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Showing results 1-50 of 134 << Previous 1 2 3    Next >>

2020
1 Fan, Qiong; Nørgaard, Rikke Christine; Grytten, Ivar; Ness, Cecilie Maria; Lucas, Christin; Vekterud, Kristin; Soedling, Helen; Matthews, Jason; Lemma, Roza Berhanu; Gabrielsen, Odd Stokke; Bindesbøll, Christian; Ulven, Stine Marie; Nebb, Hilde Irene; Grønning-Wang, Line Mariann; Sæther, Thomas.
LXRα Regulates ChREBPα Transactivity in a Target Gene-Specific Manner through an Agonist-Modulated LBD-LID Interaction. Cells 2020 ;Volume 9.(5)
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2019
2 Arnesen, Liv Henriette; Haj Yasein, Nadia; Tungen, Jørn Eivind; Södling, Helen; Matthews, Jason; Paulsen, Steinar M; Nebb, Hilde Irene; Sylte, Ingebrigt; Hansen, Trond Vidar; Sæther, Thomas.
Molecular modelling, synthesis, and biological evaluations of a 3,5-disubstituted isoxazole fatty acid analogue as a PPARα-selective agonist. Bioorganic & Medicinal Chemistry 2019 ;Volume 27.(18) p. 4059-4068
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3 Fan, Qiong; Nørgaard, Rikke Christine; Grytten, Ivar; Ness, Cecilie Maria; Lucas, Christin; Vekterud, Kristin; Södling, Helen; Matthews, Jason; Lemma, Roza Berhanu; Gabrielsen, Odd Stokke; Bindesbøll, Christian; Ulven, Stine Marie; Nebb, Hilde Irene; Grønning-Wang, Line Mariann; Sæther, Thomas.
LXRα interacts with the glucose-sensing transcription factor ChREBPα to regulate its transcriptional activity.. EMBO | EMBL Symposium: Metabolism Meets Epigenetics; 2019-11-20 - 2019-11-23
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4 Fan, Qiong; Nørgaard, Rikke Christine; Grytten, Ivar; Ness, Cecilie Maria; Lucas, Christin; Vekterud, Kristin; Soedling, Helen; Matthews, Jason; Lemma, Roza Berhanu; Gabrielsen, Odd Stokke; Bindesbøll, Christian; Ulven, Stine Marie; Nebb, Hilde Irene; Grønning-Wang, Line Mariann; Sæther, Thomas.
Open the LID: LXRα regulates ChREBPα transactivity in a target gene-specific manner through an agonist-modulated LBD-LID interaction. BioRxiv 2019 p. -
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2018
5 Fan, Qiong; Nørgaard, Rikke Christine; Grytten, Ivar; Ulven, Stine Marie; Lucas, Christin; Bindesbøll, Christian; Lemma, Roza Berhanu; Gabrielsen, Odd Stokke; Grønning-Wang, Line Mariann; Nebb, Hilde Irene; Sæther, Thomas.
LXRα interacts with the glucose-sensing transcription factor ChREBPα and increases its transcriptional activity. 2018 MolMed Retreat; 2018-10-10 - 2018-10-10
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6 Fan, Qiong; Nørgaard, Rikke Christine; Ulven, Stine Marie; Lucas, Christin; Bindesbøll, Christian; Grønning-Wang, Line Mariann; Nebb, Hilde Irene; Sæther, Thomas.
Exploring the functional importance of a transcriptional cholesterol/sugar switch in liver. 2018 International Conference on Applied Biochemistry and Biotechnology; 2018-06-26 - 2018-06-26
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7 Gomez, Alvin; Bindesbøll, Christian; Somisetty, Venkata Satheesh; Grimaldi, Giulia; Hutin, David; MacPherson, Laura; Ahmed, Shaimaa; Tamblyn, Laura; Cho, Tiffany; Nebb, Hilde Irene; Moen, Anders; Anonsen, Jan Haug; Grant, Denis M; Matthews, Jason.
Characterization of TCDD-inducible poly-ADP-ribose polymerase (TIPARP/ARTD14) catalytic activity. Biochemical Journal 2018 ;Volume 475.(23) p. 3827-3846
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8 Sæther, Thomas; Paulsen, Steinar M; Tungen, Jørn Eivind; Vik, Anders; Aursnes, Marius; Holen, Torgeir; Hansen, Trond Vidar; Nebb, Hilde Irene.
Synthesis and biological evaluations of marine oxohexadecenoic acids: PPARα/γ dual agonism and anti-diabetic target gene effects. European Journal of Medicinal Chemistry 2018 ;Volume 155. p. 736-753
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2017
9 Fan, Qiong; Nørgaard, Rikke Christine; Bindesbøll, Christian; Lucas, Christin; Dalen, Knut Tomas; Babaie, Eshrat; Itkonen, Harri; Matthews, Jason; Nebb, Hilde Irene; Grønning-Wang, Line Mariann.
LXR? regulates hepatic ChREBP? activity and lipogenesis upon glucose, but not fructose feeding in mice. Nutrients 2017 ;Volume 9.(7)
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10 Haj Yasein, Nadia; Berg, Ole; Jerneren, Fredrik; Refsum, Helga; Nebb, Hilde Irene; Dalen, Knut Tomas.
Cysteine deprivation prevents induction of peroxisome proliferator-activated receptor gamma-2 and adipose differentiation of 3T3-L1 cells. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 2017 ;Volume 1862.(6) p. 623-635
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11 Moldes-Anaya, Angel; Sæther, Thomas; Uhlig, Silvio; Nebb, Hilde Irene; Larsen, Terje; Eilertsen, Hans Christian; Paulsen, Steinar Martin.
Two Isomeric C16 Oxo-Fatty Acids from the Diatom Chaetoceros karianus Show Dual Agonist Activity towards Human Peroxisome Proliferator-Activated Receptors (PPARs) α/γ. Marine Drugs 2017 ;Volume 15.(148) p. -
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12 Nørgaard, Rikke Christine; Fan, Qiong; Lucas, Christin; Grønning-Wang, Line Mariann; Nebb, Hilde Irene; Sæther, Thomas.
LXRα interacts with the glucose-sensing transcription factor ChREBPα and increases its transcriptional activity. Throne Holst Symposium; 2017-05-18 - 2017-05-18
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2016
13 Bindesbøll, Christian; Tan, Susanna; Bott, Debbie; Cho, Tiffany; Tamblyn, Laura; MacPherson, Laura; Grønning-Wang, Line Mariann; Nebb, Hilde Irene; Matthews, Jason.
TCDD-inducible poly-ADP-ribose polymerase (TIPARP/PARP7) mono-ADP-ribosylates and co-activates liver X receptors. Biochemical Journal 2016 ;Volume 473.(7) p. 899-910
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14 Drevinge, Christina; Dalen, Knut Tomas; Mannila, Maria Nastase; Täng, Margareta Scharin; Ståhlman, Marcus; Klevstig, Martina; Lundqvist, Annika; Mardani, Ismena; Haugen, Fred; Fogelstrand, Per; Adiels, Martin; Asin-Cayuela, Jorge; Ekestam, Charlotte; Gådin, Jesper R; Lee, Yun K; Nebb, Hilde Irene; Svedlund, Sara; Johansson, Bengt R; Hulten, Lillemor Mattsson; Romeo, Stefano; Redfors, Björn; Omerovic, Elmir; Levin, Max; Gan, Li; Eriksson, Per; Andersson, Linda; Ehrenborg, Ewa; Kimmel, Alan R; Boren, Jan; Levin, M.
Perilipin 5 is protective in the ischemic heart. International Journal of Cardiology 2016 ;Volume 219. p. 446-454
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15 Sæther, Thomas; Moldes-Anaya, Angel; Tungen, Jørn Eivind; Vik, Anders; Paulsen, Steinar M; Sylte, Ingebrigt; Hansen, Trond Vidar; Nebb, Hilde Irene.
Anti-diabetic activity from marine lipids: new anti-diabetic drugs. Throne Holst Symposium; 2016-05-19 - 2016-05-19
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2015
16 Bindesbøll, Christian; Fan, Qiong; Nørgaard, Rikke Christine; MacPherson, Laura; Ruan, Hai-Bin; Wu, Jing; Pedersen, Thomas Å; Steffensen, Knut R.; Yang, Xiaoyong; Matthews, Jason; Mandrup, Susanne; Nebb, Hilde Irene; Grønning-Wang, Line Mariann.
Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity[S. Journal of Lipid Research 2015 ;Volume 56. p. 771-785
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17 Bindesbøll, Christian; Tan, Susanna; MacPherson, Laura; Moen, Anders; Anonsen, Jan Haug; Grønning-Wang, Line Mariann; Nebb, Hilde Irene; Matthews, Jason.
TIPARP MONO-ADP-RIBOSYLATES & INCREASES LIVER X RECEPTOR TRANSACTIVATION. EMBO Conference on Nuclear receptors: From molecules to humans; 2015-09-24 - 2015-09-28
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18 Sæther, Thomas; Moldes-Anaya, Angel; Tungen, Jørn Eivind; Vik, Anders; Paulsen, Steinar Martin; Sylte, Ingebrigt; Hansen, Trond Vidar; Nebb, Hilde Irene.
Anti-diabetic activity from marine lipids: new anti-diabetic drugs. EMBO Conference on Nuclear Receptors; 2015-09-24 - 2015-09-28
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2014
19 Bindesbøll, Christian; Berg, Ole; Arntsen, Borghild M; Nebb, Hilde Irene; Dalen, Knut Tomas.
Fatty acids regulate perilipin5 in muscle by activating PPARdelta. Throne Holst festaften; 2014-06-10 - 2014-06-10
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20 Dalen, Knut Tomas; Haj-Yasein, Nadia Nabil; Berg, Ole; Refsum, Helga; Nebb, Hilde Irene.
Cysteine and adipocyte differentiation. Cysteine-Obesity meeting; 2014-04-03 - 2014-04-05
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21 Halvorsen, Bente; Holm, Sverre; Yndestad, Arne; Scholz, Hanne; Sagen, Ellen Lund; Nebb, Hilde Irene; Holven, Kirsten Bjørklund; Dahl, Tuva Børresdatter; Aukrust, Pål.
Interleukin-10 increases reverse cholesterol transport in macrophages through its bidirectional interaction with liver X receptor α. Biochemical and Biophysical Research Communications - BBRC 2014 ;Volume 450.(4) p. 1525-1530
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22 Sæther, Thomas; Moldes-Anaya, Angel; Norrheim-Larsen, Laila; Larsen, Terje; Paulsen, Steinar M; Nebb, Hilde Irene.
Two near identical oxylipins from the diatom Chaetoceros karianus show isoform-specific agonist activity towards human peroxisome proliferator-activated receptors (PPARs). Throne Holst Symposium; 2014-06-10 - 2014-06-10
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2013
23 Bindesbøll, Christian; Berg, Ole; Arntsen, Borghild M; Nebb, Hilde Irene; Dalen, Knut Tomas.
Fatty acids regulate perilipin5 in muscle by activating PPARdelta. Journal of Lipid Research 2013 ;Volume 54.(7) p. 1949-1963
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24 Bindesbøll, Christian; Fan, Qiong; Sæther, Thomas; Dalen, Knut Tomas; Nebb, Hilde Irene; Grønning-Wang, Line Mariann.
Nuclear receptors as targets for treatment and prevention of metabolic diseases. 49th NBS Contact Meeting; 2013-01-31 - 2013-02-03
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25 Grønning-Wang, Line Mariann; Bindesbøll, Christian; Nebb, Hilde Irene.
The role of liver X receptor in hepatic de novo lipogenesis and cross-talk with insulin and glucose signaling. I: Lipid metabolism. IntechOpen 2013 ISBN 978-953-51-0944-0. p. 61-90
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26 Haj-Yasein, Nadia Nabil; Dalen, Knut Tomas; Berg, Ole; Bastani, Nasser Ezzatkhah; Refsum, Helga; Nebb, Hilde Irene.
Low Cysteine Interferes With PPARγ Activity And Reduces Adipocyte Differentiation. Journal of Inherited Metabolic Disease 2013 ;Volume 36. Suppl. 1 p. S44-
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27 Lei, Peng; Baysa, Anton; Nebb, Hilde Irene; Valen, Guro; Skomedal, Tor; Osnes, Jan-Bjørn; Yang, Zaiqing; Haugen, Fred.
Activation of liver X receptors in the heart leads to accumulation of intracellular lipids and attenuation of ischemia-reperfusion injury. Basic Research in Cardiology 2013 ;Volume 108. p. -
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28 Moldes-Anaya, Angel; Sæther, Thomas; Larsen, Laila Norrheim; Larsen, Terje; Nebb, Hilde Irene; Paulsen, Steinar.
Identifying natural products with agonist activity against human nuclear receptors in extracts of cultured marine microalgae. BIOPROSP_2013; 2013-02-20 - 2013-02-22
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29 Moldes-Anaya, Angel; Sæther, Thomas; Norrheim-Larsen, Laila; Nebb, Hilde Irene; Larsen, Terje; Paulsen, Steinar.
Identifying natural products with agonist or modulatory activity against human nuclear receptors in extracts from cultured marine microalgae. 14th. International Symposium on Marine Natural Products and 8th. European Conference on Marine Natural Products (MANAPRO); 2013-09-15
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30 Sæther, Thomas; Moldes-Anaya, Angel; Larsen, Laila Norrheim; Larsen, Terje; Paulsen, Steinar; Nebb, Hilde Irene.
Identifying natural products with agonist activity against human nuclear receptors in extracts of cultured marine microalgae. Keystone Symposia - Nuclear Receptors and Friends: Roles in Energy Homeostasis and Metabolic Dysfunction; 2013-04-03 - 2013-04-08
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31 Sæther, Thomas; Moldes-Anaya, Angel; Norrheim-Larsen, Laila; Larsen, Terje; Paulsen, Steinar M; Nebb, Hilde Irene.
Identifying natural products with agonist activity against human nuclear receptors in extracts of cultured marine microalgae. Throne Holst Symposium; 2013-05-06 - 2013-05-06
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2012
32 Boergesen, Michael; Pedersen, Thomas Åskov; Gross, Barbara; van Heeringen, Simon J.; Hagenbeek, Dik; Bindesbøll, Christian; Caron, Sandrine; Lalloyer, Fanny; Steffensen, Knut R.; Nebb, Hilde Irene; Gustafsson, Jan Åke; Stunnenberg, Handrik G.; Staels, Bart; Mandrup, Susanne.
Genome-Wide Profiling of Liver X Receptor, Retinoid X Receptor, and Peroxisome Proliferator-Activated Receptor alpha in Mouse Liver Reveals Extensive Sharing of Binding Sites. Molecular and Cellular Biology 2012 ;Volume 32.(4) p. 852-867
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2011
33 Boergesen, M; Pedersen, T. A.; Gross, B; van Heeringen, S. J.; Hagenbeek, D; Bindesbøll, Christian; Caron, S; Lalloyer, F; Steffensen, KR; Nebb, Hilde Irene; Gustafsson, J. A.; Stunnenberg, HG; Staels, B; Mandrup, S.
Genome-wide profiling of LXR, RXR and PPARα in mouse liver reveals extensive sharing of binding sites. Molecular and Cellular Biology 2011
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34 Holter Anthonisen, Elin; Berven, Lise; Holm, Sverre; Nygård, Maria; Grønning-Wang, Line Mariann; Nebb, Hilde Irene.
Nutritional Regulation of LXR Activity in Lipid and Glucose Metabolism. Direktør Throne Holst Stiftelsen for Ernæringsforskning Seminar; 2011-05-03 - 2011-05-03
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35 Wang, Yun Yong; Ryg, Una; Dahle, Maria Krudtaa; Steffensen, Knut Rune; Thiemermann, Christoph; Chaudry, Irshad H.; Reinholt, Finn P.; Collins, Jon L.; Nebb, Hilde Irene; Aasen, Ansgar Oddne; Gustafsson, Jan-Åke; Wang, Jacob Edward.
Liver X Receptor Protects against Liver Injury in Sepsis Caused by Rodent Cecal Ligation and Puncture. Surgical Infections 2011 ;Volume 12.(4) p. 283-289
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2010
36 Anthonisen, Elin Holter; Berven, Lise; Holm, Sverre; Nygard, M; Nygård, Maria Torvund; Nebb, Hilde Irene; Grønning-Wang, Line Mariann.
Nuclear Receptor Liver X Receptor Is O-GlcNAc-modified in Response to Glucose. Journal of Biological Chemistry 2010 ;Volume 285.(3) p. 1607-1615
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37 Anthonisen, Elin Holter; Bindesbøll, Christian; Grønning-Wang, Line Mariann; Nebb, Hilde Irene.
Glycosylation of Liver X Receptor - How Does it Influence LXR Activity?. EU-consortium: Crescendo 4th Annual Meeting; 2010-05-26 - 2010-05-28
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38 Bindesbøll, Christian; Anhonisen, Elin Holter; Mandrup, Susanne; Nebb, Hilde Irene.
Selective regulation of LXR metabolic pathways by SIRT1. EU annual meeting; 2010-05-26 - 2010-05-29
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39 Dahl, Tuva Børresdatter; Haukeland, John Willy; Yndestad, Arne; Ranheim, Trine; Gladhaug, Ivar Prydz; Damås, Jan Kristian; Haaland, Therese Kristina; Løberg, Else Marit; Arntsen, Borghild M; Birkeland, Kåre I.; Bjøro, Kristian; Ulven, Stine Marie; Zbigniew, Konopski; Nebb, Hilde Irene; Aukrust, Pål; Halvorsen, Bente.
Intracellular Nicotinamide Phosphoribosyltransferase Protects against Hepatocyte Apoptosis and Is Down-Regulated in Nonalcoholic Fatty Liver Disease. Journal of Clinical Endocrinology and Metabolism 2010 ;Volume 95.(6) p. 3039-3047
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40 Holm, Sverre; Voshol, Peter; Gustafsson, Jan Åke; Nebb, Hilde Irene.
LXR beta deficient mice have reduced hepatic insulin clearance during hyperinsulinemic euglucemic clamp. Biochemical and Biophysical Research Communications - BBRC 2010 ;Volume 392.(3) p. 436-441
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41 Nebb, Hilde Irene.
Cysteine and obesity: Searching for cellular mechanism(s). Workshop; 2010-01-25 - 2010-01-27
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42 Nebb, Hilde Irene.
On the role of LXRs in glucose and lipid metabolism. Foredrag; 2010-11-25 - 2010-11-25
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43 Nebb, Hilde Irene.
Realfagenes betydning for basalforskning innen medisin. Nasjonalt forum for realfag; 2010-06-08
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44 Nebb, Hilde Irene.
Teknologi- og servicesentre for bedrifter som forsker. TEKNA; 2010-09-08
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45 Solaas, Karianne; Legry, Vanessa; Retterstøl, Kjetil; Berg, Paul Ragnar; Holven, Kirsten Bjørklund; Ferrieres, Jean; Amouyel, Philippe; Lien, Sigbjørn; Romeo, Javier; Valtuena, Jara; Widhalm, Kurt; Ruiz, Jonatan; Dallongeville, Jean; Tonstad, Serena; Rootwelt, Helge; Halvorsen, Bente; Nenseter, Marit Sofie; Birkeland, Kåre I.; Thorsby, Per Medbøe; Meirhaeghe, Aline; Nebb, Hilde Irene.
Suggestive evidence of associations between liver X receptor beta polymorphisms with type 2 diabetes mellitus and obesity in three cohort studies: HUNT2 (Norway), MONICA (France) and HELENA (Europe). BMC Medical Genetics 2010 ;Volume 11.(144) p. -
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46 Solaas, Karianne; Legry, Vanessa; Retterstøl, Kjetil; Birkeland, Kåre I.; Meirhaeghe, Aline; Nebb, Hilde Irene.
Liver X receptor β polymorphisms in type 2 diabetes mellitus and obesity in three cohort studies: HUNT 2 (Norway), MONICA (France) and HELENA (Europe). Eu-annual meeting; 2010-05-26 - 2010-05-29
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47 Weedon, Mina Susanne; Dalen, Knut Tomas; Solaas, Karianne; Staff, Anne Cathrine; Duttaroy, Asim K.; Nebb, Hilde Irene.
Activation of LXR increases acyl-CoA synthetase activity through direct regulation of ACSL3 in human placental trophoblast cells. Journal of Lipid Research 2010 ;Volume 51.(7) p. 1886-1896
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48 Weedon-Fekjær, Mina Susanne; Johnsen, Guro Mørk; Anthonisen, Elin Holter; Sugulle, Meryam; Nebb, Hilde Irene; Duttaroy, Asim K.; Staff, Anne Cathrine.
Expression of Liver X Receptors in Pregnancies Complicated by Preeclampsia. Placenta 2010 ;Volume 31.(9) p. 818-824
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2009
49 Solaas, Karianne; Legry, Vanesssa; Holven, Kirsten Bjørklund; Retterstøl, Kjetil; Thorsby, Per Medbøe; Ferrieres, J; Tonstad, Serena; Lien, Sigbjørn; Halvorsen, Bente; Nenseter, Marit Sofie; Amouyel, P; Meirhaeghe, Aline; Nebb, Hilde Irene.
Association study between LXRbeta polymorphisms and type 2 diabetes mellitus. The European association for the study of Diabetes (EASD) 45th Annual Meeting; 2009-09-29 - 2009-10-01
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50 Anthonisen, Elin Holter; Grønning-Wang, Line Mariann; Berven, Lise; Holm, Sverre; Nygård, Maria; Nebb, Hilde Irene.
The Nuclear Receptor LXR is O-GlcNAc Modified in Response to Glucose. EMBO Conference on Nuclear Receptors; 2009-09-25 - 2009-09-29
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