Cristin

2024
1.	Randsborg, Per-Henrik; Brinchmann, Jan Engelsen; Owesen, Christian; Engebretsen, Lars; Birkenes, Thomas; Hanvold, Heidi Andreassen; Saltyte Benth, Jurate; Årøen, Asbjørn. Autologous Chondrocyte Implantation Is Not Better Than Arthroscopic Debridement for the Treatment of Symptomatic Cartilage Lesions of the Knee: Two-Year Results From a Randomized-Controlled Trial. Arthroscopy, Sports Medicine, and Rehabilitation (ASMAR) 2024 ;Volume 6.(2) p. - UiO AHUS OUS NIH HAUKELAND Untitled
2023
2.	Frerker, Nadine; Karlsen, Tommy Aleksander; Stensland, Maria; Nyman, Tuula Anneli; Rayner, Simon; Brinchmann, Jan Engelsen. Comparison between articular chondrocytes and mesenchymal stromal cells for the production of articular cartilage implants. Frontiers in Bioengineering and Biotechnology 2023 ;Volume 11. p. - UiO OUS Untitled

3.	Randsborg, Per-Henrik; Brinchmann, Jan Engelsen; Owesen, Christian; Engebretsen, Lars; Birkenes, Thomas; Hanvold, Heidi Andreassen; Benth, Jūratė Šaltytėe; Årøen, Asbjørn. Bruskcelletransplantasjon vs. artroskopisk debridement av isolerte bruskskader i kneleddet. En RCT med 2 års oppfølging. Ortopedisk Høstmøte; 2023-10-25 - 2023-10-27 AHUS OUS NIH UiB UiO Untitled

4.	Årøen, Asbjørn; Brinchmann, Jan Engelsen; Engen, Cathrine N.; Randsborg, Per-Henrik; Engebretsen, Lars; Jakobsen, Rune Bruhn. The Need for Pragmatic Registry-Based Trials in Cartilage Research. Cureus 2023 p. - NIH AHUS OUS UiO Untitled
2022
5.	Brinchmann, Bendik Christian; Holme, Jørn Andreas; Frerker, Nadine; Rambøl, Mia Marie-Elisabeth; Karlsen, Tommy Aleksander; Brinchmann, Jan E.; Kubátová, Alena; Kukowski, Klara; Skuland, Tonje Schwach; Øvrevik, Johan. Effects of organic chemicals from diesel exhaust particles on adipocytes differentiated from human mesenchymal stem cells. Basic & Clinical Pharmacology & Toxicology 2022 ;Volume 132.(1) p. 83-97 FHI OUS STAMI Untitled
2021
6.	Al-Modawi, Rua Nader; Brinchmann, Jan Engelsen; Karlsen, Tommy Aleksander. Extensive downregulation of immune gene expression by microRNA-140-3p 5′ isomiR in an in vitro model of osteoarthritis. Osteoarthritis and Cartilage Open 2021 ;Volume 3.(3) p. - UiO OUS Untitled

7.	Frerker, Nadine; Karlsen, Tommy Aleksander; Lilledahl, Magnus Borstad; Brorson, Sverre Henning; Tibballs, John Earl; Brinchmann, Jan E.. Scaffold-Free Engineering of Human Cartilage Implants. Cartilage 2021 ;Volume 13.(1) p. 1237S-1249S OUS NTNU NIOM UiO Untitled
2020
8.	Aae, Tommy Frøseth; Karlsen, Tommy Aleksander; Bos-Haugen, Ida Kristin; Risberg, May Arna; Lian, Øystein Bjerkestrand; Brinchmann, Jan E.. Evaluating plasma extracellular vesicle microRNAs as possible biomarkers for osteoarthritis. Osteoarthritis and Cartilage Open 2020 ;Volume 1.(3-4) OUS NTNU UiO NIH DIAKON HMR Untitled
2019
9.	Al-Modawi, Rua Nader; Brinchmann, Jan E.; Karlsen, Tommy Aleksander. Multi-pathway protective effects of microRNAs on human chondrocytes in an in vitro model of osteoarthritis. Molecular Therapy Nucleic Acids 2019 ;Volume 17. p. 776-790 UiO OUS Untitled

10.	Idaszek, Joanna; Costantini, Marco; Karlsen, Tommy Aleksander; Jaroszewicz, Jakub; Colosi, Cristina; Testa, Stefano; Fornetti, Ersilia; Bernardini, Sergio; Seta, Martyna; Kasarello, Kaja; Wrzesien, Robert; Cannata, Stefano; Barbetta, Andrea; Gargioli, Cesare; Brinchmann, Jan E.; Swieszkowski, Wojciech. 3D bioprinting of hydrogel constructs with cell and material gradients for the regeneration of full-thickness chondral defect using a microfluidic printing head. Biofabrication 2019 ;Volume 11.(4) p. 1-15 OUS Untitled

11.	Karlsen, Tommy Aleksander; Aae, Tommy Frøseth; Brinchmann, Jan E.. Robust profiling of microRNAs and isomiRs in human plasma exosomes across 46 individuals. Scientific Reports 2019 ;Volume 9:19999. p. 1-9 HMR UiO OUS Untitled

12.	Karlsen, Tommy Aleksander; Brinchmann, Jan E.. Expression of inflammatory cytokines in mesenchymal stromal cells is sensitive to culture conditions and simple cell manipulations. Experimental Cell Research 2019 ;Volume 374.(1) p. 122-127 UiO OUS Untitled

13.	Karlsen, Tommy Aleksander; Meenakshi Sundaram, Arvind Yegambaram; Brinchmann, Jan E.. Single-Cell RNA Sequencing of In Vitro Expanded Chondrocytes: MSC-Like Cells With No Evidence of Distinct Subsets. Cartilage 2019 OUS UiO Untitled

14.	Kosik-Koziol, Alicja; Costantini, Marco; Mroz, Anna; Idaszek, Joanna; Heljak, Marcin; Jaroszewicz, Jakub; Kijenska, Ewa; Szöke, Krisztina; Frerker, Nadine; Barbetta, Andrea; Brinchmann, Jan E.; Swieszkowski, Wojciech. 3D bioprinted hydrogel model incorporating β-tricalcium phosphate for calcified cartilage tissue engineering.. Biofabrication 2019 ;Volume 11.(3) OUS UiO Untitled

15.	Suliman, Salwa; Ali, Hassan Mohamed Abdel-Raouf; Karlsen, Tommy Aleksander; Amiaud, Jérôme; Mohamed Ahmed, Samih; Layrolle, Pierre; Costea, Daniela Elena; Brinchmann, Jan E.; Mustafa, Kamal Babikeir Eln. Impact of humanised isolation and culture conditions on stemness and osteogenic potential of bone marrow derived mesenchymal stromal cells. Scientific Reports 2019 ;Volume 9. p. 1-18 UiB OUS HAUKELAND UiO Untitled

16.	Årøen, Asbjørn; Kjennvold, Stian; Brinchmann, Jan E.; Randsborg, Per-Henrik; Reinholt, Finn P.; Engebretsen, Lars. Bone marrow derived mesenchymal stem cells in a human clinical trial to repair articular cartilage defects of the knee. ICRC Summit 2019; 2019-01-17 - 2019-01-18 AHUS NIH OUS UiO Untitled
2018
17.	Brinchmann, Bendik Christian; Skuland, Tonje Schwach; Rambøl, Mia Marie-Elisabeth; Szöke, Krisztina; Brinchmann, Jan E.; Gutleb, Arno C.; Moschini, Elisa; Kubátová, Alena; Kukowski, Klara; Le Ferrec, Eric; Lagadic-Gossmann, Dominique; Schwarze, Per Everhard; Låg, Marit; Refsnes, Magne Arnold; Øvrevik, Johan; Holme, Jørn Andreas. Lipophilic components of diesel exhaust particles induce pro-inflammatory responses in human endothelial cells through AhR dependent pathway(s). Particle and Fibre Toxicology 2018 ;Volume 15. p. - OUS UiO FHI Untitled

18.	Rambøl, Mia Marie-Elisabeth; Hisdal, Jonny; Sundhagen, Jon Otto; Brinchmann, Jan E.; Rosales, Antonio. Recellularization of decellularized venous grafts using peripheral blood: a critical evaluation. EBioMedicine 2018 ;Volume 32. p. 215-222 OUS UiO Untitled

19.	Årøen, Asbjørn; Kjennvold, Stian; Brinchmann, Jan E.; Randsborg, Per-Henrik; Reinholt, Finn P.; Engebretsen, Lars. Bone marrow derived mesenchymal stem cells in a human clinical trial to repair articular cartilage defects of the knee. ICRS 2018; 2018-12-13 AHUS NIH OUS UiO Untitled
2017
20.	Behnan, Jinan; Stangeland, Biljana; Hosainey, Sayied Abdol Mohieb; Joel, Mrinal; Olsen, Thale Kristin; Micci, Francesca; Glover, Joel; Isakson, Pauline; Brinchmann, Jan E.. Differential propagation of stroma and cancer stem cells dictates tumorigenesis and multipotency. Oncogene 2017 ;Volume 36.(4) p. 570-584 STO UiO OUS Untitled

21.	Karlsen, Tommy Aleksander; Jakobsen, Rune Bruhn; Brinchmann, Jan E.. Early molecular events during in vitro chondrogenesisi. I: The biology and therapeutic Application of mesenchymal cells. Wiley-Blackwell 2017 ISBN 978-1-118-90751-1. p. 167-190 OUS UiO Untitled

22.	Kosik-Kozioł, Alicja; Costantini, Marco; Bolek, Tomasz; Szöke, Krisztina; Barbetta, Andrea; Brinchmann, Jan E.; Święszkowski, Wojciech. PLA short sub-micron fiber reinforcement of 3D bioprinted alginate constructs for cartilage regeneration. Biofabrication 2017 ;Volume 9:044105.(4) p. 1-14 UiO OUS Untitled

23.	Szöke, Krisztina; Daňková, Jana; Buzgo, Matej; Amler, Evžen; Brinchmann, Jan E.; Østrup, Esben. The effect of medium composition on deposition of collagen type 1 and expression of osteogenic genes in mesenchymal stem cells derived from human adipose tissue and bone marrow. Process Biochemistry 2017 ;Volume 59. p. 321-328 OUS UiO Untitled

24.	Wollert, Kai C.; Meyer, Gerd P.; Müller-Ehmsen, Jochen; Tschöpe, Carsten; Bonarjee, Vernon V S; Larsen, Alf Inge; May, Andreas E.; Empen, Klaus; Chorianopoulos, Emmanuel; Tebbe, Ulrich; Waltenberger, Johannes; Mahrholdt, Heiko; Ritter, Benedikta; Pirr, Jens; Fischer, Dieter; Korf-Klingebiel, Mortimer; Arseniev, Lubomir; Heuft, Hans-Gert; Brinchmann, Jan E.; Messinger, Diethelm; Hertenstein, Bernd; Ganser, Arnold; Katus, Hugo A.; Felix, Stephan B.; Gawaz, Meinrad P.; Dickstein, Kenneth; Schultheiss, Heinz-Peter; Ladage, Dennis; Greulich, Simon; Bauersachs, Johann. Intracoronary autologous bone marrow cell transfer after myocardial infarction: The BOOST-2 randomised placebo-controlled clinical trial. European Heart Journal 2017 ;Volume 38.(39) p. 2936-2943 SUS UiB OUS Untitled
2016
25.	Karlsen, Tommy Aleksander; De Souza, Gustavo Antonio; Ødegård, Bjørn; Engebretsen, Lars; Brinchmann, Jan E.. microRNA-140 Inhibits Inflammation and Stimulates Chondrogenesis in a Model of Interleukin 1beta-induced Osteoarthritis.. Molecular Therapy Nucleic Acids 2016 ;Volume 5. p. e373- OUS UiO LDS Untitled

26.	Aae, Tommy Frøseth; Randsborg, Per-Henrik; Breen, Anne Berg; Visnes, Håvard; Vindfeld, Søren; Sivertsen, Einar; Løken, Sverre Bertrand; Brinchmann, Jan E.; Hanvold, Heidi Andreassen; Årøen, Asbjørn. Norwegian Cartilage Project - a study protocol for a double-blinded randomized controlled trail comparing arthroscopic microfracture with debridement in focal cartilage defects in the knee. BMC Musculoskeletal Disorders 2016 ;Volume 17:292. p. - OUS HAUKELAND HMR AHUS HVprivate DIAKON UiO NIH Untitled

27.	Behnan, Jinan; Stangeland, Biljana; Langella, Tiziana; Finocchiaro, Gaetano; Murrell, Wayne; Brinchmann, Jan E.. Ultrasonic Surgical Aspirate is a Reliable Source for Culturing Glioblastoma Stem Cells. Scientific Reports 2016 ;Volume 6. UiO OUS Untitled

28.	Costantini, Marco; Idaszek, Joanna; Szoke, Krisztina; Jaroszewicz, Jakub; Dentini, Mariella; Barbetta, Andrea; Brinchmann, Jan E.; Swieszkowski, Wojciech. 3D bioprinting of BM-MSCs-loaded ECM biomimetic hydrogels for in vitro neocartilage formation. Biofabrication 2016 ;Volume 8.(3) UiO OUS Untitled

29.	Foldager, Casper B.; Bendtsen, Michael; Berg, Lise C.; Brinchmann, Jan E.; Brittberg, Mats; Bunger, Cody; Canseco, Jose; Chen, Li; Christensen, Bjørn; Colombier, Pauline; Deleuran, Bent W.; Edwards, James; Elmengaard, Brian; Farr, Jack; Gatenholm, Birgitta; Gomoll, Andreas H.; Hui, James H.; Jakobsen, Rune Bruhn; Jørgensen, Natasja L.; Kassem, Moustapha; Koch, Thomas; Kold, Søren; Krogsgaard, Michael R.; Lauridsen, Henrik; Le, Dang; Le Visage, Catherine; Lind, Martin; Nygaard, Jens V.; Olesen, Morten L.; Pedersen, Michael; Rathcke, Martin; Richardson, James B.; Roberts, Sally; Rölfing, Jan H.D.; Sakai, Daisuke; Toh, Wei Seong; Urban, Jill; Spector, Myron. Aarhus Regenerative Orthopaedics Symposium (AROS): Regeneration in the ageing population. Acta Orthopaedica 2016 ;Volume 87. p. 1-5 UiO AHUS Untitled

30.	Randsborg, Per-Henrik; Brinchmann, Jan E.; Løken, Sverre Bertrand; Hanvold, Heidi Andreassen; Aae, Tommy Frøseth; Årøen, Asbjørn. Focal cartilage defects in the knee -a randomized controlled trial comparing autologous chondrocyte implantation with arthroscopic debridement. BMC Musculoskeletal Disorders 2016 ;Volume 17.(1) p. - NIH UiO HMR OUS AHUS Untitled

31.	Szoke, Krisztina; Reinisch, Andreas; Østrup, Esben; Reinholt, Finn P.; Brinchmann, Jan E.. Autologous cell sources in therapeutic vasculogenesis: In vitro and in vivo comparison of endothelial colony-forming cells from peripheral blood and endothelial cells isolated from adipose tissue. Cytotherapy 2016 ;Volume 18.(2) p. 242-252 UiO OUS Untitled
2015
32.	Hart, Melanie L.; Izeta, Ander; Herrera-Imbroda, Bernardo; Amend, Bastian; Brinchmann, Jan E.. Cell therapy for stress urinary incontinence. Tissue Engineering Part B: Reviews 2015 ;Volume 21.(4) p. 365-376 UiO OUS Untitled

33.	Klein, Gerd; Hart, Melanie L.; Brinchmann, Jan E.; Rolauffs, Bernd; Stenzl, Arnulf; Sievert, Karl-Dietrich; Aicher, Wilhelm K.. Mesenchymal stromal cells for sphincter regeneration. Advanced Drug Delivery Reviews 2015 ;Volume 82. p. 123-136 UiO OUS Untitled

34.	Lilledahl, Magnus Borstad; Magnus Østgård, Olderøy; Finnøy, Andreas; Olstad, Kristin; Brinchmann, Jan E.. Second harmonic generation imaging in tissue engineering and cartilage pathologies. Progress in Biomedical Optics and Imaging 2015 ;Volume 9329. NTNU NMBU OUS Untitled

35.	Pullisaar, Helen; Verket, Anders; Szoke, Krisztina; Tiainen, Hanna; Haugen, Håvard Jostein; Brinchmann, Jan E.; Reseland, Janne Elin; Østrup, Esben. Alginate hydrogel enriched with enamel matrix derivative to target osteogenic cell differentiation in TiO2 scaffolds. Journal of Tissue Engineering 2015 ;Volume 6. UiO OUS Untitled
2014
36.	Herlofsen, Sarah; Høiby, Torill; Cacchiarelli, Davide; Zhang, Xiaolan; Mikkelsen, Tarjei S.; Brinchmann, Jan E.. Brief report: Importance of SOX8 for in vitro chondrogenic differentiation of human mesenchymal stromal cells. Stem Cells 2014 ;Volume 32.(6) p. 1629-1635 UiO OUS Untitled

37.	Jakobsen, Rune Bruhn; Shahdafar, Aboulghassem; Reinholt, Finn P.; Brinchmann, Jan E.. Erratum to Chondrogenesis in a hyaluronic acid scaffold: Comparison between chondrocytes and MSC from bone marrow and adipose tissue (Knee Surg Sports Traumatol Arthrosc, (2010), 18, (1407-1416), 10.1007/s00167-009-1017-4). Knee Surgery, Sports Traumatology, Arthroscopy 2014 ;Volume 22.(7) p. 1711-1714 OUS Untitled

38.	Jakobsen, Rune Bruhn; Østrup, Esben; Xiaolan, Zhang; Mikkelsen, Tarjei S.; Brinchmann, Jan E.. Analysis of the effects of five factors relevant to in vitro chondrogenesis of human mesenchymal stem cells using factorial design and high throughput mRNA-profiling. PLOS ONE 2014 ;Volume 9.(5) p. - OUS UiO Untitled

39.	Karlsen, Tommy Aleksander; Jakobsen, Rune Bruhn; Mikkelsen, Tarjei S.; Brinchmann, Jan E.. microRNA-140 Targets RALA and Regulates Chondrogenic Differentiation of Human Mesenchymal Stem Cells by Translational Enhancement of SOX9 and ACAN. Stem Cells and Development 2014 ;Volume 23.(3) p. 290-304 OUS UiO Untitled

40.	Magnus Østgård, Olderøy; Lilledahl, Magnus Borstad; Beckwith, Marianne; Melvik, Jan Egil; Reinholt, Finn P.; Sikorski, Pawel; Brinchmann, Jan E.. Biochemical and Structural Characterization of Neocartilage Formed by Mesenchymal Stem Cells in Alginate Hydrogels. PLOS ONE 2014 ;Volume 9.(3) p. e91662- UiO NTNU OUS Untitled

41.	Pullisaar, Helen; Reseland, Janne Elin; Haugen, Håvard Jostein; Brinchmann, Jan E.; Østrup, Esben. Simvastatin coating of TiO2 scaffold induces osteogenic differentiation of human adipose tissue-derived mesenchymal stem cells. Biochemical and Biophysical Research Communications - BBRC 2014 ;Volume 447.(1) p. 139-144 OUS UiO Untitled

42.	Pullisaar, Helen; Verket, Anders; Szoke, Krisztina; Tiainen, Hanna; Haugen, Håvard Jostein; Brinchmann, Jan E.; Reseland, Janne Elin; Østrup, Esben. Extracellular matrix coated ceramic scaffold enhance osteoblast differentiation. Novel Biomaterials and Technology for use in Regenerative Medicine/Tissue Engineering; 2014-06-04 OUS UiO Untitled
2013
43.	Fernandes, Amilton. Tissue engineering of hyaline cartilage. A comparison between articular chondrocytes and mesenchymal stem cells. : Universitetet i Oslo 2013 86 p. NIH UiO Untitled

44.	Fernandes, Amilton Moreira; Herlofsen, Sarah; Karlsen, Tommy Aleksander; Kuchler, Axel Matthias; Fløisand, Yngvar; Brinchmann, Jan E.. Similar Properties of Chondrocytes from Osteoarthritis Joints and Mesenchymal Stem Cells from Healthy Donors for Tissue Engineering of Articular Cartilage. PLOS ONE 2013 ;Volume 8.(5) p. - UiO OUS Untitled

45.	Herlofsen, Sarah; Bryne, Jan Christian; Høiby, Torill; Wang, Li; Issner, Robbyn; Zhang, XL; Coyne, Michael J; Boyle, P; Gu, Hongcang; Meza-Zepeda, Leonardo Andrés; Collas, Philippe; Mikkelsen, Tarjei S.; Brinchmann, Jan E.. Genome-wide map of quantified epigenetic changes during in vitro chondrogenic differentiation of primary human mesenchymal stem cells. BMC Genomics 2013 ;Volume 14. p. - OUS UiO Untitled

46.	Karlsen, Tommy Aleksander; Brinchmann, Jan E.. Liposome Delivery of MicroRNA-145 to Mesenchymal Stem Cells Leads to Immunological Off-target Effects Mediated by RIG-I. Molecular Therapy 2013 ;Volume 21.(6) p. 1169-1181 UiO OUS Untitled

47.	Olderøy, Magnus Østgård; Beckwith, Marianne; Rrinholt, F P; Lilledahl, Magnus Borstad; Sikorski, Pawel; Brinchmann, Jan E.. Identification of functional structures in tissue engineered cartilage: from nm to macro scale. European Cells and Materials 2013 ;Volume 26. Suppl. 2 p. 23-23 NTNU UiO Untitled

48.	Rohban, Rokhsareh; Reinisch, Andreas; Etchart, Nathalie; Schallmoser, Katharina; Hofmann, Nicole A.; Szoke, Krisztina; Brinchmann, Jan E.; Rad, Ehsan Bonyadi; Rohde, Eva; Strunk, Dirk. Identification of an Effective Early Signaling Signature during Neo-Vasculogenesis In Vivo by Ex Vivo Proteomic Profiling. PLOS ONE 2013 ;Volume 8.(6) p. - UiO Untitled

49.	Vik-Mo, Einar O.; Nyakas, Marta Sølvi; Mikkelsen, Birthe Viftrup; Moe, Morten Carsten; Due-Tønnessen, Paulina; Suso, Else Marit Inderberg; Sæbøe-Larssen, Stein; Sandberg, Cecilie; Brinchmann, Jan E.; Helseth, Eirik; Rasmussen, Anne Marie; Lothe, Knut; Aamdal, Steinar; Gaudernack, Gustav; Kvalheim, Gunnar; Langmoen, Iver Arne. Therapeutic vaccination against autologous cancer stem cells with mRNA-transfected dendritic cells in patients with glioblastoma. Cancer Immunology and Immunotherapy 2013 ;Volume 62.(9) p. 1499-1509 OUS UiO Untitled
2012
50.	Beitnes, Jan Otto; Øie, Erik; Shahdafar, Aboulghassem; Karlsen, Tommy Aleksander; Müller, Regine; Aakhus, Svend; Reinholt, Finn P.; Brinchmann, Jan E.. Intramyocardial Injections of Human Mesenchymal Stem Cells Following Acute Myocardial Infarction Modulate Scar Formation and Improve Left Ventricular Function. Cell Transplantation 2012 ;Volume 21.(8) p. 1697-1709 OUS UiO Untitled

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