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Showing results 1-50 of 97 << Previous 1 2    Next >>

2020
1 Falnes, Pål Øystein.
Novel human methyltransferases - roles in mitochondrial respiration, protein synthesis and beyond. Departmental lecture; 2020-05-11 - 2020-05-11
UiO Untitled
 
2019
2 Falnes, Pål Øystein.
Identification and characterisation of novel human methyltransferases. "Tuesday seminar"; 2019-10-29 - 2019-10-29
UiO Untitled
 
3 Falnes, Pål Øystein.
Modulation of human mitochondrial metabolism by novel lysine-specific methyltransferases. EMBO | EMBL Symposium: Metabolism Meets Epigenetics; 2019-11-20 - 2019-11-23
UiO Untitled
 
4 Falnes, Pål Øystein.
"Nobelprisen i kjemi 2018" (om dirigert evolusjon). Norsk Kjemisk Selskaps årsmøte; 2019-02-27 - 2019-02-27
UiO Untitled
 
5 Falnes, Pål Øystein.
Regulation of protein synthesis through methylation of human eukaryotic elongation factor 1 alpha (eEF1A). Norwegian Biochemical Society 55th Contact Meeting; 2019-01-24 - 2019-01-27
UiO Untitled
 
6 Malecki, Jedrzej Mieczyslaw; Willemen, Hanneke L.D.M.; Pinto, Rita; Ho, Angela Yeuan Yen; Moen, Anders; Eijkelkamp, Niels; Falnes, Pål Øystein.
Human FAM173A is a mitochondrial lysine-specific methyltransferase that targets adenine nucleotide translocase and affects mitochondrial respiration. Journal of Biological Chemistry 2019 ;Volume 294.(31) p. 11654-11664
UiO Untitled
 
7 Pinto, Rita; Vågbø, Cathrine Broberg; Jakobsson, Magnus; Yeji, Kim; Baltissen, Marijke P; O'Donohue, Marie-Francoise; Guzman, Ulises H; Malecki, Jedrzej Mieczyslaw; Wu, Jie; Kirpekar, Finn; Olsen, Jesper V; Gleizes, Pierre-Emmanuel; Vermeulen, Michiel; Leidel, Sebastian A.; Slupphaug, Geir; Falnes, Pål Øystein.
The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA. Nucleic Acids Research (NAR) 2019 ;Volume 48.(2) p. 830-846
NTNU STO UiO Untitled
 
2018
8 Falnes, Pål Øystein.
Discovering new human enzymes involved in methylation and demethylation of nucleic acids and proteins. Foredrag for PhD studenter og forskere; 2018-02-26
UiO Untitled
 
9 Falnes, Pål Øystein.
Regulation of human eukaryotic elongation factor 1 alpha (eEF1A) by lysine methylation. FASEB Science Research Conferences: "Biological methylation"; 2018-06-17 - 2018-06-22
UiO Untitled
 
10 Jakobsson, Magnus; Malecki, Jedrzej Mieczyslaw; Falnes, Pål Øystein.
Regulation of eukaryotic elongation factor 1 alpha (eEF1A) by dynamic lysine methylation. RNA Biology 2018 ;Volume 15.(3) p. 314-319
UiO Untitled
 
11 Jakobsson, Magnus; Malecki, Jedrzej Mieczyslaw; Halabelian, Levon; Nilges, Benedikt S.; Pinto, Rita; Kudithipudi, Srikanth; Munk, Stephanie; Davydova, Erna; Zuhairi, Fawsi Rahmadiyan; Arrowsmith, Cheryl H; Jeltsch, Albert; Leidel, Sebastian A.; Olsen, Jesper V.; Falnes, Pål Øystein.
The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates. Nature Communications 2018 ;Volume 9:3411. p. 1-15
UiO Untitled
 
12 Malecki, Jedrzej Mieczyslaw; Willemen, Hanneke L.D.M.; Pinto, Rita; Ho, Angela Yeuan Yen; Moen, Anders; Kjønstad, Ingrid Fadum; Burgering, Boudewijn M.T.; Zwartkruis, Fried; Eijkelkamp, Niels; Falnes, Pål Øystein.
Lysine methylation by the mitochondrial methyltransferase FAM173B optimizes the function of mitochondrial ATP synthase. Journal of Biological Chemistry 2018 ;Volume 294.(4) p. 1128-1141
UiO Untitled
 
13 Willemen, Hanneke L.D.M.; Kavelaars, Annemieke; Prado, Judith; Maas, MIrjam; Versteeg, Sabine; Nellissen, Lara J.J.; Tromp, Jeshua; Gonzalez Cano, Rafael; Zhou, Wenjun; Jakobsson, Magnus; Malecki, Jedrzej Mieczyslaw; Posthuma, George; Habib, Abdella; Heijnen, Cobi J.; Falnes, Pål Øystein; Eijkelkamp, Niels.
Identification of FAM173B as a protein methyltransferase promoting chronic pain. PLoS Biology 2018 ;Volume 16.(2) p. -
UiO Untitled
 
2017
14 Aileni, Vinay Kumar; Davydova, Erna; Moen, Anders; Falnes, Pål.
A System for Enzymatic Lysine Methylation in a Desired Sequence Context. ACS Omega 2017 ;Volume 2.(2) p. 462-469
UiO Untitled
 
15 Falnes, Pål.
Identification and characterisation of lysine-specific methyltransferases in humans. NBS Kontaktmøte; 2017-01-20
UiO Untitled
 
16 Jakobsson, Magnus; Malecki, Jedrzej Mieczyslaw; Nilges, Benedikt S.; Moen, Anders; Leidel, Sebastian A.; Falnes, Pål.
Methylation of human eukaryotic elongation factor alpha (eEF1A) by a member of a novel protein lysine methyltransferase family modulates mRNA translation. Nucleic Acids Research (NAR) 2017 ;Volume 45. p. 8239-8254
UiO Untitled
 
17 Malecki, Jedrzej Mieczyslaw; Aileni, Vinay Kumar; Ho, Angela Yeuan Yen; Schwarz, Juliane; Moen, Anders; Sørensen, Vigdis; Nilges, Benedikt S.; Jakobsson, Magnus; Leidel, Sebastian A.; Falnes, Pål.
The novel lysine specific methyltransferase METTL21B affects mRNA translation through inducible and dynamic methylation of Lys-165 in human eukaryotic elongation factor 1 alpha (eEF1A). Nucleic Acids Research (NAR) 2017 ;Volume 45.(8) p. 4370-4389
OUS UiO Untitled
 
18 Malecki, Jedrzej Mieczyslaw; Jakobsson, Magnus; Ho, Angela Yeuan Yen; Moen, Anders; Rustan, Arild; Falnes, Pål.
Uncovering human METTL12 as a mitochondrial methyltransferase that modulates citrate synthase activity through metabolite-sensitive lysine methylation. Journal of Biological Chemistry 2017 ;Volume 292.(43) p. 17950-17962
UiO Untitled
 
2016
19 Aileni, Vinay Kumar; Davydova, Erna; Kernstock, Jens Stefan; Moen, Anders; Falnes, Pål.
VCP-KMT (METTL21D)-mediated lysine methylation of histone H3 peptide sequences grafted onto a VCP-derived scaffold. "Biological methylation: Fundamental mechanisms in health and disease"; 2016-06-21
UiO Untitled
 
20 Falnes, Pål.
Lysine methylation of non-histone proteins - new enzymes, new functions. Departmental seminar; 2016-04-19
UiO Untitled
 
21 Falnes, Pål.
Metylering av DNA og proteiner - både skadelig og nødvendig. BIO-torsdag; 2016-09-29
UiO Untitled
 
22 Falnes, Pål; Jakobsson, Magnus; Davydova, Erna; Ho, Angela Yeuan Yen; Malecki, Jedrzej Mieczyslaw.
Protein lysine methylation by seven-β-strand methyltransferases. Biochemical Journal 2016 ;Volume 473.(14) p. 1995-2009
UiO Untitled
 
23 Jakobsson, Magnus; Moen, Anders; Davidson, Ben; Falnes, Pål.
METTL21A-catalysed lysine methylation of Hsp70 proteins. "Biological methylation: Fundamental mechanisms in health and disease; 2016-06-20
UiO Untitled
 
24 Jakobsson, Magnus; Moen, Anders; Falnes, Pål.
Correspondence: On the enzymology and significance of HSPA1 lysine methylation. Nature Communications 2016 ;Volume 7.
UiO Untitled
 
25 Malecki, Jedrzej Mieczyslaw; Dahl, Helge-Andre; Moen, Anders; Davydova, Erna; Falnes, Pål.
The METTL20 homologue from agrobacterium tumefaciens is a dual specificity protein-lysine methyltransferase that targets ribosomal protein L7/L12 and the β subunit of electron transfer flavoprotein (ETFβ). Journal of Biological Chemistry 2016 ;Volume 291.(18) p. 9581-9595
UiO Untitled
 
2015
26 Falnes, Pål.
Discovering new human enzymes involved in methylation and demethylation of nucleic acids and proteins. Departmental seminar; 2015-03-04
UiO Untitled
 
27 Falnes, Pål.
Discovering new human enzymes involved in methylation and demethylation of nucleic acids and proteins. Departmental Seminar; 2015-04-13
UiO Untitled
 
28 Falnes, Pål.
Merkelapper på DNA og proteiner – både skadelig og nødvendig.. "Bestill en kreftforsker"; 2015-11-05
UiO Untitled
 
29 Falnes, Pål.
Metylering av DNA og proteiner– skadelig og nødvendig. Faglig-pedagogisk dag, UiO (for lærere i videregående skole); 2015-10-29
UiO Untitled
 
30 Falnes, Pål; Ho, Angela Yeuan Yen.
Role of ALKBH8 in the Synthesis of Wobble Uridine Modifications in tRNA. I: 2-Oxoglutarate-Dependent Oxygenases. Royal Society of Chemistry 2015 ISBN 978-1-84973-950-4. p. 275-288
UiO Untitled
 
31 Fusser, Markus; Kernstock, Stefan; Aileni, Vinay Kumar; Jacobsen, Wolfgang Mathias; Falnes, Pål; Klungland, Arne.
Lysine methylation of the valosin-containing protein (VCP) is dispensable for development and survival of mice. PLOS ONE 2015 ;Volume 10.(11) p. -
OUS UiO Untitled
 
32 Jakobsson, Magnus; Davydova, Erna; Malecki, Jedrzej Mieczyslaw; Moen, Anders; Falnes, Pål.
Saccharomyces cerevisiae eukaryotic elongation factor 1A (eEF1A) is methylated at Lys-390 by a METTL21-like methyltransferase. PLOS ONE 2015 ;Volume 10.(6)
UiO Untitled
 
33 Jakobsson, Magnus; Moen, Anders; Davidson, Ben; Falnes, Pål.
Hsp70 (HSPA1) lysine methylation status as a potential prognostic factor in metastatic high-grade serous carcinoma. PLOS ONE 2015 ;Volume 10:e0140168.(10)
OUS UiO Untitled
 
34 Malecki, Jedrzej Mieczyslaw; Ho, Angela Yeuan Yen; Moen, Anders; Dahl, Helge-Andre; Falnes, Pål.
Human METTL20 is a mitochondrial lysine methyltransferase that targets the β subunit of electron transfer flavoprotein (ETFβ) and modulates its activity. Journal of Biological Chemistry 2015 ;Volume 290.(1) p. 423-434
UiO Untitled
 
35 Zdzalik, Daria; Domanska, Anna; Prorok, Paulina; Kosicki, Konrad; Van den Born, Erwin; Falnes, Pål; Rizzo, Carmelo J.; Guengerich, F.Peter; Tudek, Barbara.
Differential repair of etheno-DNA adducts by bacterial and human AlkB proteins. DNA Repair 2015 ;Volume 30. p. 1-10
UiO Untitled
 
2014
36 Davydova, Erna; Ho, Angela Yeuan Yen; Malecki, Jedrzej Mieczyslaw; Moen, Anders; Enserink, Jorrit; Jakobsson, Magnus; Loenarz, Christoph; Falnes, Pål.
Identification and characterization of a novel evolutionarily conserved lysine-specific methyltransferase targeting eukaryotic translation elongation factor 2 (eEF2). Journal of Biological Chemistry 2014 ;Volume 289.(44) p. 30499-30510
OUS UiO Untitled
 
37 Falnes, Pål.
Discovering new human enzymes involved in methylation and demethylation of nucleic acids and proteins. Biochemistry Department Seminar; 2014-12-10 - 2014-12-10
UiO Untitled
 
38 Falnes, Pål.
Functional characterization of a novel family of protein lysine methyltransferases. FASEB Science Research Conference on Biological Methylation; 2014-07-06 - 2014-07-12
UiO Untitled
 
39 Zdzalik, Daria; Vågbø, Cathrine Broberg; Kirpekar, F; Davydova, Erna; Puścian, Alicja; Maciejewska, Agnieszka M.; Krokan, Hans Einar; Klungland, Arne; Tudek, Barbara; Van den Born, Erwin; Falnes, Pål.
Protozoan ALKBH8 Oxygenases Display both DNA Repair and tRNA Modification Activities. PLOS ONE 2014 ;Volume 9.(6)
NTNU OUS UiO Untitled
 
2013
40 Jakobsson, Magnus; Moen, Anders; Bousset, Luc; Jacobsen, Wolfgang Mathias; Kernstock, Jens Stefan; Melki, Ronald; Falnes, Pål.
Identification and characterization of a novel human methyltransferase modulating hsp70 Protein function through lysine methylation. Journal of Biological Chemistry 2013 ;Volume 288.(39) p. 27752-27763
UiO Untitled
 
41 Falnes, Pål.
Role of the bifunctional ALKBH8 enzyme in the formation of modified wobble uridines in tRNA. Barcelona BioMed Conference Gene Translation: Fidelity and Quality Control; 2013-12-01 - 2013-12-04
UiO Untitled
 
42 Lin, Fu-Jung; Shen, Li; Jang, Chuan-Wei; Falnes, Pål; Zhang, Yi.
Ikbkap/Elp1 Deficiency Causes Male Infertility by Disrupting Meiotic Progression. PLoS Genetics 2013 ;Volume 9.(5) p. -
UiO Untitled
 
2012
43 Bjørnstad, Linn; Meza, Trine Johansen; Otterlei, Marit; Olafsrud, Solveig Mjelstad; Meza-Zepeda, Leonardo Andrés; Falnes, Pål.
Human ALKBH4 Interacts with Proteins Associated with Transcription. PLOS ONE 2012 ;Volume 7.(11) p. -
NTNU OUS UiO Untitled
 
44 Falnes, Pål.
Merkelapper på DNA og proteiner – både skadelig og nødvendig. "Bestill en kreftforsker; 2012-10-24
UiO Untitled
 
45 Falnes, Pål.
Merkelapper på DNA og proteiner –både skadelig og nødvendig. "Bestill en kreftforsker"; 2012-10-22
UiO Untitled
 
46 Kernstock, Jens Stefan; Davydova, Erna; Jakobsson, Magnus; Moen, Anders; Pettersen, Solveig; Mælandsmo, Gunhild; Jacobsen, Wolfgang Mathias; Falnes, Pål.
Lysine methylation of VCP by a member of a novel human protein methyltransferase family. Nature Communications 2012 ;Volume 3. p. -
OUS UiO Untitled
 
47 Korvald, Hanne; Falnes, Pål; Lærdahl, Jon Kristen; Bjørås, Magnar; Alseth, Ingrun.
The Schizosaccharomyces pombe AlkB homolog Abh1 exhibits AP lyase activity but no demethylase activity. DNA Repair 2012 ;Volume 11.(5) p. 453-462
OUS UiO Untitled
 
48 Meza, Trine Johansen; Moen, Marivi; Vågbø, Cathrine Broberg; Krokan, Hans Einar; Klungland, Arne; Grini, Paul Eivind; Falnes, Pål.
The DNA dioxygenase ALKBH2 protects Arabidopsis thaliana against methylation damage. Nucleic Acids Research (NAR) 2012 ;Volume 40.(14) p. 6620-6631
NTNU OUS UiO Untitled
 
2011
49 Bjørnstad, Linn; Zoppellaro, Giorgio; Tomter, Ane Berg; Falnes, Pål; Andersson, K. Kristoffer.
Spectroscopic and Magnetic Studies of wild-type and mutant forms of the FeII and 2-oxoglutarate dependent decarboxylase ALKBH4. Biochemical Journal 2011 ;Volume 434.(3) p. 391-398
UiO Untitled
 
50 Bjørnstad, Linn; Zoppellaro, Giorgio; Tomter, Ane Berg; Falnes, Pål; Andersson, K. Kristoffer.
Spectroscopic and Magnetic Studies of wild-type and mutant forms of the FeII and 2-oxoglutarate dependent decarboxylase ALKBH4. Gordon Research Conferences, Conference: Metals in Biology, Ventura California; 2011-01-30 - 2010-02-04; 2011-01-30 - 2011-02-04
UiO Untitled
 
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