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Showing results 1-50 of 153
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2024
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1. |
Singleton, Amanda Holstad; Otterlei, Marit. Nytt verktøy i jakten på nye antibiotikakandidater. Bioingeniøren 2024 ;Volume 59.(2) p. 26-27 NTNU
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2023
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Rocque, Mariève; Leipart, Vilde; Singh, Ashish Kumar; Mur, Pilar; Olsen, Maren Fridtjofsen; Engebretsen, Lars Fredri; Martin-Ramos, Edgar; Aligué, Rosa; Sætrom, Pål; Valle, Laura; Drabløs, Finn Sverre; Otterlei, Marit; Sjursen, Wenche. Characterization of POLE c.1373A > T p.(Tyr458Phe), causing high cancer risk. Molecular Genetics and Genomics 2023 ;Volume 298. p. 555-566 NTNU STO NMBU
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Singleton, Amanda Holstad; Bergum, Olaug Elisabeth Torheim; Søgaard, Caroline Krogh; Røst, Lisa M.; Olsen, Cecilie Elisabeth; Blindheim, Fredrik Heen; Ræder, Synnøve Brandt; Bjørnstad, Frithjof Andreas; Sundby, Eirik; Hoff, Bård Helge; Bruheim, Per; Otterlei, Marit. Activation of multiple stress responses in Staphylococcus aureus substantially lowers the minimal inhibitory concentration when combining two novel antibiotic drug candidates. Frontiers in Microbiology 2023 ;Volume 14. p. - NTNU
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2022
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Lemech, Charlotte Rose; Kichenadasse, Ganessan; Marschner, Jens-Peter; Alevizopoulos, Konstantinos; Otterlei, Marit; Millward, Michael. ATX-101, a cell-penetrating protein targeting PCNA, can be safely administered as intravenous infusion in patients and shows clinical activity in a Phase 1 study. Oncogene 2022 p. - NTNU
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Olsen, Cecilie Elisabeth; Blindheim, Fredrik Heen; Søgaard, Caroline Krogh; Røst, Lisa M.; Singleton, Amanda; Bergum, Olaug Elisabeth Torheim; Bruheim, Per; Otterlei, Marit; Sundby, Eirik; Hoff, Bård Helge. Halogenated Pyrrolopyrimidines with Low MIC on Staphylococcus aureus and Synergistic Effects with an Antimicrobial Peptide. Antibiotics 2022 ;Volume 11.(8) p. - NTNU
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Gravina, Giovanni Luca; Colapietro, Alessandro; Andrea, Mancini; Rossetti, Alessandra; Martelucci, Stefano; Ventura, Luca; Di Franco, Martina; Marampon, Francesco; Mattei, Vinvenzo; Biordi, Leda Assunta; Otterlei, Marit; Festuccia, Claudio. ATX-101, a Peptide Targeting PCNA, Has Antitumor Efficacy Alone or in Combination with Radiotherapy in Murine Models of Human Glioblastoma. Cancers 2022 NTNU
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Røst, Lisa M.; Ræder, Synnøve Brandt; Olaisen, Camilla; Søgaard, Caroline Krogh; Sharma, Animesh; Bruheim, Per; Otterlei, Marit. PCNA regulates primary metabolism by scaffolding metabolic enzymes. Oncogene 2022 p. - NTNU STO
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2021
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8. |
Blindheim, Fredrik Heen; Olsen, Cecilie Elisabeth; Søgaard, Caroline Krogh; Otterlei, Marit; Sundby, Eirik; Hoff, Bård Helge. Synthetic Strategies towards Imidazopyridinones and 7-Azaoxindoles and their Evaluation as Antibacterial Agents. European Journal of Organic Chemistry 2021 (18) p. 2702-2712 NTNU
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Frimodt-Møller, Jakob; Koulouktsis, Andreas; Charbon, Godefroid; Otterlei, Marit; Nielsen, Peter E.; Løbner-Olesen, Anders. Activating the Cpx response induces tolerance to antisense PNA delivered by an arginine-rich peptide in Escherichia coli. Molecular Therapy Nucleic Acids 2021 ;Volume 25. p. 444-454 NTNU
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Nepal, Anala; Ræder, Synnøve Brandt; Søgaard, Caroline Krogh; Haugan, Maria Schei; Otterlei, Marit. Broad-Spectrum Antibacterial Peptide Kills Extracellular and Intracellular Bacteria Without Affecting Epithelialization. Frontiers in Microbiology 2021 NTNU STO
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11. |
Ræder, Synnøve Brandt; Sandbakken, Erik Thorvaldsen; Nepal, Anala; Løseth, Kirsti; Bergh, Kåre; Witsø, Eivind; Otterlei, Marit. Novel Peptides Targeting the β-Clamp Rapidly Kill Planktonic and Biofilm Staphylococcus epidermidis Both in vitro and in vivo. Frontiers in Microbiology 2021 STO NTNU
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Strømme, Olaf; Heck, Kathleen; Brede, Gaute; Lindholm, Håvard Takle; Otterlei, Marit; Arum, Carl-Jørgen. Differentially expressed extracellular vesicle-contained micrornas before and after transurethral resection of bladder tumors. Current Issues in Molecular Biology 2021 ;Volume 43.(1) p. 286-300 NTNU STO
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Sumabe, Balagra Kasim; Ræder, Synnøve Brandt; Røst, Lisa M.; Sharma, Animesh; Donkor, Eric S.; Mosi, Lydia; Duodu, Samuel; Bruheim, Per; Otterlei, Marit. Nucleoside Analogues Are Potent Inducers of Pol V-mediated Mutagenesis. Biomolecules 2021 ;Volume 11.(6) p. - NTNU STO
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2020
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14. |
Nedal, Aina; Ræder, Synnøve Brandt; Dalhus, Bjørn; Helgesen, Emily; Forstrøm, Rune Johansen; Lindland, Kim; Sumabe, Balagra Kasim; Martinsen, Jacob H.; Kragelund, Birthe B.; Skarstad, Kirsten Jane; Bjørås, Magnar; Otterlei, Marit. Peptides containing the PCNA interacting motif APIM bind to the beta-clamp and inhibit bacterial growth and mutagenesis. Nucleic Acids Research (NAR) 2020 ;Volume 48.(10) p. 5540-5554 OUS UiO NTNU
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Seelinger, Mareike; Søgaard, Caroline Krogh; Otterlei, Marit. The human RAD5 homologs, HLTF and SHPRH, have separate functions in DNA damage tolerance dependent on the DNA lesion type. Biomolecules 2020 ;Volume 10.(3) NTNU
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Røst, Lisa Marie. Targeted Mass Spectrometric Metabolite Profiling for Studies of Central Carbon Metabolism. Norges teknisk-naturvitenskapelige universitet 2020 (ISBN 978-82-326-4737-8) 180 p. NTNU
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17. |
Seelinger, Mareike; Otterlei, Marit. Helicase-Like Transcription Factor HLTF and E3 Ubiquitin Ligase SHPRH Confer DNA Damage Tolerance through Direct Interactions with Proliferating Cell Nuclear Antigen (PCNA). International Journal of Molecular Sciences 2020 ;Volume 21.(693) p. - NTNU
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2019
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18. |
Montaldo, Nicola Pietro; Bordin, Diana Lilian; Brambilla, Alessandro; Rösinger, Marcel; Martin, Sarah Fordyce; Bjørås, Karine Øian; Bradamante, Stefano; Aas, Per Arne; Furrer, Antonia; Olsen, Lene Christin; Kunath, Nicolas; Otterlei, Marit; Sætrom, Pål; Bjørås, Magnar; Samson, Leona D.; van Loon, Barbara. Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression. Nature Communications 2019 ;Volume 10.(1) p. - NTNU UiO OUS
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19. |
Prestel, Andreas; Wichmann, Nanna; Martins, Joao M; Marabini, Riccardo; Kassem, Noah; Broendum, Sebastian S; Otterlei, Marit; Nielsen, Olaf; Willemoës, Martin; Ploug, Michael; Boomsma, Wouter; Kragelund, Birthe B. The PCNA interaction motifs revisited: thinking outside the PIP-box. Cellular and Molecular Life Sciences (CMLS) 2019 ;Volume 76.(24) p. 4923-4943 NTNU
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20. |
Prikrylova, Terezia; Robertson, Julia; Ferrucci, Francesca; Konorska, Dorota Joanna; Aanes, Håvard; Manaf, Adeel; Zhang, Beibei; Vågbø, Cathrine Broberg; Kusnierczyk, Anna; Gilljam, Karin Margaretha; Løvkvam-Køster, Maiken Caroline; Otterlei, Marit; Dahl, John Arne; Enserink, Jorrit; Klungland, Arne; Robertson, Adam Brian. 5-hydroxymethylcytosine marks mammalian origins acting as a barrier to replication. Scientific Reports 2019 ;Volume 9. p. - UiO OUS NTNU
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Røst, Lisa Marie; Løkken, Erle Gustavsen; Otterlei, Marit; Bruheim, Per. Glioblastoma cells respond to hypoxia by increased cell growth and altered TCA-cycle progression. NBS Vintermøte; 2019-01-24 - 2019-01-27 NTNU
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22. |
Søgaard, Caroline Krogh; Nepal, Anala; Petrovic, Voin; Sharma, Animesh; Liabakk, Nina-Beate; Steigedal, Tonje S.; Otterlei, Marit. Targeting the non-canonical roles of PCNA modifies and increases the response to targeted anti-cancer therapy. OncoTarget 2019 ;Volume 10.(68) p. 7185-7197 NTNU STO
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2018
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23. |
Kim, Jana; Søgaard, Caroline Krogh; Kim, Eugene; Bathen, Tone Frost; Otterlei, Marit; Moestue, Siver Andreas; Hill, Deborah Katherine. Diffusion weighted MRI simplifies therapy monitoring in TRAMP mice. Joint Annual Meeting ISMRM-ESMRMB; 2018-06-16 - 2018-06-21 NTNU
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24. |
Olaisen, Camilla; Kvitvang, Hans Fredrik Nyvold; Lee, Sungmin; Almaas, Eivind; Bruheim, Per; Drabløs, Finn; Otterlei, Marit. The role of PCNA as a scaffold protein in cellular signaling is functionally conserved between yeast and humans. FEBS Open Bio 2018 ;Volume 8.(7) p. 1135-1145 NTNU
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25. |
Olaisen, Camilla; Røst, Lisa Marie; Nedal, Aina; Petrovic, Voin; Kvitvang, Hans Fredrik Nyvold; Bruheim, Per; Otterlei, Marit. Proliferating Cell Nuclear Antigen (PCNA) has a Central Role in Regulation of the Glycolysis in Haematological Cancer Cells. Metabolism and Cancer; 2018-09-28 - 2018-10-01 NTNU
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26. |
Petrovic, Voin; Nepal, Anala; Olaisen, Camilla; Bachke, Siri; Hira, Jonathan; Søgaard, Caroline Krogh; Røst, Lisa Marie; Misund, Kristine; Andreassen, Trygve; Melø, Torun Margareta; Bartosova, Zdenka; Bruheim, Per; Otterlei, Marit. Anti-Cancer Potential of Homemade Fresh Garlic Extract Is Related to Increased Endoplasmic Reticulum Stress. Nutrients 2018 ;Volume 10.(4) UiT NTNU
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27. |
Ræder, Synnøve Brandt; Nepal, Anala; Bjørås, Karine; Seelinger, Mareike; Kolve, Rønnaug Steen; Nedal, Aina; Müller, Rebekka; Otterlei, Marit. APIM-mediated REV3L?PCNA interaction important for error free TLS over UV-induced DNA lesions in human cells. International Journal of Molecular Sciences 2018 ;Volume 20.(1) p. - STO NTNU
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28. |
Søgaard, Caroline Danielsen; Moestue, Siver Andreas; Rye, Morten Beck; Kim, Jana; Nepal, Anala; Liabakk, Nina-Beate; Bachke, Siri; Bathen, Tone Frost; Otterlei, Marit; Hill, Deborah Katherine. APIM-peptide targeting PCNA improves the efficacy of docetaxel treatment in the TRAMP mouse model of prostate cancer. OncoTarget 2018 ;Volume 9.(14) p. 11752-11766 STO NORD NTNU
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29. |
Søgaard, Caroline Krogh; Blindheim, Augun; Røst, Lisa Marie; Petrovic, Voin; Nepal, Anala; Bachke, Siri; Liabakk, Nina-Beate; Gederaas, Odrun Arna; Viset, Trond; Arum, Carl-Jørgen; Bruheim, Per; Otterlei, Marit. "Two hits - one stone" increased efficacy of cisplatin-based therapies by targeting PCNA's role in both DNA repair and cellular signaling. OncoTarget 2018 ;Volume 9.(65) p. 32448-32465 NTNU STO
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2017
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30. |
Bjørås, Karine; Sousa, Mirta; Sharma, Animesh; Fonseca, Davi de Miranda; Søgaard, Caroline Danielsen; Bjørås, Magnar; Otterlei, Marit. Monitoring of the spatial and temporal dynamics of BER/SSBR pathway proteins, including MYH, UNG2, MPG, NTH1 and NEIL1-3, during DNA replication. Nucleic Acids Research (NAR) 2017 ;Volume 45.(14) p. 8291-8301 OUS NTNU UiO
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Petrovic, Voin; Olaisen, Camilla; Sharma, Animesh; Nepal, Anala; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge; Slupphaug, Geir; Otterlei, Marit. Changes in cellular signaling proteins in extracts from A549, H460, and U2OS cells treated with cisplatin or docetaxel. Data in Brief 2017 ;Volume 12. p. 18-21 NTNU
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Petrovic, Voin; Olaisen, Camilla; Sharma, Animesh; Nepal, Anala; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge; Slupphaug, Geir; Otterlei, Marit. On-column trypsinization allows for re-use of matrix in modified multiplexed inhibitor beads assay. Analytical Biochemistry 2017 ;Volume 523. p. 10-16 NTNU
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33. |
Sousa, Mirta; Bjørås, Karine; Hanssen-Bauer, Audun; Solvang-Garten, Karin; Otterlei, Marit. P38 MAPK signaling and phosphorylations in the BRCT1 domain regulate XRCC1 recruitment to sites of DNA damage. Scientific Reports 2017 ;Volume 7.(1) NTNU
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2016
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34. |
Marstad, Anne; Landsverk, Ole J. B.; Strømme, Olaf; Otterlei, Marit; Collas, Philippe; Sundan, Anders; Brede, Gaute. A-kinase anchoring protein AKAP95 is a novel regulator of ribosomal RNA synthesis. The FEBS Journal 2016 ;Volume 283.(4) p. 757-770 OUS UiO NTNU
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35. |
Røst, Lisa Marie; Olaisen, Camilla; Petrovic, Voin; Otterlei, Marit; Bruheim, Per. Blocking the Stress-specific APIM-PCNA Interaction in Multiple Myeloma Cells Cause Significant Changes in Central Carbon Metabolism. ISCaM 2016: Metabolic Networks in Cancer; 2016-10-26 - 2016-10-29 NTNU
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36. |
Søgaard, Caroline Danielsen; Petrovic, Voin; Blindheim, Augun; Gederaas, Odrun Arna; Arum, Carl-Jørgen; Otterlei, Marit. PCNA-targeting APIM-peptide alters response to DNA damage in human bladder cancer cells on a signaling level. 2nd EMBO Cellular Signalling & Cancer Therapy Conference; 2016-05-27 - 2016-05-31 NTNU
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2015
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37. |
Olaisen, Camilla; Müller, Rebekka; Nedal, Aina; Otterlei, Marit. PCNA-interacting peptides reduce Akt phophorylation and TLR-mediated cytokine secretion suggesting a role of PCNA in cellular signaling. Cellular Signalling 2015 ;Volume 27.(7) p. 1478-1487 NTNU
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2014
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38. |
Baglo, Yan; Hagen, Lars; Høgset, Anders; Drabløs, Finn; Otterlei, Marit; Gederaas, Odrun Arna. Enhanced efficacy of bleomycin in bladder cancer cells by photochemical internalization. BioMed Research International 2014 ;Volume 14.(74) p. - NTNU
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39. |
Gederaas, Odrun Arna; Søgaard, Caroline Danielsen; Viset, Trond; Bachke, Siri; Bruheim, Per; Arum, Carl-Jørgen; Otterlei, Marit. Increased anticancer efficacy of intravesical mitomycin C therapy when combined with a PCNA targeting peptide. Translational Oncology 2014 ;Volume 7.(6) p. 812-823 STO NTNU
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2013
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40. |
Hegre, Siv Anita; Sætrom, Pål; Aas, Per Arne; Pettersen, Henrik P Sahlin; Otterlei, Marit; Krokan, Hans Einar. Multiple microRNAs may regulate DNA repair enzyme uracil‐DNA glycosylase. DNA Repair 2013 ;Volume 12.(1) p. 80-86 NTNU
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41. |
Müller, Rebekka; Misund, Kristine; Holien, Toril; Bachke, Siri; Gilljam, Karin Margaretha; Våtsveen, Thea Kristin; Rø, Torstein Baade; Bellacchio, E.; Sundan, Anders; Otterlei, Marit. Targeting Proliferating Cell Nuclear Antigen and Its Protein Interactions Induces Apoptosis in Multiple Myeloma Cells. PLOS ONE 2013 ;Volume 8.(7) p. - NTNU
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2012
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Arum, Carl-Jørgen; Gederaas, Odrun; Bachke, Siri; Viset, Trond; Otterlei, Marit. Targeting DNA repair mechanisms increases efficiency of intravesical chemotherapy in an orthotopic rat bladder model. info kommer; 2012-11-30 - 2012-11-30 NTNU STO
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43. |
Bjørnstad, Linn; Meza, Trine Johansen; Otterlei, Marit; Olafsrud, Solveig Mjelstad; Meza-Zepeda, Leonardo Andrés; Falnes, Pål. Human ALKBH4 Interacts with Proteins Associated with Transcription. PLOS ONE 2012 ;Volume 7.(11) p. - NTNU UiO OUS
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44. |
Gederaas, Odrun; Bachke, Siri; Sørgaard, Caroline Danielsen; Viset, Trond; Arum, Carl-Jørgen; Otterlei, Marit. Increased efficacy of intravesical chemotherapy in an orthotopic rat bladder cancer model by targeting PCNA with the novel synthetic peptide drug ATX-101. Congress, USA. Urology (korrekt navn blir supplert); 2012-11-30 - 2012-11-30 NTNU STO UiT
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45. |
Gilljam, Karin Margaretha; Müller, Rebekka; Liabakk, Nina-Beate; Otterlei, Marit. Nucleotide excision repair is associated with the replisome and its efficiency depends on a direct interaction between XPA and PCNA. PLOS ONE 2012 ;Volume 7.(11) p. - NTNU
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46. |
Hanssen-Bauer, Audun; Solvang-Garten, Karin; Akbari, Mansour; Otterlei, Marit. X-ray repair cross complementing protein 1 in base excision repair. International Journal of Molecular Sciences 2012 ;Volume 13.(12) p. 17210-17229 NTNU
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47. |
Hanssen-Bauer, Audun; Solvang-Garten, Karin; Gilljam, Karin Margaretha; Torseth, Kathrin; Wilson, David M.; Akbari, Mansour; Otterlei, Marit. The region of XRCC1 which harbours the three most common nonsynonymous polymorphic variants, is essential for the scaffolding function of XRCC1. DNA Repair 2012 ;Volume 11.(4) p. 357-366 NTNU
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48. |
Otterlei, Marit. APIM-peptides targeting PCNA induce apoptosis in cancer cells. The 3rd Erling Seeberg Symposium on DNA Repair; 2012-07-19 - 2012-07-23 NTNU
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49. |
Otterlei, Marit; Müller, R.; Gilljam, Karin Margaretha; Holien, Toril; Midsund, K.; Vatsveen, TK; Ro, T.B.; Bellacchio, E.; Sundan, Anders. PEPTIDES COMPRISING THE NOVEL PCNA INTERACTING SEQUENCE APIM, INCREASES THE CYTOTOXICITY OF CHEMOTHERAPEUTIC DRUGS BY IMPAIRING THE CELLS DEFENSE MECHANISMS. Annals of Oncology 2012 ;Volume 23. p. 37-37 NTNU
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50. |
Torseth, Kathrin; Doseth, Berit; Hagen, Lars; Olaisen, Camilla; Liabakk, Nina-Beate; Græsmann, Heidi; Durandy, Anne; Otterlei, Marit; Krokan, Hans Einar; Kavli, Bodil Merete; Slupphaug, Geir. The UNG2 Arg88Cys variant abrogates RPA-mediated recruitment of UNG2 to single-stranded DNA. DNA Repair 2012 ;Volume 11.(6) p. 559-569 NTNU
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