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2022
1 Aamdal, Elin; Skovlund, Eva; Jacobsen, Kari Dolven; Straume, Oddbjørn; Kersten, Christian; Herlofsen, Oluf; Karlsen, Jarle; Hussain, Israr; Amundsen, Anita; Dalhaug, Astrid; Nyakas, Marta Sølvi; Hagene, Kirsten Thorin; Holmsen, Kjersti; Aamdal, Steinar; Kaasa, Stein; Guren, Tormod Kyrre; Kyte, Jon A.
Health-related quality of life in patients with advanced melanoma treated with ipilimumab: prognostic implications and changes during treatment. ESMO Open 2022 ;Volum 7.(5) s. 1-10
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2 Ellingsen, Espen Basmo; Aamdal, Elin; Guren, Tormod Kyrre; Lilleby, Wolfgang; Brunsvig, Paal Fr.; Mangsbo, Sara M; Aamdal, Steinar; Hovig, Eivind; Mensali, Nadia; Gaudernack, Gustav; Inderberg, Else Marit.
Durable and dynamic hTERT immune responses following vaccination with the long-peptide cancer vaccine UV1: Long-Term follow-up of three phase i clinical trials. Journal for ImmunoTherapy of Cancer (JITC) 2022 ;Volum 10.(5) s. 1-13
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3 Lee, Che-Jui; Modave, Elodie; Boeckx, Bram; Kasper, Bernd; Aamdal, Steinar; Leahy, Michael G.; Rutkowski, Piotr; Bauer, Sebastian; Debiec-Rychter, Maria; Sciot, Raf; Lambrechts, Diether; Wozniak, Agnieszka; Schöffski, Patrick.
Correlation of Immunological and Molecular Profiles with Response to Crizotinib in Alveolar Soft Part Sarcoma: An Exploratory Study Related to the EORTC 90101 “CREATE” Trial. International Journal of Molecular Sciences 2022 ;Volum 23.(10) s. -
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2021
4 Aamdal, Elin; Inderberg, Else Marit; Ellingsen, Espen Basmo; Rasch, Wenche; Brunsvig, Paal Fr.; Aamdal, Steinar; Heintz, Karen Marie; Vodák, Daniel; Nakken, Sigve; Hovig, Eivind; Nyakas, Marta Sølvi; Guren, Tormod Kyrre; Gaudernack, Gustav.
Combining a universal telomerase based cancer vaccine with ipilimumab in patients with metastatic melanoma - Five-year follow up of a phase I/IIa trial. Frontiers in Immunology 2021 ;Volum 12. s. 1-10
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5 Aamdal, Elin; Jacobsen, Kari Dolven; Straume, Oddbjørn; Kersten, Christian; Herlofsen, Oluf; Karlsen, Jarle; Hussain, Israr; Amundsen, Anita; Dalhaug, Astrid; Nyakas, Marta Sølvi; Schuster, Cornelia; Hagene, Kirsten Thorin; Holmsen, Kjersti; Russnes, Hege Elisabeth Giercksky; Skovlund, Eva; Kaasa, Stein; Aamdal, Steinar; Kyte, Jon A.; Guren, Tormod Kyrre.
Ipilimumab in a real-world population: A prospective Phase IV trial with long-term follow-up. International Journal of Cancer 2021 ;Volum 150.(1) s. 100-111
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6 Tryggestad, Anne Merete Aaland; Axcrona, Karol; Axcrona, Ulrika; Bigalke, Iris; Brennhovd, Bjørn; Inderberg, Else Marit; Hønnåshagen, Turid Kirsti; Skoge, Lisbeth Johanne; Solum, Guri; Sæbøe-Larssen, Stein; Josefsen, Dag; Olaussen, Richard W.; Aamdal, Steinar; Myklebust, Tor Å.; Skotheim, Rolf I.; Schendel, Dolores J.; Lilleby, Wolfgang; Dueland, Svein; Kvalheim, Gunnar.
Long-term first-in-man Phase I/II study of an adjuvant dendritic cell vaccine in patients with high-risk prostate cancer after radical prostatectomy. The Prostate 2021 ;Volum 82.(2) s. 245-253
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2020
7 Brunsvig, Paal Fr.; Guren, Tormod Kyrre; Nyakas, Marta Sølvi; Reisse, Claudius; Rasch, Wenche; Kyte, Jon A; Juul, Hedvig Vidarsdotter; Aamdal, Steinar; Gaudernack, Gustav; Inderberg, Else Marit.
Long-term outcomes of a phase I study with UV1, a second generation telomerase based vaccine, in patients with advanced non-small cell lung cancer. Frontiers in Immunology 2020 ;Volum 11:572172. s. 1-12
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2019
8 Nyakas, Marta Sølvi; Aamdal, Elin; Jacobsen, Kari Dolven; Guren, Tormod Kyrre; Aamdal, Steinar; Hagene, Kirsten Thorin; Brunsvig, Paal Fr.; Yndestad, Arne; Halvorsen, Bente; Tasken, Kristin Austlid; Aukrust, Pål; Mælandsmo, Gunhild Mari; Ueland, Thor.
Prognostic biomarkers for immunotherapy with ipilimumab in metastatic melanoma. Clinical and Experimental Immunology 2019 ;Volum 197.(1) s. 74-82
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2018
9 Schöffski, Patrick; Wozniak, Agnieszka; Kasper, Bernd; Aamdal, Steinar; Leahy, Michael G.; Rutkowski, Piotr; Bauer, Sebastian; Gelderblom, Hans; Italiano, Antoine; Lindner, Lars H.; Hennig, I; Strauss, Sandra J.; Zakotnik, Branko; Anthoney, Alan; Albiges, Laurence; Blay, Jean-Yves; Reichardt, Peter; Sufliarsky, Jozef; van der Graaf, Winette; Debiec-Rychter, Maria; Sciot, Raf; Van Cann, Thomas; Marreaud, Sandrine; Raveloarivahy, Tiana; Collette, Sandra; Stacchiotti, Silvia.
Activity and safety of crizotinib in patients with alveolar soft part sarcoma with rearrangement of TFE3: European Organization for Research and Treatment of Cancer (EORTC) phase II trial 90101 ‘CREATE’. Annals of Oncology 2018 ;Volum 29.(3) s. 758-765
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10 Schöffski, Patrick; Wozniak, Agnieszka; Leahy, Michael G.; Aamdal, Steinar; Rutkowski, Piotr; Bauer, Sebastian; Richter, Stephan; Grünwald, Viktor; Debiec-Rychter, Maria; Sciot, Raf; Geoerger, Birgit; Marréaud, Sandrine; Collette, Sandra; Nzokirantevye, Axelle; Strauss, Sandra J..
The tyrosine kinase inhibitor crizotinib does not have clinically meaningful activity in heavily pre-treated patients with advanced alveolar rhabdomyosarcoma with FOXO rearrangement: European Organisation for Research and Treatment of Cancer phase 2 trial 90101 `CREATE?. European Journal of Cancer 2018 ;Volum 94. s. 156-167
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2017
11 Aamdal, Steinar; Bentzen, Heidi Beate; Borge, Ole Johan; Erikstein, Bjørn K; Grimsgaard, Sameline; Hovig, Johannes Eivind; Myklebost, Ola; Widerberg, Ketil.
Åpne Nordens grenser for forskning og behandling. Aftenposten (morgenutg. : trykt utg.) 2017
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12 Dueland, Svein; Guren, Tormod Kyrre; Boberg, Kirsten Muri; Reims, Henrik Mikael; Grzyb, Krzysztof; Aamdal, Steinar; Julsrud, Lars; Line, Pål Dag.
Acute liver graft rejection after ipilimumab therapy. Annals of Oncology 2017 ;Volum 28.(10) s. 2619-2620
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2016
13 Kyte, Jon A; Aamdal, Steinar; Dueland, Svein; Sæbøe-Larssen, Stein; Inderberg, Else Marit; Madsbu, Ulf Erik; Skovlund, Eva; Gaudernack, Gustav; Kvalheim, Gunnar.
Immune response and long-term clinical outcome in advanced melanoma patients vaccinated with tumor-mRNA-transfected dendritic cells. Oncoimmunology 2016 ;Volum 5.(11)
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14 Kyte, Jon A; Gaudernack, Gustav; Fåne, Anne; Lislerud, Kari; Inderberg, Else Marit; Brunsvig, Paal Fr.; Aamdal, Steinar; Kvalheim, Gunnar; Waelchli, Sebastien; Pulè, Martin.
T-helper cell receptors from long-term survivors after telomerase cancer vaccination for use in adoptive cell therapy. Oncoimmunology 2016 ;Volum 5:e1249090.(12)
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15 Sioud, Mouldy; Nyakas, Marta Sølvi; Sæbøe-Larssen, Stein; Mobergslien, Anne; Aamdal, Steinar; Kvalheim, Gunnar.
Diversification of Antitumour Immunity in a Patient with Metastatic Melanoma Treated with Ipilimumab and an IDO-Silenced Dendritic Cell Vaccine. Case Reports in Medicine 2016 ;Volum 2016.
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16 Straume, Oddbjørn; Geisler, Jürgen; Gullestad, Hans Petter; Nyakas, Marta Sølvi; Jacobsen, Kari Dolven; Aamdal, Steinar.
MEDIKAMENTELL KREFTBEHANDLING - Cytostatikaboken 8. utgave, Kapittel 34 - Malignt melanom. Oslo: Universitetet i Oslo, Det medisinske fakultet, Institutt for klinisk medisin, Avdeling for farmakologi 2016 (ISBN 978-82-992331-4-9) 661 s.
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2015
17 Andersson, Yvonne; Engebråten, Olav; Juell, Siri; Aamdal, Steinar; Brunsvig, Paal Fr.; Fodstad, Øystein; Dueland, Svein.
Phase I trial of EpCAM-targeting immunotoxin MOC31PE, alone and in combination with cyclosporin. British Journal of Cancer 2015 ;Volum 113.(11) s. 1548-1555
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18 Maio, Michele; Grob, Jean-Jacques; Aamdal, Steinar; Bondarenko, Igor; Robert, Caroline; Thomas, Luc; Garbe, Claus; Chiarion-Sileni, Vanna; Testori, Alessandro; Chen, Tai-Tsang; Tschaika, Marina; Wolchok, Jedd D..
Five-year survival rates for treatment-naive patients with advanced melanoma who received ipilimumab plus dacarbazine in a phase III trial. Journal of Clinical Oncology 2015 ;Volum 33.(10) s. 1191-1196
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19 Prasmickaite, Lina; Berge, Gisle; Bettum, Ingrid Johanne; Aamdal, Steinar; Hansson, Johan; Bastholt, Lars; Øijordsbakken, Miriam; Pedersen, Kjetil Boye; Mælandsmo, Gunhild.
Evaluation of serum osteopontin level and gene polymorphism as biomarkers: analyses from the Nordic Adjuvant Interferon alpha Melanoma trial. Cancer Immunology and Immunotherapy 2015 ;Volum 64.(6) s. 769-776
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20 Venugopal, Balaji; Awada, Ahmad; Evans, T.R. Jeffrey; Dueland, Svein; Hendlisz, Alain; Rasch, Wenche; Hernes, Kjell; Hagen, Steinar; Aamdal, Steinar.
A first-in-human phase i and pharmacokinetic study of CP-4126 (CO-101), a nucleoside analogue, in patients with advanced solid tumours. Cancer Chemotherapy and Pharmacology 2015 ;Volum 76.(4) s. 785-792
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2014
21 del Campo, Ana B.; Kyte, Jon A; Carretero, Javier; Zinchencko, Svitlana; Méndez, Rosa; González-Aseguinolaza, Gloria; Ruiz-Cabello, Francisco; Aamdal, Steinar; Gaudernack, Gustav; Garrido, Federico; Aptsiauri, Natalia.
Immune escape of cancer cells with beta2-microglobulin loss over the course of metastatic melanoma. International Journal of Cancer 2014 ;Volum 134.(1) s. 102-113
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22 Vihinen, Pia; Tervahartiala, Taina; Sorsa, Timo; Hansson, Johan; Bastholt, Lars; Aamdal, Steinar; Stierner, Ulrika; Pyrhönen, Seppo; Syrjänen, Kari; Lundin, Johan; Hernberg, Micaela.
Benefit of adjuvant interferon alfa-2b (IFN-α) therapy in melanoma patients with high serum MMP-8 levels. Cancer Immunology and Immunotherapy 2014 ;Volum 64.(2) s. 173-180
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2013
23 Brandberg, Yvonne; Johansson, Hemming; Aamdal, Steinar; Bastholt, Lars; Hernberg, Michaela; Stierner, Ulrika; von der Maase, Hans; Hansson, Johan.
Role functioning before start of adjuvant treatment was an independent prognostic factor for survival and time to failure. A report from the Nordic adjuvant interferon trial for patients with high-risk melanoma. Acta Oncologica 2013 ;Volum 52.(6) s. 1086-1093
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24 Cohen, Roger B.; Aamdal, Steinar; Nyakas, Marta Sølvi; Cavallin, Maria; Green, Darron; Learoyd, Maria; Smith, Ian; Kurzrock, Razelle.
A phase I dose-finding, safety and tolerability study of AZD8330 in patients with advanced malignancies. European Journal of Cancer 2013 ;Volum 49.(7) s. 1521-1529
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25 Geisler, Jürgen; Bachmann, Ingeborg M.; Nyakas, Marta Sølvi; Helsing, Per; Fjøsne, Hans E.; Mæhle, Lovise Olaug; Aamdal, Steinar; Eide, Nils; Svendsen, Henrik Løvendahl; Straume, Oddbjørn; Robsahm, Trude Eid; Dolven-Jacobsen, Kari; Akslen, Lars A..
Malignt melanom – diagnostikk, behandling og oppfølging i Norge. Tidsskrift for Den norske legeforening 2013 ;Volum 133.(20) s. 2154-2159
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26 Vik-Mo, Einar O.; Nyakas, Marta Sølvi; Lote, K.; Aamdal, Steinar; Gaudernack, Gustav; Langmoen, Iver Arne; Kvalheim, Gunnar.
CLINICAL EXPERIENCES WITH THERAPEUTIC DC VACCINES TARGETING AUTOLOGOUS CANCER STEM CELLS IN GLIOBLASTOMA. Cytotherapy 2013 ;Volum 15.(4) s. S14-S14
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27 Vik-Mo, Einar O.; Nyakas, Marta Sølvi; Mikkelsen, Birthe Viftrup; Moe, Morten Carsten; Due-Tønnessen, Paulina; Suso, Else Marit Inderberg; Sæbøe-Larssen, Stein; Sandberg, Cecilie; Brinchmann, Jan E.; Helseth, Eirik; Rasmussen, Anne Marie; Lothe, Knut; Aamdal, Steinar; Gaudernack, Gustav; Kvalheim, Gunnar; Langmoen, Iver Arne.
Therapeutic vaccination against autologous cancer stem cells with mRNA-transfected dendritic cells in patients with glioblastoma. Cancer Immunology and Immunotherapy 2013 ;Volum 62.(9) s. 1499-1509
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2012
28 Aamdal, Steinar.
The importance of patient selection in treatment efficacy. Annals of Oncology 2012 ;Volum 23.(supp. 9) s. 32-32
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29 Brandberg, Y.; Aamdal, Steinar; Bastholt, L.; Hernberg, M; Stierner, U.; von der Maase, H; Hansson, J..
Health-related quality of life in patients with high-risk melanoma randomised in the Nordic phase 3 trial with adjuvant intermediate-dose interferon alfa-2b. European Journal of Cancer 2012 ;Volum 48.(13) s. 2012-2019
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30 Kaye, S.; Aamdal, Steinar; Jones, R; Freyer, G; Pujade-Lauraine, Eric; de Vries, EGE; Barriuso, J; Sandhu, S; Tan, DS-W; Hartog, V; Kuenen, B; Ruijter, R; Kristensen, Gunnar S Balle; Nyakas, Marta Sølvi; Barrett, S; Burke, W; Pietersma, D; Stuart, M.; Emeribe, U; Boven, E.
Phase I study of saracatinib (AZD0530) in combination with paclitaxel and/or carboplatin in patients with solid tumours. British Journal of Cancer 2012 ;Volum 106.(11) s. 1728-1734
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2011
31 Aamdal, Steinar.
Current approaches to adjuvant therapy of melanoma. European Journal of Cancer 2011 ;Volum 47. Suppl. 3 s. S336-S337
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32 Brunsvig, Paal Fr.; Kyte, Jon A; Kersten, Christian; Sundstrøm, Stein Harald; Møller, Mona; Nyakas, Marta Sølvi; Hansen, Gaute Lund; Gaudernack, Gustav; Aamdal, Steinar.
Telomerase Peptide Vaccination in NSCLC: A Phase II Trial in Stage III Patients Vaccinated after Chemoradiotherapy and an 8-Year Update on a Phase I/II Trial. Clinical Cancer Research 2011 ;Volum 17.(21) s. 6847-6857
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33 Fox, Benard A.; Schendel, DJ; Butterfield, LH; Aamdal, Steinar; Allison, JP; Ascierto, PA; Atkins, MB; Bartunkova, J; Bergmann, L; Berinstein, N; Bonorino, CC; Borden, E; Bramson, JL; Britten, CM; Cao, XT; Carson, WE; Chang, AE; Characiejus, D; Choudhury, AR; Coukos, G.
Defining the critical hurdles in cancer immunotherapy. Journal of Translational Medicine 2011 ;Volum 9. s. -
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34 Hamid, Omid; schmidt, henrik; Nissan, Aviram; Ridolfi, Laura; Aamdal, Steinar; Hansson, Johan; Guida, Michele; Hyams, David; Gómez, Henry; Bastholt, Lars; Chasalow, Scott D.; Berman, David.
A prospective phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma. Journal of Translational Medicine 2011 ;Volum 9.(24)
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35 Hansson, Johan; Aamdal, Steinar; Bastholt, Lars; Brandberg, Yvonne; Hernberg, Micaela; Nilsson, Bo; Stierner, Ulrika; von der Maase, Hans.
Two different durations of adjuvant therapy with intermediate-dose interferon alfa-2b in patients with high-risk melanoma (Nordic IFN trial): a randomised phase 3 trial. The Lancet Oncology 2011 ;Volum 12.(2) s. 144-152
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36 Kyte, Jon A; Gaudernack, Gustav; Dueland, Svein; Trachsel, Sissel; Julsrud, Lars; Aamdal, Steinar.
Telomerase Peptide Vaccination Combined with Temozolomide: A Clinical Trial in Stage IV Melanoma Patients. Clinical Cancer Research 2011 ;Volum 17.(13) s. 4568-4580
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37 Suso, Else Marit Inderberg; Dueland, Svein; Rasmussen, Anne Marie; Vetrhus, Turid; Aamdal, Steinar; Kvalheim, Gunnar; Gaudernack, Gustav.
hTERT mRNA dendritic cell vaccination: complete response in a pancreatic cancer patient associated with response against several hTERT epitopes. Cancer Immunology and Immunotherapy 2011 ;Volum 60.(6) s. 809-818
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38 Zwierzina, Heinz; Bergmann, Lothar; Fiebig, Heiner; Aamdal, Steinar; Schöffski, Patrick; Witthohn, Klaus; Lentzen, Hans.
The preclinical and clinical activity of aviscumine: A potential anticancer drug. European Journal of Cancer 2011 ;Volum 47.(10) s. 1450-1457
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2010
39 Aamdal, Steinar; Boven, Epie; de Vries, Elisabeth G. E.; Pujade-Lauraine, Eric; Freyer, Gilles; Jones, R.; Prahladan, Manoj; Emeribe, Ugochi; Kaye, Steve.
PHASE I STUDY TO ASSESS THE SAFETY AND TOLERABILITY OF SARACATINIB (AZD0530) PLUS CARBOPLATIN (C) AND/OR PACLITAXEL (P) IN PATIENTS WITH SOLID TUMOURS. Annals of Oncology 2010 ;Volum 21. s. 171-172
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40 Edvardsen, Hege; Brunsvig, Paal Fr.; Solvang, Hiroko Kato; Tsalenko, A; Andersen, A; Syvanen, Ann-Christine; Yakhini, Z; Børresen-Dale, Anne-Lise; Olsen, H; Aamdal, Steinar; Kristensen, Vessela N..
SNPs in genes coding for ROS metabolism and signalling in association with docetaxel clearance. The Pharmacogenomics Journal 2010 ;Volum 10.(6) s. 513-523
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41 Han, L.; Aamdal, Steinar; Boven, Epie; Freyer, Gilles; Kristensen, Gunnar S Balle; Jones, R.; Pujade-Lauraine, Eric; de Vries, Elisabeth G. E.; Prahladan, M.; Kaye, Steve.
Treatment profile of saracatinib (AZD0530) in combination with chemotherapy in patients with advanced ovarian carcinoma. Gynecologic Oncology 2010 ;Volum 116.(3) s. S60-S60
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42 Prasmickaite, Lina; Skrbo, Nirma; Høifødt, Hanne Kleppe; Suo, Zhenhe; Engebråten, Olav; Gullestad, Hans petter; Aamdal, Steinar; Fodstad, Øystein; Mælandsmo, Gunhild M.
Human malignant melanoma harbours a large fraction of highly clonogenic cells that do not express markers associated with cancer stem cells. Pigment Cell & Melanoma Research 2010 ;Volum 23.(3) s. 449-451
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2009
43 Aamdal, Steinar; Wolchok, Jedd D.; Weber, Jeffrey S.; Hamid, Omid; O'Day, Steven J.; Schmidt, Henrik; Berman, David; Chasalow, Scott D..
Changes in peripheral blood absolute lymphocyte count (ALC) may guide patient selection for continued treatment with ipilimumab. European Journal of Cancer 2009 ;Volum 7.(2) s. 579-579
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44 Bouwhuis, Marna G.; Suciu, Stefan; Collette, Sandra; Aamdal, Steinar; Kruit, Wim H.; Bastholt, Lars; Stierner, Ulrika; Salès, Francois; Patel, Poulam; Punt, Cornelis J.A.; Hernberg, Micaela; Spatz, Alain; ten Hagen, Timo L.M.; Hansson, Johan; Eggermont, Alexander M.M..
Autoimmune Antibodies and Recurrence-Free Interval in Melanoma Patients Treated With Adjuvant Interferon. Journal of the National Cancer Institute 2009 ;Volum 101.(12) s. 869-877
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45 Dueland, Svein; Aamdal, Steinar; Lind, Mikael; Thomas, H; Sandvold, M. Liland; Gaullier, Jean-Michel; Rasch, Wenche.
Intravenous administration of CP-4055 (ELACYT (TM)) in patients with solid tumours. A phase I study. Acta Oncologica 2009 ;Volum 48.(1) s. 137-145
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46 Gunnes, Nina; Seierstad, Taral Guldahl; Aamdal, Steinar; Brunsvig, Paal Fr.; Jacobsen, Anne-Birgitte; Sundstrøm, Stein; Aalen, Odd O..
Assessing quality of life in a randomized clinical trial: Correcting for missing data. BMC Medical Research Methodology 2009 ;Volum 9.(28) s. -
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2008
47 Brunsvig, Paal Fredrik.
New diagnostic and therapeutic approaches in non-small cell lung cancer. Unipub forlag 2008 (ISBN 978-82-8072-475-5) 51 s.
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48 Brunsvig, Paal Fredrik; Flatmark, Kjersti; Aamdal, Steinar; Høifødt, Hanne Kleppe; Le, H; Jakobsen, E; Sandstad, Berit; Fodstad, Øystein.
Bone marrow micrometastases in advanced stage non-small cell lung carcinoma patients. Lung Cancer 2008 ;Volum 61.(2) s. 170-176
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49 Faye, Ragnar Solberg; Paus, E; Maelandsmo, GM; Berner, A; Hoifodt, HK; Fodstad, O; Aamdal, Steinar.
S100B in bone marrow aspirates in healthy individuals and malignant melanoma patients. Melanoma research 2008 ;Volum 18.(2) s. 134-140
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2007
50 Brunsvig, Paal Fr.; Andersen, Anders; Aamdal, Steinar; Kristensen, Vessela N.; Olsen, Harald.
Pharmacokinetic analysis of two different docetaxel dose levels in patients with non-small cell lung cancer treated with docetaxel as monotherapy or with concurrent radiotherapy. BMC Cancer 2007 ;Volum 7. s. 197-
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