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Viser treff 1-19 av 19

2019
1 Malecki, Jedrzej Mieczyslaw; Willemen, Hanneke L.D.M.; Pinto, Rita; Ho, Angela Yeuan Yen; Moen, Anders; Eijkelkamp, Niels; Falnes, Pål Øystein.
Human FAM173A is a mitochondrial lysine-specific methyltransferase that targets adenine nucleotide translocase and affects mitochondrial respiration. Journal of Biological Chemistry 2019 ;Volum 294. s. 11654-11664
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2018
2 Jakobsson, Magnus; Malecki, Jedrzej Mieczyslaw; Falnes, Pål Øystein.
Regulation of eukaryotic elongation factor 1 alpha (eEF1A) by dynamic lysine methylation. RNA Biology 2018 ;Volum 15.(3) s. 314-319
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3 Jakobsson, Magnus; Malecki, Jedrzej Mieczyslaw; Halabelian, Levon; Nilges, Benedikt S.; Pinto, Rita; Kudithipudi, Srikanth; Munk, Stephanie; Davydova, Erna; Zuhairi, Fawsi Rahmadiyan; Arrowsmith, Cheryl H; Jeltsch, Albert; Leidel, Sebastian A.; Olsen, Jesper V.; Falnes, Pål Øystein.
The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates. Nature Communications 2018 ;Volum 9:3411. s. 1-15
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4 Malecki, Jedrzej Mieczyslaw; Willemen, Hanneke L.D.M.; Pinto, Rita; Ho, Angela Yeuan Yen; Moen, Anders; Kjønstad, Ingrid Fadum; Burgering, Boudewijn M.T.; Zwartkruis, Fried; Eijkelkamp, Niels; Falnes, Pål Øystein.
Lysine methylation by the mitochondrial methyltransferase FAM173B optimizes the function of mitochondrial ATP synthase. Journal of Biological Chemistry 2018 ;Volum 294.(4) s. 1128-1141
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5 Willemen, Hanneke L.D.M.; Kavelaars, Annemieke; Prado, Judith; Maas, MIrjam; Versteeg, Sabine; Nellissen, Lara J.J.; Tromp, Jeshua; Gonzalez Cano, Rafael; Zhou, Wenjun; Jakobsson, Magnus; Malecki, Jedrzej Mieczyslaw; Posthuma, George; Habib, Abdella; Heijnen, Cobi J.; Falnes, Pål Øystein; Eijkelkamp, Niels.
Identification of FAM173B as a protein methyltransferase promoting chronic pain. PLoS Biology 2018 ;Volum 16.(2) s. -
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2017
6 Jakobsson, Magnus; Malecki, Jedrzej Mieczyslaw; Nilges, Benedikt S.; Moen, Anders; Leidel, Sebastian A.; Falnes, Pål.
Methylation of human eukaryotic elongation factor alpha (eEF1A) by a member of a novel protein lysine methyltransferase family modulates mRNA translation. Nucleic Acids Research 2017 ;Volum 45. s. 8239-8254
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7 Malecka, Agnieszka Maria; Trøen, Gunhild; Tierens, Anne; Østlie, Ingunn; Malecki, Jedrzej Mieczyslaw; Randen, Ulla; Wang, Junbai; Berentsen, Sigbjørn; Tjønnfjord, Geir Erland; Delabie, Jan.
Frequent somatic mutations of KMT2D (MLL2) and CARD11 genes in primary cold agglutinin disease.. British Journal of Haematology 2017 ;Volum 183.(5) s. 838-842
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8 Malecki, Jedrzej Mieczyslaw; Aileni, Vinay Kumar; Ho, Angela Yeuan Yen; Schwarz, Juliane; Moen, Anders; Sørensen, Vigdis; Nilges, Benedikt S.; Jakobsson, Magnus; Leidel, Sebastian A.; Falnes, Pål.
The novel lysine specific methyltransferase METTL21B affects mRNA translation through inducible and dynamic methylation of Lys-165 in human eukaryotic elongation factor 1 alpha (eEF1A). Nucleic Acids Research 2017 ;Volum 45.(8) s. 4370-4389
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9 Malecki, Jedrzej Mieczyslaw; Jakobsson, Magnus; Ho, Angela Yeuan Yen; Moen, Anders; Rustan, Arild; Falnes, Pål.
Uncovering human METTL12 as a mitochondrial methyltransferase that modulates citrate synthase activity through metabolite-sensitive lysine methylation. Journal of Biological Chemistry 2017 ;Volum 292.(43) s. 17950-17962
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2016
10 Falnes, Pål; Jakobsson, Magnus; Davydova, Erna; Ho, Angela Yeuan Yen; Malecki, Jedrzej Mieczyslaw.
Protein lysine methylation by seven-β-strand methyltransferases. Biochemical Journal 2016 ;Volum 473.(14) s. 1995-2009
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11 Malecka, Agnieszka Maria; Trøen, Gunhild; Tierens, Anne; Østlie, Ingunn; Malecki, Jedrzej Mieczyslaw; Randen, Ulla; Berentsen, Sigbjørn; Tjønnfjord, Geir Erland; Delabie, Jan M.A..
Immunoglobulin heavy and light chain gene features are correlated with primary cold agglutinin disease onset and activity. Haematologica 2016 ;Volum 101.(9) s. e361-e364
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12 Malecki, Jedrzej Mieczyslaw; Dahl, Helge-Andre; Moen, Anders; Davydova, Erna; Falnes, Pål.
The METTL20 homologue from agrobacterium tumefaciens is a dual specificity protein-lysine methyltransferase that targets ribosomal protein L7/L12 and the β subunit of electron transfer flavoprotein (ETFβ). Journal of Biological Chemistry 2016 ;Volum 291.(18) s. 9581-9595
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2015
13 Jakobsson, Magnus; Davydova, Erna; Malecki, Jedrzej Mieczyslaw; Moen, Anders; Falnes, Pål.
Saccharomyces cerevisiae eukaryotic elongation factor 1A (eEF1A) is methylated at Lys-390 by a METTL21-like methyltransferase. PLOS ONE 2015 ;Volum 10.(6)
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14 Malecki, Jedrzej Mieczyslaw; Ho, Angela Yeuan Yen; Moen, Anders; Dahl, Helge-Andre; Falnes, Pål.
Human METTL20 is a mitochondrial lysine methyltransferase that targets the β subunit of electron transfer flavoprotein (ETFβ) and modulates its activity. Journal of Biological Chemistry 2015 ;Volum 290.(1) s. 423-434
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2014
15 Davydova, Erna; Ho, Angela Yeuan Yen; Malecki, Jedrzej Mieczyslaw; Moen, Anders; Enserink, Jorrit; Jakobsson, Magnus; Loenarz, Christoph; Falnes, Pål.
Identification and characterization of a novel evolutionarily conserved lysine-specific methyltransferase targeting eukaryotic translation elongation factor 2 (eEF2). Journal of Biological Chemistry 2014 ;Volum 289.(44) s. 30499-30510
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2008
16 Haugsten, Ellen Margrethe; Malecki, Jedrzej M.; Bjørklund, Sunniva Maria Stordal; Olsnes, Sjur; Wesche, Jørgen.
Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis. Molecular Biology of the Cell 2008 ;Volum 19. s. 3390-3403
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2006
17 Wesche, Jørgen; Malecki, Jedrzej M.; Wiedlocha, Antoni; Skjerpen, Camilla Skiple; Claus, P; Olsnes, Sjur.
FGF-1 and FGF-2 require the cytosolic chaperone Hsp90 for translocation into the cytosol and the cell nucleus. Journal of Biological Chemistry 2006 ;Volum 281. s. 11405-11412
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2005
18 Wesche, Jørgen; Malecki, Jedrzej M.; Wiedlocha, Antoni; Ehsani, Maryam; Nilsen, Trine; Marcinkowska, Ewa; Olsnes, Sjur.
Two nuclear localization signals required for transport from the cytosol to the, nucleus of externally added FGF-1 translocated into cells. Biochemistry (Moscow) 2005 ;Volum 44.
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2002
19 Malecki, Jedrzej M.; Wiedlocha, Antoni; Wesche, Jarlis; Olsnes, Sjur.
Vesicle transmembrane potential is required for translocation to cytosol externally added FGF-1. EMBO Journal 2002 ;Volum 21. s. 4480-4490
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