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2020
1 Samuelsen, Ørjan; Åstrand, Ove Alexander Høgmoen; Frøhlich, Christopher; Heikal, Adam; Skagseth, Susann; Carlsen, Trine Josefine Olsen; Leiros, Hanna-Kirsti S.; Bayer, Annette; Schnaars, Christian; Kildahl-andersen, Geir; Lauksund, Silje; Finke, Sarah; Huber, Sandra; Gjøen, Tor; Andresen, Adriana Magalhaes Santos; Økstad, Ole Andreas; Rongved, Pål.
ZN148 Is a Modular Synthetic Metallo-beta-Lactamase Inhibitor That Reverses Carbapenem Resistance in Gram-Negative Pathogens In Vivo. Antimicrobial Agents and Chemotherapy 2020
UiO UiT Untitled
 
2019
2 Issa, Samar; Prandina, Anthony; Bedel, Nicolas; Rongved, Pål; Yous, Saïd; Le Borgne, Marc; Bouaziz, Zouhair.
Carbazole scaffolds in cancer therapy: a review from 2012 to 2018. Journal of enzyme inhibition and medicinal chemistry (Print) 2019 ;Volum 34.(1) s. 1321-1346
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3 Kildahl-Andersen, Geir; Schnaars, Christian; Prandina, Anthony; Radix, Sylvie; Le Borgne, Marc; Jordheim, Lars Petter; Gjøen, Tor; Andresen, Adriana Magalhaes Santos; Lauksund, Silje; Fröhlich, Christopher; Samuelsen, Ørjan; Rongved, Pål; Åstrand, Ove Alexander Høgmoen.
Synthesis and biological evaluation of zinc chelating compounds as metallo-β-lactamase inhibitors. MedChemComm 2019 ;Volum 10.(4) s. 528-537
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4 Olsen, Christine; Skottvoll, Frøydis Sved; Brandtzaeg, Ole Kristian; Schnaars, Christian; Rongved, Pål; Lundanes, Elsa; Wilson, Steven Ray Haakon.
Investigating Monoliths (Vinyl Azlactone-co-Ethylene Dimethacrylate) as a Support for Enzymes and Drugs, for Proteomics and Drug-Target Studies. Frontiers in Chemistry 2019 ;Volum 7. s. -
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5 Olsen, Christine.
Synthesis and immobilization of linked Wnt-signaling pathway inhibitor on organic monoliths as a proof-of-concept of a capti remedium ad monolitus reactor for online drug deconvolution. Oslo: Universitetet i Oslo 2019 142 s.
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6 Peeters, Sara; Berntsen, Linn Neerbye; Rongved, Pål; Bonge-Hansen, Tore.
Cyclopropanation–ring expansion of 3-chloroindoles with α-halodiazoacetates: novel synthesis of 4-quinolone-3-carboxylic acid and norfloxacin. Beilstein Journal of Organic Chemistry 2019 ;Volum 15. s. 2156-2160
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7 Prandina, Anthony; Radix, Sylvie; Le Borgne, Marc; Jordheim, Lars Petter; Bousfiha, Zineb; Fröhlich, Christopher; Leiros, Hanna-Kirsti S.; Samuelsen, Ørjan; Frøvold, Espen; Rongved, Pål; Åstrand, Ove Alexander Høgmoen.
Synthesis and biological evaluation of new dipicolylamine zinc chelators as metallo-β-lactamase inhibitors. Tetrahedron 2019 ;Volum 75.(11) s. 1525-1540
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2018
8 Berntsen, Linn Neerbye.
Rh(II)-catalyzed cyclopropanation-ring expansion of 7-azaindoles with halodiazoacetates and indoles with halodiazophosphonates. Oslo: Kjemisk Institutt, Universitetet i Oslo 2018 214 s.
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9 Prandina, Anthony; Herfindal, Lars; Radix, Sylvie; Rongved, Pål; Doskeland, Stein Ove; Le Borgne, Marc; Perret, Florent.
Enhancement of iodinin solubility by encapsulation into cyclodextrin nanoparticles. Journal of enzyme inhibition and medicinal chemistry (Print) 2018 ;Volum 33.(1) s. 370-375
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10 Schnaars, Christian; kildahl-Andersen, Geir; Prandina, Anthony; Popal, Roya; Radix, Sylvie; Le Borgne, Marc; Gjøen, Tor; Andresen, Adriana Magalhaes Santos; Heikal, Adam; Økstad, Ole Andreas Løchen; Fröhlich, Christopher; Samuelsen, Ørjan; Lauksund, Silje; Jordheim, Lars Petter; Rongved, Pål; Åstrand, Ove Alexander Høgmoen.
Synthesis and preclinical evaluation of TPA-based zinc chelators as metallo-β-lactamase inhibitors. ACS Infectious Diseases 2018 ;Volum 4.(9) s. 1407-1422
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2017
11 Viktorsson, Elvar Örn; Gabrielsen, Mari; Kumarachandran, Nugalya; Sylte, Ingebrigt; Rongved, Pål; Åstrand, Ove Alexander Høgmoen; Kase, Eili Tranheim.
Regulation of liver X receptor target genes by 22-functionalized oxysterols. Synthesis, in silico and in vitro evaluations. Steroids 2017 ;Volum 118. s. 119-127
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12 Viktorsson, Elvar Örn; Grøthe, Bendik Melling; Aesoy, Reidun; Sabir, Misbah; Snellingen, Simen; Åstrand, Ove Alexander Høgmoen; Prandina, Anthony; Bonge-Hansen, Tore; Doskeland, Stein Ove; Herfindal, Lars; Rongved, Pål.
Total synthesis and antileukemic evaluations of the phenazine 5,10-dioxide natural products iodinin, myxin and their derivatives. Bioorganic & Medicinal Chemistry 2017 ;Volum 25.(7) s. 2285-2293
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13 Åstrand, Ove Alexander Høgmoen; Viktorsson, Elvar Örn; Kristensen, Aleksander Lim; Ekeberg, Dag; Røberg-Larsen, Hanne; Wilson, Steven Ray Haakon; Gabrielsen, Mari; Sylte, Ingebrigt; Rustan, Arild; Thoresen, G. Hege; Rongved, Pål; Kase, Eili Tranheim.
Synthesis, in vitro and in vivo biological evaluation of new oxysterols as modulators of the liver X receptors. Journal of Steroid Biochemistry and Molecular Biology 2017 ;Volum 165. s. 323-330
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2016
14 Viktorsson, Elvar Örn; Åstrand, Ove Alexander Høgmoen; Bonge-Hansen, Tore; Doskeland, Stein Ove; Herfindal, Lars; Rongved, Pål.
Total synthesis and initial antileukemic evaluation of the phenazine 5,10-dioxide natural products iodinin and myxin. Organisk Kjemisk Vintermøte 2016; 2016-01-07 - 2016-01-10
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15 Åstrand, Ove Alexander Høgmoen; Schnaars, Christian; Kildahl-Andersen, Geir; Rongved, Pål.
Overcoming b-lactam resistance - A potential solution to antibiotic resistance. Organisk Kjemisk Vintermøte 2016; 2016-01-07 - 2016-01-10
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2015
16 Grøthe, Bendik Melling.
Syntese av myxin og myxinderivater som potensielle legemidler mot akutt myelogen leukemi. Kjemisk Institutt: Universitetet i Oslo 2015 155 s.
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17 Grøthe, Bendik Melling; Snellingen, Simen; Viktorsson, Elvar Örn; Prandina, Anthony; Åstrand, Ove Alexander Høgmoen; Bonge-Hansen, Tore; Rongved, Pål.
The first efficient synthesis and preliminary biological effect of the 1,6-dihydroxyphenazine-N5,N10-dioxide (Iodinin) and 1-hydroxy-6-methoxyphenazine-N5,N10-dioxide (Myxin). Organisk Kjemisk Vintermøte 2015; 2015-01-08 - 2015-01-11
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18 Haseeb, Rasha Sabah; Viktorsson, Elvar Örn; Åstrand, Ove Alexander Høgmoen; Rongved, Pål.
Synthetic efforts towards oxysterol-based LXR-modulators. Organisk Kjemisk Vintermøte 2015; 2015-01-08 - 2015-01-11
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19 Prandina, Anthony; Frøvold, Espen; Åstrand, Ove Alexander Høgmoen; Rongved, Pål.
Synthetic efforts towards new agents against resistant bacteria. Organisk Kjemisk Vintermøte 2015; 2015-01-08 - 2015-01-11
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20 Skagseth, Susann; Carlsen, Trine Josefine Olsen; Akhter, Sundus; Zeeshan, Muhammad; Åstrand, Ove Alexander Høgmoen; Bayer, Annette; Rongved, Pål; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S..
The fight against metallo-beta-lactamases and antibiotic resistance. Annual BioStruct Conference, The National graduate school in structural biology; 2015-09-27 - 2015-09-30
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21 Skagseth, Susann; Carlsen, Trine Josefine Olsen; Akhter, Sundus; Zeeshan, Muhammad; Åstrand, Ove Alexander Høgmoen; Bayer, Annette; Rongved, Pål; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S..
The fight against metallo-beta-lactamases and antibiotic resistance. BioStruct Open Day; 2015-03-20 - 2015-03-20
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22 Skagseth, Susann; Carlsen, Trine Josefine Olsen; Christopeit, Tony; Akhter, Sundus; Zeeshan, Muhammad; Åstrand, Ove Alexander Høgmoen; Bayer, Annette; Rongved, Pål; Samulesen, Ørjan; Leiros, Hanna-Kirsti S..
The fight against metallo-beta-lactamases and antibiotic resistance. 51st Norwegian Biochemical Society Contact Meeting, Svalbard; 2015-02-09 - 2015-02-13
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23 Viktorsson, Elvar Örn; Åstrand, Ove Alexander Høgmoen; Haseeb, Rasha Sabah; Gorbitz, Carl Henrik; Rongved, Pål.
Crystal structure of (S)-2-[(3S,8S,9S,10R,13S,14S,-17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,-12,13,14,15,16,17-tetradecahydro-1 H-cyclopenta-[a]phenanthren-17-yl]-N-methoxy-N-methylpro-panamide (Fernholz Weinreb amide). Acta Crystallographica Section E: Structure Reports Online 2015 ;Volum 71.(3) s. 275-277
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24 Viktorsson, Elvar Örn; Åstrand, Ove Alexander Høgmoen; Rustan, Arild; Thoresen, G. Hege; Kase, Eili Tranheim; Rongved, Pål.
Analogs of 22-S-hydroxycholesterol as potential Liver X Receptor-modulators: Synthesis and biological evaluation. Organisk Kjemisk Vintermøte 2015; 2015-01-08 - 2015-01-11
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25 Åstrand, Ove Alexander Høgmoen; Leiros, Hanna-Kirsti S.; Samuelsen, Ørjan; Bayer, Annette; Rongved, Pål.
Overcoming b-lactam resistance - A potential solution to multi-drug resistant bacteria. Organisk Kjemisk Vintermøte 2015; 2015-01-08 - 2015-01-11
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26 Åstrand, Ove Alexander Høgmoen; Rongved, Pål.
OVERCOMING ANTIBIOTIC RESISTANCE - DEVELOPMENT OF NEW MBL INHIBITORS. Frontiers in Medicinal Chemistry; 2015-09-14 - 2015-09-16
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2014
27 Bækkelund Langgård, Øyvind; Burschowsky, Daniel; Rongved, Pål; Krengel, Ute.
Preparing Liver X Receptors for Structural Studies. NBS Kontaktmøte 2014; 2014-01-23 - 2014-01-26
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28 Langgård, Øyvind Bækkelund.
Purification of Liver X Receptors - "A slippery slope through half-charted territory". Oslo: Kjemisk Institutt, Universitetet i Oslo 2014 84 s.
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29 Smith, Robert; Åstrand, Ove Alexander Høgmoen; Nguyen, Luan Minh; Elvestrand, Tina; Hagelin, Gunnar; Solberg, Rigmor; Johansen, Harald Thidemann; Rongved, Pål.
Synthesis of a novel legumain-cleavable colchicine prodrug with cell-specific toxicity. Bioorganic & Medicinal Chemistry 2014 ;Volum 22.(13) s. 3309-3315
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30 Åstrand, Ove Alexander Høgmoen; Gikling, Ingveig; Sylte, Ingebrigt; Rustan, Arild; Thoresen, G. Hege; Rongved, Pål; Kase, Eili Tranheim.
Development of new LXR modulators that regulate LXR target genes and reduce lipogenesis in human cell models. European Journal of Medicinal Chemistry 2014 ;Volum 74. s. 258-263
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31 Åstrand, Ove Alexander Høgmoen; Sandberg, Marcel; Sylte, Ingebrigt; Gorbitz, Carl Henrik; Thoresen, G. Hege; Kase, Eili Tranheim; Rongved, Pål.
Synthesis and initial biological evaluation of new mimics of the LXR-modulator 22(S)-hydroxycholesterol. Bioorganic & Medicinal Chemistry 2014 ;Volum 22.(1) s. 643-650
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2013
32 Bækkelund Langgård, Øyvind; Burschowsky, Daniel; Rongved, Pål; Krengel, Ute.
Preparing Liver X Receptor for Structural Studies. 4th annual BioStruct conference 2013; 2013-08-29 - 2013-09-01
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33 Bækkelund Langgård, Øyvind; Grøthe, Bendik H.; Bousquet, Paula; Burschowsky, Daniel; Rongved, Pål; Krengel, Ute.
Preparing Liver X Receptors for Structural Studies. Norwegian Biochemical Society Contact Meeting 2013; 2013-01-31 - 2013-02-03
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34 Petter Arnt, Hals; Sontum, Per-Christian; Holtz, Eckardt; Klaveness, Jo; Rongved, Pål.
In Vivo Cleavage Rate of a Dextran-Bound Magnetic Resonance Imaging Contrast Agent: Preparation and Intravascular Pharmacokinetic Characteristics in the Rabbit. Current Drug Delivery 2013 ;Volum 10.(1) s. 134-143
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35 Rongved, Pål; Kirsch, Gilbert; Bouaziz, Zouhair; Jose, Joachim; Le Borgne, Marc.
Indenoindoles and cyclopentacarbazoles as bioactive compounds: Synthesis and biological applications. European Journal of Medicinal Chemistry 2013 ;Volum 69. s. 465-479
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36 Tina, Elvestrand; Åstrand, Ove Alexander; Smith, Robert; Rongved, Pål; Nilsen, Hilde; Solberg, Rigmor; Johansen, Harald Thidemann.
Cellular effects of a colchicine-prodrug cleaved by legumain. Vintermøte i Norsk Selskap for Farmakologi og Toksikologi (NSFT); 2013-01-24 - 2013-01-27
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37 Åstrand, Ove Alexander; Aziz, Gul zeb; Ali, Sidra Farzand; Paulsen, Ragnhild Elisabeth; Hansen, Trond Vidar; Rongved, Pål.
Synthesis and initial in vitro biological evaluation of two new zinc-chelating compounds: Comparison with TPEN and PAC-1. Bioorganic & Medicinal Chemistry 2013 ;Volum 21.(17) s. 5175-5181
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38 Åstrand, Ove Alexander Høgmoen; Austdal, Lars Peter Engeset; Paulsen, Ragnhild Elisabeth; Hansen, Trond Vidar; Rongved, Pål.
Synthesis and characterization of new selective Zn2+ fluorescent probes for functionalization: in vitro Cell imaging applications. Tetrahedron 2013 ;Volum 49.(40) s. 8645-8654
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39 Åstrand, Ove Alexander Høgmoen; Gorbitz, Carl Henrik; Kristoffersen, Kenneth Aase; Rongved, Pål.
Acetonitrile){2-[bis(pyridin-2-ylmethyl-κ2 N)amino-κN]-N-(2,6-dimethylphenyl)acetamide-κO}(perchlorato-κO)zinc (acetonitrile){2-[bis(pyridin-2-ylmethyl-κ2 N)amino-κN]-N-(2,6-dimethylphenyl)acetamide-κO}zinc tris(perchlorate). Acta Crystallographica Section E: Structure Reports Online 2013 ;Volum 69.(2) s. m112-m113
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40 Åstrand, Ove Alexander; Iqbal, Zeshan; Sandberg, Marcel; Kase, Eili Tranheim; Gorbitz, Carl Henrik; Rongved, Pål.
(2S,3S)-2,6-Dimethylheptane-1,3-diol, the oxygenated side chain of 22(S)-hydroxycholestrol, and its synthetic precursor (R)-4-benzyl-3-[(2R,3S)-3-hydroxy-2,6-dimethylheptanoyl]-1,3-oxazolidin-2-one. Acta Crystallographica Section C: Crystal Structure Communications 2013 ;Volum 69. s. 647-+
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2011
41 Borhaug, Hilde; Kristensen, Mette; Brudeli, Bjarne; Sontum, Per Chrisian; Klaveness, Jo; Rongved, Pål.
Water-soluble omega-3: A concept for purification of fish oil and nutraceuticals?. European Journal of Lipid Science and Technology 2011 ;Volum 113.(10) s. 1235-1242
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42 Hoff, Lars; Foss, Per A.; Dyrstad, Knut; Klaveness, Jo; Rongved, Pål.
Stabilization of gas bubbles released from water-soluble carbohydrates using amphiphilic compounds: preparation of formulations and acoustic monitoring of bubble lifetime. Journal of Surfactants and Detergents (JSD) 2011 ;Volum 14.(4) s. 585-593
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43 Jacobsen, Øyvind; Gebreslasie, Hadgu G; Klaveness, Jo; Rongved, Pål; Gorbitz, Carl Henrik.
N-(tert-Butoxycarbonyl)-L-valyl-L-valine methyl ester: a twisted parallel beta-sheet in the crystal structure of a protected dipeptide. Acta Crystallographica Section C: Crystal Structure Communications 2011 ;Volum 67. s. O278-O282
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44 Jacobsen, Øyvind; Maekawa, Hiroaki; Ge, Nien-Hui; Gorbitz, Carl Henrik; Rongved, Pål; Ottersen, Ole Petter; Amiry-Moghaddam, Mahmood; Klaveness, Jo.
Stapling of a 3(10)-Helix with Click Chemistry. Journal of Organic Chemistry 2011 ;Volum 76.(5) s. 1228-1238
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45 Åstrand, Ove Alexander; Hansen, Trond Vidar; Rongved, Pål.
Synthesis of new zinc2+ chelating molecules. Organisk Kjemisk Vintermøte 2011; 2011-01-06 - 2011-01-08
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2010
46 Jacobsen, Øyvind; Klaveness, Jo; Rongved, Pål.
Structural and pharmacological effects of ring-closing metathesis in peptides. Molecules 2010 ;Volum 15.(9) s. 6638-6677
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47 Åstrand, Ove Alexander; Hansen, Trond Vidar; Rongved, Pål.
Development of new selctive chelating agents for zinc. Organisk Kjemisk Vintermøte 2010; 2010-01-07 - 2010-01-09
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2009
48 Høyem, Sverre; Bruheim, Skjalg; Mælandsmo, Gunhild M; Standal, Marius; Olberg, Dag Erlend; Brudeli, Bjarne; Åsberg, Anders; Klaveness, Jo; Rongved, Pål.
Didanosine ester prodrugs: Synthesis, albumin binding properties and pharmacokinetic studies in rats. European Journal of Medicinal Chemistry 2009 ;Volum 44.(10) s. 3874-3879
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49 Jacobsen, Øyvind; Klaveness, Jo; Ottersen, Ole Petter; Amiry-Moghaddam, Mahmood Reza; Rongved, Pål.
Synthesis of cyclic peptide analogues of the 3(10) helical Pro138-Gly144 segment of human aquaporin-4 by olefin metathesis. Organic and biomolecular chemistry 2009 ;Volum 7.(8) s. 1599-1611
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2008
50 Jacobsen, Øyvind; Klaveness, Jo; Ottersen, Ole Petter; Mahmood reza, Amiry-Moghaddam; Rongved, Pål.
Synthesis of cyclic peptide analogues of the 310 helical Pro138-Gly144 segment of human aquaporin-4 by olefin metathesis. OKV; 2008-01-08 - 2008-01-12
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