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Showing results 1-50 of 106 << Previous 1 2 3    Next >>

2020
1 Ciyow, Nasra; Bosnjak, Tatjana; Nilsen, Hilde; Lunde, Ngoc Nguyen; Johansen, Harald Thidemann; Solberg, Rigmor.
Effekt av teriparatid på differensiering og regulering av cysteinproteaser i osteoblaster. NSFT-vintermøte; 2020-01-23 - 2020-01-26
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2 Mohanachandran, Arthii; Bosnjak, Tatjana; Nilsen, Hilde; Lunde, Ngoc Nguyen; Solberg, Rigmor; Johansen, Harald Thidemann.
Differensiering av RAW264.7 til osteoklaster og karakterisering av cysteinproteaser i osteoklaster. NSFT-vintermøte; 2020-01-23 - 2020-01-26
UiO Untitled
 
3 Olsen, Kristine Løkke; Johansen, Harald Thidemann; Nilsen, Hilde; Solberg, Rigmor; Berg, Kristian.
Effekt av cysteinproteasen legumain på celleviabilitet etter fotodynamisk terapi. NSFT-vintermøte; 2020-01-23 - 2020-01-26
UiO Untitled
 
2019
4 Awale, Mustafa; Bosnjak, Tatjana; Nilsen, Hilde; Solberg, Rigmor; Johansen, Harald Thidemann.
Effekten av kjønnshormoner på differensiering av stamceller til osteoblaster og regulering av cysteinproteasene legumain og cathepsin B. Vintermøte i Norsk selskap for farmakologi og toksikologi; 2019-01-24 - 2019-01-27
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5 Bosnjak, Tatjana; Solberg, Rigmor; Arnekleiv, Guro L.; Nilsen, Hilde; Jafari, Abbas; Bassatne, A.; Fuleihan, G.E.H.; Kassem, Moustapha; Johansen, Harald Thidemann.
Vitamin D3 upregulates legumain in the early phase of osteoblast differentiation. 11th General Meeting of the International Proteolysis Society; 2019-09-29 - 2019-10-04
UiO Untitled
 
6 Bosnjak, Tatjana; Solberg, Rigmor; Hemati, Paya Diana; Jafari, Abbas; Kassem, Moustapha; Johansen, Harald Thidemann.
Lansoprazole inhibits the cysteine protease legumain by binding to the active site. Basic & Clinical Pharmacology & Toxicology 2019 ;Volume 125.(2) p. 89-99
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7 Lunde, Ngoc Dieu Nguyen; Bosnjak, Tatjana; Solberg, Rigmor; Johansen, Harald Thidemann.
Mammalian legumain - A lysosomal cysteine protease with extracellular functions?. Biochimie 2019 ;Volume 166. p. 77-83
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8 Lunde, Ngoc Dieu Nguyen; Gregersen, Ida; Ueland, Thor; Shetelig, Christian; Holm, Sverre; Kong, Xiang Yi; Michelsen, Annika; Otterdal, Kari; Yndestad, Arne; Broch, Kaspar; Gullestad, Lars; Nyman, Tuula Anneli; Bendz, Bjørn; Eritsland, Jan; Hoffmann, Pavel; Skagen, Karolina Ryeng; Gonçalves, Isabel; Nilsson, Jan; Grenegård, Magnus; Poreba, Marcin; Drag, Marcin; Seljeflot, Ingebjørg; Sporsheim, Bjørnar; Espevik, Terje; Skjelland, Mona; Johansen, Harald Thidemann; Solberg, Rigmor; Aukrust, Pål; Björbacka, Harry; Andersen, Geir Øystein; Halvorsen, Bente.
Legumain is upregulated in acute cardiovascular events and associated with improved outcome – potentially related to anti-inflammatory effects on macrophages. Atherosclerosis 2019 p. 1-9
NTNU OUS UiO UiT Untitled
 
9 Pischke, Søren; Hestenes, Siv Merete; Johansen, Harald Thidemann; Fure, Hilde; Bugge, Jan F; Espinoza, Andreas Westenvik; Skulstad, Helge; Edvardsen, Thor; Fosse, Erik; Mollnes, Tom Eirik; Halvorsen, Per Steinar; Nielsen, Erik Waage.
Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model. PLOS ONE 2019 ;Volume 14:e0218624.(6) p. -
NLSH NTNU OUS UiO UiT VV Untitled
 
2018
10 Abbas, Iram; Nilsen, Hilde; Johansen, Harald Thidemann; Solberg, Rigmor.
Deksametason hemmer differensiering av humane mesenkymale stamceller til osteoblaster og regulerer cysteinproteasene legumain og cathepsin B. NSFT vintermøte; 2018-01-25 - 2018-01-28
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11 Bosnjak, Tatjana; Hemati, Paya Diana; Solberg, Rigmor; Johansen, Harald Thidemann.
Cysteine proteases as Targets for Proton Pump Inhibitors (PPIs). Proteolytic Enzymes and Their Inhibitors Gordon Research Conference; 2018-06-03 - 2018-06-08
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12 Gjonbalaj, Nora; Nilsen, Hilde; Solberg, Rigmor; Johansen, Harald Thidemann.
Effekt av inflammasjon på regulering av cysteinproteasene legumain og cathepsin B under differensiering av humane mesenkymale stamceller til osteoblaster. NSFT vintermøte; 2018-01-25 - 2018-01-28
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13 Lunde, Ngoc Nguyen Dieu; Gregersen, Ida; Holm, Sverre; Michelsen, Annika; Sporsheim, Bjørnar; Espevik, Terje; Solberg, Rigmor; Johansen, Harald Thidemann; Halvorsen, Bente.
Platelet-derived legumain, a cysteine protease involved in atherosclerosis. Proteolytic Enzymes and Their Inhibitors Gordon Research Conference; 2018-06-03 - 2018-06-08
NTNU UiO Untitled
 
14 Lunde, Ngoc Nguyen Dieu; Holm, Sverre; Dahl, Tuva Børresdatter; Elyouncha, Inass; Sporsheim, Bjørnar; Gregersen, Ida; Abbas, Azhar; Skjelland, Mona; Espevik, Terje; Solberg, Rigmor; Johansen, Harald Thidemann; Halvorsen, Bente.
Plasma and plaques from patients with carotid atherosclerosis have increased levels of legumain. 24th Annual Scandinavian Atherosclerosis Conference; 2018-04-11 - 2018-04-14
NTNU OSTFSYK UiO Untitled
 
2017
15 Arnekleiv, Guro L.; Nilsen, Hilde; Lunde, Ngoc Nguyen Dieu; Solberg, Rigmor; Johansen, Harald Thidemann.
Effekt av vitamin D3 på uttrykk, aktivitet og sekresjon av cysteinproteasen legumain studert i ulike cellemodeller. Norsk selskap for farmakologi og toksikologi (NSFT) vintermøte; 2017-01-26 - 2017-01-29
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16 Bosnjak, Tatjana; Hemati, Paya Diana; Nilsen, Hilde; Solberg, Rigmor; Johansen, Harald Thidemann.
Legumain as a target for proton pump inhibitors (PPIs): Importance for off-target effects of PPIs?. 10th General Meeting of the International Proteolysis Society (IPS); 2017-10-28 - 2017-11-01
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17 Hemati, Paya Diana; Bosnjak, Tatjana; Nilsen, Hilde; Lunde, Ngoc Nguyen Dieu; Johansen, Harald Thidemann; Solberg, Rigmor.
The Proton Pump Inhibitor Lansoprazole Inhibits Protease Activity of Legumain. Norsk selskap for farmakologi og toksikologi (NSFT) vintermøte; 2017-01-26 - 2017-01-29
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18 Jafari, Abbas; Qanie, Diyako; Andersen, Thomas L.; Zhang, Yuxi; Chen, Li; Postert, Benno; Parsons, Stuart; Ditzel, Nicholas; Khosla, Sundeep; Johansen, Harald Thidemann; Kjærsgaard-Andersen, Per; Delaissé, Jean-Marie; Abdallah, Basem M.; Hesselson, Daniel; Solberg, Rigmor; Kassem, Moustapha.
Legumain regulates differentiation fate of human bone marrow stromal cells and is altered in postmenopausal osteoporosis. Stem Cell Reports 2017 ;Volume 8.(2) p. 373-386
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19 Lunde, Ngoc Nguyen Dieu; Haugen, Mads Haugland; Larsen, Kristina Broe Bodin; Damgaard, Ingrid; Pettersen, Solveig; Kasem, Roya; Rut, Wioletta; Drag, Marcin; Poreba, Marcin; Johansen, Harald Thidemann; Solberg, Rigmor.
Glycosylation is important for legumain localization and processing to active forms but not for cystatin E/M inhibitory functions. Biochimie 2017 ;Volume 139. p. 27-37
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20 Lunde, Ngoc Nguyen Dieu; Holm, Sverre; Dahl, Tuva B.; Elyoncha, Inass; Sporsheim, Bjørnar; Gregersen, Ida; Abbas, Azhar; Skjelland, Mona; Espevik, Terje; Solberg, Rigmor; Johansen, Harald Thidemann; Halvorsen, Bente.
Plasma and plaques from patients with carotid atherosclerosis have increased levels of legumain. 10th General Meeting of the International Proteolysis Society (IPS); 2017-10-28 - 2017-11-01
NTNU OSTFSYK UiO Untitled
 
21 Lunde, Ngoc Nguyen Dieu; Holm, Sverre; Dahl, Tuva Børresdatter; Inass, Elyouncha; Sporsheim, Bjørnar; Gregersen, Ida; Abbas, Azhar; Skjelland, Mona; Espevik, Terje; Solberg, Rigmor; Johansen, Harald Thidemann; Halvorsen, Bente.
Increased levels of legumain in plasma and plaques from patients with carotid atherosclerosis. Atherosclerosis 2017 ;Volume 257. p. 216-223
NTNU OSTFSYK OUS RS UiO Untitled
 
22 Solberg, Rigmor; Bosnjak, Tatjana; Nilsen, Hilde; Jafari, Abbas; Kassem, Moustapha; Johansen, Harald Thidemann.
Regulation of legumain and cysteine cathepsins during differentiation of human bone marrow stromal cells towards osteoblasts. 10th General Meeting of the International Proteolysis Society (IPS); 2017-10-28 - 2017-11-01
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2016
23 Abdukadir, Nuriddin; Lunde, Ngoc Nguyen Dieu; Nilsen, Hilde; Solberg, Rigmor; Johansen, Harald Thidemann.
Regulering av cysteinproteaser ved differensiering av monocytter til makrofager. Norsk selskap for farmakologi og toksikologi vintermøte; 2016-01-28 - 2016-07-01
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24 Johansen, Harald Thidemann.
Type 2 cystatins as inhibitors of legumain. Cystatins 2016; 2016-06-02 - 2016-06-04
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25 Johansen, Harald Thidemann; Seip, Knut Fredrik; Nielsen, Erik Waage.
Bradykininutløste angioødemer. Norsk Farmaceutisk Tidsskrift 2016 ;Volume 124.(4) p. 31-35
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26 Larsen, Kristina Broe Bodin; Johansen, Harald Thidemann; Solberg, Rigmor; Lunde, Ngoc Nguyen Dieu.
Betydning av glykosylering for internalisering og aktivering av prolegumain i humane tykktarmskreftceller. Norsk selskap for farmakologi og toksikologi vintermøte; 2016-01-28 - 2016-01-31
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27 Lunde, Ngoc Nguyen Dieu; Dahl, Tuva Børresdatter; Abdukadir, Nuriddin; Halvorsen, Bente; Solberg, Rigmor; Johansen, Harald Thidemann.
Increased secretion of legumain from pro-inflammatory M1 compared to M2 macrophages. Gordon Research Conference on Proteolytic Enzymes & Their Inhibitors - Exploring and Exploiting Proteases in Development and Disease; 2016-06-25 - 2016-07-01
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28 Manna, Dipankar.
Structure-function characterization and cytotoxicity studies of fungal chimerolectins. : Universitetet i Oslo 2016
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29 Seip, Knut Fredrik; Evjenth, Bjørg; Hovland, Anders; Dybwik, Knut Gustav; Johansen, Harald Thidemann; Fure, Hilde; Mollnes, Tom Eirik; Nielsen, Erik Waage.
Bradykinin-Induced Shock Increase Exhaled Nitric Oxide, Complement Activation and Cytokine Production in Pigs. Journal of Cardiology & Clinical Research 2016 ;Volume 4.(2) p. -
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30 Solberg, Rigmor; Johansen, Harald Thidemann.
Involvement of the cysteine protease legumain in human health and disease. Scientific Colaboration Meeting; 2016-03-16 - 2016-03-16
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2015
31 Berven, Lise; Skjeldal, Frode Miltzow; Prydz, Kristian; Zubaidi, Layla Mohammad Khader; Ballance, Simon; Johansen, Harald Thidemann; Samuelsen, Anne Berit C..
Particulate yeast β-glucan is internalized by RAW 264.7 macrophages and reduces the activity of the tumor-associated protease legumain. Bioactive Carbohydrates and Dietary Fibre 2015 ;Volume 6.(1) p. 15-23
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32 Johansen, Harald Thidemann; Elyouncha, Inass; Lunde, Ngoc Nguyen Dieu; Williams, Rich; Solberg, Rigmor; Nilsen, Hilde; Halvorsen, Bente.
Opposing effects of glucose on legumain and cysteine cathepsins. 9th General Meeting of the International Proteolysis Society; 2015-10-04 - 2015-10-08
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33 Lunde, Ngoc Nguyen Dieu; Nilsen, Hilde; Damgaard, Ingrid; Kasem, Roya; Solberg, Rigmor; Haugen, Mads Haugland; Johansen, Harald Thidemann.
Importance of glycosylation for legumain and cystatin E/M functions. 9th General Meeting of the International Proteolysis Society; 2015-10-04 - 2015-10-08
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34 Nielsen, Erik Waage; Lappegård, Knut Tore; Johansen, Harald Thidemann.
Re: Ny og bedre medisin mot hjertesvikt. Tidsskrift for Den norske legeforening 2015 ;Volume 135.(9) p. 830-831
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2014
35 Seip, Knut Fredrik; Bjerknes, Kari Christiane; Johansen, Harald Thidemann; Nielsen, Erik Waage; Landrø, Linn Aina Ysland; Reubsaet, Leon.
Bradykinin analysis revived - A validated method for determination of its stable metabolite in whole blood by LC-MS/MS. Journal of chromatography. B 2014 ;Volume 947-948. p. 139-144
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36 Smith, Robert; Solberg, Rigmor; Jacobsen, Linn Løkken; Voreland, Anette Larsen; Rustan, Arild; Thoresen, G. Hege; Johansen, Harald Thidemann.
Simvastatin inhibits glucose metabolism and legumain activity in human myotubes. PLOS ONE 2014 ;Volume 9.(1:85721) p. -
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37 Smith, Robert; Åstrand, Ove Alexander Høgmoen; Nguyen, Luan Minh; Elvestrand, Tina; Hagelin, Gunnar; Solberg, Rigmor; Johansen, Harald Thidemann; Rongved, Pål.
Synthesis of a novel legumain-cleavable colchicine prodrug with cell-specific toxicity. Bioorganic & Medicinal Chemistry 2014 ;Volume 22.(13) p. 3309-3315
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38 Solberg, Rigmor; Smith, Robert; Almlöf, Maria; Tewolde, Eyassu Araia; Nilsen, Hilde; Johansen, Harald Thidemann.
Atorvastatin inhibits processing, activity and secretion of legumain in macrophages. Biological chemistry 2014 ;Volume 396.(1) p. 71-80
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39 Solberg, Rigmor; Smith, Robert; Almlöf, Maria; Tewolde, Eyassu Araia; Nilsen, Hilde; Johansen, Harald Thidemann.
Legumain expression, activity and secretion are increased during monocyte-to-macrophage differentiation and inhibited by atorvastatin. Biological chemistry 2014 ;Volume 396.(1) p. 71-80
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2013
40 Berven, Lise; Johansen, Harald Thidemann; Solberg, Rigmor; Kolset, Svein Olav; Samuelsen, Anne Berit C..
Autoactivation of prolegumain is accelerated by glycosaminoglycans. Biochimie 2013 ;Volume 95.(4) p. 772-781
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41 Berven, Lise; Solberg, Rigmor; Truong, Hoa Hong Thi; Arlov, Øystein; Aachmann, Finn Lillelund; Skjåk-Bræk, Gudmund; Jacobsen, Wolfgang Mathias; Johansen, Harald Thidemann; Samuelsen, Anne Berit C..
Alginates induce legumain activity in RAW 264.7 cells and accelerate autoactivation of prolegumain. Bioactive Carbohydrates and Dietary Fibre 2013 ;Volume 2. p. 30-44
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42 Haugen, Mads Haugland; Flatmark, Kjersti; Tamhane, Tripti; Boye, Kjetil; Pettersen, Solveig; Solberg, Rigmor; Johansen, Harald Thidemann; Brix, Klaudia; Mælandsmo, Gunhild.
Nuclear localized legumain in colorectal cancer. 30th Winter School on Proteinases and Inhibitors; 2013-02-27 - 2013-03-03
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43 Haugen, Mads Haugland; Johansen, Harald Thidemann; Pettersen, Solveig; Solberg, Rigmor; Brix, Klaudia; Flatmark, Kjersti; Mælandsmo, Gunhild.
Nuclear Legumain Activity in Colorectal Cancer. PLOS ONE 2013 ;Volume 8.(1)
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44 Johansen, Harald Thidemann; Solberg, Rigmor; Nilsen, Hilde; Smith, Robert.
Effects and interplay of legumain and cystatin E/M om migration and invasion of macrophages. 4th FEBS Advanced Lecture Course; FEBS - MPST 2013; 2013-09-26 - 2013-10-01
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45 Seip, Knut Fredrik; Bjerknes, Kari Christiane; Johansen, Harald Thidemann; Landrø, Linn Aina Ysland; Helsing, Per; Reubsaet, Leon; Nielsen, Erik Waage.
Investigating bradykinin exposure in hereditary angioedema through the metabolite BK1-5. 15th Nordic Conference in Mass Spectrometry; 2013-01-20 - 2013-01-23
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46 Smith, Robert; Johansen, Harald Thidemann; Jacobsen, Linn Løkken; Voreland, Anette Larsen; Rustan, Arild; Thoresen, G. Hege; Solberg, Rigmor.
Simvastatin inhibits legumain activity and processing in human myotubes. 8th General Meeting of the International Proteolysis Society; 2013-10-20 - 2013-10-24
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47 Smith, Robert; Johansen, Harald Thidemann; Nilsen, Hilde; Solberg, Rigmor.
Effects and interplay of legumain and cystatin E/M on migration and invasion of macrophages. 8th General Meeting of the International Proteolysis Society; 2013-10-20 - 2013-10-24
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48 Tina, Elvestrand; Åstrand, Ove Alexander; Smith, Robert; Rongved, Pål; Nilsen, Hilde; Solberg, Rigmor; Johansen, Harald Thidemann.
Cellular effects of a colchicine-prodrug cleaved by legumain. Vintermøte i Norsk Selskap for Farmakologi og Toksikologi (NSFT); 2013-01-24 - 2013-01-27
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49 Voreland, Anette; Smith, Robert; Thoresen, G. Hege; Johansen, Harald Thidemann; Solberg, Rigmor.
The cysteine protease legumain is downregulated by simvastatin in primary human skeletal muscle cells. Vintermøte i Norsk Selskap for Farmakologi og Toksikologi (NSFT); 2013-01-24 - 2013-01-27
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50 Ånonsen, Kjersti Bergh; Nilsen, Hilde; Smith, Robert; Johansen, Harald Thidemann; Solberg, Rigmor.
Regulering av legumain i samspillet mellom makrofager og kreftceller. Vintermøte i Norsk Selskap for Farmakologi og Toksikologi (NSFT); 2013-01-24 - 2013-01-27
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