for developing specific protease substrates and probes. Cell Chemical Biology 2016 ;Volum 23.(8) s. 1023-1034
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28 Røsjø, Bjarne; Solberg, Rigmor.
Desillusjonert over dopingbruken i idretten. titan.uio.no [Internett] 2016-11-21
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29 Solberg, Rigmor; Johansen, Harald Thidemann.
Involvement of the cysteine protease legumain in human health and disease. Scientific Colaboration Meeting; 2016-03-16 - 2016-03-16
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30 Solberg, Rigmor; Rut, Wioletta; Lunde, Ngoc Nguyen Dieu; Kasperkiewicz, Paulina; Snipas, Scott J.; Mihelic, Marko; Turk, Dusan; Turk, Boris; Salvesen, Guy S.; Drag, Marcin; Poreba, Marcin.
New Selective Probes to Inhibit and Image Legumain in Living Cells. Cystatins Meeting 2016; 2016-06-02 - 2016-06-04
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2015
31 Johansen, Harald Thidemann; Elyouncha, Inass; Lunde, Ngoc Nguyen Dieu; Williams, Rich; Solberg, Rigmor; Nilsen, Hilde; Halvorsen, Bente.
Opposing effects of glucose on legumain and cysteine cathepsins. 9th General Meeting of the International Proteolysis Society; 2015-10-04 - 2015-10-08
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32 Lunde, Ngoc Nguyen Dieu; Nilsen, Hilde; Damgaard, Ingrid; Kasem, Roya; Solberg, Rigmor; Haugen, Mads Haugland; Johansen, Harald Thidemann.
Importance of glycosylation for legumain and cystatin E/M functions. 9th General Meeting of the International Proteolysis Society; 2015-10-04 - 2015-10-08
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33 Solberg, Rigmor.
Novel legumain specific cell-permeable activity based probes. Pacific Coast Protease Spring School; 2015-05-03 - 2015-05-06
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34 Solberg, Rigmor; Poreba, Marcin; Rut, Wioletta; Kasperkiewicz, Paulina; Snipas, Scott; Turk, Boris; Salvesen, Guy; Drag, Marcin.
Novel legumain-specific activity based probes binds and inhibits legumain in living cells. 9th General Meeting of the International Proteolysis Society; 2015-10-04 - 2015-10-08
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2014
35 Berven, Lise; Solberg, Rigmor; Samuelsen, Anne Berit C..
Effects of alginates on legumain Activity in RAW 264.7 cells and on prolegumain autoactivation. Planta Medica 2014 ;Volum 80.(16) s. 1358-1358
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36 Smith, Robert; Solberg, Rigmor; Jacobsen, Linn Løkken; Voreland, Anette Larsen; Rustan, Arild; Thoresen, G. Hege; Johansen, Harald Thidemann.
Simvastatin inhibits glucose metabolism and legumain activity in human myotubes. PLOS ONE 2014 ;Volum 9.(1:85721) s. -
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37 Smith, Robert; Åstrand, Ove Alexander Høgmoen; Nguyen, Luan Minh; Elvestrand, Tina; Hagelin, Gunnar; Solberg, Rigmor; Johansen, Harald Thidemann; Rongved, Pål.
Synthesis of a novel legumain-cleavable colchicine prodrug with cell-specific toxicity. Bioorganic & Medicinal Chemistry 2014 ;Volum 22.(13) s. 3309-3315
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38 Solberg, Rigmor; Smith, Robert; Almlöf, Maria; Tewolde, Eyassu Araia; Nilsen, Hilde; Johansen, Harald Thidemann.
Atorvastatin inhibits processing, activity and secretion of legumain in macrophages. Biological chemistry 2014 ;Volum 396.(1) s. 71-80
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39 Solberg, Rigmor; Smith, Robert; Almlöf, Maria; Tewolde, Eyassu Araia; Nilsen, Hilde; Johansen, Harald Thidemann.
Legumain expression, activity and secretion are increased during monocyte-to-macrophage differentiation and inhibited by atorvastatin. Biological chemistry 2014 ;Volum 396.(1) s. 71-80
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2013
40 Berven, Lise; Johansen, Harald Thidemann; Solberg, Rigmor; Kolset, Svein Olav; Samuelsen, Anne Berit C..
Autoactivation of prolegumain is accelerated by glycosaminoglycans. Biochimie 2013 ;Volum 95.(4) s. 772-781
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41 Berven, Lise; Solberg, Rigmor; Truong, Hoa Hong Thi; Arlov, Øystein; Aachmann, Finn Lillelund; Skjåk-Bræk, Gudmund; Jacobsen, Wolfgang Mathias; Johansen, Harald Thidemann; Samuelsen, Anne Berit C..
Alginates induce legumain activity in RAW 264.7 cells and accelerate autoactivation of prolegumain. Bioactive Carbohydrates and Dietary Fibre 2013 ;Volum 2. s. 30-44
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42 Haugen, Mads Haugland; Flatmark, Kjersti; Tamhane, Tripti; Boye, Kjetil; Pettersen, Solveig; Solberg, Rigmor; Johansen, Harald Thidemann; Brix, Klaudia; Mælandsmo, Gunhild.
Nuclear localized legumain in colorectal cancer. 30th Winter School on Proteinases and Inhibitors; 2013-02-27 - 2013-03-03
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43 Haugen, Mads Haugland; Johansen, Harald Thidemann; Pettersen, Solveig; Solberg, Rigmor; Brix, Klaudia; Flatmark, Kjersti; Mælandsmo, Gunhild.
Nuclear Legumain Activity in Colorectal Cancer. PLOS ONE 2013 ;Volum 8.(1)
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44 Johansen, Harald Thidemann; Solberg, Rigmor; Nilsen, Hilde; Smith, Robert.
Effects and interplay of legumain and cystatin E/M om migration and invasion of macrophages. 4th FEBS Advanced Lecture Course; FEBS - MPST 2013; 2013-09-26 - 2013-10-01
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45 Smith, Robert; Johansen, Harald Thidemann; Jacobsen, Linn Løkken; Voreland, Anette Larsen; Rustan, Arild; Thoresen, G. Hege; Solberg, Rigmor.
Simvastatin inhibits legumain activity and processing in human myotubes. 8th General Meeting of the International Proteolysis Society; 2013-10-20 - 2013-10-24
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46 Smith, Robert; Johansen, Harald Thidemann; Nilsen, Hilde; Solberg, Rigmor.
Effects and interplay of legumain and cystatin E/M on migration and invasion of macrophages. 8th General Meeting of the International Proteolysis Society; 2013-10-20 - 2013-10-24
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47 Tina, Elvestrand; Åstrand, Ove Alexander; Smith, Robert; Rongved, Pål; Nilsen, Hilde; Solberg, Rigmor; Johansen, Harald Thidemann.
Cellular effects of a colchicine-prodrug cleaved by legumain. Vintermøte i Norsk Selskap for Farmakologi og Toksikologi (NSFT); 2013-01-24 - 2013-01-27
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48 Voreland, Anette; Smith, Robert; Thoresen, G. Hege; Johansen, Harald Thidemann; Solberg, Rigmor.
The cysteine protease legumain is downregulated by simvastatin in primary human skeletal muscle cells. Vintermøte i Norsk Selskap for Farmakologi og Toksikologi (NSFT); 2013-01-24 - 2013-01-27
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49 Ånonsen, Kjersti Bergh; Nilsen, Hilde; Smith, Robert; Johansen, Harald Thidemann; Solberg, Rigmor.
Regulering av legumain i samspillet mellom makrofager og kreftceller. Vintermøte i Norsk Selskap for Farmakologi og Toksikologi (NSFT); 2013-01-24 - 2013-01-27
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2012
50 Berven, Lise; Johansen, Harald Thidemann; Solberg, Rigmor; Kolset, Svein Olav; Samuelsen, Anne Berit C..
INTERACTIONS BETWEEN PROLEGUMAIN AND GLYCOSAMINOGLYCANS. Gordon Research Seminar and Conference on Proteolytic Enzymes & Their Inhibitors; 2012-06-16 - 2012-06-22
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