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Showing results 1-46 of 46

2020
1 Abelein, Axel; Chen, Gefei; Kitoka, Kristine; Alexis, Rihards; Oleskovs, Filips; Sarr, Médoune; Landreh, Michael; Pahnke, Jens; Nordling, Kerstin; Kronqvist, Nina; Jaudzems, Kristaps; Rising, Anna; Johansson, Jan; Biverstål, Henrik.
High-yield Production of Amyloid-β Peptide Enabled by a Customized Spider Silk Domain. Scientific Reports 2020 ;Volume 10:235.(1) p. 1-10
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2 Bascuñana, Pablo; Möhle, Luisa; Brackhan, Mirjam; Pahnke, Jens.
Fingolimod as a Treatment in Neurologic Disorders Beyond Multiple Sclerosis. Drugs in R&D 2020 p. -
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3 Borovkova, Mariia; Bykov, Alexander; Popov, Alexey; Pierangelo, Angelo; Novikova, Tatiana; Pahnke, Jens; Meglinski, Igor.
Evaluating β-amyloidosis progression in Alzheimer's disease with Mueller polarimetry. Biomedical Optics Express 2020 ;Volume 11.(8) p. 4509-4519
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4 Borovkova, Mariia; Bykov, Alexander; Popov, Alexey; Pierangelo, Angelo; Novikova, Tatiana; Pahnke, Jens; Meglinski, Igor.
The use of Stokes-Mueller polarimetry for assessment of amyloid-β progression in a mouse model of Alzheimer’s disease. Proceedings of SPIE, the International Society for Optical Engineering 2020 ;Volume 11234:112340M. p. 1-6
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5 Kolnes, Anders Jensen; Øystese, Kristin Astrid; Dahlberg, Daniel; Berg-Johnsen, Jon; Niehusmann, Pitt; Pahnke, Jens; Bollerslev, Jens; Jørgensen, Anders Palmstrøm.
Cut-off values for sufficient cortisol response to low dose Short Synacthen Test after surgery for non-functioning pituitary adenoma. Acta Neurochirurgica 2020 ;Volume 162.(4) p. 845-852
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6 Möhle, Luisa; Schwarzová, Barbora; Krohn, Markus; Stefan, Sven Marcel; Pahnke, Jens.
Using a qPCR device to screen for modulators of ABC transporter activity: A step-by-step protocol. Journal of pharmacological and toxicological methods 2020 ;Volume 104:106882. p. 1-11
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7 Rai, Surya Prakash; Bascuñana, Pablo; Brackhan, Mirjam; Krohn, Markus; Möhle, Luisa; Paarmann, Kristin; Pahnke, Jens.
Detection and Prediction of Mild Cognitive Impairment in Alzheimer's Disease Mice. Journal of Alzheimer's Disease 2020
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8 Rai, Surya Prakash; Krohn, Markus; Pahnke, Jens.
Early Cognitive Training Rescues Remote Spatial Memory but Reduces Cognitive Flexibility in Alzheimer's Disease Mice. Journal of Alzheimer's Disease 2020 ;Volume 75.(4) p. 1301-1317
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9 Zoufal, Viktoria; Mairinger, Severin; Brackhan, Mirjam; Krohn, Markus; Filip, Thomas; Sauberer, Michael; Stanek, Johann; Wanek, Thomas; Tournier, Nicolas; Bauer, Martin; Pahnke, Jens; Langer, Oliver.
Imaging P-Glycoprotein Induction at the Blood-Brain Barrier of a β-Amyloidosis Mouse Model with 11 C-Metoclopramide PET. Journal of Nuclear Medicine 2020 ;Volume 61.(7) p. 1050-1057
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2019
10 Krohn, Markus; Zoufal, Viktoria; Mairinger, Severin; Wanek, Thomas; Paarmann, Kristin; Brüning, Thomas; Eiriz Delgado, Iván; Brackhan, Mirjam; Langer, Oliver; Pahnke, Jens.
Generation and characterization of an ABCC1 humanized mouse model (hABCC1(flx/flx) with knockout capability. Molecular Pharmacology 2019 ;Volume 96.(2) p. 138-147
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11 Latysheva, Anna; Emblem, Kyrre Eeg; Brandal, Petter; Vik-Mo, Einar O.; Pahnke, Jens; Røysland, Kjetil; Hald, John K; Server, Andrés.
Dynamic susceptibility contrast and diffusion MR imaging identify oligodendroglioma as defined by the 2016 WHO classification for brain tumors: histogram analysis approach. Neuroradiology 2019 ;Volume 61.(5) p. 545-555
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12 Moussavi, Nastaran; Azizullah, Hasina; Pahnke, Jens; Malterud, Karl Egil; Inngjerdingen, Kari Tvete; Wangensteen, Helle.
Greek mountain tea, a medicinal plant from Mediterranean countries and Balkan. 67. International Congress and Meeting, Society for Medicinal Plant and Natural Product Research; 2019-09-01 - 2019-09-05
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13 Moussavi, Nastaran; Azizullah, Hasina; Pahnke, Jens; Malterud, Karl Egil; Inngjerdingen, Kari Tvete; Wangensteen, Helle.
Greek mountain tea, a medicinal plant from the Mediterranean countries and Balkan.. Nordic Natural Products conference; 2019-06-09 - 2019-06-12
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14 Zoufal, Viktoria; Mairinger, Severin; Krohn, Markus; Wanek, Thomas; Filip, Thomas; Sauberer, Michael; Stanek, Johann; Kuntner, Claudia; Pahnke, Jens; Langer, Oliver.
Measurement of cerebral ABCC1 transport activity in wild-type and APP/PS1-21 mice with positron emission tomography. Journal of Cerebral Blood Flow and Metabolism 2019 ;Volume 40.(5) p. 954-965
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2018
15 Azizullah, Hasina; Pahnke, Jens; Moussavi, Nastaran; Malterud, Karl Egil; Wangensteen, Helle.
Gresk fjellte, en medisinplante fra middelhavslandene og Balkan. Farmasidagene 2018; 2018-11-06 - 2018-11-08
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16 Bernstein, Hans-Gert; Hildebrandt, J.; Dobrowolny, Henrik; Steiner, J.; Bogerts, Bernhard; Pahnke, Jens.
Corrigendum to 'Morphometric analysis of the cerebral expression of ATP-binding cassette transporter protein ABCB1 in chronic schizophrenia: Circumscribed deficits in the habenula' [Schizophr. Res. 2016 Nov;177(1?3):52?58] (S0920996416300901) (10.1016/j.schres.2016.02.036)). Schizophrenia Research 2018 ;Volume 197. p. 622-623
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17 Ceafalan, Laura Cristina; Fertig, Tudor Emanuel; Gheorghe, Teodora Cristina; Hinescu, Mihail Eugen; Popescu, Bogdan Ovidiu; Pahnke, Jens; Gherghiceanu, Mihaela.
Age‐related ultrastructural changes of the basement membrane in the mouse blood‐brain barrier. Journal of Cellular and Molecular Medicine 2018 ;Volume 23.(2) p. 819-827
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18 Chee, Yuemin Celina; Pahnke, Jens; Bunte, Ralph; Adsool, Vikrant A; Madan, Babita; Virshup, David M.
Intrinsic Xenobiotic Resistance of the Intestinal Stem Cell Niche. Developmental Cell 2018 ;Volume 46.(6) p. 681-695.e5
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19 Krohn, Markus; Wanek, Thomas; Menet, Marie-Claude; Noack, Andreas; Declèves, Xavier; Langer, Oliver; Löscher, Wolfgang; Pahnke, Jens.
Humanization of the Blood-Brain Barrier Transporter ABCB1 in Mice Disrupts Genomic Locus - Lessons from Three Unsuccessful Approaches. European Journal of Microbiology and Immunology 2018 ;Volume 8.(3) p. 78-86
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20 Lamartinière, Yordenca; Boucau, Marie-Christine; Dehouck, Lucie; Krohn, Markus; Pahnke, Jens; Candela, Pietra; Gosselet, Fabien; Fenart, Laurence.
ABCA7 Downregulation Modifies Cellular Cholesterol Homeostasis and Decreases Amyloid-β Peptide Efflux in an in vitro Model of the Blood-Brain Barrier. Journal of Alzheimer's Disease 2018 ;Volume 64.(4) p. 1195-1211
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21 Latysheva, Anna; Emblem, Kyrre Eeg; Server, Andrés; Brandal, Petter; Meling, Torstein Ragnar; Pahnke, Jens; Hald, John K.
Survival associations using perfusion and diffusion magnetic resonance imaging in patients with histologic and genetic defined diffuse glioma World Health Organization grades II and III. Journal of computer assisted tomography 2018 ;Volume 42.(5) p. 807-815
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22 Leske, Henning; Rushing, Elisabeth; Budka, Herbert; Niehusmann, Pitt; Pahnke, Jens; Panagopoulos, Ioannis.
K27/G34 versus K28/G35 in histone H3-mutant gliomas: A note of caution. Acta Neuropathologica 2018 ;Volume 136. p. 175-176
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23 Mairinger, Severin; Zoufal, Viktoria; Wanek, Thomas; Traxl, Alexander; Filip, Thomas; Sauberer, Michael; Stanek, Johann; Kuntner, Claudia; Pahnke, Jens; Müller, Markus; Langer, Oliver.
Influence of breast cancer resistance protein and P-glycoprotein on tissue distribution and excretion of Ko143 assessed with PET imaging in mice. European Journal of Pharmaceutical Sciences 2018 ;Volume 115. p. 212-222
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24 Paarmann, Kristin; Prakash, Sanjeev; Krohn, Markus; Möhle, Luisa; Brackhan, Mirjam; Brüning, Thomas; Eiriz Delgado, Iván; Pahnke, Jens.
French maritime pine bark treatment decelerates plaque development and improves spatial memory in Alzheimer's disease mice. Phytomedicine 2018 ;Volume 57. p. 39-48
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25 Steffen, Johannes; Stenzel, Jan; Ibrahim, Saleh; Pahnke, Jens.
Short-Term Effects of Microglia-Specific Mitochondrial Dysfunction on Amyloidosis in Transgenic Models of Alzheimer's Disease. Journal of Alzheimer's Disease 2018 ;Volume 65.(2) p. 465-474
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26 Storck, Steffen E.; Hartz, Anika M.S.; Bernard, Jessica; Wolf, Andreas; Kachlmeier, André; Mahringer, Anne; Weggen, Sascha; Pahnke, Jens; Pietrzik, Claus U..
The concerted amyloid-beta clearance of LRP1 and ABCB1/P-gp across the blood-brain barrier is linked by PICALM. Brain, behavior, and immunity 2018 ;Volume 73. p. 21-33
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27 Zoufal, Viktoria; Mairinger, Severin; Krohn, Markus; Wanek, Thomas; Filip, Thomas; Sauberer, Michael; Stanek, Johann; Traxl, Alexander; Schuetz, John D; Kuntner, Claudia; Pahnke, Jens; Langer, Oliver.
Influence of Multidrug Resistance-Associated Proteins on the Excretion of the ABCC1 Imaging Probe 6-Bromo-7-[(11)C]Methylpurine in Mice. Molecular Imaging and Biology 2018 p. 1-11
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28 Zoufal, Viktoria; Wanek, Thomas; Krohn, Markus; Mairinger, Severin; Filip, Thomas; Sauberer, Michael; Stanek, Johann; Pekar, Thomas; Bauer, Martin; Pahnke, Jens; Langer, Oliver.
Age dependency of cerebral P-glycoprotein function in wild-type and APPPS1 mice measured with PET. Journal of Cerebral Blood Flow and Metabolism 2018 ;Volume 40.(1) p. 150-162
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2017
29 Aleksis, Rihards; Oleskovs, Filips; Jaudzems, Kristaps; Pahnke, Jens; Biverstål, Henrik.
Structural studies of amyloid-β peptides: Unlocking the mechanism of aggregation and the associated toxicity. Biochimie 2017 ;Volume 140. p. 176-192
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30 Jansone, Baiba; Pahnke, Jens; Biverstål, Henrik.
Alcheimera slimības izpētes aktualitātes. Latvijas ārsts 2017 p. 48-53
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31 Sike, Adam; Wengenroth, Jonas; Upite, Jolanta; Brüning, Thomas; Eiriz Delgado, Iván; Santha, Petra; Biverstål, Henrik; Jansone, Baiba; Haugen, Håvard Jostein; Krohn, Markus; Pahnke, Jens.
Improved method for cannula fixation for long-term intracerebral brain infusion. Journal of Neuroscience Methods 2017 ;Volume 290. p. 145-150
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32 Steffen, Johannes; Krohn, Markus; Schwitlick, christina; Brüning, Thomas; Paarmann, Kristin; Pietrzik, Claus U; Biverstål, Henrik; Jansone, Baiba; Langer, Oliver; Pahnke, Jens.
Expression of endogenous mouse APP modulates β-amyloid deposition in hAPP-transgenic mice.. Acta neuropathologica communications 2017 ;Volume 5.(1) p. -
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2016
33 Möhle, Luisa; Israel, Nicole; Paarmann, Kristin; Krohn, Markus; Pietkiewicz, Sabine; Müller, Andreas; Lavrik, Inna N; Buguliskis, Jeffrey S; Schott, Björn H; Schlüter, Dirk; Gundelfinger, Eckart D; Montag, Dirk; Seifert, Ulrike; Pahnke, Jens; Dunay, Ildiko Rita.
Chronic Toxoplasma gondii infection enhances β-amyloid phagocytosis and clearance by recruited monocytes. Acta neuropathologica communications 2016 ;Volume 4. p. -
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34 Steffen, Johannes; Krohn, Markus; Paarmann, Kristin; Schwitlick, christina; Brüning, Thomas; Marreiros, Rita; Müller-Schiffmann, Andreas; Korth, Carsten; Braun, Katharina; Pahnke, Jens.
Revisiting rodent models: Octodon degus as Alzheimer's disease model?. Acta neuropathologica communications 2016 ;Volume 5.(49)
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35 Bernstein, Hans-Gert; Hildebrandt, Jens; Dobrowolny, Henrik; Steiner, J.; Bogerts, Bernhard; Pahnke, Jens.
Morphometric analysis of the cerebral expression of ATP-binding cassette transporter protein ABCB1 in chronic schizophrenia: Circumscribed deficits in the habenula. Schizophrenia Research 2016 ;Volume 177.(1-3) p. 52-58
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36 Hofrichter, Jacqueline; Krohn, Markus; Schumacher, Toni; Lange, Cathleen; Feistel, Björn; Walbroel, Bernd; Pahnke, Jens.
Sideritis spp. extracts enhance memory and learning in Alzheimer's β-amyloidosis mouse models and aged C57Bl/6 mice. Journal of Alzheimer's Disease 2016 ;Volume 53.(3) p. 967-980
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37 Mairinger, Severin; Wanek, Thomas; Traxl, Alexander; Krohn, Markus; Stanek, Johann; Filip, Thomas; Sauberer, Michael; Kuntner, Claudia; Pahnke, Jens; Langer, Oliver.
7-[11C]methyl-6-bromopurine, a PET tracer to measure brain Mrp1 function: radiosynthesis and first PET evaluation in mice. 32nd International Austrian Winter Symposium, Zell am See, the Netherlands. 20-23 January 2016. EJNMMI Research 2016 ;Volume 6.(32) Suppl. 1
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38 Marques, Fernanda; Sousa, Joao Carlos; Brito, Maria Alexandra; Pahnke, Jens; Santos, Cecilia; Correia-Neves, Margarida; Palha, Joana Almeida.
The choroid plexus in health and in disease: dialogues into and out of the brain. Neurobiology of Disease 2016 (107) p. 32-40
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2015
39 Fröhlich, Christina; Zschiebsch, Katja; Gröger, Victoria; Paarmann, Kristin; Steffen, Johannes; Thurm, Christoph; Schropp, Eva-Maria; Brüning, Thomas; Gellerich, Frank; Radloff, Martin; Schwabe, Rainer; Lachmann, Ingolf; Krohn, Markus; Ibrahim, Saleh; Pahnke, Jens.
Activation of Mitochondrial Complex II-Dependent Respiration Is Beneficial for α-Synucleinopathies. Molecular Neurobiology 2015 ;Volume Published ahead of print. p. -
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40 Krohn, Markus; Bracke, Alexander; Avchalumov, Yosef; Schumacher, Toni; Hofrichter, Jacqueline; Paarmann, Kristin; Fröhlich, Christina; Lange, Cathleen; Brüning, Thomas; Von Bohlen und Halbach, Oliver; Pahnke, Jens.
Accumulation of murine amyloid-β mimics early Alzheimer's disease. Brain 2015 ;Volume 138.(8) p. 2370-2382
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41 Apostolova, Ivayla; Niedzielska, Dagmara; Derlin, Thorsten; Koziolek, Eva J.; Amthauer, Holger; Salmen, Benedikt; Pahnke, Jens; Brenner, Winfried; Mautner, Victor F.; Buchert, Ralph.
Perfusion single photon emission computed tomography in a mouse model of neurofibromatosis type 1: Towards a biomarker of neurologic deficits. Journal of Cerebral Blood Flow and Metabolism 2015 ;Volume 35.(8) p. 1304-1312
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42 Budworth, Helen; Harris, Faye R.; Williams, Paul; Lee, Do Yup; Holt, Amy; Pahnke, Jens; Szczesny, Bartosz; McMurray, Cynthia T.; Acevedo-Torres, Karina; Ayala-Peña, Sylvette.
Suppression of somatic expansion delays the onset of pathophysiology in a mouse model of Huntington’s disease. PLoS Genetics 2015 ;Volume 11:e1005267.(8) p. -
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43 Lill, Christina M.; Rengmark, Aina Sylvia Haugen; Pihlstrøm, Lasse; Fogh, Isabella; Shatunov, Aleksey; Sleiman, Patrick M.; Wang, Li-San; Liu, Tian; Lassen, Christina F.; Meissner, Esther; Alexopoulos, Panos; Calvo, Andrea; Chio, Adriano; Dizdar, Nil; Faltraco, Frank; Forsgren, Lars; Kirchheiner, Julia; Kurz, Alexander; Larsen, Jan Petter; Liebsch, Maria; Linder, Jan; Morrison, Karen E; Nissbrandt, Hans; Otto, Markus; Pahnke, Jens; Partch, Amanda; Restagno, Gabriella; Rujescu, Dan; Schnack, Cathrin; Shaw, Christopher E.; Shaw, Pamela J.; Tumani, Hayrettin; Tysnes, Ole-Bjørn; Valladares, Otto; Silani, Vincenzo; van den Berg, Leonard H.; Van Rheenen, Wouter; Veldink, Jan H.; Lindenberger, Ulman; Steinhagen-Thiessen, Elisabeth; Teipel, Stefan; Perneczky, Robert; Hakonarson, Hakon; Hampel, Harald; Von Arnim, Christine A.F.; Olsen, Jørgen H.; Van Deerlin, Vivianna M.; Al-Chalabi, Ammar; Toft, Mathias; Ritz, Beate; Bertram, Lars.
The role of TREM2 R47H as a risk factor for Alzheimer’s disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson’s disease. Alzheimer's & Dementia 2015 ;Volume 11.(12) p. 1407-1416
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44 Wanek, Thomas; Römermann, Kerstin; Mairinger, Severin; Stanek, Johann; Sauberer, Michael; Filip, Thomas; Traxl, Alexander; Kuntner, Claudia; Pahnke, Jens; Bauer, Florian; Erker, Thomas; Löscher, Wolfgang; Müller, Markus; Langer, Oliver.
Factors governing P-glycoprotein-mediated drug-drug interactions at the blood-brain barrier measured with positron emission tomography. Molecular Pharmaceutics 2015 ;Volume 12.(9) p. 3214-3225
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2014
45 Bernstein, Hans-Gert; Hölzl, Gloria; Dobrowolny, Henrik; Hildebrandt, Jens; Trubner, Kurt; Krohn, Markus; Bogerts, Bernhard; Pahnke, Jens.
Vascular and extravascular distribution of the ATP-binding cassette transporters ABCB1 and ABCC1 in aged human brain and pituitary. Mechanisms of Ageing and Development 2014 ;Volume 141. p. 12-21
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46 Pahnke, Jens; Fröhlich, Christina; Paarmann, Kristin; Krohn, Markus; Bogdanovic, Nenad; Aarsland, Dag; Winblad, Bengt.
Cerebral ABC Transporter-common Mechanisms May Modulate Neurodegenerative Diseases and Depression in Elderly Subjects. Archives of Medical Research 2014 ;Volume 45.(8) p. 738-743
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