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2023
1 Holme, Børge; Bjørnerud, Birgitte; Pedersen, Nina Marie; Rodriguez de la Ballina, Laura; Wesche, Jørgen; Haugsten, Ellen Margrethe.
Automated tracking of cell migration in phase contrast images with CellTraxx. Scientific Reports 2023 ;Volum 13.(1) s. -
HIOF SINTEF OUS UiO Untitled
 
2 Nakken, Sigve; Gundersen, Sveinung; Bernal, Fabian Leonardo Martinez; Polychronopoulos, Dimitris; Hovig, Eivind; Wesche, Jørgen.
Comprehensive interrogation of gene lists from genome-scale cancer screens with oncoEnrichR. International Journal of Cancer 2023 ;Volum 153.(10) s. 1819-1828
UiO OUS Untitled
 
2022
3 Fiorito, Elisa; Szybowska, Patrycja Maria; Haugsten, Ellen Margrethe; Kostas, Michal Janusz; Øy, Geir Frode; Wiedlocha, Antoni; Singh, Sachin Kumar; Nakken, Sigve; Mælandsmo, Gunhild Mari; Fletcher, Jonathan A.; Meza, Leonardo Zepeda; Wesche, Jørgen.
Strategies to inhibit FGFR4 V550L-driven rhabdomyosarcoma. British Journal of Cancer 2022 ;Volum 127. s. 1939-1953
OUS UiO UiT Untitled
 
4 Wesche, Jørgen.
Activation of FGFR1 by inorganic phosphate and oxidative stress. Molmed seminar; 2022-10-26
UiO Untitled
 
5 Wesche, Jørgen.
Jakten på molekylene som hjelper kreftceller å spre seg til nye steder i kroppen. Møt en forsker; 2022-11-18 - 2022-11-18
UiO Untitled
 
2021
6 Munson, Michael Joseph; Mathai, Benan J.; Ng, Matthew; Trachsel Moncho, Laura Cristina; de la Ballina, Laura R; Schultz, Sebastian W.; Aman, Yahyah; Lystad, Alf H.; Singh, Sakshi; Singh, Sachin; Wesche, Jørgen; Fang, Evandro F.; Simonsen, Anne.
GAK and PRKCD are positive regulators of PRKN-independent mitophagy. Nature Communications 2021 ;Volum 12.(1) s. -
UiO OUS AHUS Untitled
 
7 Szybowska, Patrycja Maria; Kostas, Michal Janusz; Wesche, Jørgen; Haugsten, Ellen Margrethe; Wiedlocha, Antoni.
Negative Regulation of FGFR (Fibroblast Growth Factor Receptor) Signaling. Cells 2021 ;Volum 10.(6) s. 1-18
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8 Vikan, Aurora; Haugsten, Ellen Margrethe; Kostas, Michal Janusz; Selbo, Pål Kristian; Wesche, Jørgen.
Efficacy and selectivity of fgf2-saporin cytosolically delivered by pci in cells overexpressing fgfr1. Cells 2021 ;Volum 10.(6) s. 1-16
OUS UiO Untitled
 
2020
9 Tadele, Dagim Shiferaw; Robertson, Joseph; Crispin, Richard; Herrera, Carmen; Chlubnová, Markéta; Piechaczyk, Laure Isabelle; Ayuda-Duran, Maria del Pilar; Singh, Sachin Kumar; Gedde-Dahl, Tobias; Fløisand, Yngvar; Skavland, Jørn; Wesche, Jørgen; Gjertsen, Bjørn Tore; Enserink, Jorrit.
A cell competition-based small molecule screen identifies a novel compound that induces dual c-Myc depletion and p53 activation. Journal of Biological Chemistry 2020 ;Volum 296. s. -
UiO OUS UiB Untitled
 
2019
10 Szybowska, Patrycja Maria; Kostas, Michal Janusz; Wesche, Jørgen; Wiedlocha, Antoni; Haugsten, Ellen Margrethe.
Cancer Mutations in FGFR2 Prevent a Negative Feedback Loop Mediated by the ERK1/2 Pathway. Cells 2019 ;Volum 8.(6) s. 1-18
OUS UiO Untitled
 
2018
11 Fafílek, Bohumil; Bálek, Lukáš; Bosakova, Michaela Kunova; Vařecha, Miroslav; Nita, Alexandru; Gregor, Tomas; Gudernovǎ, Iva; Krenova, Jitka; Ghosh, Somadri; Piskáček, Martin; Jonatova, Lucie; Cernohorsky, Nicole H.; Zieba, Jennifer T.; Kostas, Michal Janusz; Haugsten, Ellen Margrethe; Wesche, Jørgen; Erneux, Christophe; Trántirek, Lukáš; Krakow, Deborah; Krejčí, Pavel.
The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases. Science Signaling 2018 ;Volum 11:eaap8608.(548) s. 1-15
UiO OUS Untitled
 
12 Kostas, Michal Janusz; Haugsten, Ellen Margrethe; Zhen, Yan; Sørensen, Vigdis; Szybowska, Patrycja Maria; Fiorito, Elisa; Lorenz, Susanne; Jones, Nina; De Souza, Gustavo Antonio; Wiedlocha, Antoni; Wesche, Jørgen.
Protein Tyrosine Phosphatase Receptor Type G (PTPRG) controls Fibroblast Growth Factor Receptor (FGFR) 1 activity and influences sensitivity to FGFR kinase inhibitors. Molecular & Cellular Proteomics 2018 ;Volum 17.(5) s. 850-870
UiO OUS Untitled
 
13 Zhen, Yan; Haugsten, Ellen Margrethe; Singh, Sachin Kumar; Wesche, Jørgen.
Proximity Labeling by a Recombinant APEX2-FGF1 Fusion Protein Reveals Interaction of FGF1 with the Proteoglycans CD44 and CSPG4. Biochemistry 2018 ;Volum 57.(26) s. 3807-3816
OUS UiO Untitled
 
2016
14 Haugsten, Ellen Margrethe; Sørensen, Vigdis; Kunova Bosakova, Michaela; De Souza, Gustavo Antonio; Krejci, Pavel; Wiedlocha, Antoni; Wesche, Jørgen.
Proximity Labeling Reveals Molecular Determinants of FGFR4 Endosomal Transport. Journal of Proteome Research 2016 ;Volum 15.(10) s. 3841-3855
OUS UiO Untitled
 
2014
15 Haugsten, Ellen Margrethe; Brech, Andreas; Liestøl, Knut; Norman, Jim C.; Wesche, Jørgen.
Photoactivation Approaches Reveal a Role for Rab11 in FGFR4 Recycling and Signalling. Traffic: The moving front of cell biology 2014 ;Volum 15.(6) s. 665-683
OUS UiO Untitled
 
16 Nadratowska-Wesolowska, Beata; Haugsten, Ellen Margrethe; Zakrzewska, Malgorzata; Jakimowicz, Piotr; Zhen, Yan; Pajdzik, Dorota; Wesche, Jørgen; Wiedlocha, Antoni.
RSK2 regulates endocytosis of FGF receptor 1 by phosphorylation on serine 789. Oncogene 2014 ;Volum 33.(40) s. 4823-4836
UiO OUS Untitled
 
17 Oppelt, Angela; Haugsten, Ellen Margrethe; Zech, Tobias; Danielsen, Håvard Emil; Sveen, Anita; Lobert, Viola Helene; Skotheim, Rolf Inge; Wesche, Jørgen.
PIKfyve, MTMR3 and their product PtdIns5P regulate cancer cell migration and invasion through activation of Rac1. Biochemical Journal 2014 ;Volum 461.(3) s. 383-390
OUS UiO Untitled
 
2013
18 Haugsten, Ellen Margrethe; Oppelt, Angela; Wesche, Jørgen.
Phosphatidylinositol 5-phosphate is a second messenger important for cell migration. Communicative & Integrative Biology 2013 ;Volum 6.(5) s. -
OUS UiO Untitled
 
19 Oppelt, Angela; Lobert, Viola Helene; Haglund, Kaisa; Mackey, Ashley M.; Rameh, Lucia E.; Liestøl, Knut; Schink, Kay Oliver; Pedersen, Nina Marie; Wenzel, Eva; Haugsten, Ellen Margrethe; Brech, Andreas; Rusten, Tor Erik; Stenmark, Harald Alfred; Wesche, Jørgen.
Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration. EMBO Reports 2013 ;Volum 14.(1) s. 57-64
UiO OUS NTNU Untitled
 
20 Zakrzewska, Malgorzata; Haugsten, Ellen Margrethe; Nadratowska-Wesolowska, Beata; Oppelt, Angela; Hausott, Barbara; Jin, Yixin; Otlewski, Jacek; Wesche, Jørgen; Wiedlocha, Antoni.
ERK-Mediated Phosphorylation of Fibroblast Growth Factor Receptor 1 on Ser(777) Inhibits Signaling. Science Signaling 2013 ;Volum 6.(262) s. -
UiO OUS Untitled
 
2011
21 Haugsten, Ellen Margrethe; Zakrzewska, Malgorzata; Brech, Andreas; Pust, Sascha; Olsnes, Sjur; Sandvig, Kirsten; Wesche, Jørgen.
Clathrin- and Dynamin-Independent Endocytosis of FGFR3-Implications for Signalling. PLOS ONE 2011 ;Volum 6.(7) s. -
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22 Wesche, Jørgen; Haglund, Kaisa; Haugsten, Ellen Margrethe.
Fibroblast growth factors and their receptors in cancer. Biochemical Journal 2011 ;Volum 437. s. 199-213
UiO OUS Untitled
 
2010
23 Haglund, Kaisa; Nezis, Jonnis P; Lemus Torres, Dafne; Grabbe, C; Wesche, Jørgen; Liestøl, Knut; Dikic, I; Stenmark, Harald Alfred; Palmer, R. Barton.
Cindr Interacts with Anillin to Control Cytokinesis in Drosophila melanogaster. Current Biology 2010 ;Volum 20.(10) s. 944-950
UiO OUS Untitled
 
24 Haugsten, Ellen Margrethe; Wiedlocha, Antoni; Olsnes, Sjur; Wesche, Jørgen.
Roles of Fibroblast Growth Factor Receptors in Carcinogenesis. Molecular Cancer Research 2010 ;Volum 8.(11) s. 1439-1452
UiO OUS Untitled
 
25 Lobert, Viola Helene; Brech, Andreas; Pedersen, Nina Marie; Wesche, Jørgen; Oppelt, Angela; Malerød, Lene; Stenmark, Harald.
Ubiquitination of alpha 5 beta 1 lntegrin Controls Fibroblast Migration through Lysosomal Degradation of Fibronectin-lntegrin Complexes. Developmental Cell 2010 ;Volum 19.(1) s. 148-159
NTNU UiO OUS Untitled
 
2009
26 Zakrzewska, Malgorzata; Zhen, Yan; Wiedlocha, Antoni; Olsnes, Sjur; Wesche, Jørgen.
Size Limitation in Translocation of Fibroblast Growth Factor 1 Fusion Proteins across the Endosomal Membrane. Biochemistry 2009 ;Volum 48.(30) s. 7209-7218
UiO OUS Untitled
 
2008
27 Haugsten, Ellen Margrethe; Malecki, Jedrzej M.; Bjørklund, Sunniva Maria Stordal; Olsnes, Sjur; Wesche, Jørgen.
Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis. Molecular Biology of the Cell 2008 ;Volum 19. s. 3390-3403
UiO OUS Untitled
 
2007
28 Nilsen, Trine; Rosendal, Ken; Sørensen, Vigdis; Wesche, Jørgen; Olsnes, Sjur; Widocha, Antoni.
A nuclear export sequence located on a beta-strand in fibroblast growth factor-1. Journal of Biological Chemistry 2007 ;Volum 282.(36) s. 26245-26256
UiO Untitled
 
2006
29 Sørensen, Vigdis; Wiedlocha, Antoni; Haugsten, Ellen Margrethe; Khnykin, Denis; Wesche, Jørgen; Olsnes, Sjur.
Different abilities of the four FGFRs to mediate FGF-1 translocation are linked to differences in the receptor C-terminal tail. Journal of Cell Science 2006 ;Volum 119. s. 4332-4341
UiO Untitled
 
30 Wesche, Jørgen; Malecki, Jedrzej M.; Wiedlocha, Antoni; Skjerpen, Camilla Skiple; Claus, P; Olsnes, Sjur.
FGF-1 and FGF-2 require the cytosolic chaperone Hsp90 for translocation into the cytosol and the cell nucleus. Journal of Biological Chemistry 2006 ;Volum 281. s. 11405-11412
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2005
31 Haugsten, Ellen Margrethe; Sørensen, Vigdis; Olsnes, Sjur; Wesche, Jørgen; Brech, Andreas.
Different intracellular trafficking of FGF1 endocytosed by the four specific and homologous FGF receptors. Journal of Cell Science 2005 ;Volum 118. s. 3869-3881
UiO Untitled
 
32 Skjerpen, Camilla Skiple.
Translocation mechanism and cellular interaction partners of FGF-1 and FGF-2. Unipub forlag 2005 (ISBN 82-8072-158-4) 56 s.
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33 Wesche, Jørgen; Malecki, Jedrzej M.; Wiedlocha, Antoni; Ehsani, Maryam; Nilsen, Trine; Marcinkowska, Ewa; Olsnes, Sjur.
Two nuclear localization signals required for transport from the cytosol to the, nucleus of externally added FGF-1 translocated into cells. Biochemistry (Moscow) 2005 ;Volum 44.
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34 Wiedlocha, Antoni; Nilsen, Trine; Wesche, Jørgen; Sørensen, Vigdis; Malecki, M; Marcinkowska, Ewa; Olsnes, Sjur.
Phosphorylation-regulated nucleocytoplasmic trafficking of internalized fibroblast growth factor-1. Molecular Biology of the Cell 2005 (16) s. 794-810
UiO OUS Untitled
 
2004
35 Malecki, Jedrzej; Wesche, Jørgen; Skjerpen, Camilla Skiple; Wiedlocha, Antoni; Olsnes, Sjur.
Translocation of FGF-1 and FGF-2 across Vesicular Membranes Occurs during G1-Phase by a Common Mechanism. Molecular Biology of the Cell 2004 ;Volum 15. s. 804-814
UiO Untitled