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Showing results 1-37 of 37

2020
1 Peuget, Sylvain; Zhu, J; Singh, Madhurendra; Gaetani, Massimiliano; Chen, Xinsong; Shi, Yao; Saei, Amir Ata; Visnes, Torkild; Lindström, Mikael; Rihani, A; Moyano-Galceran, Lidia; Carlson, Joseph W.; Hjerpe, Elisabeth; Joneborg, Ulrika; Lehti, Kaisa; Hartman, Johan; Helleday, Thomas; Zubarev, Roman A.; Selivanova, Galina.
Thermal proteome profiling identifies oxidative-dependent inhibition of the transcription of major oncogenes as a new therapeutic mechanism for select anticancer compounds. Cancer Research 2020
SINTEF Untitled
 
2 Sulheim, Einar; Haslene-Hox, Hanne; Visnes, Torkild.
Bridging gaps in the immunotherapeutic research pipeline. Norsk Biokjemisk Selskaps vintermøte; 2020-01-24 - 2020-01-27
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2019
3 Michel, Maurice; Visnes, Torkild; Homan, Evert; Seashore-Ludlow, Brinton; Hedenström, Mattias; Wiita, Elisee; Vallin, Karl; Paulin, Cynthia BJ; Zhang, Jiaxi; Wallner, Olov; Scobie, Martin; Schmidt, Andreas; Jenmalm-Jensen, Annika; Warpman Berglund, Ulrika; Helleday, Thomas.
Computational and Experimental Druggability Assessment of Human DNA Glycosylases. ACS Omega 2019 ;Volume 4.(7) p. 11642-11656
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4 Visnes, Torkild.
High-throughput screening to characterize and exploit cancer cell vulnerabilities. Seminar: Precision medicine; 2019-12-18 - 2019-12-18
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5 Visnes, Torkild.
OGG1 inhibition as a novel strategy to treat inflammation and cancer. Norwegian Biochemical Society Winter Meeting; 2019-01-24 - 2019-01-26
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6 Visnes, Torkild.
OGG1 inhibition as a novel strategy to treat inflammation and cancer. European Chemical Biology Symposium; 2019-04-03 - 2019-04-05
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2018
7 Benjaminsen, Christina; Visnes, Torkild.
Oppdaget ny behandling mot lungebetennelse. Gemini [Internet] 2018-11-16
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8 Holsbøvåg, Kjell Ove; Visnes, Torkild.
Nordmøringen kan revolusjonere behandingen av lungebetennelse og andre sykdommer. Tidens Krav [Newspaper] 2018-11-26
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9 Rønningen, Elise; Visnes, Torkild.
Sintef-forsker har oppdaget ny behandling mot lungebetennelse. Adresseavisen [Newspaper] 2018-11-16
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10 Schølberg, Ulla Gjeset; Visnes, Torkild; Benjaminsen, Christina.
Forskere oppdaget ny behandling mot lungebetennelse. forskning.no [Internet] 2018-11-16
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11 Visnes, Torkild; Armando, Cazares-Körner; Wenjing, Hao; Wallner, Olov; Masuyer, Geoffrey; Loseva, Olga; Mortusewicz, Oliver; Wiita, Elisee; Sarno, Antonio; Manoilov, Aleksandr; Astorga-Wells, Juan; Jemth, Ann-Sofie; Pan, Lang; Sanjiv, Kumar; Karsten, Stella; Gokturk, Camilla; Grube, Maurice; Evert J, Homan; Hanna, Bishoy Magdi Fekry; Cynthia, Paulin BJ; Pham, Therese; Rasti, Azita; Warpman Berglund, Ulrika; von Nikolai, Catharina; Benitez-Buelga, Carlos; Koolmeister, Tobias; Ivanic, Dag; Iliev, Petar; Scobie, Martin; Krokan, Hans Einar; Baranczewski, Pawel; Artursson, Per; Altun, Mikael; Jenmalm-Jensen, Annika; Kalderen, Christina; Ba, Xueqing; Zubarev, Roman A.; Stenmark, Pål; Boldogh, Istvan; Helleday, Thomas.
Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation. Science 2018 ;Volume 362.(6416) p. 834-839
NTNU SINTEF Untitled
 
12 Visnes, Torkild; Grube, Maurice; Magdy Fekry Hanna, Bishoy; Benitez-Buelga, Carlos; Cazares-Körner, Armando; Helleday, Thomas.
Targeting BER enzymes in cancer therapy. DNA Repair 2018 ;Volume 71. p. 118-126
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2017
13 Puisac, Beatrice; Teresa-Rodrigo, ME; Hernandez-Marcos, M; Baquero-Montoya, C; Rodriguex, MC; Visnes, Torkild; Bot, C.; Gomez-Puertas, Paulino; Kaiser, FJ; Ramos, FJ; Ström, Lena; Pie, Juan.
mRNA Quantification of NIPBL Isoforms A and B in Adult and Fetal Human Tissues, and a Potentially Pathological Variant Affecting Only Isoform A in Two Patients with Cornelia de Lange Syndrome.. International Journal of Molecular Sciences 2017
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2016
14 Eshtad, Saeed; Mavajian, Zahra; Rudd, Sean G; Visnes, Torkild; Boström, Johan; Altun, Mikael; Helleday, Thomas.
hMYH and hMTH1 cooperate for survival in mismatch repair defective T-cell acute lymphoblastic leukemia.. Oncogenesis 2016 ;Volume 5.(12)
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15 Llona-Minguez, Sabin; Höglund, Andreas; Jacques, S; Johansson, Lars; Calderon-Montano, JM; Claesson, M; Loseva, Olga; Valerie, Nick; Lundbäck, Thomas; Piedrafita, J; Maga, Giovanni; Crespan, E; Meijer, Laurent; Moron, EB; Baranczewski, Pawel; Hagbjörk, AL; Svensson, R; Wiita, Elisee; Almlof, Ingrid; Visnes, Torkild; Jeppson, F; Sigmundsson, Kristmundur; Jenmalm-Jensen, Annika; Artursson, Per; Jemth, Ann-Sofie; Stenmark, Pål; Warpman Bergliund, Ulrika; Scobie, Martin; Helleday, Thomas.
Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1.. Journal of Medicinal Chemistry 2016 ;Volume 59.(3) p. 1140-1148
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16 Warpman Bergliund, Ulrika; Sanjiv, Kumar; Gad, Helge; Kalderen, Christina; Koolmeister, Tobias; pham, Therese; Gokturk, Camilla; Jafari, R; Maddalo, G; Seashore-Ludlow, Brinton; Cernobrovkin, A; Manoilov, Aleksandr; Pateras, IS; Rasti, Azita; Jemth, Ann-Sofie; Almlof, Ingrid; Loseva, Olga; Visnes, Torkild; Einarsdottir, BO; Gaugaz, Fabienne; Saleh, A; Platzack, Björn; Wallner, Olov; Vallin, K; Henriksson, Martin; Wakchaure, P; Borhade, S; Kallberg, Yvonne; Baranczewski, Pawel; Homan, Evert; Wiita, Elisee; Meijer, T; Schipper, N; Rudd, Sean G; Bräutigam, Lars; Lindqvist, Arne; Flippula, A; Lee, TC; Artursson, Per; Nilsson, JA; Lehtio, Janne; Zubarev, Roman A.; Scobie, Martin; Helleday, Thomas.
Validation and development of MTH1 inhibitors for treatment of cancer.. Annals of Oncology 2016 ;Volume 27.(12) p. 2275-2283
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2015
17 Pettersen, Henrik Sahlin; Galashevskaya, Anastasia; Doseth, Berit; Sousa, Mirta; Sarno, Antonio; Visnes, Torkild; Aas, Per Arne; Liabakk, Nina-Beate; Slupphaug, Geir; Sætrom, Pål; Kavli, Bodil Merete; Krokan, Hans Einar.
AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature. DNA Repair 2015 ;Volume 25. p. 60-71
NTNU STO Untitled
 
2014
18 Dahlberg, CI; He, Minghui; Visnes, Torkild; Torres, ML; Cortizas, EM; Verdun, RE; Westerberg, LS; Severinson, E; Ström, Lena.
A novel mouse model for the hyper-IgM syndrome: a spontaneous activation-induced cytidine deaminase mutation leading to complete loss of Ig class switching and reduced somatic hypermutation.. Journal of Immunology 2014
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19 Orta, ML; Höglund, Andreas; Calderon-Montano, JM; Domínguez, I.; Burgos-Moron, E; Visnes, Torkild; Pastor, Nuria; Stöm, Cecilia; Lopez-lazaro, M; Helleday, Thomas.
The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2'-deoxycytidine lesions.. Nucleic Acids Research 2014 ;Volume 42.(14) p. 9108-9120
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20 Visnes, Torkild; Giordano, Fosco; Kuznetsova, Anna; suja, JA; Lander, AD; Calof, AL; Ström, Lena.
Localisation of the SMC loading complex Nipbl/Mau2 during mammalian meiotic prophase I.. Chromosoma 2014
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2013
21 enervald, Elin; Du, Likun; Visnes, Torkild; Björkman, Andrea; Wincent, Jacqueline; Borck, Guntram; Colleaux, Laurence; Cormier-Daire, Valerie; van gent, Dik C; Pie, Juan; Puisac, Beatrice; de miranda, noel fcc; kracker, sven; Hammarström, Lennart; de villartay, jean-pierre; Durandy, Anne; Schoumans, Jacqueline; Ström, Lena; Pan-Hammarström, Q.
A regulatory role for the cohesin loader NIPBL in nonhomologous end joining during immunoglobulin class switch recombination. Journal of Experimental Medicine 2013
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2011
22 Doseth, Berit; Visnes, Torkild; Wallenius, Anders; Ericsson, Ida; Sarno, Antonio; Pettersen, Henrik Sahlin; Flatberg, Arnar; Catterall, Tara Cherie; Slupphaug, Geir; Krokan, Hans Einar; Kavli, Bodil Merete.
Uracil-DNA Glycosylase in Base Excision Repair and Adaptive Immunity: SPECIES DIFFERENCES BETWEEN MAN AND MOUSE. Journal of Biological Chemistry 2011 ;Volume 286.(19) p. 16669-16680
NTNU Untitled
 
23 Pettersen, Henrik Sahlin; Visnes, Torkild; Vågbø, Cathrine Broberg; Svaasand, Eva K; Doseth, Berit; Slupphaug, Geir; Kavli, Bodil Merete; Krokan, Hans Einar.
UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation. Nucleic Acids Research 2011 ;Volume 39.(19) p. 8430-8444
NTNU Untitled
 
24 Pettersen, Henrik Sahlin; Visnes, Torkild; Vågbø, Cathrine Broberg; Svaasand, Eva K; Doseth, Berit; Slupphaug, Geir; Kavli, Bodil Merete; Krokan, Hans Einar.
UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation. 4th EU-USA conference on DNA base damage and repair; 2011-05-18 - 2011-05-22
NTNU Untitled
 
2009
25 Henrik Sahlin, Pettersen; Visnes, Torkild; Vågbø, Cathrine Broberg; Kavli, Bodil Merete; Krokan, Hans Einar.
Cytotoxicity of 5-fluorouracil is mainly due to RNA effects and thymidylate synthase inhibition, not excessive DNA repair. 2nd Erling Seeberg Symposium on DNA Repair; 2009-06-20 - 2009-06-25
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26 ; Visnes, Torkild.
DNA Excision repair of uracil and 5-fluorouracil in human cancer cell lines. Trondheim: Det medisinske fakultet, NTNU 2009 (ISBN 978-82-471-1936-5) 146 p.
NTNU Untitled
 
27 Krokan, Hans Einar; Visnes, Torkild; Doseth, Berit; Akbari, Mansour; Otterlei, Marit; Kavli, Bodil Merete; Slupphaug, Geir.
Uracil in DNA and its processing. 3rd US-EU Conference- Repair of Endogenous Genome Damage; 2009-02-21 - 2009-02-25
NTNU Untitled
 
28 Slupphaug, Geir; Doseth, Berit; Kavli, Bodil Merete; Visnes, Torkild; Hagen, Lars; Torseth, Kathrin; Pettersen, Henrik Sahlin; Akbari, Mansour; Otterlei, Marit; Krokan, Hans Einar.
Genomic uracil processing in mice and men. 2.nd Erling Seeberg symposium on DNA repair; 2009-06-20 - 2009-06-25
NTNU Untitled
 
29 Visnes, Torkild; Doseth, Berit; Pettersen, Henrik Sahlin; Hagen, Lars; Sousa, Mirta; Akbari, Mansour; Otterlei, Marit; Kavli, Bodil Merete; Slupphaug, Geir; Krokan, Hans Einar.
Uracil in DNA and its processing by different DNA glycosylases. Philosophical Transactions of the Royal Society of London. Biological Sciences 2009 ;Volume 364.(1517) p. 563-568
NTNU Untitled
 
2008
30 Akbari, Mansour; Visnes, Torkild; Krokan, Hans Einar; Otterlei, Marit.
Mitochondrial base excision repair of uracil and AP sites takes place by single-nucleotide insertion and long-patch DNA synthesis. DNA Repair 2008 ;Volume 7. p. 605-616
NTNU Untitled
 
31 Visnes, Torkild; Akbari, Mansour; Hagen, Lars; Slupphaug, Geir; Krokan, Hans Einar.
The rate of base excision repair of uracil is controlled by the initiating glycosylase. DNA Repair 2008 ;Volume 7.(11) p. 1869-1881
NTNU Untitled
 
2007
32 Krokan, Hans Einar; Kavli, Bodil Merete; Akbari, Mansour; Visnes, Torkild; Pettersen, Henrik P Sahlin; Sundheim, Ottar; Hagen, Lars; Otterlei, Marit; Gilljam, Karin Margaretha; Slupphaug, Geir.
Repair og uracil in DNA by UNG2 and SMUG1 - an update. DNA Repair 2007 p. 39-
NTNU Untitled
 
33 Visnes, Torkild.
Bottlenecks in base excision repair:Using variability of protein expression in cancer cells to investigate bottlenecks in base excision repair of uracil and its repair intermediates. tirsdagsseminar ved ikmm; 2007-11-27 - 2007-11-27
NTNU Untitled
 
34 Visnes, Torkild; Kavli, Bodil Merete; Pettersen, Henrik P Sahlin; Krokan, Hans Einar.
Efficient repair of 5-fluorouracil from DNA by base excision repair: roles of UNG2 and SMUG1. EU - IP DNA Repair workshop for young scientists; 2007-05-13 - 2007-05-16
NTNU Untitled
 
2003
35 Visnes, Torkild.
Base Excision Repair in Human Cancer Cells. : [Mangler utgivernavn] 2003
NTNU Untitled
 
2002
36 Visnes, Torkild; Vågbø, Cathrine; Akbari, Mansour; Krokan, Hans Einar.
The signifisance of variation of uracil DNA.glycosylase activity on uracil initiated base exicion repair. 38. Biokjemiske kontaktmøte Functinal genomics - the mosaics of life; 2002-01-20
NTNU Untitled
 
37 Visnes, Torkild; Vågbø, Cathrine; Akbari, Mansour; Krokan, Hans Einar.
To BER or not to BER - is that the question?. Norsk Biokjemisk Selskaps Vintermøte; 2002-01-20
NTNU Untitled