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Showing results 1-22 of 22

2021
1 Davydova, Erna; Shimazu, Tadahiro; Schuhmacher, Maren Kirstin; Jakobsson, Magnus E.; Willemen, Hanneke L.D.M.; Liu, Tongri; Moen, Anders; Ho, Angela Yeuan Yen; Malecki, Jedrzej Mieczyslaw; Schroer, Lisa; Pinto, Rita; Suzuki, Takehiro; Grønsberg, Ida A.; Sohtome, Yoshihiro; Akakabe, Mai; Weirich, Sara; Kikuchi, Masaki; Olsen, Jesper V.; Dohmae, Naoshi; Umehara, Takashi; Sodeoka, Mikiko; Siino, Valentina; McDonough, Michael A.; Eijkelkamp, Niels; Schofield, Christopher J.; Jeltsch, Albert; Shinkai, Yoichi; Falnes, Pål Øystein.
The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes. Nature Communications 2021 ;Volume 12:891. p. 1-14
UiO Untitled
 
2 Malecka, Agnieszka Maria; Trøen, Gunhild; Delabie, Jan; Malecki, Jedrzej Mieczyslaw; Østlie, Ingunn; Tierens, Anne; Randen, Ulla; Berentsen, Sigbjørn; Tjønnfjord, Geir Erland.
The mutational landscape of cold agglutinin disease: CARD11 and CXCR4 mutations are correlated with lower hemoglobin levels. American Journal of Hematology 2021 p. -
AHUS HELSEFONNA OUS UiO Untitled
 
2019
3 Malecki, Jedrzej Mieczyslaw; Willemen, Hanneke L.D.M.; Pinto, Rita; Ho, Angela Yeuan Yen; Moen, Anders; Eijkelkamp, Niels; Falnes, Pål Øystein.
Human FAM173A is a mitochondrial lysine-specific methyltransferase that targets adenine nucleotide translocase and affects mitochondrial respiration. Journal of Biological Chemistry 2019 ;Volume 294.(31) p. 11654-11664
UiO Untitled
 
4 Pinto, Rita; Vågbø, Cathrine Broberg; Jakobsson, Magnus; Yeji, Kim; Baltissen, Marijke P; O'Donohue, Marie-Francoise; Guzman, Ulises H; Malecki, Jedrzej Mieczyslaw; Wu, Jie; Kirpekar, Finn; Olsen, Jesper V; Gleizes, Pierre-Emmanuel; Vermeulen, Michiel; Leidel, Sebastian A.; Slupphaug, Geir; Falnes, Pål Øystein.
The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA. Nucleic Acids Research (NAR) 2019 ;Volume 48.(2) p. 830-846
NTNU STO UiO Untitled
 
2018
5 Jakobsson, Magnus; Malecki, Jedrzej Mieczyslaw; Falnes, Pål Øystein.
Regulation of eukaryotic elongation factor 1 alpha (eEF1A) by dynamic lysine methylation. RNA Biology 2018 ;Volume 15.(3) p. 314-319
UiO Untitled
 
6 Jakobsson, Magnus; Malecki, Jedrzej Mieczyslaw; Halabelian, Levon; Nilges, Benedikt S.; Pinto, Rita; Kudithipudi, Srikanth; Munk, Stephanie; Davydova, Erna; Zuhairi, Fawsi Rahmadiyan; Arrowsmith, Cheryl H; Jeltsch, Albert; Leidel, Sebastian A.; Olsen, Jesper V.; Falnes, Pål Øystein.
The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates. Nature Communications 2018 ;Volume 9:3411. p. 1-15
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7 Malecki, Jedrzej Mieczyslaw; Willemen, Hanneke L.D.M.; Pinto, Rita; Ho, Angela Yeuan Yen; Moen, Anders; Kjønstad, Ingrid Fadum; Burgering, Boudewijn M.T.; Zwartkruis, Fried; Eijkelkamp, Niels; Falnes, Pål Øystein.
Lysine methylation by the mitochondrial methyltransferase FAM173B optimizes the function of mitochondrial ATP synthase. Journal of Biological Chemistry 2018 ;Volume 294.(4) p. 1128-1141
UiO Untitled
 
8 Willemen, Hanneke L.D.M.; Kavelaars, Annemieke; Prado, Judith; Maas, MIrjam; Versteeg, Sabine; Nellissen, Lara J.J.; Tromp, Jeshua; Gonzalez Cano, Rafael; Zhou, Wenjun; Jakobsson, Magnus; Malecki, Jedrzej Mieczyslaw; Posthuma, George; Habib, Abdella; Heijnen, Cobi J.; Falnes, Pål Øystein; Eijkelkamp, Niels.
Identification of FAM173B as a protein methyltransferase promoting chronic pain. PLoS Biology 2018 ;Volume 16.(2) p. -
UiO Untitled
 
2017
9 Jakobsson, Magnus; Malecki, Jedrzej Mieczyslaw; Nilges, Benedikt S.; Moen, Anders; Leidel, Sebastian A.; Falnes, Pål.
Methylation of human eukaryotic elongation factor alpha (eEF1A) by a member of a novel protein lysine methyltransferase family modulates mRNA translation. Nucleic Acids Research (NAR) 2017 ;Volume 45. p. 8239-8254
UiO Untitled
 
10 Malecka, Agnieszka Maria; Trøen, Gunhild; Tierens, Anne; Østlie, Ingunn; Malecki, Jedrzej Mieczyslaw; Randen, Ulla; Wang, Junbai; Berentsen, Sigbjørn; Tjønnfjord, Geir Erland; Delabie, Jan.
Frequent somatic mutations of KMT2D (MLL2) and CARD11 genes in primary cold agglutinin disease.. British Journal of Haematology 2017 ;Volume 183.(5) p. 838-842
HELSEFONNA OUS UiO Untitled
 
11 Malecki, Jedrzej Mieczyslaw; Aileni, Vinay Kumar; Ho, Angela Yeuan Yen; Schwarz, Juliane; Moen, Anders; Sørensen, Vigdis; Nilges, Benedikt S.; Jakobsson, Magnus; Leidel, Sebastian A.; Falnes, Pål.
The novel lysine specific methyltransferase METTL21B affects mRNA translation through inducible and dynamic methylation of Lys-165 in human eukaryotic elongation factor 1 alpha (eEF1A). Nucleic Acids Research (NAR) 2017 ;Volume 45.(8) p. 4370-4389
OUS UiO Untitled
 
12 Malecki, Jedrzej Mieczyslaw; Jakobsson, Magnus; Ho, Angela Yeuan Yen; Moen, Anders; Rustan, Arild; Falnes, Pål.
Uncovering human METTL12 as a mitochondrial methyltransferase that modulates citrate synthase activity through metabolite-sensitive lysine methylation. Journal of Biological Chemistry 2017 ;Volume 292.(43) p. 17950-17962
UiO Untitled
 
2016
13 Falnes, Pål; Jakobsson, Magnus; Davydova, Erna; Ho, Angela Yeuan Yen; Malecki, Jedrzej Mieczyslaw.
Protein lysine methylation by seven-β-strand methyltransferases. Biochemical Journal 2016 ;Volume 473.(14) p. 1995-2009
UiO Untitled
 
14 Malecka, Agnieszka Maria; Trøen, Gunhild; Tierens, Anne; Østlie, Ingunn; Malecki, Jedrzej Mieczyslaw; Randen, Ulla; Berentsen, Sigbjørn; Tjønnfjord, Geir Erland; Delabie, Jan M.A..
Immunoglobulin heavy and light chain gene features are correlated with primary cold agglutinin disease onset and activity. Haematologica 2016 ;Volume 101.(9) p. e361-e364
HELSEFONNA OUS UiO Untitled
 
15 Malecki, Jedrzej Mieczyslaw; Dahl, Helge-Andre; Moen, Anders; Davydova, Erna; Falnes, Pål.
The METTL20 homologue from agrobacterium tumefaciens is a dual specificity protein-lysine methyltransferase that targets ribosomal protein L7/L12 and the β subunit of electron transfer flavoprotein (ETFβ). Journal of Biological Chemistry 2016 ;Volume 291.(18) p. 9581-9595
UiO Untitled
 
2015
16 Jakobsson, Magnus; Davydova, Erna; Malecki, Jedrzej Mieczyslaw; Moen, Anders; Falnes, Pål.
Saccharomyces cerevisiae eukaryotic elongation factor 1A (eEF1A) is methylated at Lys-390 by a METTL21-like methyltransferase. PLOS ONE 2015 ;Volume 10.(6)
UiO Untitled
 
17 Malecki, Jedrzej Mieczyslaw; Ho, Angela Yeuan Yen; Moen, Anders; Dahl, Helge-Andre; Falnes, Pål.
Human METTL20 is a mitochondrial lysine methyltransferase that targets the β subunit of electron transfer flavoprotein (ETFβ) and modulates its activity. Journal of Biological Chemistry 2015 ;Volume 290.(1) p. 423-434
UiO Untitled
 
2014
18 Davydova, Erna; Ho, Angela Yeuan Yen; Malecki, Jedrzej Mieczyslaw; Moen, Anders; Enserink, Jorrit; Jakobsson, Magnus; Loenarz, Christoph; Falnes, Pål.
Identification and characterization of a novel evolutionarily conserved lysine-specific methyltransferase targeting eukaryotic translation elongation factor 2 (eEF2). Journal of Biological Chemistry 2014 ;Volume 289.(44) p. 30499-30510
OUS UiO Untitled
 
2008
19 Haugsten, Ellen Margrethe; Malecki, Jedrzej M.; Bjørklund, Sunniva Maria Stordal; Olsnes, Sjur; Wesche, Jørgen.
Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis. Molecular Biology of the Cell 2008 ;Volume 19. p. 3390-3403
OUS UiO Untitled
 
2006
20 Wesche, Jørgen; Malecki, Jedrzej M.; Wiedlocha, Antoni; Skjerpen, Camilla Skiple; Claus, P; Olsnes, Sjur.
FGF-1 and FGF-2 require the cytosolic chaperone Hsp90 for translocation into the cytosol and the cell nucleus. Journal of Biological Chemistry 2006 ;Volume 281. p. 11405-11412
UiO Untitled
 
2005
21 Wesche, Jørgen; Malecki, Jedrzej M.; Wiedlocha, Antoni; Ehsani, Maryam; Nilsen, Trine; Marcinkowska, Ewa; Olsnes, Sjur.
Two nuclear localization signals required for transport from the cytosol to the, nucleus of externally added FGF-1 translocated into cells. Biochemistry (Moscow) 2005 ;Volume 44.
UiO Untitled
 
2002
22 Malecki, Jedrzej M.; Wiedlocha, Antoni; Wesche, Jarlis; Olsnes, Sjur.
Vesicle transmembrane potential is required for translocation to cytosol externally added FGF-1. EMBO Journal 2002 ;Volume 21. p. 4480-4490
UiO Untitled