Current Research Information SysTem In Norway
 
 

 Norsk versjon


 
Mainpage
Research results/NVI
Researchers
Projects
Research units
Log in
About Cristin
 
 
   
Back to search     Short format     Full format    
Export to


Showing results 1-50 of 186 << Previous 1 2 3 4    Next >>

2019
1 Melsom, Elin Maria Caroline Bull; Cosson, Marie-Victoire; Ørstavik, Øivind; Lai, Ngai Chin; Hammond, H. Kirk; Osnes, Jan-Bjørn; Skomedal, Tor; Nikolaev, Viacheslav; Levy, Finn Olav; Krobert, Kurt Allen.
Constitutive inhibitory G protein activity upon adenylyl cyclase-dependent cardiac contractility is limited to adenylyl cyclase type 6. PLOS ONE 2019 ;Volume 14:e021810.(6) p. 1-19
OUS UiO Untitled
 
2017
2 Meier, Silja; Andressen, Kjetil Wessel; Aronsen, Jan Magnus; Sjaastad, Ivar; Hougen, Karina; Skomedal, Tor; Osnes, Jan-Bjørn; Qvigstad, Eirik; Levy, Finn Olav; Moltzau, Lise Roman.
PDE3 inhibition by C-type natriuretic peptide-induced cGMP enhances cAMP-mediated signaling in both non-failing and failing hearts. European Journal of Pharmacology 2017 ;Volume 812. p. 174-183
BJORKNES OUS UiO Untitled
 
2016
3 Eikemo, Hilde; Moltzau, Lise Roman; Hussain, Rizwan; Nguyen, Hong Cam Thi; Qvigstad, Eirik; Skomedal, Tor; Osnes, Jan-Bjørn; Levy, Finn Olav.
CaMKII in addition to MLCK contributes to phosphorylation of regulatory light chain in cardiomyocytes. Biochemical and Biophysical Research Communications - BBRC 2016 ;Volume 471.(1) p. 219-225
OUS UiO Untitled
 
4 Eikemo, Hilde; Moltzau, Lise Roman; Nguyen, Hong Cam Thi; Levy, Finn Olav; Skomedal, Tor; Osnes, Jan-Bjørn.
CaMKII and at least two unidentified kinases phosphorylate regulatory light chain in non-contracting cardiomyocytes. Biochemical and Biophysical Research Communications - BBRC 2016 ;Volume 477.(1) p. 14-19
OUS UiO Untitled
 
2015
5 Meier, Silja; Andressen, Kjetil Wessel; Aronsen, Jan Magnus; Sjaastad, Ivar; Skomedal, Tor; Osnes, Jan-Bjørn; Qvigstad, Eirik; Levy, Finn Olav; Moltzau, Lise Roman.
Enhancement of cAMP-mediated inotropic responses by CNP is regulated differently by PDE2 in normal and failing hearts. BMC Pharmacology & Toxicology 2015 ;Volume 16. Suppl. 1 p. A66-A66
UiO Untitled
 
6 Ørstavik, Øivind; Manfra, Ornella; Andressen, Kjetil Wessel; Andersen, Geir Øystein; Skomedal, Tor; Osnes, Jan-Bjørn; Levy, Finn Olav; Krobert, Kurt Allen.
The inotropic effect of the active metabolite of levosimendan, OR-1896, is mediated through inhibition of PDE3 in rat ventricular myocardium. PLOS ONE 2015 ;Volume 10.(3)
OUS UiO Untitled
 
2014
7 Bach, Trond; Bergholtz, Stine Louise; Riise, Jon; Qvigstad, Eirik; Skomedal, Tor; Osnes, Jan-Bjørn; Levy, Finn Olav.
Identification of small molecule NPR-B antagonists by high throughput screening - potential use in heart failure. Naunyn-Schmiedeberg's Archives of Pharmacology 2014 ;Volume 387.(1) p. 5-14
OUS UiO Untitled
 
8 Meier, Silja; Moltzau, Lise Roman; Aronsen, Jan Magnus; Sjaastad, Ivar; Skomedal, Tor; Osnes, Jan-Bjørn; Qvigstad, Eric; Levy, Finn Olav.
Enhancement of B1 - adrenoceptor signaling by CNP through NPR-B and regulation by phosphodiesterases in normal and failing hearts. 12th Annual Symposium Center for Heart Failure Research on Heart Failure; 2014-09-17 - 2014-09-19
OUS UiO Untitled
 
9 Melsom, Elin Maria Caroline Bull; Hussain, Rizwan; Ørstavik, Øivind; Aronsen, Jan Magnus; Sjaastad, Ivar; Skomedal, Tor; Osnes, Jan-Bjørn; Levy, Finn Olav; Krobert, Kurt Allen.
Non-classical regulation of β1- and β2 adrenoceptor- mediated inotropic responses in rat ventricle by the G protein Gi. Naunyn-Schmiedeberg's Archives of Pharmacology 2014 ;Volume 387.(12) p. 1177-1186
BJORKNES OUS UiO Untitled
 
10 Melsom, Elin Maria Caroline Bull; Ørstavik, Øivind; Osnes, Jan-Bjørn; Skomedal, Tor; Levy, Finn Olav; Krobert, Kurt Allen.
Gi proteins regulate adenylyl cyclase activity independent of receptor activation. PLoS Medicine 2014 ;Volume 9:e0106608.(9)
OUS UiO Untitled
 
11 Moltzau, Lise Roman; Aronsen, Jan Magnus; Meier, Silja; Skogestad, Jonas; Ørstavik, Øivind; Lothe, Gustav B; Sjaastad, Ivar; Skomedal, Tor; Osnes, Jan-Bjørn; Levy, Finn Olav; Qvigstad, Eirik.
Different compartmentation of responses to brain natriuretic peptide and C-type natriuretic peptide in failing rat ventricle. Journal of Pharmacology and Experimental Therapeutics 2014
BJORKNES OUS UiO Untitled
 
12 Moltzau, Lise Roman; Meier, Silja; Aronsen, Jan Magnus; Afzal, Faraz; Sjaastad, Ivar; Skomedal, Tor; Osnes, Jan-Bjørn; Levy, Finn Olav; Qvigstad, Eirik.
Differential regulation of C-type natriuretic peptide-induced cGMP and functional responses by PDE2 and PDE3 in failing myocardium. Naunyn-Schmiedeberg's Archives of Pharmacology 2014 ;Volume 387.(5) p. 407-417
BJORKNES OUS UiO Untitled
 
13 Ørstavik, Øivind; Ata, Salmana H; Riise, Jon; Dahl, Christen Peder; Andersen, Geir Øystein; Levy, Finn Olav; Skomedal, Tor; Osnes, Jan-Bjørn; Qvigstad, Eirik.
Inhibition of phosphodiesterase-3 by levosimendan is sufficient to account for its inotropic effect in failing human heart. British Journal of Pharmacology 2014 ;Volume 171.(23) p. 5169-5181
OUS UiO Untitled
 
2013
14 Gravning, Jørgen A.; Ahmed, Muhammad Shakil; Qvigstad, Eirik; Krobert, Kurt Allen; Edvardsen, Thor; Moe, Ingvild Tronstad; Hagelin, Else Marie Valbjørn; Sagave, Julia Fritzi; Valen, Guro; Levy, Finn Olav; Osnes, Jan-Bjørn; Skomedal, Tor; Attramadal, Håvard.
Connective Tissue Growth Factor/CCN2 Attenuates beta-Adrenergic Receptor Responsiveness and Cardiotoxicity by Induction of G Protein-Coupled Receptor Kinase-5 in Cardiomyocytes. Molecular Pharmacology 2013 ;Volume 84.(3) p. 372-383
OUS UiO Untitled
 
15 Hussain, Rizwan; Aronsen, Jan Magnus; Afzal, Faraz; Sjaastad, Ivar; Osnes, Jan-Bjørn; Skomedal, Tor; Levy, Finn Olav; Krobert, Kurt Allen.
The functional activity of inhibitory G protein (Gi) is not increased in failing heart ventricle. Journal of Molecular and Cellular Cardiology 2013 ;Volume 56. p. 129-138
BJORKNES OUS UiO Untitled
 
16 Lei, Peng; Baysa, Anton; Nebb, Hilde Irene; Valen, Guro; Skomedal, Tor; Osnes, Jan-Bjørn; Yang, Zaiqing; Haugen, Fred.
Activation of liver X receptors in the heart leads to accumulation of intracellular lipids and attenuation of ischemia-reperfusion injury. Basic Research in Cardiology 2013 ;Volume 108. p. -
OUS UiO Untitled
 
17 Moltzau, Lise Roman; Aronsen, Jan Magnus; Meier, Silja; Nguyen, Hong Cam Thi; Hougen, Karina; Ørstavik, Øivind; Sjaastad, Ivar; Christensen, Geir Arve; Skomedal, Tor; Osnes, Jan-Bjørn; Levy, Finn Olav; Qvigstad, Eirik.
SERCA2 activity is involved in the CNP-mediated functional responses in failing rat myocardium. British Journal of Pharmacology 2013 ;Volume 170.(2) p. 366-379
BJORKNES OUS UiO Untitled
 
2012
18 Brattelid, Trond; Qvigstad, Eirik; Moltzau, Lise Roman; Bekkevold, Silje Veslemøy; Sandnes, Dagny Lise; Birkeland, Jon Arne; Skomedal, Tor; Osnes, Jan-Bjørn; Sjaastad, Ivar; Levy, Finn Olav.
The Cardiac Ventricular 5-HT4 Receptor Is Functional in Late Foetal Development and Is Reactivated in Heart Failure. PLOS ONE 2012 ;Volume 7.(9)
HAVFORSK OUS UiO Untitled
 
19 Moltzau, Lise Roman; Aronsen, Jan Magnus; Meier, Silja; Sjaastad, Ivar; Skomedal, Tor; Osnes, Jan-Bjørn; Levy, Finn Olav; Qvigstad, Eirik.
NPR-A and NPR-B signal in different functional compartments in failing rat left ventricle. Cardiovascular Research (CVR) 2012 ;Volume 93. p. S18-S18
OUS UiO Untitled
 
20 Riise, Jon; Nguyen, Hong Cam Thi; Hussain, Rizwan; Dahl, Christen Peder; Ege, Maren Stapnes; Osnes, Jan-Bjørn; Skomedal, Tor; Sandnes, Dagny Lise; Levy, Finn Olav; Krobert, Kurt Allen.
Prostanoid-mediated inotropic responses are attenuated in failing human and rat ventricular myocardium. European Journal of Pharmacology 2012 ;Volume 686.(1-3) p. 66-73
OUS UiO Untitled
 
21 Riise, Jon; Ørstavik, Øivind; Qvigstad, Eirik; Dahl, Christen Peder; Osnes, Jan-Bjørn; Skomedal, Tor; Levy, Finn Olav; Krobert, Kurt Allen.
Prostaglandin E-1 facilitates inotropic effects of 5-HT4 serotonin receptors and beta-adrenoceptors in failing human heart. Basic Research in Cardiology 2012 ;Volume 107.(5) p. -
OUS UiO Untitled
 
2011
22 Afzal, Faraz; Aronsen, Jan Magnus; Moltzau, Lise Roman; Sjaastad, Ivar; Levy, Finn Olav; Skomedal, Tor; Osnes, Jan-Bjørn; Qvigstad, Eirik.
Differential regulation of beta(2)-adrenoceptor-mediated inotropic and lusitropic response by PDE3 and PDE4 in failing and non-failing rat cardiac ventricle. British Journal of Pharmacology 2011 ;Volume 162.(1) p. 54-71
OUS UiO Untitled
 
23 Afzal, Faraz; Qvigstad, Eirik; Aronsen, Jan Magnus; Moltzau, Lise Roman; Sjaastad, Ivar; Skomedal, Tor; Osnes, Jan-Bjørn; Levy, Finn Olav.
Agents increasing cyclic GMP amplify 5-HT4-elicited positive inotropic response in failing rat cardiac ventricle. Naunyn-Schmiedeberg's Archives of Pharmacology 2011 ;Volume 384.(6) p. 543-553
OUS UiO Untitled
 
24 Hussain, Rizwan; Afzal, Faraz; Mørk, Halvor Kjeang; Aronsen, Jan Magnus; Sjaastad, Ivar; Osnes, Jan-Bjørn; Skomedal, Tor; Levy, Finn Olav; Krobert, Kurt Allen.
Cyclic AMP-dependent inotropic effects are differentially regulated by muscarinic G(i)-dependent constitutive inhibition of adenylyl cyclase in failing rat ventricle. British Journal of Pharmacology 2011 ;Volume 162.(4) p. 908-916
OUS UiO Untitled
 
25 Meier, Silja; Aronsen, Jan Magnus; Sjaastad, Ivar; Levy, Finn Olav; Skomedal, Tor; Osnes, Jan-Bjørn; Qvigstad, Eirik.
Enhancement of B1-adrenoceptor signaling by C-type natriuretic peptide through natriuretic peptide receptor B in normal and failing hearts: regulation by phosphodiesterases. 9th Annual CHFR Symposium; 2011-09-15 - 2011-09-16
OUS UiO Untitled
 
26 Melsom, CB; Hussain, Rizwan; Aronsen, Jan Magnus; Sjaastad, Ivar; Osnes, Jan-Bjørn; Skomedal, Tor; Levy, Finn Olav; Krobert, Kurt Allen.
The role of inhibitory G protein upon beta-adrenoceptor-mediated signalling and inotropic responses in normal and failing rat heart left ventricle: Functional evidence of "tonic" Gi activation. 9th Annual CHFR Symposium; 2011-09-15 - 2011-09-16
OUS UiO Untitled
 
27 Moltzau, Lise Roman; Aronsen, Jan Magnus; Meier, Silja; Nguyen, Cam; Christensen, Geir Arve; Sjaastad, Ivar; Skomedal, Tor; Osnes, Jan-Bjørn; Levy, Finn Olav; Qvigstad, Eirik.
The mechanism of CNP-induced negative inotropic and positive lusitropic responses are dependent on SERCA activity in failing rat ventricle. 5th International Conference on cGMP; 2011-06-24 - 2011-06-26
BJORKNES OUS UiO Untitled
 
28 Moltzau, Lise Roman; Aronsen, Jan Magnus; Meier, Silja; Nguyen, Cam; Christensen, Geir Arve; Sjaastad, Ivar; Skomedal, Tor; Osnes, Jan-Bjørn; Levy, Finn Olav; Qvigstad, Eirik.
The negative inotropic and positive lusitropic responses to CNP are dependent on SERCA2 activity in failing rat ventricle. 9th Annual CHFR Symposium; 2011-09-15 - 2011-09-16
BJORKNES OUS UiO Untitled
 
2010
29 Meier, Silja; Aronsen, Jan Magnus; Levy, Finn Olav; Skomedal, Tor; Osnes, Jan-Bjørn; Qvigstad, Eirik.
C-type natriuretic peptide signalling through NPR-B enhances the B1-AR signalling both in non-failing and failing rat hearts. 8th Annual Center for Heart Failure Research Symposium; 2010-09-29 - 2010-10-01
UiO Untitled
 
30 Meier, Silja; Levy, Finn Olav; Skomedal, Tor; Qvigstad, Eirik; Osnes, Jan-Bjørn.
Cardiac tissue hypothyroidism and receptor functions in heart failure. NSFTs Vintermøte 2010; 2010-01-28 - 2010-01-31
UiO Untitled
 
31 Moltzau, Lise Roman; Aronsen, Jan Magnus; Meier, Silja; Nguyen, Hong Cam Thi; Afzal, Faraz; Sjaastad, Ivar; Skomedal, Tor; Osnes, Jan-Bjørn; Levy, Finn Olav; Qvigstad, Eirik.
Compartmentation of the cGMP signal causes differential functional responses after CNP and BNP stimulation in failing myocardium. 8th Annual Center for Heart Failure Research Symposium; 2010-09-29 - 2010-10-01
UiO Untitled
 
32 Qvigstad, Eirik; Afzal, Faraz; Aronsen, Jan Magnus; Moltzau, Lise Roman; Sjaastad, Ivar; Skomedal, Tor; Osnes, Jan-Bjørn; Levy, Finn Olav.
The NO/cyclic GMP signalling pathway differentially affects 5-HT4 - and B1-AR mediated inotropic responses in failing ventricle. 8th Annual Center for Heart Failure Research Symposium; 2010-09-30 - 2010-10-01
UiO Untitled
 
33 Qvigstad, Eirik; Moltzau, Lise Roman; Aronsen, Jan Magnus; Nguyen, Hong Cam Thi; Hougen, Karina; Sjaastad, Ivar; Levy, Finn Olav; Skomedal, Tor; Osnes, Jan-Bjørn.
Natriuretic peptides increase beta(1)-adrenoceptor signalling in failing hearts through phosphodiesterase 3 inhibition. Cardiovascular Research (CVR) 2010 ;Volume 85.(4) p. 763-772
OUS UiO Untitled
 
2009
34 Ansteinsson, V; Refsnes, Magne; Skomedal, T; Osnes, JB; Schiander, I; Gutowska-Schiander, Iwona; Låg, Marit.
Zinc- and copper-induced interleukin-6 release in primary cell cultures from rat heart. Cardiovascular Toxicology 2009 ;Volume 9.(2) p. 86-94
FHI NIOM UiO Untitled
 
35 Afzal, Faraz; Aronsen, Jon magnus; Moltzau, Lise Roman; Sjaastad, Ivar; Levy, Finn Olav; Skomedal, Tor; Osnes, Jan-Bjørn; Qvigstad, Eirik.
Differential regulation of b2-adrenoceptor-mediated responses by PDE3 and PDE4 in failing and non-failing rat myocardium. 7th Annual CHFR Symposium; 2009-09-24 - 2009-09-25
UiO Untitled
 
36 Aursnes, Ivar; Osnes, Jan-Bjørn.
Atenolol Versus Other Beta-Adrenergic Blockers. Journal of the American College of Cardiology 2009 ;Volume 53.(22) p. 2101-2102
UiO Untitled
 
37 Gravning, Jørgen A.; Ahmed, Muhammad Shakil; Qvigstad, Eirik; Sagave, Julia Fritzi; Krobert, Kurt Allen; Edvardsen, Thor; Valen, Guro; Skomedal, Tor; Osnes, Jan-Bjørn; Attramadal, Håvard.
CCN2/CTGF - Connective Tissue Growth Factor - Reduces beta-Adrenergic Receptor Responsiveness and Catecholamine-Induced Cardiotoxicity by Upregulation of Cardiac Myocyte G Protein-Coupled Receptor Kinase-5. Circulation 2009 ;Volume 120.(18) p. S720-S720
OUS Untitled
 
38 Hussain, RI; Qvigstad, Eirik; Birkeland, Jon Arne; Eikemo, Hilde; Glende, A; Sjaastad, Ivar; Skomedal, Tor; Osnes, Jan-Bjørn; Levy, Finn Olav; Krobert, Kurt Allen.
Activation of muscarinic receptors elicits inotropic responses in ventricular muscle from rats with heart failure through myosin light chain phosphorylation. British Journal of Pharmacology 2009 ;Volume 156.(4) p. 575-586
OUS UiO Untitled
 
39 Hussain, Rizwan; Qvigstad, Erik; Birkeland, Jon Arne; Eikemo, Hilde; Glende, A; Sjaastad, Ivar; Skomedal, Tor; Osnes, Jan-Bjørn; Levy, Finn Olav; Krobert, Kurt Allen.
Activation of muscarinic receptors elicits inotropic responses in ventricular muscle from rats with heart failure through myosin light chain phosphorylation. British Journal of Pharmacology 2009 ;Volume 156.(4) p. 575-586
OUS UiO Untitled
 
40 Kjekshus, John; Torp-Pedersen, C; Gullestad, Lars; Kober, L; Edvardsen, Thor; Olsen, IC; Sjaastad, Ivar; Qvigstad, Eirik; Skomedal, Tor; Osnes, Jan-Bjørn; Levy, Finn Olav.
Effect of piboserod, a 5-HT4 serotonin receptor antagonist, on left ventricular function in patients with symptomatic heart failure. European Journal of Heart Failure 2009 ;Volume 11.(8) p. 771-778
OUS UiO Untitled
 
41 Krobert, Kurt Allen; Hussain, Rizwan; Afzal, Faraz; Aronsen, Jon magnus; Sjaastad, Ivar; Osnes, Jan-Bjørn; Skomedal, Tor; Levy, Finn Olav.
Inreased Gi activity does not contribute to the reduced beta-adrenergic inotropic effect in failing rat ventricle but Gi acts as a tonic brake on basal adenylyl cyclase activity. 7th Annual CHFR Symposium; 2009-09-24 - 2009-09-25
UiO Untitled
 
2008
42 Afzal, Faraz; Andressen, Kjetil Wessel; Mørk, Halvor Kjeang; Aronsen, Jan Magnus; Sjaastad, Ivar; Dahl, Christen Peder; Skomedal, Tor; Levy, Finn Olav; Osnes, Jan-Bjørn; Qvigstad, Eirik.
5-HT4-elicited positive inotropic response is mediated by cAMP and regulated by PDE3 in failing rat and human cardiac ventricles. British Journal of Pharmacology 2008 ;Volume 155.(7) p. 1005-1014
OUS UiO Untitled
 
43 Eikemo, Hilde; Nguyen, Hong Cam Thi; Levy, Finn Olav; Skomedal, Tor; Osnes, Jan-Bjørn.
Evidence for an unidentified kinase activity phosphorylating myosin light chain-2 in quiescent cardiomyocytes. Journal of Molecular and Cellular Cardiology 2008 ;Volume 44. p. 782-782
UiO Untitled
 
44 Eikemo, Hilde; Skomedal, Tor; Levy, Finn Olav; Osnes, Jan-Bjørn.
Calculating reaction rate constants and estimating the efficacy of selective enzyme inhibitors. Analytical Biochemistry 2008 ;Volume 383.(2) p. 323-325
UiO Untitled
 
45 Gravning, Jørgen Amundsen; Ahmed, Muhammad Shakil; Qvigstad, Erik; Sagave, Julia Fritzi; Krobert, Kurt Allen; Edvardsen, Thor; Valen, Guro; Skomedal, Tor; Osnes, Jan-Bjørn; Attramadal, Håvard.
Connective tissue growth factor (CTGF/CCN2) desensitizes myocardial beta-adrenergic receptor signaling and inhibits isoproterenol induced hypertrophy. ESC Congress; 2008-08-30
UiO Untitled
 
46 Kjekshus, John; Edvardsen, Thor; Gullestad, Lars; Koeber, L; Osnes, Jan-Bjørn; Qvigstad, Erik; Sjaastad, Ivar; Skomedal, Tor; Torp-Pedersen, C; Levy, Finn Olav.
The effect of Piboserod a 5-HT4-receptor antagonist on left ventricular function in patients with symptomatic heart failure. Heart Failure Congress; 2008-06-17
UiO Untitled
 
47 Levy, Finn Olav; Qvigstad, Eirik; Krobert, Kurt Allen; Skomedal, Tor; Osnes, Jan-Bjørn.
Effects of serotonin in failing cardiac ventricle: Signalling mechanisms and potential therapeutic implications. Neuropharmacology 2008 ;Volume 55.(6) p. 1066-1071
UiO Untitled
 
48 Moltzau, Lise Roman; Aronsen, Jan Magnus; Nguyen, Hong Cam Thi; Sjaastad, Ivar; Afzal, Faraz; Skomedal, Tor; Osnes, Jan-Bjørn; Levy, Finn Olav; Qvigstad, Eirik.
Phospodiesterases regulating the negative inotropic response of C-type natriuretic peptide in heart failure. Fundamental & Clinical Pharmacology 2008 ;Volume 22. p. 17-17
UiO Untitled
 
49 Riise, J; Nguyen, Hong Cam Thi; Qvigstad, Eirik; Sandnes, Dagny Lise; Osnes, Jan-Bjørn; Skomedal, Tor; Levy, Finn Olav; Krobert, Kurt Allen.
Prostanoid F receptors elicit an inotropic effect in rat left ventricle by enhancing myosin light chain phosphorylation. Cardiovascular Research (CVR) 2008 ;Volume 80.(3) p. 407-415
UiO Untitled
 
50 Totlandsdal, Annike Irene; Refsnes, Magne; Skomedal, Tor; Osnes, Jan-Bjørn; Schwarze, Per E; Låg, Marit.
Particle-induced cytokine responses in cardiac cell cultures-the effect of particles versus soluble mediators released by particle-exposed lung cells. Toxicological Sciences 2008 ;Volume 106.(1) p. 233-241
FHI UiO Untitled
 
    Show next list