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2019
1 Mihret, Wude; Brusletto, Berit Sletbakk; Øvstebø, Reidun; Siebke, Anne-Marie; Norheim, Gunnstein; Merid, Yared; Kassu, Afework; Abebe, Workeabeba; Ayele, Samuel; Silamsaw, Mezgebu; Yamuah, Lawrence; Aseffa, Abraham; Petros, Beyene; Caugant, Dominique A; Brandtzæg, Petter.
Molecular studies of meningococcal and pneumococcal meningitis patients in Ethiopia. Innate Immunity 2019 ;Volum 25.(3) s. 158-167
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2018
2 Aass, Hans Christian Dalsbotten; Hellum, Marit Synnøve; Siebke, Anne-Marie; Brandtzæg, Petter; Berg, Jens Petter; Øvstebø, Reidun; Henriksson, Carola.
Whole-blood incubation with the Neisseria meningitidis lpxL1 mutant induces less pro-inflammatory cytokines than the wild type, and IL-10 reduces the MyD88-dependent cytokines. Innate Immunity 2018 ;Volum 24.(2) s. 101-111
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3 Gopinathan, Unni; Redalen, Kathrine; Siebke, Anne-Marie; Kierulf, Peter; Brandtzæg, Petter; Ree, Anne Hansen; Berg, Jens Petter; Øvstebø, Reidun.
Large-scale reduction of tyrosine kinase activities in human monocytes stimulated in vitro with N. meningitidis. PLOS ONE 2018 ;Volum 13.(1)
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2017
4 Brusletto, Berit Sletbakk; Hellerud, Bernt C; Løberg, Else Marit; Goverud, Ingeborg Løstegaard; Vege, Åshild; Berg, Jens Petter; Brandtzæg, Petter; Øvstebø, Reidun.
Traceability and distribution of Neisseria meningitidis DNA in archived post mortem tissue samples from patients with systemic meningococcal disease. BMC Clinical Pathology 2017 ;Volum 17.(1)
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5 Gopinathan, Unni; Øvstebø, Reidun; Brusletto, Berit Sletbakk; Olstad, Ole Kristoffer; Kierulf, Peter; Brandtzæg, Petter; Berg, Jens Petter.
Transcriptomic data from two primary cell models stimulating human monocytes suggest inhibition of oxidative phosphorylation and mitochondrial function by N. meningitidis which is partially up-regulated by IL-10. BMC Immunology 2017 ;Volum 18:46. s. 1-17
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6 Hellerud, Bernt C; Orrem, Hilde Lang; Dybwik, Knut Gustav; Pischke, Søren Erik; Barratt-Due, Andreas; Castellheim, Albert; Fure, Hilde; Bergseth, Grete; Christiansen, Dorte; Nunn, Miles A.; Espevik, Terje; Lau, Corinna; Brandtzæg, Petter; Nielsen, Erik Waage; Mollnes, Tom Eirik.
Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis. Journal of Intensive Care 2017 ;Volum 5:21. s. 1-9
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7 Hellum, Marit Synnøve; Siebke, Anne-Marie; Berg, Jens Petter; Brandtzæg, Petter; Øvstebø, Reidun; Henriksson, Carola.
The Neisseria meningitidis lpxL1 mutant induces less tissue factor expression and activity in primary human monocytes and monocyte-derived microvesicles than the wild type meningococcus. Innate Immunity 2017 ;Volum 23.(2) s. 196-205
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8 Knudsen, Per Kristian; Brandtzæg, Petter; Høiby, Ernst Arne; Bohlin, Jon; Samuelsen, Ørjan; Steinbakk, Martin; Abrahamsen, Tore G; Müller, Fredrik; Gammelsrud, Karianne Wiger.
Impact of extensive antibiotic treatment on faecal carriage of antibiotic-resistant enterobacteria in children in a low resistance prevalence setting. PLOS ONE 2017 ;Volum 12.(11) s. -
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2015
9 Gopinathan, Unni; Brusletto, Berit Sletbakk; Olstad, Ole Kristoffer; Kierulf, Peter; Berg, Jens Petter; Brandtzæg, Petter; Øvstebø, Reidun.
IL-10 immunodepletion from meningococcal sepsis plasma induces extensive changes in gene expression and cytokine release in stimulated human monocytes. Innate Immunity 2015 ;Volum 21.(4) s. 429-449
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10 Hellerud, Bernt C; Olstad, Ole Kristoffer; Nielsen, Erik W.; Siebke, Anne-Marie; Skadberg, Øyvind; Thorgersen, Ebbe Billmann; Vege, Åshild; Mollnes, Tom Eirik; Brandtzæg, Petter.
Massive organ inflammation in experimental and in clinical meningococcal septic shock. Shock 2015 ;Volum 44.(5) s. 458-469
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2014
11 Hellum, Marit Synnøve; Øvstebø, Reidun; Brusletto, Berit Sletbakk; Berg, Jens Petter; Brandtzæg, Petter; Henriksson, Carola.
Microparticle-associated tissue factor activity correlates with plasma levels of bacterial lipopolysaccharides in meningocoocal septic shock. Thrombosis Research 2014 ;Volum 133.(3) s. 507-514
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12 Øvstebø, Reidun; Hellum, Marit Synnøve; Aass, Hans Christian; Siebke, Anne-Marie; Brandtzæg, Petter; Mollnes, Tom Eirik; Henriksson, Carola.
Microparticle-associated tissue factor activity is reduced by inhibition of the complement protein 5 in Neisseria meningitidis-exposed whole blood. Innate Immunity 2014 ;Volum 20.(5) s. 552-560
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2013
13 Tønjum, Tone; Brandtzæg, Petter; Henriques-Normark, B.
Meningitis. I: The prokaryotes - Human Microbiology. Springer 2013 ISBN 978-3642301452. s. 401-427
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2012
14 Gammelsrud, Karianne Wiger; Langnes, Belinda; Gaustad, Peter; Ingebretsen, André; Høiby, Ernst Arne; Brandtzaeg, Petter; Sandven, Per.
Multilocus sequence typing of serial Candida albicans isolates from children with cancer, children with cystic fibrosis and healthy controls. Medical Mycology 2012 ;Volum 50.(6) s. 619-626
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15 Gopinathan, Unni; Øvstebø, Reidun; Olstad, Ole Kristoffer; Brusletto, Berit Sletbakk; Aass, Hans Christian; Kierulf, Peter; Brandtzæg, Petter; Berg, Jens Petter.
Global Effect of Interleukin-10 on the Transcriptional Profile Induced by Neisseria meningitidis in Human Monocytes. Infection and Immunity 2012 ;Volum 80.(11) s. 4046-4054
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16 Hellum, Marit Synnøve; Øvstebø, Reidun; Siebke, Anne-Marie; Berg, Jens Petter; Brandtzæg, Petter; Henriksson, Carola.
Microparticle-associated tissue factor activity measured with the Zymuphen MP-TF kit and the calibrated automated thrombogram assay. Blood Coagulation and Fibrinolysis 2012 ;Volum 23.(6) s. 520-526
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17 Kvakkestad, Kristin Marie; Gammelsrud, Karianne Wiger; Brandtzæg, Petter; Høiby, Ernst Arne.
Unchanged Antibiotic Susceptibility in Escherichia coli and Pseudomonas aeruginosa after Long-Term in vitro Exposure to Antineoplastic Drugs. Chemotherapy 2012 ;Volum 58.(2) s. 118-122
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18 Øvstebø, Reidun; Aass, Hans Christian; Foss, Kari Bente; Siebke, Anne-Marie; Gopinathan, Unni; Kierulf, Peter; Berg, Jens Petter; Brandtzæg, Petter; Henriksson, Carola.
LPS from Neisseria meningitidis is crucial for inducing monocyte- and microparticle-associated tissue factor activity but not for tissue factor expression. Innate Immunity 2012 ;Volum 18.(4) s. 580-591
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2011
19 Brandtzæg, Petter; van Deuren, Marcel.
Classification and pathogenesis of meningococcal disease. I: Neisseria meningitidis: Advances Methods and Protocols (Methods in Molecular Biology). Humana Press 2011 ISBN 1617793450. s. 21-35
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20 Brekke, Ole Lars; Hellerud, Bernt C; Christiansen, Dorte; Fure, Hilde; Castellheim, Albert; Nielsen, Erik Waage; Pharo, Anne Margrethe; Lindstad, Julie Katrine; Bergseth, Grete; Leslie, G; Lambris, John D.; Brandtzæg, Petter; Mollnes, Tom Eirik.
Neisseria meningitidis and Escherichia coli are protected from leukocyte phagocytosis by binding to erythrocyte complement receptor 1 in human blood. Molecular Immunology 2011 ;Volum 48.(15-16) s. 2159-2169
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21 Gammelsrud, Karianne Wiger; Sandven, Per; Høiby, Ernst Arne; Sandvik, Leiv; Brandtzæg, Petter; Gaustad, Peter.
Colonization by Candida in children with cancer, children with cystic fibrosis, and healthy controls. Clinical Microbiology and Infection 2011 ;Volum 17.(12) s. 1875-1881
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22 Hellerud, Bernt C; Aase, Audun; Næss, Lisbeth Meyer; Nome, Lisa; Herstad, Tove Karin; Lappegaard, Knut Tore; Skogen, Vegard; Brandtzæg, Petter; Høiby, Ernst Arne; Mollnes, Tom Eirik.
Vaccination of a C5-deficient man against Neisseria meningitidis: Effect on opsonophagocytosis and bacterial growth. Molecular Immunology 2011 ;Volum 48.(14) s. 1711-1711
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23 Hellerud, Bernt C.
Meningococcal sepsis : beneficial and harmful inflammatory mechanisms. Unipub forlag 2011 (ISBN 978-82-8264-141-8) Series of dissertations submitted to the Faculty of Medicine, University of Oslo(1142)
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24 Rasmussen, Inge; Wallace, Sean Ciaran; Mengshoel, Anne Torunn; Høiby, Ernst Arne; Brandtzæg, Petter.
Diphtheria outbreak in Norway: Lessons learned. Scandinavian Journal of Infectious Diseases 2011 ;Volum 43.(11-12) s. 986-989
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2010
25 Hellerud, Bernt C; Nielsen, Erik Waage; Thorgersen, Ebbe Billmann; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Tønnessen, Tor Inge; Castellheim, Albert; Mollnes, Tom Eirik; Brandtzæg, Petter.
Dissecting the effects of lipopolysaccharides from nonlipopolysaccharide molecules in experimental porcine meningococcal sepsis. Critical Care Medicine 2010 ;Volum 38.(6) s. 1467-1474
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26 Hellerud, Bernt Christian; Aase, Audun; Herstad, Tove Karin; Næss, Lisbeth Meyer; Kristiansen, Lisa Høyem; Siebke, Anne-Marie; Harboe, Morten; Lappegård, Knut Tore; Brandtzæg, Petter; Høiby, Ernst Arne; Mollnes, Tom Eirik.
Critical roles of complement and antibodies in host defense mechanisms against Neisseria meningitidis as revealed by human complement genetic deficiencies. Infection and Immunity 2010 ;Volum 78.(2) s. 802-809
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27 Krogh, Kristin; Surén, Pål; Mengshoel, Anne T; Brandtzæg, Petter.
Tuberculosis among children in Oslo, Norway, from 1998 to 2009. Scandinavian Journal of Infectious Diseases 2010 ;Volum 42.(11-12) s. 866-872
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2009
28 Gopinathan, U; Ovstebo, R; Olstad, OK; Kierulf, Peter; Brandtzæg, Petter; Berg, Jens Petter.
Interleukin-10 inhibits expression of genes induced by wild-type Neisseria meningitidis in human monocytes. Cytokine 2009 ;Volum 48.(1-2) s. 114-114
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29 Hellerud, Bernt C; Olstad, Ole Kristoffer; Brandtzæg, Petter; Mollnes, Tom Eirik.
Transcription of key components of complement and the TLR-signaling system is down-regulated by LPS in a porcine model of meningococcal sepsis. Molecular Immunology 2009 ;Volum 46.(14) s. 2853-2854
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30 Kristiansen, bjØrn-erik; Brandtzæg, Petter; Bjorvatn, Bjarne; Bjorvatn, Bjarne; Solberg, Claus Ola.
Meningokokkvaksineforsøket 1988-91. Tidsskrift for Den norske legeforening 2009 ;Volum 129.(3) s. 192-194
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31 Nielsen, Erik Waage; Hellerud, BC; Thorgersen, Ebbe B; Castellheim, A; Pharo, A; Lindstad, Julie; Tonnessen, Tor Inge; Tønnessen, Tor Inge; Brandtzæg, Petter; Mollnes, Tom Eirik.
A NEW DYNAMIC PORCINE MODEL OF MENINGOCOCCAL SHOCK. Shock 2009 ;Volum 32.(3) s. 302-309
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32 Ovstebo, R; Haug, KBF; Henriksson, C; Aass, HCD; Troseid, AMS; Olstad, OK; Kierulf, Peter; Brandtzæg, Petter; Berg, Jens Petter.
MicroRNA patterns in human monocytes induced by wildtype versus LPS deficient neisseria meningitides-Relationship between microRNA and LPS sensitive genes. Cytokine 2009 ;Volum 48.(1-2) s. 114-114
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2008
33 Hellerud, BC; Stenvik, Jørgen; Espevik, Terje; Lambris, JD; Mollnes, TE; Brandtzæg, Petter.
Stages of meningococcal sepsis simulated in vitro, with emphasis on complement and Toll-like receptor activation. Infection and Immunity 2008 ;Volum 76.(9) s. 4183-4189
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34 Hellerud, BC; Stenvik, Jørgen; Espevik, Terje; Lambris, John D.; Mollnes, Tom Eirik; Brandtzaeg, P.
Stages of meningococcal sepsis stimulated in vitro, with emphasis on complement and Toll-like receptor activation. Infection and Immunity 2008 ;Volum 76.(9) s. 4183-4189
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35 Rojahn, Astrid; Brusletto, Berit Sletbakk; Øvstebø, Reidun; Foss, Kari Bente; Kierulf, Peter; Brandtzæg, Petter.
Does granulocyte colony-stimulating factor ameliorate the proinflammatory response in human meningococcal septic shock?. Critical Care Medicine 2008 ;Volum 36. s. 2583-2589
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36 Øvstebø, Reidun; Olstad, Ole Kristoffer; Brusletto, Berit; Møller, Anne Sophie; Aase, Audun; Haug, Kari Bente Foss; Brandtzæg, Petter; Kierulf, Peter.
Identification of genes particularly sensitive to lipopolysaccharide (LPS) in human monocytes induced by wild-type versus LPS-Deficient Neisseria meningitidis strains. Infection and Immunity 2008 ;Volum 76.(6) s. 2685-2695
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2007
37 Hellerud, Bernt C; Thorgersen, Ebbe Billmann; Castellheim, Albert; Nielsen, EW; Pharo, Anne Margrethe; Lindstad, Julie Katrine; Fosse, Erik; Tønnessen, Tor Inge; Brandtzaeg, P; Mollnes, Tom Eirik.
The role of complement and CD14 in the Gram-negative bacteria induced inflammatory reaction: In vitro evidence and design of an in vivo porcine model. Molecular Immunology 2007 ;Volum 44. s. 182-182
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38 Hellerud, Bernt Christian; Høiby, Ernst Arne; Lappegård, Knut Tore; Fure, Hilde; Brandtzæg, Petter; Harboe, Morten; Mollnes, Tom Eirik.
Human genetic complement deficiencies reveal a critical role for C5/C5a in the phagocytosis and killing of Neisseria meningitidis and Escherichia coli in whole blood. Molecular Immunology 2007 ;Volum 44.(16) s. 3978-
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39 Stephens, DS; Greenwood, B; Brandtzæg, Petter.
Epidemic meningitis, meningococcaemia, and Neisseria meningitidis. The Lancet 2007 ;Volum 369.
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2005
40 Brandtzæg, Petter.
Recently discovered virus--known symptoms. Tidsskrift for Den norske legeforening 2005 ;Volum 125.(20)
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41 Møller, A; Bjerre, Anna; Brusletto, B; Joø, G. B.; Brandtzæg, Petter; Kierulf, Peter.
Chemokine patterns in meningococcal disease. Journal of Infectious Diseases 2005 ;Volum 191. s. 768-775
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42 Møller, Anne-Sophie Wiborg; Bjerre, Anna Kristina; Brusletto, Berit Sletbakk; Joø, Gun Brit; Brandtzæg, Petter; Kierulf, Peter.
Chemokine Pattern in Meningococcal Disease. Journal of Infectious Diseases 2005 ;Volum 191.(5) s. 768-775
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43 van Deuren, M; Brandtzæg, Petter.
Myocardial dysfunction in meningococcal septic shock: No clear answer yet. Critical Care Medicine 2005 ;Volum 33.
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2004
44 Brandtzæg, Petter.
Aktivert protein C ved sepsis (Editorial). Tidsskrift for Den norske legeforening 2004 ;Volum 124. s. 766-
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45 Sprong, T.; Møller, Anne-Sophie Wiborg; Bjerre, Anna Kristina; Wedege, E.; Kierulf, Peter; van der Meer, J. W. M.*; Brandtzæg, Petter; Van Deuren, Marcel; Mollnes, Tom Eirik.
Complement activation and complement-dependent inflammation by Neisseria meningitidis are independent of lipopolysaccharide. Infection and Immunity 2004 ;Volum 72.(6) s. 3344-3349
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46 Sprong, T; Møller, AS; Bjerre, A; Wedege, Elisabeth; Kierulf, P; van der Meer, JW; Brandtzæg, Petter; van Deuren, Marcel; Mollnes, TE.
Complement activation and complement-dependent inflammation by Neisseria meningitidis are independent of lipopolysaccharide. Infection and Immunity 2004 ;Volum 72. s. 3344-3349
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47 Øvstebø, Reidun; Brandtzæg, Petter; Brusletto, Berit Sletbakk; Foss, Kari Bente; Lande, Knut; Høiby, EA; Kierulf, Peter.
Use of robotized DNA isolation and real-time PCR to quantify and identify close correlation between levels of Neisseria meningitidis DNA and lipopolysaccharides in plasma and cerebrospinal fluid from patients with systemic meningococcal disease. Journal of Clinical Microbiology 2004 ;Volum 42. s. 2980-2987
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48 Bjerre, Anna Kristina; Brusletto, Berit Sletbakk; Høiby, Ernst Arne; Kierulf, Peter; Brandtzæg, Petter.
Plasma interferon-gamma and interleukin-10 concentrations in systemic meningococcal disease compared with severe systemic Gram-positive septic shock. Critical Care Medicine 2004 ;Volum 32. s. 433-438
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2003
49 Bjerre, Anna; Brusleto, Berit; Øvstebø, Reidun; Joø, Gun Britt; Kierulf, Peter; Brandtzæg, Petter.
Idenfication of meningococcal LPS as a major monocyte activator in IL-10 depleted shock plasmas and CSF by blocking the CD14-TLR4 receptor complex. Journal of Endotoxin Research 2003 ;Volum 9. s. 155-163
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50 Brandtzæg, Petter.
Meningococcal disease. I: Oxford Textbook of Medicine, 4th Edition. Oxford University Press 2003 s. 478-485
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