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2019
1 Szybowska, Patrycja Maria; Kostas, Michal Janusz; Wesche, Jørgen; Wiedlocha, Antoni; Haugsten, Ellen Margrethe.
Cancer Mutations in FGFR2 Prevent a Negative Feedback Loop Mediated by the ERK1/2 Pathway. Cells 2019 ;Volum 8.(6) s. 1-18
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2018
2 Fafílek, Bohumil; Bálek, Lukáš; Bosakova, Michaela Kunova; Vařecha, Miroslav; Nita, Alexandru; Gregor, Tomas; Gudernovǎ, Iva; Krenova, Jitka; Ghosh, Somadri; Piskáček, Martin; Jonatova, Lucie; Cernohorsky, Nicole H.; Zieba, Jennifer T.; Kostas, Michal Janusz; Haugsten, Ellen Margrethe; Wesche, Jørgen; Erneux, Christophe; Trántirek, Lukáš; Krakow, Deborah; Krejčí, Pavel.
The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases. Science Signaling 2018 ;Volum 11:eaap8608.(548) s. 1-15
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3 Kostas, Michal Janusz; Haugsten, Ellen Margrethe; Zhen, Yan; Sørensen, Vigdis; Szybowska, Patrycja Maria; Fiorito, Elisa; Lorenz, Susanne; Jones, Nina; De Souza, Gustavo Antonio; Wiedlocha, Antoni; Wesche, Jørgen.
Protein Tyrosine Phosphatase Receptor Type G (PTPRG) controls Fibroblast Growth Factor Receptor (FGFR) 1 activity and influences sensitivity to FGFR kinase inhibitors. Molecular & Cellular Proteomics 2018 ;Volum 17.(5) s. 850-870
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4 Zhen, Yan; Haugsten, Ellen Margrethe; Singh, Sachin Kumar; Wesche, Jørgen.
Proximity Labeling by a Recombinant APEX2-FGF1 Fusion Protein Reveals Interaction of FGF1 with the Proteoglycans CD44 and CSPG4. Biochemistry 2018 ;Volum 57.(26) s. 3807-3816
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2016
5 Haugsten, Ellen Margrethe; Sørensen, Vigdis; Kunova Bosakova, Michaela; De Souza, Gustavo Antonio; Krejci, Pavel; Wiedlocha, Antoni; Wesche, Jørgen.
Proximity Labeling Reveals Molecular Determinants of FGFR4 Endosomal Transport. Journal of Proteome Research 2016 ;Volum 15.(10) s. 3841-3855
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2014
6 Haugsten, Ellen Margrethe; Brech, Andreas; Liestøl, Knut; Norman, Jim C.; Wesche, Jørgen.
Photoactivation Approaches Reveal a Role for Rab11 in FGFR4 Recycling and Signalling. Traffic : the International Journal of Intracellular Transport 2014 ;Volum 15.(6) s. 665-683
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7 Nadratowska-Wesolowska, Beata; Haugsten, Ellen Margrethe; Zakrzewska, Malgorzata; Jakimowicz, Piotr; Zhen, Yan; Pajdzik, Dorota; Wesche, Jørgen; Wiedlocha, Antoni.
RSK2 regulates endocytosis of FGF receptor 1 by phosphorylation on serine 789. Oncogene 2014 ;Volum 33.(40) s. 4823-4836
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8 Oppelt, Angela; Haugsten, Ellen Margrethe; Zech, Tobias; Danielsen, Håvard Emil; Sveen, Anita; Lobert, Viola Helene; Skotheim, Rolf Inge; Wesche, Jørgen.
PIKfyve, MTMR3 and their product PtdIns5P regulate cancer cell migration and invasion through activation of Rac1. Biochemical Journal 2014 ;Volum 461.(3) s. 383-390
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2013
9 Oppelt, Angela; Lobert, Viola Helene; Haglund, Kaisa; Mackey, Ashley M.; Rameh, Lucia E.; Liestøl, Knut; Schink, Kay Oliver; Pedersen, Nina Marie; Wenzel, Eva; Haugsten, Ellen Margrethe; Brech, Andreas; Rusten, Tor Erik; Stenmark, Harald Alfred; Wesche, Jørgen.
Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration. EMBO Reports 2013 ;Volum 14.(1) s. 57-64
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10 Zakrzewska, Malgorzata; Haugsten, Ellen Margrethe; Nadratowska-Wesolowska, Beata; Oppelt, Angela; Hausott, Barbara; Jin, Yixin; Otlewski, Jacek; Wesche, Jørgen; Wiedlocha, Antoni.
ERK-Mediated Phosphorylation of Fibroblast Growth Factor Receptor 1 on Ser(777) Inhibits Signaling. Science Signaling 2013 ;Volum 6.(262) s. -
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2011
11 Haugsten, Ellen Margrethe; Zakrzewska, Malgorzata; Brech, Andreas; Pust, Sascha; Olsnes, Sjur; Sandvig, Kirsten; Wesche, Jørgen.
Clathrin- and Dynamin-Independent Endocytosis of FGFR3-Implications for Signalling. PLOS ONE 2011 ;Volum 6.(7) s. -
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12 Wesche, Jørgen; Haglund, Kaisa; Haugsten, Ellen Margrethe.
Fibroblast growth factors and their receptors in cancer. Biochemical Journal 2011 ;Volum 437. s. 199-213
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2010
13 Haglund, Kaisa; Nezis, Jonnis P; Lemus Torres, Dafne; Grabbe, C; Wesche, Jørgen; Liestøl, Knut; Dikic, I; Stenmark, Harald Alfred; Palmer, R. Barton.
Cindr Interacts with Anillin to Control Cytokinesis in Drosophila melanogaster. Current Biology 2010 ;Volum 20.(10) s. 944-950
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14 Haugsten, Ellen Margrethe; Wiedlocha, Antoni; Olsnes, Sjur; Wesche, Jørgen.
Roles of Fibroblast Growth Factor Receptors in Carcinogenesis. Molecular Cancer Research 2010 ;Volum 8.(11) s. 1439-1452
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15 Lobert, Viola Helene; Brech, Andreas; Pedersen, Nina Marie; Wesche, Jørgen; Oppelt, Angela; Malerød, Lene; Stenmark, Harald.
Ubiquitination of alpha 5 beta 1 lntegrin Controls Fibroblast Migration through Lysosomal Degradation of Fibronectin-lntegrin Complexes. Developmental Cell 2010 ;Volum 19.(1) s. 148-159
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2009
16 Zakrzewska, Malgorzata; Zhen, Yan; Wiedlocha, Antoni; Olsnes, Sjur; Wesche, Jørgen.
Size Limitation in Translocation of Fibroblast Growth Factor 1 Fusion Proteins across the Endosomal Membrane. Biochemistry 2009 ;Volum 48.(30) s. 7209-7218
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2008
17 Haugsten, Ellen Margrethe; Malecki, Jedrzej M.; Bjørklund, Sunniva Maria Stordal; Olsnes, Sjur; Wesche, Jørgen.
Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis. Molecular Biology of the Cell 2008 ;Volum 19. s. 3390-3403
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2007
18 Nilsen, Trine; Rosendal, Ken; Sørensen, Vigdis; Wesche, Jørgen; Olsnes, Sjur; Widocha, Antoni.
A nuclear export sequence located on a beta-strand in fibroblast growth factor-1. Journal of Biological Chemistry 2007 ;Volum 282.(36) s. 26245-26256
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2006
19 Sørensen, Vigdis; Wiedlocha, Antoni; Haugsten, Ellen Margrethe; Khnykin, Denis; Wesche, Jørgen; Olsnes, Sjur.
Different abilities of the four FGFRs to mediate FGF-1 translocation are linked to differences in the receptor C-terminal tail. Journal of Cell Science 2006 ;Volum 119. s. 4332-4341
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20 Wesche, Jørgen; Malecki, Jedrzej M.; Wiedlocha, Antoni; Skjerpen, Camilla Skiple; Claus, P; Olsnes, Sjur.
FGF-1 and FGF-2 require the cytosolic chaperone Hsp90 for translocation into the cytosol and the cell nucleus. Journal of Biological Chemistry 2006 ;Volum 281. s. 11405-11412
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2005
21 Haugsten, Ellen Margrethe; Sørensen, Vigdis; Olsnes, Sjur; Wesche, Jørgen; Brech, Andreas.
Different intracellular trafficking of FGF1 endocytosed by the four specific and homologous FGF receptors. Journal of Cell Science 2005 ;Volum 118. s. 3869-3881
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22 Skjerpen, Camilla Skiple.
Translocation mechanism and cellular interaction partners of FGF-1 and FGF-2. Unipub forlag 2005 (ISBN 82-8072-158-4) 56 s.
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23 Wesche, Jørgen; Malecki, Jedrzej M.; Wiedlocha, Antoni; Ehsani, Maryam; Nilsen, Trine; Marcinkowska, Ewa; Olsnes, Sjur.
Two nuclear localization signals required for transport from the cytosol to the, nucleus of externally added FGF-1 translocated into cells. Biochemistry (Moscow) 2005 ;Volum 44.
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24 Wiedlocha, Antoni; Nilsen, Trine; Wesche, Jørgen; Sørensen, Vigdis; Malecki, M; Marcinkowska, Ewa; Olsnes, Sjur.
Phosphorylation-regulated nucleocytoplasmic trafficking of internalized fibroblast growth factor-1. Molecular Biology of the Cell 2005 (16) s. 794-810
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2004
25 Malecki, Jedrzej; Wesche, Jørgen; Skjerpen, Camilla Skiple; Wiedlocha, Antoni; Olsnes, Sjur.
Translocation of FGF-1 and FGF-2 across Vesicular Membranes Occurs during G1-Phase by a Common Mechanism. Molecular Biology of the Cell 2004 ;Volum 15. s. 804-814
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